Clinical Trials on Pancreatic Insufficiency

Total 16519 results

Nordmark Arzneimittel GmbH & Co. KG
Parexel

Completed

Efficacy and Tolerability of NM-BL in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis

Digestive System Diseases | Respiratory Tract Diseases | Lung Diseases | Cystic Fibrosis | Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Safety and Efficacy Study of 2 Pancreatic Enzymes for Treatment of Exocrine Pancreatic Insufficiency in Cystic Fibrosis.

Exocrine Pancreatic Insufficiency: Cystic Fibrosis

United Kingdom, Italy, Belgium, Bulgaria, France, Germany, Poland
Digestive Care, Inc.

Completed

Evaluation of the Safety and Efficacy of Pancrecarb® MS-16 in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Efficacy and Safety of Ultrase® MT20 in Improving the Coefficient of Fat Absorption (CFA) in Children With Cystic Fibrosis (CF) and Pancreatic Insufficiency (PI)

Cystic Fibrosis | Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Use of Ultrase® MT12 in Young Cystic Fibrosis Children (CF)

Cystic Fibrosis | Pancreatic Insufficiency

United States
Corporacion Parc Tauli

Completed

Prevalence of Exocrine Pancreatic Insufficiency in Patients With Decompensated Cirrhosis ((EPIIHC))

Exocrine Pancreatic Insufficiency

Spain
Abbott
AbbVie; Parexel; Datamap; LKF Laboratorium für Klinische Forschung GmbH; Analytical... and other collaborators

Completed

Efficacy and Safety Study of Creon IR in Subjects With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Exocrine Pancreatic Insufficiency in Subjects With Cystic Fibrosis

Spain, Czech Republic, Hungary, Poland
National Institute of Diabetes and Digestive and...
Cystic Fibrosis Foundation

Completed

Prediction by Ultrasound of the Risk of Hepatic Cirrhosis in Cystic Fibrosis (PUSH)

Cystic Fibrosis | Pancreatic Insufficiency

United States, Canada
First Wave Bio, Inc.

Completed

OPTION 2: A Trial to Assess the Safety and Efficacy of MS1819 in Enteric Capsules in Patients With Cystic Fibrosis

Cystic Fibrosis (CF) | Exocrine Pancreatic Insufficiency (EPI)

United States, Poland
First Wave Bio, Inc.

Completed

OPTION: A Trial to Assess the Safety & Efficacy of MS1819 in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis (OPTION)

Cystic Fibrosis (CF) | Exocrine Pancreatic Insufficiency (EPI)

United States, Poland
AbbVie

Completed

Effect of CREON on Exocrine Pancreatic Insufficiency (EPI) Symptoms (CisCP)

Chronic Pancreatitis

United States
Baylor College of Medicine

Completed

Detection of Exocrine Pancreatic Insufficiency in Patients With Diarrhea and Bloating

Abdominal Pain | Diarrhea | Exocrine Pancreatic Insufficiency

United States
Moscow Clinical Scientific Center
IRCCS San Raffaele; Istanbul University; University of Belgrade; University of... and other collaborators

Unknown

Pancreatic Cancer Malnutrition and Pancreatic Exocrine Insufficiency in the Course of Chemotherapy in Unresectable Pancreatic Cancer (PAC-MAIN)

Pancreatic Cancer | Malnutrition | Chemotherapy | Exocrine Pancreatic Insufficiency | Metastatic Pancreatic Cancer | Locally Advanced Malignant Neoplasm

Turkey, Italy, Romania, Russian Federation, Serbia, Spain
National Institute of Diabetes and Digestive and...
Cystic Fibrosis Foundation

Completed

MRI to Characterize and Predict CF Liver Disease in PUSH Cohort

Pancreatic Insufficiency | Cystic Fibrosis Liver Disease

United States
Marmara University
Yeditepe University

Completed

Hypoglycemia and Glucagon Response in CF

Hypoglycemia | Cystic Fibrosis | Pancreatic Insufficiency | Glucagon Deficiency

Turkey
Gangnam Severance Hospital

Active, not recruiting

New Predictive Marker for Pancreatic Cancer Using CA19-9 and Fecal Elastase

Paancreatic Cancer

Korea, Republic of
University of Pennsylvania
Children's Hospital of Philadelphia

Recruiting

Beta-cell Response to Incretin Hormones in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
University of Pennsylvania
Children's Hospital of Philadelphia

Completed

Effect of Chronic Incretin-based Therapy in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
Anagram Therapeutics, Inc.

Recruiting

Phase 1 Study to Assess Safety and Efficacy of ANG003

Exocrine Pancreatic Insufficiency

United States
Alcresta Therapeutics, Inc.

Completed

Safety, Tolerability and Fat Absorption Using Enteral Feeding In-line Enzyme Cartridge (Relizorb)

Exocrine Pancreatic Insufficiency

United States
Andrew Hendifar, MD
VIVUS LLC

Recruiting

Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic Insufficiency (PANCAX-3)

Pancreatic Adenocarcinoma

United States
Changhai Hospital

Completed

AI Evaluation of Pancreatic Exocrine Insufficiency in CP Patients

Chronic Pancreatitis | Machine Learning | Exocrine Pancreatic Insufficiency | Deep Learning

China
Children's Hospital of Philadelphia
Solvay Pharmaceuticals

Completed

Malabsorption Blood Test:Toward a Novel Approach to Quantify Steatorrhea (MBT)

Cystic Fibrosis | Pancreatic Insufficiency

United States
Mylan Inc.

Completed

Special Investigation of LipaCreon on Long-term Use in Patients With Pancreatic Exocrine Insufficiency

Digestive System Diseases | Pancreatic Diseases | Exocrine Pancreatic Insufficiency

Japan
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Enzyme Activity and Safety of Pancrelipase in Patients With Severe Exocrine Pancreatic Insufficiency (EPI)

Steatorrhea | Pancreatitis | Pancreatitis, Chronic | Exocrine Pancreatic Insufficiency
Forest Laboratories
University of Florida

Terminated

A Study of EUR-1066 in Subjects With Chronic Pancreatitis, Exocrine Pancreatic Insufficiency and Chronic Abdominal Pain (EUR-1066)

Chronic Pancreatitis

United States
AstraZeneca

Completed

A Study to Investigate How Common Pancreatic Exocrine Insufficiency (PEI) is in Patients With Type 2 Diabetes and Also to Investigate the Uptake of a Single Dose of EPANOVA® or OMACOR® in Patients With Different Degrees of PEI (PRECISE)

Diabetes Mellitus, Type 2 | Exocrine Pancreatic Insufficiency

Sweden, Poland, Latvia, Denmark, Hungary, Slovakia
Changhai Hospital

Recruiting

Endotherapy for Painless Chronic Pancreatitis (EACH)

Abdominal Pain | Pancreatitis, Chronic | Exocrine Pancreatic Insufficiency | Cholangiopancreatography, Endoscopic Retrograde

China
Forest Laboratories

Completed

Safety and Efficacy Study of Viokase® 16 for the Correction of Steatorrhea

Chronic Pancreatitis | Exocrine Pancreatic Insufficiency | Pancreatectomy

Canada, United States, Poland, Slovakia
University of Pennsylvania
Children's Hospital of Philadelphia

Recruiting

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

Diabetes | Cystic Fibrosis | Pancreatic Insufficiency | Abnormal Glucose Tolerance

United States
Digestive Care, Inc.

Withdrawn

Open Label Safety Study of DCI-1020 in Pediatric Cystic Fibrosis (CF) Patients

Digestive System Diseases | Cystic Fibrosis | Exocrine Pancreatic Insufficiency | Pancreatic Disease

United States
Orlando Health, Inc.
ChiRhoClin, Inc.

Terminated

Recurrent Abdominal Pain and Exocrine Pancreatic Insufficiency

Irritable Bowel Syndrome | Abdominal Pain

United States
Arbelaez, Ana Maria
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Novo... and other collaborators

Completed

Pilot and Feasibility Study for the Treatment of Pre-diabetes in Patients With Cystic Fibrosis

Pancreatic Insufficiency | Cystic Fibrosis Related Diabetes

United States
Anthera Pharmaceuticals

Completed

SOLUTION: Study of Oral Liprotamase Unit-Matched Therapy Of Non-Porcine Origin in Patients With Cystic Fibrosis

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States, Hungary, Israel, Poland, Spain, Canada, Czechia
Anthera Pharmaceuticals

Completed

Liprotamase Efficacy Trial in Patients With Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency (DIGEST)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
First Wave BioPharma, Inc.

Completed

Study to Assess an Enteric Microgranule Formulation of Adrulipase in Patients With Cystic Fibrosis (SPAN)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
AbbVie

Completed

A Study to Compare US Marketed Creon Manufactured With a Modernized Process at an Alternate Manufacturing Site and Manufactured With the Approved Manufacturing Process at an Alternate Active Pharmaceutical Ingredient Site, in Participants With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis

Cystic Fibrosis

United States
Forest Laboratories

Completed

PR-018: An Open-Label, Safety Extension of Study PR-011

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Study of Pancreatic Enzyme Product in Pediatric Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Study to Evaluate the Safety and Efficacy of EUR-1008 (APT-1008) Pancreatic Enzyme Product in Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
GlycosBio, Inc.
Baylor College of Medicine

Completed

Assessment of a PERT-free Nutritional Therapeutic Delivery System for Cystic Fibrosis

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Anthera Pharmaceuticals

Completed

EASY: Extended Access to Sollpura Over Years

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States, Hungary, Israel, Poland, Spain, Czechia
Anthera Pharmaceuticals

Unknown

RESULT: Reliable, Emergent Solution Using Liprotamase Treatment

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States, Hungary, Israel, Lithuania, Poland, Spain, United Kingdom
Anthera Pharmaceuticals

Completed

Open-Label Phase III Long-Term Safety Trial of Liprotamase (DIGEST)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Forest Laboratories

Completed

A Study to Evaluate the Mode of Administration and Safety of EUR-1008 (APT-1008) in Infants 1 to 12 Months of Age

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Mylan Inc.

Completed

Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Digestive System Diseases | Pancreatic Diseases | Cystic Fibrosis | Exocrine Pancreatic Insufficiency

Japan
Anthera Pharmaceuticals

Completed

SIMPLICITY: Studying Impacts on Malabsorption With Liprotamase in Cystic Fibrosis (SIMPLICITY)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Seattle Children's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Cystic...

Completed

Baby Observational and Nutritional Study (BONUS)

Cystic Fibrosis | Growth Failure | Exocrine Pancreatic Insufficiency

United States
Hopital Foch

Completed

Measurement of Lung Water by Transpulmonary Thermodilution in Lung Transplanted Patients (PICCO-LungT)

Pulmonary Insufficiency | Mucoviscidosis

France
Forest Laboratories

Completed

Safety and Efficacy Study of ULTRASE® MT20 in Participants With Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (PI)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States

Clinical Trials on Pancreatic Insufficiency

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