Clinical Trials on Oropharynx

Total 215 results

Brooke Army Medical Center

Completed

Do Traditional or Flavored Tongue Depressors Make for Easier Posterior Oropharynx Exams in Pediatric Patients

Oropharynx
University Hospital, Basel, Switzerland

Recruiting

Reinnervated PAP Flap for Oral Cavity and Oropharyngeal Defect Reconstruction

Oral Cavity Defect | Oropharynx Defect

Switzerland
Region Skane
Lund University

Completed

Probiotics Against Pathogenic Bacteria in Advanced ENT-Surgery

Advanced ENT Surgery | Microbiological Flora in the Oropharynx and Lower Airways

Sweden
Memorial Sloan Kettering Cancer Center

Withdrawn

Cardiopulmonary Fitness in Long-Term Survivors of HPV-related Oropharynx Cancers

Oropharynx Cancers
University of Chicago
National Cancer Institute (NCI)

Terminated

Patient Preferences in Making Treatment Decisions in Patients With Stage I-IVA Oropharyngeal Cancer

Tongue Cancer | Stage I Squamous Cell Carcinoma of the Oropharynx | Stage II Squamous Cell Carcinoma of the Oropharynx | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx

United States
Emory University
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

Pre-operative Atezolizumab in Patients With Resectable, Human Papillomavirus Related Oropharyngeal Carcinoma

Oropharynx Cancer, Stage I

United States
Bahaa Mohammed Refaie

Completed

Foreign Body Swallows in Pediatrics

Foreign Body in Oropharynx

Egypt
University of Liverpool

Not yet recruiting

PuraBond® and Pain Following Resection of Oral or Oropharyngeal Mucosal Lesions (PuraBond PROOF)

Pain | Hemorrhage | Oral Cavity | Hemostatics | Oropharynx

United Kingdom
Eye & ENT Hospital of Fudan University

Recruiting

An Observational Study of Clinical Treatments for Patients With Oropharyngeal Carcinoma

Oropharynx Carcinoma

China
Duke University

Recruiting

Radiotherapy Dose De-escalation in HPV-Associated Cancers of the Oropharynx

Oropharynx Cancer

United States
Icahn School of Medicine at Mount Sinai

Active, not recruiting

Quarterback 2b - Sequential Therapy With Reduced Dose Chemoradiotherapy for HPV Oropharynx Cancer

Locally Advanced HPV Positive Oropharynx Cancer

United States
Memorial Sloan Kettering Cancer Center

Completed

Long-Term Impact of Human Papillomavirus (HPV) on Quality of Life

Squamous Cell Carcinoma of the Oropharynx

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Withdrawn

Radiation Therapy and Cisplatin With or Without Surgery in Treating Patients With Stage III-IV Oropharyngeal Cancer

Tongue Cancer | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx

United States
Loren Mell, MD
Merck Sharp & Dohme LLC

Recruiting

Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer

Cancer | Head and Neck Squamous Cell Carcinoma | Oral Cancer | Tumor | Oropharynx Cancer | Cancer of Head and Neck | Oropharyngeal Cancer | Cancer, Advanced | Cancer, Metastatic | Tumor Metastasis | Tumor Recurrence | Tumor Neck | Oropharynx Cancer, Stage III | Oropharynx Cancer, Recurrent | Oropharynx Cancer, Metastatic

United States
National Cancer Institute (NCI)

Completed

Erlotinib and Radiation Therapy With or Without Cisplatin in Treating Patients With Mouth or Throat Cancer

Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage II Squamous Cell Carcinoma of the Oropharynx | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity and other conditions

United States
Tata Medical Center

Completed

Dose Escalation Versus Standard in Laryngopharyngeal Cancers (INTELHOPE)

Malignant Neoplasm of Oropharynx Stage III | Malignant Neoplasm of Larynx Stage III | Malignant Neoplasm of Hypopharynx Stage III | Malignant Neoplasm of Oropharynx Stage IVa | Malignant Neoplasm of Oropharynx Stage IVb | Malignant Neoplasm of Larynx Stage IV | Malignant Neoplasm of Hypopharynx... and other conditions

India
UNC Lineberger Comprehensive Cancer Center

Completed

Functional Sparing of Salivary Glands Using MRI Sialography for Patients Undergoing Definitive Radiation Therapy for Head and Neck Cancers of the Oropharynx

Head and Neck Cancer | Oropharynx Cancer | Xerostomia Due to Radiotherapy

United States
Ohio State University Comprehensive Cancer Center
National Comprehensive Cancer Network

Completed

Ph I Vorinostat in the Treatment of Advanced Staged Oropharyngeal Squamous Cell Carcinoma

Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IV Squamous Cell Carcinoma of the Oropharynx

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Photodynamic Therapy With HPPH in Treating Patients With Squamous Cell Carcinoma of the Oral Cavity

Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Verrucous Carcinoma of the Oral Cavity | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Oropharynx | Stage I Verrucous... and other conditions

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

Human Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx | Stage IVB Squamous Cell Carcinoma of the Oropharynx

United States
University of Chicago
National Cancer Institute (NCI)

Active, not recruiting

Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer (OPTIMA)

Human Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx | Stage IVB Squamous Cell Carcinoma of the Oropharynx

United States
Lawson Health Research Institute

Active, not recruiting

A Phase II Randomized Trial for Early-stage Squamous Cell Carcinoma of the Oropharynx: Radiotherapy vs Trans-oral Robotic Surgery (ORATOR) (ORATOR)

Early-Stage Squamous Cell Carcinoma of the Oropharynx

Canada, Australia
AHS Cancer Control Alberta
Cross Cancer Institute; Tom Baker Cancer Centre

Recruiting

p16+ Oropharyngeal Cancer Radiation Optimization Trial Reducing Elective Treatment Volumes (PROTEcT) (PROTEcT)

Squamous Cell Carcinoma of the Oropharynx

Canada
Ohio State University Comprehensive Cancer Center

Completed

Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High At-Risk Appalachian Patients Oral Cancer Survivors

Tongue Cancer | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Oropharynx | Stage I Verrucous Carcinoma of the Oral Cavity | Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage II Squamous Cell Carcinoma of the Oropharynx | Stage... and other conditions

United States
Region Örebro County
Värmland County Council, Sweden; Region Stockholm; Dalarna County Council, Sweden and other collaborators

Active, not recruiting

Circulating Biomarkers in Oropharyngeal Cancers (CIRCOS)

Oropharynx Cancer | Oropharynx Squamous Cell Carcinoma | Base of the Tongue Carcinoma | Tonsillar Cancer

Sweden
Robert L. Ferris, MD, PhD
Bristol-Myers Squibb

Active, not recruiting

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

Oropharynx Squamous Cell Carcinoma | Carcinoma, Squamous Cell of Head and Neck

United States
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Swallowing, Speech and Quality of Life of Patients With Carcinoma of the Oropharynx

Squamous Cell Carcinoma of the Oropharynx

France
Region Skane

Recruiting

Monitoring and Early Response Evaluation Using HPV DNA - A Study on Patients With HPV-positive Throat Cancer (MER-HPV) (MER-HPV)

Oropharynx Squamous Cell Carcinoma

Sweden
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Treatment De-Intensification for Squamous Cell Carcinoma of the Oropharynx

Squamous Cell Carcinoma of Oropharynx

United States
University of Michigan Rogel Cancer Center
Bristol-Myers Squibb

Active, not recruiting

Radiotherapy, Carboplatin/Paclitaxel and Nivolumab for High Risk HPV-related Head and Neck Cancer

Oropharynx Squamous Cell Carcinoma

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

HPV Serum DNA Levels Predicting Outcome in p16+ Squamous Cell Head and Neck Cancer

Subjects With p16 Positive/HPV Positive Squamous Cell Carcinomas of the Oropharynx

United States
University of Virginia

Not yet recruiting

HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma (HN001)

Squamous Cell Carcinoma of the Oropharynx

United States
Royal Marsden NHS Foundation Trust
Institute of Cancer Research, United Kingdom; Oracle Cancer Trust

Recruiting

Evaluation of Tongue Base MucOsectomy & Step sErial Sectioning (MOSES)

Squamous Cell Carcinoma of the Oropharynx

United Kingdom
Joseph Califano
Johns Hopkins University; NYU Langone Health; Greater Baltimore Medical Center; San Diego Veterans Healthcare System and other collaborators

Completed

Saliva-based Detection of CD44 (Detect 44)

Squamous Cell Carcinoma of the Head and Neck | Oropharynx Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma | Squamous Cell Carcinoma of the Oropharynx

United States
ISA Pharmaceuticals
Regeneron Pharmaceuticals

Active, not recruiting

A Randomized Phase 2 Study of Cemiplimab ± ISA101b in HPV16-Positive OPC

Squamous Cell Carcinoma of the Oropharynx | HPV16 Positive

Netherlands, United States, United Kingdom, France, Belgium, Czechia, Spain, Italy, Germany, Brazil, Hungary, Mexico, Poland
ISA Pharmaceuticals
Regeneron Pharmaceuticals

Active, not recruiting

A Phase II Study of Cemiplimab and ISA101b in Patients With Recurrent/Metastatic HPV16 Positive OPC

Squamous Cell Carcinoma of the Oropharynx

United States, Israel, Belgium, Germany, Spain, United Kingdom, Italy, France, Czechia
Loren Mell, MD

Recruiting

QUantitative Assessment of Swallowing After Radiation (QUASAR) (QUASAR)

Head and Neck Cancer | Dysphagia | Oropharyngeal Dysphagia | Oropharynx Cancer | Oropharynx Squamous Cell Carcinoma

United States
Roswell Park Cancer Institute
National Institutes of Health (NIH); Biolitec Pharma Ltd.

Withdrawn

Photodynamic Therapy Using Temoporfin Before Surgery in Treating Patients With Recurrent Oral Cavity or Oropharyngeal Cancer

Tongue Cancer | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Verrucous Carcinoma of the Oral Cavity | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Oropharynx and other conditions
Mayo Clinic

Active, not recruiting

Evaluation of De-escalated Adjuvant Radiation Therapy for Human Papillomavirus (HPV)-Associated Oropharynx Cancer

Oropharynx Cancer

United States
UNICANCER

Active, not recruiting

Feasibility and Tolerance of Nivolumab Neoadjuvant Immunotherapy in High Risk HPV Driven Oropharynx Cancer (IMMUNEBOOST)

Oropharynx Cancer

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Minocycline for Reduction of Radiation Therapy Treatment-Related Symptom Burden in Oropharynx Cancer: A Randomized Study.

Oropharynx Cancer

United States
CMR Surgical Ltd
Liverpool University Hospitals NHS Foundation Trust; Sintesi Research S.r.l.

Recruiting

Prospective Clinical Study to Assess the Safety and Efficacy of Versius, in Transoral Robotic Surgery

Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma, Unknown Primary

United Kingdom
Fondation Hôpital Saint-Joseph

Not yet recruiting

Identification of Individual Histological and Blood Markers in Patients With Recurrent or Metastatic Upper Aerodigestive Tract Squamous Cell Carcinoma in Response to Immunotherapies (iMonitORL)

Squamous Cell Carcinoma of the Oropharynx

France
Rigshospitalet, Denmark
The Novo Nordic Foundation

Completed

Outpatient Ultrasound for the Diagnostic Work-up of Oropharynx Cancer

Oropharynx Cancer | Tonsil Cancer | Tonsil Hypertrophy | Tonsil Neoplasm | Tonsil Lymphoma | Base of Tongue Carcinoma | Oropharynx Neoplasm | Base of Tongue Tumor

Denmark
Thomas Hummel

Recruiting

Bitter Taste Receptors in Oropharynx Cancer

Oropharynx Cancer

Germany
University Health Network, Toronto

Completed

Study of Lymphatic Drainage Mapping in Oropharyngeal Cancers

Oropharynx Cancer

Canada
Indiana University

Recruiting

Adjuvant Treatment Deintensification After Transoral Surgery for Human Papillomavirus-Positive Squamous Cell Carcinoma

HPV Positive Oropharyngeal Squamous Cell Carcinoma | Squamous Cell Carcinoma of the Oropharynx

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

A Trial of Photodynamic Therapy With HPPH for Treatment of Dysplasia, Carcinoma in Situ and T1 Carcinoma of the Oral Cavity and/or Oropharynx

Dysplasia | Carcinoma of the Oral Cavity | Carcinoma of the Oropharynx

United States
Yonsei University

Active, not recruiting

Window of Opportunity Trial of Durvalumab (MEDI4736) or Durvalumab/Tremelimumab as Neoadjuvant Chemotherapy to Identify Immune Dynamics in Surgically Resectable Head and Neck Cancer Patients.

Larynx | Stage II-IVB Operable HNSCC Oral Cavity | Hypopharynx | Oropharynx

Korea, Republic of
University of Maryland, Baltimore

Recruiting

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL) (SAVAL)

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Oropharynx Cancer | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Oropharynx Squamous Cell Carcinoma

United States

Clinical Trials on Oropharynx

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