Clinical Trials on Pharmacodynamics of ASP8232

Total 26355 results

Astellas Pharma Europe B.V.

Completed

A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of ASP8232 in Subjects With Renal Impairment and in Type 2 Diabetes Mellitus Subjects With Chronic Kidney Disease

Healthy Subjects | Type 2 Diabetes Mellitus (T2DM) | Chronic Kidney Disease (CKD) | Pharmacokinetics of ASP8232 | Pharmacodynamics of ASP8232

Bulgaria, Moldova, Republic of, Romania
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effects of Single Ascending Doses (SAD) of ASP8477, the Effect That Food Has on the Drug, and the Interaction Between ASP8477 and Omeprazole in Healthy Postmenopausal Females and Healthy Young Vasectomized Males

Pharmacokinetics of ASP8477 | Pharmacodynamics of ASP8477

France, Belgium
Astellas Pharma Inc

Completed

A Study in Healthy Young Men to Look at What Drives the Cardiovascular Effects After Dosing With Mirabegron.

Healthy Volunteers | Pharmacodynamics of Mirabegron

France
Astellas Pharma Europe B.V.

Completed

A Study to Investigate the Appearance and Disappearance of ASP3652 in Blood and Spinal Fluid in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of ASP3652 | Pharmacodynamics of ASP3652

United Kingdom
Astellas Pharma Global Development, Inc.
Kyowa Kirin Co., Ltd.

Completed

Bioavailability of ASKP1240 in Healthy Subjects After Intravenous and Subcutaneous Administration of ASKP1240

Healthy Volunteers | Pharmacokinetics of ASKP1240 | Pharmacodynamics of ASKP1240

United States
Seoul National University Hospital

Completed

Clinical Trial to Evaluate the Influence of Genotype on the Pharmacokinetics/Pharmacodynamics of Clopidogrel

Influence of Genotype of Drug Metabolizing Enzyme or Transporter on the Pharmacokinetics/Pharmacodynamics of Clopidogrel | Influence of Aspirin on the Pharmacokinetics/Pharmacodynamics of Clopidogrel

Korea, Republic of
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability and Effects of Single and Multiple Ascending Doses of ASP1707 in Healthy Male and Pre-menopausal Female Subjects, Including a Comparison of the Effects Under Fasted and Fed Conditions in Healthy Young Male Subjects

Pharmacokinetics of ASP1707 | Pharmacodynamics of ASP1707

France
Astellas Pharma Europe B.V.

Terminated

A Study to Assess the Safety and Tolerability, Including Gastrointestinal Safety, Pharmacokinetics and Pharmacodynamics of ASP7657 in Caucasian Healthy Male and Female Subjects

Healthy Subjects | Pharmacokinetics of ASP7657 | Pharmacodynamics of ASP7657

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability, and Effects in and on the Body of Healthy Young and Elderly Male and Female Subjects of Ascending Multiple Oral Doses of ASP3652

Healthy Subjects | Pharmacokinetics of ASP3652 | Pharmacodynamics of ASP3652

Netherlands
Astellas Pharma Inc

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K

Healthy Subjects | Pharmacodynamics | Pharmacokinetics of ASP015K

United States
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Race on How a Single Dose of ASP3652 is Taken up, Metabolized and Distributed Through the Bodies of Young, Healthy Male and Female Subjects, and Its Safety and Tolerability

Healthy Subjects | Pharmacokinetics | Pharmacodynamics | Effect of Race

United Kingdom
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Warfarin in Healthy Male Subjects

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of S- and R-warfarin | Pharmacodynamics of Warfarin

United States
Transdermal Delivery Solutions Corp
Langford Research Institute, Inc.

Completed

Transdermal Insulin Response In Healthy Volunteers

Pharmacodynamic Response to Small Doses of Insulin

United States
Turku University Hospital

Completed

Effects of Posaconazole and Voriconazole on the Pharmacokinetics and Pharmacodynamics of Sublingual Buprenorphine (PosaBupre)

Pharmacokinetics and Pharmacodynamics of Sublingual Buprenorphine

Finland
Lee's Pharmaceutical Limited

Completed

A Study to Evaluate the Safety and Tolerability of Tecarfarin in Healthy Chinese Volunteers

Pharmacokinetic and Pharmacodynamic Profile of Tecarfarin

Hong Kong
CONRAD
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Coital Pharmacokinetics/Pharmacodynamics (PK/PD) of Tenofovir Gel

Pharmacokinetics of 1% Tenofovir Gel Following Coitus | Pharmacodynamics of 1% Tenofovir Gel Following Coitus

United States
Vanda Pharmaceuticals

Completed

Evaluation of the Pharmacodynamic and Pharmacokinetic Interactions of Tasimelteon and Ethanol

Pharmacodyamics and Pharmacokinetics of Tasimelteon Alone and in Combination With Ethanol

Canada
Khon Kaen University

Completed

Comparative Pharmacodynamics and Pharmacokinetics Study of Generic and Reference Clopidogrel Products

Pharmacodynamics

Thailand
Radboud University Medical Center

Completed

Eplerenone and Extracellular Adenosine Formation (eplerenone01)

Pharmacodynamics

Netherlands
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Phase I Study in Young Healthy Women to Investigate the Effects of Laquinimod on Standard Oral Contraceptive When Both Treatments Are Given Together

Pharmacokinetics | Pharmacodynamics

Germany
Merckle GmbH

Completed

PK, PD, Safety and Tolerability of Lipegfilgrastim in Healthy Japanese and Caucasian Participants

Pharmacokinetics | Pharmacodynamics

United Kingdom
AstraZeneca

Completed

To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ascending Doses of Inhaled AZD7594

Pharmacokinetics | Safety | Pharmacodynamics of AZD7594

United Kingdom
INSYS Therapeutics Inc

Completed

Fentanyl Sublingual Spray and Fentanyl Citrate Intravenous (IV) in Opioid Naive Subjects

Pharmacokinetics and Pharmacodynamics

United States
Taipei Veterans General Hospital, Taiwan

Completed

Modeling and Application of Triple Drug Response Surface Models

Pharmacodynamics | Drug Interactions

Taiwan
AstraZeneca

Completed

A Study to Assess the Pharmacodynamic Effect of Single Doses of AZD9977 in Healthy Male Subjects

Healthy Subjects | Pharmacodynamics

United Kingdom
Takeda

Completed

Pharmacokinetics and Pharmacodynamics Study of Alogliptin in Healthy Korean Participants

Pharmacokinetics and Pharmacodynamics

Korea, Republic of
Dong-A University

Completed

Clopidogrel And Ticagrelor in Healthy Subjects

Pharmacodynamics

Korea, Republic of
Bayer

Completed

Pharmacodynamic Characterization of Dienogest

Pharmacodynamics

Netherlands
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Pharmacodynamic Biomarkers to Support Biosimilar Development: Interferon Beta-1A Products

Healthy Subjects | Pharmacokinetics | Pharmacodynamics

United States
Basking Biosciences, Inc.

Completed

Study of DTRI-031 in Healthy Volunteers

Healthy Volunteers | Pharmacokinetics | Pharmacodynamics

Australia
Takeda

Terminated

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MLN3126 in Healthy Japanese and Non-Japanese Participants

Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

United States
Il-Yang Pharm. Co., Ltd.

Completed

Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety

Healthy | Pharmacokinetics | Pharmacodynamics | Ilaprazole

Canada
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206

Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

Netherlands
Ospedale Regionale di Locarno

Completed

ESAs, Reticulocyte Dynamic and Hemoglobin Variability

Erythropoiesis Stimulating Agent Pharmacodynamics

Switzerland
Opiant Pharmaceuticals Inc

Completed

Pharmacodynamic Evaluation of Intranasal Nalmefene

Pharmacodynamic

United States
AstraZeneca

Withdrawn

A Drug-Drug Interaction Study Between AZD9668 and Warfarin to Study the Effect of AZD9668 on the Metabolism and Effect of Warfarin

Pharmacokinetics | Pharmacodynamics

Sweden
Turku University Hospital

Completed

Effect of Itraconazole and Ticlopidine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol

Pharmacokinetics | Pharmacodynamics

Finland
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Oral Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-281959 / ACT-246475 in Healthy Male Subjects

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

France
HK inno.N Corporation

Unknown

A Phase 1 Study of Tegoprazan on Healthy Male Volunteers

Pharmacokinetics | Pharmacodynamics | Healthy Male Volunteers

Korea, Republic of
Stanford University

Completed

PK/PD Modeling of Magnesium in the Mother and Neonate

Magnesium Sulfate Pharmacokinetics and Pharmacodynamics

United States
Guangzhou General Hospital of Guangzhou Military...

Completed

Pharmacodynamic Interactions of Propofol and Dexmedetomidine on Intravenous Anesthesia (PIPDIA)

Pharmacodynamic Interaction

China
Altasciences Company Inc.

Completed

Single Ascending Doses of Kratom in Healthy Nondependent Adults With Opioid Experience

Pharmacokinetics | Pharmacodynamics | Safety

United States
Cui Yimin

Unknown

Impact of Biomarkers on Pharmacokinetics and Pharmacodynamics of Ticagrelor

Pharmacokinetics | Pharmacodynamics | Pharmacogenomics | Accurate Medication | Ticagrelor

China
AstraZeneca

Completed

Study to Assess the Pharmacodynamics/Pharmacokinetics After Repeated Dosing of D961H 10 mg and Omeprazole 10 mg in Japanese Healthy Male Subjects

Pharmacodynamics Study

Japan
University of California, San Francisco

Completed

Study of the Ability of Betaine Hydrochloride to Increase Stomach Acid in Healthy Volunteers

Pharmacodynamic

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Pharmacodynamic Biomarkers to Support Biosimilar Development: PCSK9 Inhibitors

Healthy Subjects | Pharmacokinetics | Pharmacodynamics

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Pharmacodynamic Biomarkers to Support Biosimilar Development: Interleukin-5 Antagonists

Healthy Subjects | Pharmacokinetics | Pharmacodynamics

United States
HK inno.N Corporation

Completed

A Study to Evaluate Safety, Tolerability, and PD of Tegoprazan on Healthy Male Volunteers

Pharmacodynamics | Healthy Male Volunteers

Korea, Republic of
Chinese Medical Association

Unknown

Pharmacodynamics and Pharmacokinetics of Dexmedetomidine in Pediatric

Pharmacokinetics | Dexmedetomidine | Pharmacodynamics | Pediatrics

China
Geropharm

Recruiting

Double-blind, Randomized Comparative Cross-sectional Study of Pharmacodynamics and Pharmacokinetics of Drugs GP40141

Pharmacokinetics | Pharmacodynamics | Bioequivalence

Russian Federation

Clinical Trials on Pharmacodynamics of ASP8232

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