Clinical Trials on Progressive Scleroderma

Total 1974 results

W. Leroy Griffing

Recruiting

A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients

Systemic Sclerosis | Scleroderma, Systemic | Scleroderma, Diffuse | Diffuse Cutaneous Systemic Sclerosis | Interstitial Lung Disease | Scleroderma | Systemic Sclerosis, Diffuse | Diffuse Systemic Sclerosis | Pulmonary Fibrosis Interstitial | Diffuse Scleroderma | Diffuse Cutaneous Scleroderma | Progressive Systemic... and other conditions

United States
University Hospital Tuebingen

Active, not recruiting

Autologous Stem Cell Transplantation for Progressive Systemic Sclerosis (AST-MOMA)

Scleroderma | Autologous Stem Cell Transplantation | Cardiac Involvement

Germany
University of Pecs

Recruiting

Screening Patients With Diabetes Mellitus for the Presence of Skin Disorder of Scleredema

Diabetes Mellitus | Diabetes Complications | Scleroderma-Like Changes | Scleredema Adultorum

Hungary
Eye Hospital Pristina Kosovo

Enrolling by invitation

Human Fresh Corneal Lenticule Implantation Criteria in Progressive Corneal Disease Using Relex-Smile (Relex-Smile)

Progressive Disease of Corneae

Kosovo
Cumberland Pharmaceuticals

Recruiting

Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension

Pathologic Processes | Skin Diseases | Autoimmune Diseases | Connective Tissue Diseases | Scleroderma, Systemic | Scleroderma, Diffuse | Scleroderma, Limited | Sclerosis, Progressive Systemic

United States, India
University of Texas Southwestern Medical Center

Recruiting

Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository (MAC)

Scleroderma, Localized | Morphea | Frontal Linear Scleroderma en Coup de Sabre | Scleroderma, Circumscribed | Scleroderma, Linear

United States
Northwestern University

Completed

Cyclophosphamide and rATG With Hematopoietic Stem Cell Support in Systemic Scleroderma

SYSTEMIC SCLERODERMA

United States
Ferrer Internacional S.A.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of FNP-223 to Slow Progression of Progressive Supranuclear Palsy (PSP)

Progressive Supranuclear Palsy
Gilead Sciences

Completed

A Non-Interventional Pilot Study Assessing Whether Lysyl Oxidase-like 2 (LOXL2) is Present in Subjects With Scleroderma

Diffuse Scleroderma | Limited Scleroderma

Australia
Mastelli S.r.l
Sintesi Research Srl

Terminated

Efficacy and Safety of PLACENTEX ® i.m. in Patients With Scleroderma Diseases

Scleroderma Disease

Italy
AvenCell Europe GmbH
PHARMALOG Institut für klinische Forschung GmbH

Terminated

Dose-escalating Trial With UniCAR02-T Cells and PSMA Target Module (TMpPSMA) in Patients With Progressive Disease After Standard Systemic Therapy in Cancers With Positive PSMA Marker

Prostate Cancer

Germany
Lawson Health Research Institute
Novartis Pharmaceuticals

Terminated

Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma

Scleroderma

Canada
Biocad

Recruiting

Clinical Study of Divozilimab in Patients With Systemic Scleroderma (LIBERIUS)

Systemic Scleroderma

Russian Federation
Rennes University Hospital

Completed

Clinical and Paraclinical Characteristics of the Systemic Scleroderma Cohort According to the Criteria ACR 2013 and the History of Professional Exposure or of Agricultural Environment (PRESSY)

Systemic Scleroderma

France
Castle Creek Biosciences, LLC.

Terminated

A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)

Scleroderma, Localized | Morphea | Scleroderma

United States
Assistance Publique - Hôpitaux de Paris
Actelion

Completed

Effect of Bosentan in Scleroderma Renal Crisis (ScS-REINBO)

Scleroderma Renal Crisis

France
Hospices Civils de Lyon

Recruiting

Management of Progressive Disease in Idiopathic Pulmonary Fibrosis (PROGRESSION)

Progressive Idiopathic Pulmonary Fibrosis

France
University Hospital, Lille

Recruiting

Trichoscopy and Systemic Scleroderma (TRICHLOSCLERO)

Scleroderma, Systemic

France
University of Cologne

Recruiting

Clinical Trial to Evaluate Efficacy and Safety of Dupilumab in Localized Scleroderma (DupiMorph)

Localized Scleroderma

Germany
Cairo University

Unknown

Fractional Carbon Dioxide Laser Versus UVA 1 in Treatment of Localized Scleroderma

Localized Scleroderma

Egypt
Assistance Publique - Hôpitaux de Paris

Completed

Treatment of Refractory Sever Systemic Scleroderma by Injection of Allogeneic Mesenchymal Stem Cells (MSC)

SYSTEMIC SCLERODERMA | ALLOGENEIC MESENCHYMAL STEM CELLS | ADULT

France
University of Texas Southwestern Medical Center

Completed

Treatment Study Comparing UVA-1 Phototherapy Versus Placebo Treatment for Morphea

Scleroderma, Localized | Morphea | Scleroderma, Circumscribed

United States
University of Utah

Enrolling by invitation

UVA-1 for Treatment of Skin Tightening and Improvement of Hand Function in Scleroderma

Scleroderma

United States
George Washington University

Completed

The Scleroderma Biorepository and Pathogenesis Study (STOP Scleroderma)

Scleroderma

United States
University of Texas Southwestern Medical Center

Completed

The Effects of Botulinum Toxin on Oral Aperture in Patients With Scleroderma

Scleroderma

United States
Cytori Therapeutics

Withdrawn

Scleroderma Treatment With Celution Processed ADRCs Registry (STAR)

Scleroderma
University of California, San Francisco
Roche Pharma AG

Completed

Pulmonary Involvement in Scleroderma: A Clinical Study of the Safety and Efficacy of Mycophenolate Mofetil in Scleroderma Patients With Lung Involvement

Scleroderma, Systemic

United States
University of Michigan
University of Alabama at Birmingham

Completed

Novel Rehabilitation Strategies to Improve Arm Function in Patients With Scleroderma

Scleroderma | Ssc

United States
Centre Hospitalier Universitaire de Nice

Recruiting

microRNAs in Systemic Scleroderma (Dig-ScS)

Scleroderma, Systemic

France
University Hospital, Limoges

Completed

Scleroderma: Functional Disability Between the Dominant and Contralateral Hand. (SCLERO-HAND)

Scleroderma, Systemic

France
National Institute of Arthritis and Musculoskeletal...
Medical University of South Carolina; Johns Hopkins University; University of... and other collaborators

Completed

Oral Type I Collagen for Relieving Scleroderma

Connective Tissue Diseases | Scleroderma

United States
University Hospital, Lille

Completed

Sildenafil Effect on Digital Ulcer Healing in sClerodErma SEDUCE STUDY (SEDUCE)

Systemic Scleroderma

France
Icahn School of Medicine at Mount Sinai
Columbia University; New York Stem Cell Foundation Research Institute

Completed

Mitochondrial Dysfunction and Disease Progression

Clinically Isolated Syndrome | Relapsing-Remitting Multiple Sclerosis | Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

United States
Power Life Sciences Inc.

Not yet recruiting

Delving Into Participation Trends of Scleroderma Clinical Trials

Scleroderma

United States
Paracrine, INC.

Not yet recruiting

ADRCs in The Treatment of Hand Dysfunction Due to Scleroderma (STAR-II)

Scleroderma, Diffuse
Hospital for Special Surgery, New York

Recruiting

Scleroderma Registry & Repository at the Hospital for Special Surgery

Scleroderma

United States
University Hospital, Rouen

Completed

Genesis of Scleroderma: Role of Environmental Factors in 100 Patients With Scleroderma and 300 Controls

Scleroderma

France
MedImmune LLC

Completed

A Study of the Safety and Tolerability of MEDI-551 in Scleroderma

Scleroderma

United States, United Kingdom, Canada
Mayo Clinic

Completed

Finger Hardness Measure in Scleroderma

Scleroderma

United States
MedImmune LLC

Completed

A Study to Evaluate Safety and Tolerability of Multiple Doses of MEDI-546 in Adult Subjects With Scleroderma (MEDI-546)

Scleroderma

United States
Federal University of São Paulo

Completed

Effectiveness and Safety of Lidocaine for Scleroderma

Scleroderma

Brazil
University of Michigan

Completed

Scleroderma ARFI Imaging of the Skin (ARFI)

Scleroderma

United States
The Hospital for Sick Children

Completed

Imiquimod in Children With Plaque Morphea

Scleroderma, Localized

Canada
University of Michigan
Rheumatology Research Foundation

Completed

RENEW Scleroderma: A Peer-Mentored, Web Intervention for Resilience-based, Energy Management to Enhance Wellbeing and Fatigue (RENEW)

Scleroderma

United States
Indonesia University
Netherlands: Ministry of Health, Welfare and Sports

Completed

The Effect of Ethanol Extract Physalis Angulata Linn. in Scleroderma Patients With Standard Therapy

Scleroderma

Indonesia
University Hospital, Lille

Recruiting

Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease (KETAPAL)

Depression

France
University Hospital, Lille

Terminated

Assessment of the Prevalence of Olfactory Disorders in Systemic Scleroderma (SCLEROLF)

Scleroderma | Olfactory Disorders

France
Boston University
Regeneron Pharmaceuticals

Completed

IL1-TRAP, Rilonacept, in Systemic Sclerosis

Systemic Sclerosis | Scleroderma | Diffuse Systemic Sclerosis | Diffuse Scleroderma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Scleroderma Treatment With Autologous Transplant (STAT) Study (STAT)

Systemic Scleroderma

United States
Lady Davis Institute

Completed

The SPIN - Scleroderma Support Group Leader EDucation Program Trial (SPIN-SSLED) (SPIN-SSLED)

Scleroderma, Systemic

Canada

Clinical Trials on Progressive Scleroderma

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