Clinical Trials on Rectal Cancer

Total 125987 results

University of California, San Francisco

Terminated

Evaluation of Rectal Cancer Treatment Response Using PET/MRI (Rectal PET/MRI)

Rectal Adenocarcinoma

United States
IHU Strasbourg

Terminated

Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to Histopathology (TRaMA)

Rectal Cancer | Rectal Adenocarcinoma

France
University Hospital, Tours

Recruiting

Colorectal Cancer Screnning Colonoscopy Under Hypnosis (CODEPICCH)

Colorectal (Colon or Rectal) Cancer

France
University of Chicago

Recruiting

Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions

Cancer | Advanced Solid Tumor | Advanced Cancer | Behavior Disorders | Mental Health Issue

United States
Targovax ASA

Terminated

Exploratory Study of TG02-treatment as Monotherapy or in Combination With Pembrolizumab to Assess Safety and Immune Activation in Patients With Locally Advanced Primary and Recurrent Oncogenic RAS Exon 2 Mutant Colorectal Cancer

Rectal Cancer

New Zealand, Australia
Tampere University Hospital
Turku University Hospital; Helsinki University Central Hospital; Oulu University... and other collaborators

Not yet recruiting

Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer (NORPPA-1)

Rectal Cancer | Rectal Adenocarcinoma

Finland, Estonia
GlaxoSmithKline

Recruiting

A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer (AZUR-1)

Neoplasms, Rectal

United States, France, Italy, Japan, Spain, United Kingdom, Germany, Korea, Republic of, Canada, Netherlands
Liz-Anne Lewsley
AstraZeneca; NHS Greater Glasgow and Clyde; University of Glasgow

Not yet recruiting

A Trial of Durvalumab (MEDI 4736) in Combination With Extended Neoadjuvant Regimens in Rectal Cancer (PRIME-RT)

Rectal Cancer | Rectal Neoplasms | Rectal Adenocarcinoma
Southwest Hospital, China

Recruiting

PR in Endoscopic LAR for Rectal Cancer

Rectal Carcinoma

China
Osama Rahma, MD
Merck Sharp & Dohme LLC; Hoosier Cancer Research Network

Withdrawn

Trial of Chemoradiation and Pembrolizumab in Patients With Rectal Cancer

Rectal Cancer | Rectal Neoplasm
Instituto do Cancer do Estado de São Paulo

Recruiting

Effect of a Post-operative Protocol of Early Mobilization on Functional Recovery and Postoperative Complications After Immediate Internal Pudendal Artery Perforator Flap Reconstruction for Irradiated Abdominoperineal Resection Defects: a Prospective, Randomized and Controlled Clinical Study.

Rectal Cancer

Brazil
University Hospital, Caen

Not yet recruiting

Role of Empathy in Curative Treatment Outcomes of Non-metastatic Colorectal Cancer. (EMPACOL)

Quality of Life | Morality | Morbidity | Empathy | Non-metastatic Colorectal Cancer
Erasca, Inc.

Active, not recruiting

A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies (HERKULES-3)

Metastatic Colorectal Cancer | Metastatic Pancreatic Ductal Adenocarcinoma

United States
Siemens Molecular Imaging

Completed

Study of [F 18]HX4 Positron Emission Tomography (PET) as a Tool to Detect Hypoxia in Tumors (HX4-200)

Cervical Cancer | Head and Neck Cancer | Lung Cancer | Rectal Cancer | Liver Cancer
Shoichi Fujii, MD, PhD

Unknown

Randomized Controlled Trial to Evaluate High Tie Versus Low Tie of the Inferior Mesenteric Artery in Anterior Resection

Rectal Cancer | Colon Rectal Resection

Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Assessment of Symptom-Related Cytokines in Lung and Gastrointestinal (GI) Cancer Patients

Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Lung Cancer | Anal Cancer

United States
Sahlgrenska University Hospital, Sweden

Recruiting

ANCA II - Quality of Life and Functional Outcome in Patients With Anal Cancer (ANCAII)

Anal Cancer

Sweden
National Cancer Institute (NCI)

Active, not recruiting

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | Vulvar, Vaginal, Penile, Rectal Cancer | HPV Positive Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Biomarkers in Tissue Samples From Patients With Newly Diagnosed Breast Cancer Treated With Zoledronic Acid

Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Estrogen Receptor-positive Breast Cancer | Progesterone Receptor-positive Breast Cancer | Invasive Ductal Breast Carcinoma

United States
University of Chicago

Suspended

Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy

Gastric Cancers

United States
British Columbia Cancer Agency
Genome British Columbia; BC Cancer Foundation

Unknown

Real-world Clinical Effectiveness of Whole Genome and Transcriptome Analysis to Guide Advanced Cancer Care

Metastatic Cancer | Advanced Cancer | Cancers That Cannot be Treated With Curative Intent
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors

Lung Cancer | Metastatic Cancer | Bladder Cancer | Renal Cancer | Melanoma Cancer | Head/Neck Cancers

United States
Cardiff University

Recruiting

Phase 1b/II Trial of Pembrolizumab Plus IMRT in Stage III/IV Carcinoma of Anus (CORINTH)

Anal Cancer Stage III A | Anal Cancer Stage III B

United Kingdom, Norway
Hospital de Mataró

Recruiting

Validation of a Multimodal Algorithm for the Treatment of Fecal Incontinence

Fecal Incontinence

Spain
Istanbul Medipol University Hospital

Unknown

PRP Injection Into Anal Sphincters for Fecal Incontinence

Fecal Incontinence

Turkey
University of Aarhus

Completed

Dose Response Curve - Sacral Nerve Stimulation for Faecal Incontinence

Fecal Incontinence

Denmark
University of Michigan
Early Detection Research Network

Completed

Validation of Colon Biomarkers for the Early Detection of Colorectal Adenocarcinoma (GLNE010)

Rectal Cancer | Colon Cancer

United States, Germany, Canada
Jerome Canady, M.D.

Active, not recruiting

Canady Helios Cold Plasma Scalpel Treatment at the Surgical Margin and Macroscopic Tumor Sites

Stage IV Lung Cancer | Stage IV Bladder Cancer | Stage IV Pancreatic Cancer | Recurrent Malignant Solid Neoplasm | Stage IV Breast Cancer | Stage IV Renal Cell Cancer | Stage IV Prostate Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer | Stage IV Gastric Cancer | Stage IV Non-small Cell Lung Cancer | Stage... and other conditions

United States
Hospital de Mataró

Completed

Study of the Efficacy of 4 Treatments for Fecal Incontinence in Community-dwelling Women

Fecal Incontinence
University of Colorado, Denver
National Cancer Institute (NCI)

Recruiting

A Pilot Study Evaluating the Effect of 2D Antiscatter Grids on CBCT Image Quality

Prostate Cancer | Head and Neck Cancers | Upper Abdomen Cancers

United States
National Taiwan University Hospital
National Taiwan University

Recruiting

Using Wearable Device to Improve Quality of Palliative Care

End Stage Cancer | Terminal Cancer

Taiwan
Cancer Institute and Hospital, Chinese Academy...

Unknown

The Effect of Bone Marrow-sparing Intensity-Modulated Radiotherapy to GI Cancer (IMRT)

Gastric Cancer | Rectal Cancer | Adverse Effect of Radiation Therapy | Bone Marrow Toxicity

China
Fujian Cancer Hospital

Not yet recruiting

A Phase II Clinical Study of the Efficacy and Safety of Tislelizumab Combined With Fruquintinib and Chidamide in the Treatment of Unresectable or Advanced Microsatellite Stabilized (MSS/pMMR) Colorectal Cancer With Liver Metastases

Colo-rectal Cancer
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Not yet recruiting

Tucatinib Combined With Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T Study

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colon Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8

United States
German Breast Group
Roche Pharma AG; Amgen; Teva Pharmaceuticals USA; Vifor Pharma

Completed

A Phase III Trial Comparing Two Dose-dense, Dose-intensified Approaches (ETC and PM(Cb)) for Neoadjuvant Treatment of Patients With High-risk Early Breast Cancer (GeparOcto)

Inflammatory Breast Cancer | HER2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III

Germany
Qu Shen
The First Affiliated Hospital of Xiamen University

Not yet recruiting

Multidimensional Rehabilitation Intervention in Colorectal Cancer Survivors

Quality of Life | Rehabilitation | Colorectal Cancer Survivor
Lund University Hospital

Active, not recruiting

Observational Study of Early Contact With Palliative Care Unit for Patients Receiving First Line Palliative Chemotherapy With Cancer in Upper Gastrointestinal Canal, or Second Line Palliative Chemotherapy in Patients With Colorectal Cancer - an Open, Randomised Investigator Initiated Trial. (ALLAN)

Tumor in Upper Gastrointestinal Canal or Patients With Colorectal Cancer

Sweden
Institut Cancerologie de l'Ouest
Merck Sharp & Dohme LLC

Terminated

Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy Alone in Rectal Adenocarcinoma (UFT RT Phase 3)

Rectal Cancer | Stage II/III | T3 or T4 (Only Anal Extension) Rectal Cancer | N0-2 | M0

France
Cancer Institute and Hospital, Chinese Academy...

Unknown

Short Course Radiotherapy Combined With Chemotherapy in Stage IV Rectal Cancer With Resectable Liver Metastases

Stage IV Rectal Cancer, Liver Metastasis, Resectable

China
German Breast Group
Celgene Corporation; Amgen

Completed

Denosumab as an add-on Neoadjuvant Treatment (GeparX) (GeparX)

Inflammatory Breast Cancer | HER2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III

Germany
Beijing Friendship Hospital
Changhai Hospital; The First Affiliated Hospital of Anhui Medical University; Fudan University and other collaborators

Recruiting

A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer: From a Multicenter Phase II Cohort to a Phase III Randomized Controlled Study

Locally Advanced Rectal Carcinoma

China
University of Hull
Hull University Teaching Hospitals NHS Trust

Not yet recruiting

Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer

Locally Advanced Rectal Carcinoma
Sixth Affiliated Hospital, Sun Yat-sen University

Active, not recruiting

Deep Learning Based MRI Radiomics in Predicting the Clinical Risk of Locally Advanced Rectal Cancer

Locally Advanced Rectal Carcinoma
Sixth Affiliated Hospital, Sun Yat-sen University

Completed

Assessment of Efficacy of Neoadjuvant Therapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal Carcinoma
Genomictree, Inc.
Severance Hospital

Completed

Clinical Validation of Stool DNA-based SDC2 Methylation Test for Colorectal Cancer Detection

Healthy | Colorectal Cancer | Polyps | Other Cancers

Korea, Republic of
KU Leuven
Universitaire Ziekenhuizen KU Leuven

Not yet recruiting

Personalized Care Pathways for Bowel Symptoms in Rectal Cancer patients_development of E-diary (Treatable)

Rectal Cancer | LARS - Low Anterior Resection Syndrome
University Hospital, Ghent

Completed

Rectal Cancer Survivorship: Impact of Low Anterior Resection Syndrome (LARS) on the Quality of Life

Low Anterior Resection Syndrome | Rectal Cancer

Belgium
Abramson Cancer Center of the University of Pennsylvania

Completed

FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer

Adenocarcinoma | Rectal Cancer | Metastasis | Colon Cancer

United States
University Medical Center Groningen

Not yet recruiting

Evaluating PD-1/PD-L1 in Locally Advanced Rectal Cancer by Quantitative Fluorescence Molecular Endoscopy (PREDICT)

Locally Advanced Rectal Carcinoma

Netherlands
University of Hull
Hull University Teaching Hospitals NHS Trust

Not yet recruiting

Exercise for Improving Radiotherapy Efficacy in Rectal Cancer

Locally Advanced Rectal Carcinoma

Clinical Trials on Rectal Cancer

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