Clinical Trials on Retinal Structural Change, Deposit and Degeneration

Total 1876 results

Edward J. Holland
Alcon Research; Sirion Therapeutics, Inc.; Parsons Medical Communications

Completed

Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery.

Corneal Edema | Cataracts | Visual Acuity Reduced Transiently | Retinal Structural Change, Deposit and Degeneration

United States
Minia University

Completed

Surgical Management of Optic Disc Pit Maculaopathy

Maculopathy | Optic Disc Structural Anomaly
Benha University

Recruiting

Changes After Suprachoroidal Injection.

Macular Edema | Cataract | Intraocular Pressure | Retina; Change

Egypt
Institut de la Macula y la Retina
Igen BioLab SLU

Recruiting

Study to Evaluate the Response to Supplementation With Postbiotics in Patients With Macular Degeneration. (REVERS)

AMD | Drusen Stage Macular Degeneration | Soft Drusen | Reticular Pseudodrusen | Drusen (Degenerative) of Macula, Bilateral

Spain
University Hospital "Sestre Milosrdnice"

Completed

The Association of the Peripheral Retinal Changes and Genotypic Changes in Patients With Age Related Macular Degeneration

Peripheral Retinal Degenerations, Age Related Macular Degeneration Polymorphisms
Eunice Kennedy Shriver National Institute of Child...

Withdrawn

Effects of Sun Filters on Age-related Macular Degeneration in People With Lens Implants

Age-Related Macular Degeneration | Age-Related Macular Changes | Cataract and IOL Surgery | Retinal Photochemistry
Inje University
Allergan

Unknown

Effect of Dexamethasone Implant in Hard Exudate Complicated With Diabetic Macular Edema

Diabetes Mellitus | Macular Edema | Retinal Exudates and Deposits

Korea, Republic of
University of Illinois at Chicago

Completed

Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration

Retinal Degenerations

United States
Johns Hopkins University

Terminated

Pro-permeability and Pro-fibrosis Factors in the Aqueous of Patients With Retinal Diseases (P3F2)

Macular Edema | Fibrosis of the Retina

United States
Ospedale San Raffaele
University of Rome Tor Vergata; University of Genova; Fondazione G.B. Bietti,...

Recruiting

Subthreshold Laser Treatment for Reticular Pseudodrusen Secondary to Age-related Macular Degeneration (PASCAL-RPD)

Macular Degeneration, Dry | Macular Degeneration, Senile | Laser Burn of Retina | Macular Degeneration Intermediate

Italy
Johns Hopkins University

Completed

Bevicizumab (Avastin) Infusion for Choroidal Neovascularization (CNV) Not Associated With Age-Related Macular Degeneration (AMD)

Choroidal Neovascularization | Pathological Myopia | Degenerative Myopia
Manhattan Eye, Ear & Throat Hospital
Alcon Research

Completed

Treatment of Conditions With Open Label-Anecortave Acetate Sterile Suspension ( 15mg.) Where Lesions do Not Meet Acceptable Criteria for Standard Care.

Age-Related Macular Degenerations. | Subfoveal Neovascularization.

United States
Xun Xu
Peking University; Zhongshan Ophthalmic Center, Sun Yat-sen University; Air Force... and other collaborators

Unknown

Pharmacogenomic Study on Anti-VEGF Medicine in Treatment of Macular Neovascular Diseases

Age-Related Macular Degeneration | Polypoidal Choroidal Vasculopathy | Pathological Myopia | Conbercept | Pharmacogenomic

China
Hospital Universitari Vall d'Hebron Research Institute

Not yet recruiting

Single Perclose Escalation Technique for Vascular Closure in TAVR

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Spain
Sohag University

Not yet recruiting

Optical Coherence Tomography Angiography Criteria Of The Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia (Comparative Study).

Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Recruiting

The ReTAVI Prospective Observational Registry

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Austria, Spain, France, Germany, Italy, Switzerland, Poland, Canada, Israel, Netherlands, Portugal, United Kingdom
Medical University of Vienna

Completed

An Open Study Comparing the Effects of Moxaverine on Ocular Blood Flow in Patients With Age- Related Macular Degeneration, Primary Open Angle Glaucoma and Healthy Control Subjects

Glaucoma | Macular Degeneration | Regional Blood Flow

Austria
Medical University of Vienna

Completed

Choroidal Blood Flow and Progression of Age-Related Macular Degeneration in the Fellow Eye in Patients With Unilateral Choroidal Neovascularisation

Regional Blood Flow

Austria
National Eye Institute (NEI)

Active, not recruiting

Vitamin A Palmitate Supplementation in People With Age-Related Macular Degeneration (and Without Reticular Pseudodrusen) and Delayed Dark Adaptation

AMD

United States
National Eye Institute (NEI)

Completed

Generation of Induced Pluripotent Stem (iPS) Cell Lines From Skin Fibroblast Cells of Participants With Age-Related Macular Degeneration

AMD

United States
Lee's Pharmaceutical Limited

Unknown

TAB014(Drug Code) in Wet( Neovascular)Age-related Macular Degeneration(AMD) Subjects

AMD

China
Centre Hospitalier Intercommunal Creteil
Bayer

Active, not recruiting

CNV in AMD Analyzed by OCT Angiography Under IntravitreaL Eylea (COCTAEyl) (COCTAEyl)

AMD | Exudative Macular Degeneration

France
Moorfields Eye Hospital NHS Foundation Trust
Medical Research Council

Completed

Production of iPSC Derived RPE Cells for Transplantation in AMD

Age Related Macular Degeneration (AMD)
Novartis Pharmaceuticals

Completed

Real-world Evaluation of Brolucizumab for the Treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) (Komodo Health)

Age-related Macular Degeneration (AMD)

United States
Novartis Pharmaceuticals

Completed

Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Age-related Macular Degeneration (AMD) Who Received Anti-vascular Endothelial Growth Factor (VEGF) Agents (Komodo Health)

Age-related Macular Degeneration (AMD)

United States
Novartis Pharmaceuticals

Completed

Characteristics of Patients With Neovascular Age-related Macular Degeneration Enrolled in the Brolucizumab Patient Support Services Program

Age-related Macular Degeneration (AMD)

United States
University Hospital, Limoges

Unknown

Assessment of the Knowledge and Needs of Patients With AMD Before a Therapeutic Patient Education Program is Put in Place (DEMELE)

Age-related Macular Degeneration (AMD)

France
National Eye Institute (NEI)

Completed

AMD Phenotype and Genotype Study

Age-Related Macular Degeneration | AMD

United States, Germany
Pfenex, Inc

Completed

Safety Study of PF582 Versus Lucentis in Patients With Age Related Macular Degeneration

Age Related Macular Degeneration (AMD)

New Zealand
Tel Aviv Medical Center

Completed

Pars Plana Vitrecromy in Patients Aged 85 Years and Above (PPV)

Age Related Macular Degeneration | Retinal Detachment | Vitreous Injury
Moorfields Eye Hospital NHS Foundation Trust
King's College London; Cardiff University; University College, London; Newcastle... and other collaborators

Recruiting

Quality-Assured Follow-up of Quiescent Neovascular Age -Related maculaR dEgeneration by Non-medical Practitioners (FENETRE)

AMD

United Kingdom
Changhua Christian Hospital

Completed

Real World Outcomes of Intravitreal Anti-vascular Endothelial Growth Factors for Neovascular Age Related Macular Degeneration in Taiwan (OIVAEGFFAMDIT)

AMD

Taiwan
Regeneron Pharmaceuticals

Completed

Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection) (RE-VIEW)

Age - Related Macular Degeneration (AMD)

United States
Retina Implant AG

Terminated

Impact on Daily Life of Patients Using the Subretinal Implant RETINA IMPLANT Alpha AMS

Retinal Degeneration | Inherited Retinal Dystrophy Primarily Involving Sensory Retina

France
VA Office of Research and Development
Augusta University

Not yet recruiting

Rehabilitating Vision Loss in Veterans With Age-Related Macular Degeneration (AMD)

Age-related Macular Degeneration (AMD)

United States
Alcon Research
Novartis Institutes for BioMedical Research

Terminated

Safety Tolerability and Efficacy of Intravitreal LMG324 in the Treatment of Neovascular Age-Related Macular Degeneration

Age-related Macular Degeneration (AMD)

United States
Newtricious R&D BV
Sprim Advanced Life Sciences

Completed

Intervention Trial in Early Age-related Macular Degeneration (I-TEAM)

Age-related Macular Degeneration (AMD)

United States, Germany, Netherlands, United Kingdom
Eyetech Pharmaceuticals
Pfizer

Unknown

A Clinical Trial to Explore the Safety and Efficacy of Injections of Macugen When Given Every 6 Weeks in Subjects With AMD

Age-Related Macular Degeneration (AMD)

United States
Osias Francisco de Souza

Unknown

Evaluation of Changes in the Parameters of Optical Coherence Tomography After Intravitreal Injection of Lucentis

Degeneration of Macula and Posterior Pole

Brazil
Novartis Pharmaceuticals

Completed

Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Agerelated Macular Degeneration (AMD) Who Received Anti-VEGF Agents (IRIS Registry)

Age-related Macular Degeneration (AMD)

United States
The First Affiliated Hospital with Nanjing Medical...

Unknown

Treatment of Age-related Macular Degeneration by Fetal Retinal Pigment Epithelial Cells Transplantation

Macular Degeneration | Age Related Macular Degeneration | AMD

China
University of California, San Diego
Regeneron Pharmaceuticals

Completed

EAGLE: Evaluating Genotypes Using Intravitreal Aflibercept Injection (EAGLE)

Macular Degeneration | Wet Macular Degeneration

United States
Università degli Studi di Brescia

Completed

Pilot Study of Ranibizumab With and Without Ketorolac Eyedrops for Exudative Age-related Macular Degeneration

Wet Macular Degeneration

Italy
Minia University

Unknown

Amniotic Membrane for Recurrent Macular Hole

Retinal Detachment | Myopic Macular Degeneration | Macula Hole

Egypt
Augenabteilung Allgemeines Krankenhaus Linz

Unknown

Spectral-domain Optical Coherence Tomography of the Eye

Diabetes | Diabetic Macular Edema | Macular Edema | Cornea | Retina | Refractive Surgery

Austria
VA Office of Research and Development

Recruiting

Active AMD Study to Improve Function in Veterans

Age Related Macular Degeneration (AMD)

United States
Frank G. Holz
Radboud University Medical Center; Bayer; Hoffmann-La Roche; Novartis Pharmaceuticals and other collaborators

Active, not recruiting

Development of Novel Clinical Endpoints in Intermediate AMD (MACUSTAR)

Age Related Macular Degeneration (AMD)

Germany, Italy, Netherlands, United Kingdom, France, Portugal, Denmark
Novartis Pharmaceuticals

Completed

Real-world Evaluation of Brolucizumab for the Treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) (IRIS Study)

Age-related Macular Degeneration (AMD)

United States
Novartis Pharmaceuticals

Completed

Evaluation of Number of Patient Eyes That Remained on or Switched to Anti-VEGF Treatment After Initiation of Broluciumab

Age-related Macular Degeneration (AMD)

United States
Bioeq GmbH

Completed

Efficacy and Safety of the Biosimilar Ranibizumab FYB201 in Comparison to Lucentis in Patients With Neovascular Age-related Macular Degeneration (COLUMBUS-AMD)

Age-related Macular Degeneration (AMD)

France, Italy, Poland, Russian Federation, Spain, United Kingdom, Germany, Hungary, Ukraine, Austria, Czechia, Israel

Clinical Trials on Retinal Structural Change, Deposit and Degeneration

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