Clinical Trials on PAH Deficiency

Total 9345 results

United Therapeutics

Withdrawn

Dose Escalation, MTD, Safety and PK Study of a Single Dose SC Injection of TransCon PEG Treprostinil in Healthy Male Volunteers

PAH

United States
Actelion

Active, not recruiting

Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH) (A DUE)

Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)

United States, Japan, Taiwan, Turkey, Canada, China, Germany, Spain, Italy, Malaysia, Hungary, Russian Federation, Brazil, Australia, Bulgaria, Czechia, Mexico, Poland, South Africa
The Cleveland Clinic

Withdrawn

Biomarkers in Pulmonary Arterial Hypertension Treated With Nilotinib

PAH

United States
Technische Universität Dresden
GWT-TUD GmbH

Recruiting

COMPERA / COMPERA-KIDS (COMPERA)

Pulmonary Arterial Hypertension (PAH) | Pulmonary Hypertension (PH)

Germany, Belgium, Italy, Switzerland
Homology Medicines, Inc

Terminated

Safety and Efficacy of HMI-103 in Participants With Classical PKU Due to PAH Deficiency

Phenylketonuria | Phenylketonurias | PAH Deficiency

United States
Homology Medicines, Inc

Terminated

Gene Therapy Clinical Study in Adult PKU (pheNIX)

Phenylketonurias | PAH Deficiency

United States
Taipei Veterans General Hospital, Taiwan
BioMarin Pharmaceutical

Unknown

BH4 Responsiveness in PAH Deficiency PKU Patients

PAH Deficiency | Pku Phenylketonuria
The Cleveland Clinic

Completed

Pulmonary Hypertension and Imatinib

PAH

United States
United Therapeutics

Completed

Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years

PAH

United States
Homology Medicines, Inc

Enrolling by invitation

Long-Term Follow Up Study of Subjects Previously Administered HMI 102

Phenylketonuria | PAH Deficiency

United States
Focus Medical, LLC

Completed

Evaluation of the Effectiveness of the PiQo4 System for Reduction of Infra-orbital Pigmentation

POH

United States
Eximo Medical Ltd.

Completed

Safety and Effectiveness of B-Laser™ in Subjects Affected With Infrainguinal PAD

PAD

United States, Austria, Italy
W.L.Gore & Associates

Completed

Clinical Investigation of the GORE® Drug-Coated PTA Balloon Catheter (GORE® DCB Catheter) (DCB)

PAD

Germany
CARE Pharma Shanghai Ltd.

Completed

Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of a Single Ascending Dose (SAD) of CAN106 Administered Intravenously (IV) in Healthy Subjects

PNH

Singapore
Mahidol University

Unknown

The Use of Sunscreen Starting on the First Day After Ablative Fractional Skin Resurfacing

PIH

Thailand
EndoCore Lab s.r.l.
Fondazione Italiana Vascolare

Completed

SUPERa Stenting After SUBintimal Crossing of TASC C-D Femoro-popliteal Lesions in CLI Patients (SUPERSUBII)

PAD

United States, Argentina, Italy, United Kingdom
University of Vermont Medical Center
Society for Vascular Surgery Patient Safety Organization; The Medical Device...

Unknown

VISION and VQI Paclitaxel Safety Analysis (VISION-VQI)

PAD
Avera McKennan Hospital & University Health Center
Cellworks Group Inc.

Recruiting

A Survey of Physician and Molecular Tumor Board Perspectives on the Clinical Utility and Usability of Cellworks Singula™ and Ventura™ Reports in Facilitating Patient Treatment Decisions for Pan-Cancer Patients

Pan-cancer

United States
Ono Pharmaceutical Co. Ltd

Recruiting

ONO-4538 Phase II Rollover Study (ONO-4538-98)

Pan-tumor

Japan, Korea, Republic of, Taiwan
Unity Health Toronto
Ryerson University

Withdrawn

Pulse Wave Velocity Imaging in the Assessment of PAD (PWVi)

PAD | Optical Imaging
Taichung Veterans General Hospital

Completed

Clinical Parameters Predicting Unsatisfactory Cervicovaginal Cytology in Conventional Smears

Unsatisfactory Pap Smear

Taiwan
Philips Clinical & Medical Affairs Global

Recruiting

IVUS-Guided Treatment for Percutaneous Vascular Interventions (IGT-PVI)

CAD | PAD | DVT

United States
Bristol-Myers Squibb

Completed

A Study of Nivolumab Combined With Ipilimumab and Nivolumab Alone in Patients With Advanced or Metastatic Solid Tumors of High Tumor Mutational Burden (TMB-H) (CheckMate 848)

Pan Tumor

United States, Puerto Rico, Italy, Argentina, Australia, Belgium, Canada, Chile, Denmark, France, Germany, Netherlands, Poland, Romania, Singapore, Spain, United Kingdom
Washington University School of Medicine

Completed

Addressing Unmet Basic Needs to Improve Adherence Among Women With an Abnormal Pap

Colposcopy | Abnormal Pap Smear

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for the Early Diagnosis and Monitoring in Tyrosinemia Type 1 (BioTyrosin) (BioTyrosin)

Metabolic Disorders | Tyrosinosis | Hepatorenal Tyrosinemia | Fumarylacetoacetase Deficiency | Fah Deficiency

Germany, Sri Lanka, India
A.G. Huppelschoten

Unknown

Willingness to Pay for Patient-centred Care

Willingness-to-pay | Patient-centredness

Netherlands
AbbVie

Active, not recruiting

A Study to Assess Change in Disease Activity and Adverse Events of Adalimumab in Chinese Participants Requiring High Dose Corticosteroids for Active Non-Infectious Intermediate, Posterior, or Pan-Uveitis

Non-infectious Intermediate Posterior- or Pan-uveitis

China
Novartis Pharmaceuticals

Withdrawn

Study of FTY720 in Patients With Uveitis

Acute Noninfectious Posterior, Intermediate, or Pan Uveitis
EarlySense Ltd.

Withdrawn

Evaluation of EverOn™ - A Contact-Free System for Measuring Heart Rate, Respiratory Rate and Motion

Post Surgical Pat., Medical Pat., Resp. Failure, Car.Arrest, Death

United States
National Heart, Lung, and Blood Institute (NHLBI)
Zymedi, Co., Ltd.

Recruiting

Study of Intravenous ZMA001 in Healthy Subjects

Pulmonary Arterial Hypertension PAH

United States
University of Alabama, Tuscaloosa

Unknown

Improving Family Well-Being and Child School Readiness: Power PATH Dual Generation Intervention

Power PATH | Head Start as Usual

United States
Takeda

Completed

Adherence to PTH(1-84) Treatment (FP-002-IM)

Clinical Use of PTH(1-84)

Denmark
Shenzhen Aibo Medical Robot Co., LTD

Not yet recruiting

A Clinical Study for the Pan-vascular Interventional Robotic System

Percutaneous Coronary Intervention | Pan-vascular Interventional Robotic System

China
Hadassah Medical Organization

Unknown

Periodontally Accelerated Orthodontics - A Novel Technique For a Shortened Orthodontic Treatment With a Stable Result. A Clinical and Computerized Tomography Analysis

Periodontal Status of Patients Treated With PAO Tec

Israel
Mayo Clinic

Recruiting

INTERogating Cancer for Etiology, Prevention and Therapy Navigation (INTERCEPTioN)

Cancer | Cancer Gene Mutation | PAN Gene Mutation

United States
Soroka University Medical Center

Completed

Point of Care Ultrasonography Assessment During Pulmonary Hypertension Clinic (POCUSPAH)

POCUS Assessment During Ambulatory PAH Clinic

Israel
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Right Ventricular Pulmonary Vascular Interaction in Pulmonary Hypertension

Pulmonary Arterial Hypertension (PAH)
Ohio State University

Recruiting

Investigating the Clinical Impact of a Novel Adipose Allograft Matrix on Knee Fat Pad Impingement Treatment

Fat Pad Syndrome

United States
University Medicine Greifswald
OMT GmbH & Co. KG

Unknown

Observation Study With Implantable Medication Pump for Intravenous Treprostinil Therapy in Patients With Pulmonary Arterial Hypertension (LPS-II)

Pulmonary Arterial Hypertension | PAH

Germany
Complexa, Inc.
Medpace, Inc.; Allegheny Singer Research Institute (also known as Allegheny... and other collaborators

Terminated

CXA-10 Study in Subjects With Pulmonary Arterial Hypertension

PAH

United States, United Kingdom
Complexa, Inc.
Philips Healthcare; Medpace, Inc.; Allegheny Singer Research Institute (also... and other collaborators

Terminated

PRIMEx - A Study of 2 Doses of Oral CXA-10 in Pulmonary Arterial Hypertension (PAH) (PAH)

PAH

United States, United Kingdom
University of Giessen
Philipps University Marburg Medical Center

Recruiting

(RIGHT HEART III Study - Right Ventricular Hemodynamic Evaluation and Response to Treatment) (RightHeartIII)

Pulmonary Arterial Hypertension (PAH)

Germany
CARE Pharma Shanghai Ltd.

Recruiting

A Study on the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of CAN106 in Subjects With PNH

Hemolysis | PNH

China
Acceleron Pharma, Inc., a wholly-owned subsidiary...

Recruiting

A Long-term Follow-up Study of Sotatercept for PAH Treatment (MK-7962-004/A011-12) (SOTERIA)

Pulmonary Arterial Hypertension | PAH

United States, France, Germany, Spain, Sweden, Argentina, Australia, Austria, Colombia, Croatia, Denmark, Greece, Israel, Italy, Korea, Republic of, Netherlands, New Zealand, Portugal, Serbia, Taiwan, United Kingdom, Brazil, Canada, B... and more
Spruce Biosciences

Completed

Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia | CAH - Congenital Adrenal Hyperplasia | CAH - 21-Hydroxylase Deficiency

United States
Riphah International University

Not yet recruiting

Effects of UE Aerobic Exercise on Exercise Capacity and PA in Patients With Pulmonary Arterial Hypertension.

Pulmonary Arterial Hypertension (PAH)

Pakistan
Pfizer Pharmaceuticals Ltd.

Completed

a Non-interventional Study of Sildenafil in the Treatment of Pulmonary Arterial Hypertension (PAH) in Adults From China

Pulmonary Arterial Hypertension (PAH)

China
Nutrition Institute, Slovenia
European Regional Development Fund; Vizera d.o.o.; Frutarom Etol d.o.o.

Completed

ETOL-Elderly Study of the Efficiency of the Innovative Food Supplement in Elderly Adults (ETOL-Elderly)

Vitamin B 12 Deficiency | Vitamin d Deficiency | Protein Deficiency

Slovenia
Washington University School of Medicine
University of California, Davis; Universidad San Francisco de Quito; Pan American...

Completed

Cracking the Egg Potential: Improving Young Child Nutrition in Ecuador

Choline Deficiency | Vitamin B-12 Deficiency | Lipids Deficiency | Amino Acids Deficiency

Ecuador
Regeneron Pharmaceuticals

Available

Compassionate Use of Pozelimab

Paroxysmal Nocturnal Hemoglobinuria (PNH) | CD55-deficient Protein-losing Enteropathy (PLE) | CD59 Deficiency

Clinical Trials on PAH Deficiency

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in France

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations