Clinical Trials on Partial Onset Epilepsy

Total 6919 results

Atlantic University
A.T. Still University of Health Sciences

Completed

Thermographic Examination of Skin Temperatures in Individuals With Focal Onset Epilepsy

Partial Epilepsy | Focal Onset Epilepsy

United States
Eisai Inc.

Completed

A Study to Investigate the Potential Pharmacokinetic Interaction of Perampanel With Oral Contraceptives in Healthy Female Subjects

Partial Onset Epilepsy

United Kingdom
Eisai Inc.

Completed

A Study to Demonstrate Bioequivalence Between 6 x 2 mg Tablets of Perampanel and a Single 12 mg Tablet of Perampanel in Healthy Subjects

Partial Onset Epilepsy

United Kingdom
UCB BIOSCIENCES, Inc.

Completed

Study to Assess the Long-term Safety of Oral Lacosamide in Subjects With Partial-onset Seizures

Partial Epilepsies | Partial Onset Seizures

United States
UCB BIOSCIENCES, Inc.

Completed

Safety of Intravenous Lacosamide Dose Followed by Twice Daily Oral Lacosamide in Subjects With Partial-onset Seizures

Partial Epilepsies | Partial Onset Seizures

United States
Sunovion

Completed

Safety and Efficacy of Eslicarbazepine Acetate Monotherapy in Subjects With Partial Epilepsy Not Well Controlled by Current Antiepileptic Drugs

Epilepsy With Simple or Complex Partial Onset Seizures

United States, Canada
UCB BIOSCIENCES, Inc.

Completed

Efficacy and Safety of Lacosamide as Adjunctive Therapy in Subjects ≥1 Month to <4 Years With Partial-onset Seizures

Epilepsy With Partial-onset Seizures

United States, Argentina, Brazil, Bulgaria, China, Croatia, Czechia, France, Georgia, Greece, Hungary, Israel, Italy, Korea, Republic of, Mexico, Moldova, Republic of, Philippines, Poland, Portugal, Romania, Russian Federation, Se... and more
Eisai Inc.

Completed

Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Study)

Epilepsy; Paediatric Partial Onset Seizures

Belgium, France, Italy, Spain, Estonia, Hungary, Poland, Ukraine, Latvia
İpek Dokurel

Active, not recruiting

Does Levetiracetam and Carbamazepine Impact the Autonomic Activity of Children With Self-limiting Focal Epilepsy? (levcbz)

Epilepsy; Syndrome, Seizures of Localized Onset

Turkey
Rapport Therapeutics Inc.

Not yet recruiting

Study Evaluating the Safety and Efficacy of RAP-219 in Adult Participants With Refractory Focal Epilepsy

Focal Onset Seizures
Eisai Limited

Completed

A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalization or With Primary Generalized Tonic-Clonic Seizures Associated With Idiopathic Generalized Epilepsy

Idiopathic Generalized Epilepsy | Partial Onset Seizures | Generalised Tonic-Clonic Seizures

France, Spain, Italy, Denmark, Germany, Portugal, Russian Federation
UCB Japan Co. Ltd.

Completed

An Open Label Study of Levetiracetam Monotherapy in Patients With Newly Diagnosed Focal Epilepsy

Epilepsy | Partial Onset Seizures

Japan
UCB Japan Co. Ltd.

Completed

An Open Label Study of L059 Intravenous (IV) in Japanese Epilepsy Subjects With Partial Onset Seizures

Epilepsy | Partial Onset Seizures

Japan
Eisai Co., Ltd.

Completed

A Study to Evaluate the Safety and Efficacy of Fycompa® (Perampanel) as Add-on Therapy in Participants With Epilepsy

Epilepsy | Partial-onset Seizures
UCB Pharma SA
UCB Japan Co. Ltd.

Completed

A Trial to Evaluate the Efficacy and Safety of Adjunctive Therapy With Lacosamide in Adults With Partial-Onset Seizures

Epilepsy | Partial Onset Seizures

China, Japan
UCB Japan Co. Ltd.
Parexel

Completed

Open-label Study to Evaluate the Safety and Tolerability of iv Lacosamide in Japanese Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

Japan
UCB Pharma SA
UCB Japan Co. Ltd.

Completed

Study to Evaluate the Safety, Tolerability, and Efficacy of Long-term Adjunctive Therapy With Lacosamide in Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

China, Japan
UCB Japan Co. Ltd.

Completed

A Trial to Evaluate the Long Term Safety and Tolerability of Lacosamide Taken as Monotherapy in Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

Japan
Eisai Pharmaceuticals India Pvt. Ltd

Completed

A Study to Assess Safety and Efficacy of Perampanel in Indian Participants as an Adjunctive Treatment in Partial Onset Seizures With or Without Secondary Generalized Seizures in Participants With Epilepsy Aged 12 Years or Older

Epilepsy | Partial Onset Seizures

India
University Hospital Schleswig-Holstein

Completed

Lacosamid-i.v.-Register (LCM)

Epilepsy With Partial Onset Seizures With or Without Secondary Generalization

Germany
SK Life Science, Inc.

Completed

An Open-Label Extension Study of the Safety and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures

Epilepsy, Complex Partial | Epilepsy, Partial, Motor | Epilepsy, Simple Partial | Focal Motor Epilepsy
SK Life Science, Inc.

Completed

A Study of the Effectiveness, Safety, and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures.

Epilepsy, Complex Partial | Epilepsy, Partial, Motor | Epilepsy, Simple Partial | Focal Motor Epilepsy
Eisai Inc.

Completed

Study to Investigate Dosage, Efficacy, and Safety of Perampanel Given as Monotherapy in Patients With Epilepsy

Epilepsy | Primary Generalized Tonic-Clonic Seizures | Partial-Onset Seizures
Eisai Inc.

Recruiting

A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy

Partial-onset Seizures | Pediatric Epileptic Syndrome

United States, Spain, France, Belgium, Czechia, Denmark, Germany
Neurocrine Biosciences

Terminated

Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Australia, Belgium, Czechia, France, Hungary, Italy
Neurocrine Biosciences

Completed

A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Belgium, Czechia, France, Italy, Australia, Hungary, United Kingdom
University Hospital, Lille

Unknown

National Study on the Interest of EEG-fMRI in the Presurgical Evaluation of Partial Epilepsies Drug (ENERGY)

Focal Epilepsy | Epilepsy Intractable

France
Bial - Portela C S.A.

Completed

Efficacy and Safety of Eslicarbazepine Acetate as Adjunctive Therapy for Refractory Partial Seizures

Refractory Partial Epilepsy

Portugal
Northeast Regional Epilepsy Group
Pfizer

Terminated

Effect on Anxiety in Partial Epilepsy Patients Treated With Pregabalin

Epilepsy, Complex Partial

United States
Xuanwu Hospital, Beijing
Peking University; Beijing Tiantan Hospital; Qilu Hospital of Shandong University and other collaborators

Not yet recruiting

Subthalamic Nucleus Electrical Stimulation for Drug-resistant Focal Motor Epilepsy (STEM)

Epilepsy, Drug Resistant

China
Emory University
Patient-Centered Outcomes Research Institute

Terminated

Cognitive AED Outcomes in Pediatric Localization Related Epilepsy (COPE) (COPE)

Epilepsy, Partial | Epilepsy, Localization Related

United States
The Hospital for Sick Children

Completed

Improving Lesion Detection in Children With Magnetic Resonance Imaging (MRI)-Negative Partial Epilepsy Using Diffusion Tensor Imaging

Partial Epilepsy | Localization-related Epilepsy

Canada
Hospices Civils de Lyon

Completed

National Network for the Study of Predictors and Prevention of Sudden Unexpected Death in Drug-resistant Partial Epilepsies (REPOMSE)

Drug-resistant Partial Epilepsy

France
Bial - Portela C S.A.

Completed

Eslicarbazepine Acetate (BIA 2 093) as Therapy for Refractory Partial Seizures in Children

Partial Epilepsy in Children and Adolescents

United Kingdom, Spain, Serbia, Italy, Austria, Bosnia and Herzegovina, Croatia, Czechia, France, Germany, Hungary, Malaysia, Moldova, Republic of, Philippines, Poland, Portugal, Romania, Russian Federation, Slovakia, Taiwan, Ukr...
Rennes University Hospital

Completed

Effects of Transcranial Direct Current Stimulation (TDCS) in Drug-resistant Partial Epilepsy (BRAINSTIM)

Epilepsy

France
GlaxoSmithKline

Withdrawn

Pharmacokinetic Study of Retigabine Extended Release (XR) Formulation in Healthy Adult Japanese and Caucasian Subjects

Epilepsy, Partial

Japan
Supernus Pharmaceuticals, Inc.

Completed

Safety and Tolerability of OXC XR as Adjunctive Therapy in Subjects With Refractory Partial Epilepsy

Partial Epilepsy

United States, Poland, Bulgaria, Romania, Canada, Russian Federation, Mexico, Croatia
Central Hospital, Nancy, France
Institut National de la Santé Et de la Recherche Médicale, France; CHU de Reims and other collaborators

Completed

Localizing the Epileptogenic Zone With High Resolution Electroencephalography (EEG-HR)

Partial Epilepsy

France
Eisai Inc.

Completed

A Double-blind Study to Compare the Efficacy and Safety of Zonisamide and Carbamazepine as Monotherapy, in Newly Diagnosed Partial Epilepsy

Epilepsy

Australia, France, Poland, Germany, Spain, India, Serbia, Greece, Korea, Republic of, Russian Federation, Taiwan, Hungary, Italy, Sweden, Denmark, Slovakia, United Kingdom, South Africa
Mayo Clinic

Completed

Pilot Study to Evaluate MR-guided Laser Ablation of Focal Lesions in Patients With Medically Refractory Partial Epilepsy

Epilepsy

United States
Cyberonics, Inc.

Terminated

Study Comparing Best Medical Practice With or Without VNS Therapy in Pharmacoresistant Partial Epilepsy Patients

Epilepsy | Partial Epilepsy

Canada, Spain, Belgium, France, Germany, Italy, Netherlands, Norway, Sweden, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-765 in Subjects With Treatment-resistant Partial Epilepsy

Partial Epilepsy

United States
Vertex Pharmaceuticals Incorporated

Terminated

A Study to Evaluate the Efficacy and Safety of VX-765 in Subjects With Treatment-Resistant Partial Epilepsy

Epilepsy

United States, Germany
Bial - Portela C S.A.

Completed

Effect of Repeat Administration of Eslicarbazepine Acetate on the Pharmacokinetics of a Combined Oral Contraceptive

Partial Epilepsy

Portugal
GlaxoSmithKline

Completed

Systematic Review: Retigabine for Adjunctive Therapy in Partial Epilepsy

Epilepsy
GlaxoSmithKline

Completed

An Observational Study to Assess the Burden of Drug-resistant Partial Epilepsy in Italy

Epilepsy, Partial
University of Minnesota

Completed

Neural Correlates of Cognition and Mood

Epilepsy, Complex Partial

United States
Supernus Pharmaceuticals, Inc.
Melbourne Health

Completed

Bioavailability, Safety, and Tolerability of BIS-001 ER

Epilepsy, Complex Partial

Australia
National Institute of Neurological Disorders and...

Recruiting

Surgery as a Treatment for Medically Intractable Epilepsy

Epilepsy | Epilepsy, Temporal Lobe | Partial Epilepsy

United States
University Hospital, Toulouse

Recruiting

Intracerebral Electrical Stimulation and the Optimisation of Presurgical Planning in Drug-refractory Partial Epilepsy (StiMiC)

Epilepsy

France

Clinical Trials on Partial Onset Epilepsy

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