Clinical Trials on SMA

Total 173 results

Institute of Child Health
Great Ormond Street Hospital for Children NHS Foundation Trust

Not yet recruiting

Exploring Bulbar Function, Speech And Communication Development in SMA Type 1 (ExSpAnD SMA)

SMA1
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; Direction...

Completed

Differential Study of Muscle Transcriptome (TRANE)

ALS | SMA | SBMA

France
Danish Headache Center

Completed

The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.

Headache | Dilatation of Cranial Arteries; MMA, STA and MCA

Denmark
Amsterdam UMC, location VUmc
Radboud University Medical Center; Maastricht University Medical Center; GGZ... and other collaborators

Recruiting

TMS for Exposure Therapy Resistant OCD (TETRO)

1 Hz Real rTMS to the Pre-SMA | 1 Hz Sham rTMS to the Pre-SMA

Netherlands
Wiktor Dega University Orthopedic and Rehabilitation...

Recruiting

A Head-to-head Study Comparing the Functional Value of Two Models of Robotically Assisted Rehabilitation in SMA (Spinal Muscular Atrophy) Patients (SMArt)

SMA

Poland
Dr.Mahak Mehta

Completed

Comparison Between Three Supraglottic Airway Devices ProSeal Laryngeal Mask Airway, Air-Q LMA and Ambu AuraGain

Proseal LMA vs Air-Q LMA vs Ambu AurGain LMA
Heidelberg University

Recruiting

Evaluation of Biomarkers of COPD Exacerbation

SAA Level and SAA/Lipoxin A4 Ratio

Germany
Groupe Francophone des Myelodysplasies
Advancell - Advanced In Vitro Cell Technologies, S.A.

Terminated

GFM-Acadesine: A Phase I-II Trial of Acadesine (Acadesine)

SMD

France
Yonsei University

Withdrawn

A Prospective Comparison of Robotic and Endoscopic SMG Resection Via Retroauricular Approach

SMG Resection in Comparison to Endoscopic SMG Resection

Korea, Republic of
Brigham and Women's Hospital

Completed

Establishing 18F-PBR06 PET Imaging as a Viable Pharmacodynamic Endpoint in MSA

MSA

United States
Assistance Publique - Hôpitaux de Paris

Completed

Study to Evaluate the Efficacy of Riluzole in Children and Young Adults With Spinal Muscular Atrophy (SMA) (ASIRI)

SMA

France
St. Louis University

Completed

Text4Peds: Short Message Service Evaluating Medical Student Education

SMS | Education, Medical, Undergraduate

United States
Mette Cathrine Oerngreen
Elsass Foundation

Recruiting

Paracetamol Study in Patients With Low Muscle Mass

Cerebral Palsy | SMA II

Denmark
Milton S. Hershey Medical Center
BioSensics

Recruiting

Digital Tools for Assessment of Motor Functions and Falls in ALS

ALS | PLS | PMA

United States
Rabin Medical Center
Pfizer

Completed

Growth and Metabolic Response to GH and GnRHa Treatment Versus GH Alone in Boys Born SGA.

SGA and Growth

Israel
C. R. Bard
Tepha, Inc.

Completed

GalaFlex Mesh in Facelift

Superficial Musculoaponeurotic System (SMAS) Procedure

United States
Pfizer

Completed

Retrospective Study Of The Influence Of Age At Start Of Growth Hormone Treatment On Height Gain In Children Born Small for Gestational Age (GH-RAST)

Small For Gestational Age (SGA)

Spain
MarsiBionics
National Research Council, Spain; Hospital Universitario La Paz

Completed

Rehabilitative Effect of the Use of a Gait Exoskeleton in Patients With Neuromuscular Disease or Cerebral Palsy

Cerebral Palsy | Neuromuscular Diseases | SMA II

Spain
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S., an affiliate of Merck KGaA, Darmstadt, Germany

Completed

Optimization of the Dosage Regimen of Growth Hormone Therapy in Children Born Small for Gestational Age (SGA OPTIMIS)

Small Gestational Age (SGA)
Yeditepe University Hospital

Completed

A Method to Determine the Size of Laryngeal Mask Airway (LMA)

Ear Based ProSeal LMA

Turkey
MarsiBionics
Hospital Universitario La Paz

Completed

Evaluation of the Exoskeleton ATLAS 2030 as Robot-assisted Physical Therapy to Children With Neuromuscular Diseases

Cerebral Palsy | Neuromuscular Diseases | SMA II

Spain
Rejuven Dermaceutical Co., Ltd.

Completed

RJV001 Study in Adults Receiving Abdominoplasty

Submental Fat (SMF) | Double Chin

United States
Ajou University School of Medicine

Completed

Videoscope Guided Flexible LMA Insertion

Ideal Position of LMA Flexible

Korea, Republic of
Samsung Medical Center

Completed

Optimal Head Rotation and External Landmark for Internal Jugular Vein Cannulation After Placement of Proseal Laryngeal Mask Airway

General Anesthesia With Laryngeal Mask Airway (LMA)

Korea, Republic of
Sandoz

Terminated

Long-term Safety Follow-up After Growth Hormone Treatment of Short Children Born Small for Gestational Age (SGA)

Short Children Born Small for Gestational Age (SGA)

Czechia, Germany, Hungary, Poland, Georgia, Romania
RWTH Aachen University

Completed

Emergence Times and Airway Reactions in General Laryngeal Mask Airway Anesthesia

Anesthesia With Use of LMA (Laryngeal Mask Airway)

Germany
Inje University

Completed

Effectiveness of Fixed PC Interval Using SMS for Afternoon Colonoscopy

Effectiveness of SMS to Fix PC Interval

Korea, Republic of
University of South Carolina
Emory University; Duke University; National Institute for Medical Research, Tanzania and other collaborators

Not yet recruiting

Chanjo Kwa Wakati - Improving Vaccination Coverage and Timeliness in Rural Settings (MINT-II)

Knowledge, Attitudes, Practice | Incentives | Vaccination | Short Message Service (SMS)

Tanzania
University Hospital, Caen

Completed

Motion Sickness on Astrolabe's Vessel (SICKVEST)

Sea Sickness

France
Interactive Research and Development

Completed

Use of SMS and Interactive Reminders to Improve Timely Immunization Coverage

SMS | Immunization; Infection
Pope Research Corporation
Abbott; Academic Medical Organization of Southwestern Ontario

Completed

Closing the Gap in Care in Seronegative Inflammatory Arthritis (Metrix II)

SpA | PsA

Canada
University of Colorado, Denver
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

SMS Mobile Technology to Improve Early Childhood Vaccine Coverage in Guatemala (SMSVaxGuate)

Adherence to Vaccination Schedules | Timeliness of Vaccination | Acceptability of SMS Reminder Program

Guatemala
Société des Produits Nestlé (SPN)

Completed

An Observational Study to Characterize Human Milk From Mothers Delivering Term SGA and AGA Infants.

Small for Gestational Age (SGA) Infants | Appropriate for Gestational Age (AGA) Infants

India
African Strategies for Health
United States Agency for International Development (USAID)

Unknown

Impact Evaluation of the Pilot SMS Mother Reminder System

Effects of the SMS Mother Reminder System on Use of Health Care.

Uganda
Ain Shams University

Completed

I-gel Versus Air-Q LMA for Pediatric Patients

Easy Insertion, Complications Ans Suitability of i Gel and Air Q LMA

Egypt
University of Oxford
Wellcome Trust; University of Cape Town; EPSRC

Completed

Effectiveness of SMS-text Message Support for Patients With Hypertension to Improve Blood Pressure (*StAR)

Hypertension | mHealth | SMS-text
Cairo University

Completed

Randomized Comparative Study Between Classic Laryngeal Mask Airway and I Gel Airway in Obese Patients Having BMI 35-40 During Elective Non Abdominal Surgery.

LMA Vs I Gel

Egypt
Makassed General Hospital

Completed

Four vs. Ten Local Anesthetic Injections for SMR

Submucosal Resection of the Nasal Septum (SMR)

Lebanon
Novartis Pharmaceuticals

Terminated

LDE225 for Patients With PTCH1 or SMO Mutated Tumors (SIGNATURE)

PTCH1 or SMO Activated Solid and Hematologic Tumors

United States
University of Bern
University Hospital Inselspital, Berne; University of Lausanne Hospitals; University... and other collaborators

Recruiting

Swiss Registry for Neuromuscular Disorders (Swiss-Reg-NMD)

Congenital Muscular Dystrophy | SMA | DMD | BMD | IMD

Switzerland
GeneCradle Inc

Recruiting

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 2 Patients

SMA II

China
Repurposed Therapeutics, Inc.
National Aeronautics and Space Administration (NASA)

Recruiting

Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance

Motion Sickness | Sea Sickness | Motion Sickness, Space

United States
Medical Corps, Israel Defense Force

Completed

Video Head Impulse Test and Seasickness Susceptibility

Sea Sickness

Israel
University Hospital Inselspital, Berne

Completed

Evaluation of Supraglottic Airway Devices in Children and Comparison to Historic Control

Evaluation of Success Rate | Airway Leak Pressure | Side Effects of LMA Supreme in Pediatric Patients Undergoing General Anesthesia

Switzerland
Biocad

Recruiting

Study of the Safety and Efficacy of an Adeno-Associated Viral Vector Carrying the SMN Gene After a Single Intravenous Administration of Escalating Doses in Children With Spinal Muscular Atrophy (BLUEBELL) (BLUEBELL)

Spinal Muscular Atrophy (SMA)

Belarus, Russian Federation
Ohio State University
Massachusetts General Hospital; National Institute of Neurological Disorders... and other collaborators

Completed

Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development

Spinal Muscular Atrophy (SMA)

United States
Hoffmann-La Roche

Recruiting

A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular Atrophy (MANATEE)

Spinal Muscular Atrophy (SMA)

Belgium, United States, Croatia, Japan, Netherlands, Spain, Canada, Poland, United Kingdom, Italy, Portugal, Australia
Hugh McMillan
Families of Spinal Muscular Atrophy; Gwendolyn Strong Foundation

Terminated

Effect of Low-Dose Celecoxib on SMN2 in Patients With Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA)

Canada
Biohaven Pharmaceuticals, Inc.

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy (RESILIENT)

Neuromuscular Diseases | Spinal Muscular Atrophy | SMA

United States, Netherlands, United Kingdom, Spain, Czechia, Belgium, Germany, Italy, Poland
Novartis Gene Therapies

Completed

Single-Dose Gene Replacement Therapy Clinical Trial for Participants With Spinal Muscular Atrophy Type 1 (STRIVE-EU)

SMA

France, United Kingdom, Italy, Belgium

Clinical Trials on SMA

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mozambique

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Rare Diseases

Drug Interventions

Dietary Supplements

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