Clinical Trials on Sepsis

Total 3108 results

Duke University
Duke Clinical Research Institute; Data & Society Research Institute

Completed

Implementation and Evaluations of Sepsis Watch

Sepsis | Septic Shock | Severe Sepsis

United States
Bristol-Myers Squibb

Terminated

Safety, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Severe Sepsis

Septic Shock | Severe Sepsis

United States
Nur Baykara
Turkish Society of Intensive Care, Sepsis Study Group

Completed

Epidemiology of Sepsis in Turkish ICUs.

Sepsis | Septic Shock | Severe Sepsis
Chinese PLA General Hospital
Beijing Institute of Basic Medical Science

Completed

Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis

Sepsis | Septic Shock | Severe Sepsis

China
RWTH Aachen University

Completed

German Lactat Clearance in Severe Sepsis (GLASS)

Septic Shock | Severe Sepsis

Germany
National Taiwan University Hospital

Completed

Outcomes of Severe Sepsis Patients in Surgical Intensive Care Units

Septic Shock | Severe Sepsis

Taiwan
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
European Society of Intensive Care Medicine

Completed

Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis

Septic Shock | Severe Sepsis

Italy
National Institute of General Medical Sciences...

Completed

Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation (LactATES)

Septic Shock | Severe Sepsis

United States
Centre Hospitalier Universitaire de Nice

Unknown

Comparison of Sensitivity Between Presepsine and Lactate for the Diagnosis of Severe Sepsis. (PREDI)

Severe Sepsis and Septic Shock

France
University of British Columbia
McGill University; University of Arizona

Completed

Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock

Septic Shock | Bacteremia | Severe Sepsis

Canada, United States
Medical Centre Leeuwarden

Completed

The Effect of Ketanserin on the Microcirculation in Sepsis

Septic Shock | Severe Sepsis

Netherlands
Chang Gung Memorial Hospital

Unknown

Application of Biomarkers Change to Predict Outcome of Patient With Severe Sepsis (BCSS)

Sepsis | Septic Shock | Severe Sepsis | Multiple Organ Failure | Systemic Inflammatory Response Syndrome (SIRS)

Taiwan
Dr. Damon Scales
Canadian Institutes of Health Research (CIHR); Sunnybrook Research Institute

Recruiting

Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP) (PITSTOP)

Severe Sepsis or Septic Shock

Canada
Ospedale Santa Maria delle Croci

Recruiting

Short-course Antimicrobial Therapy in Sepsis

Sepsis | Septic Shock | Severe Sepsis | Infection

Italy
Dascena

Withdrawn

Gram Type Infection-Specific Sepsis Identification Using Machine Learning

Sepsis | Septic Shock | Severe Sepsis
Zhongnan Hospital

Unknown

Multiple Biomarkers in ICU Sepsis Patients

Sepsis | Septic Shock | AKI | Sepsis, Severe

China
University Hospital, Limoges
Vanderbilt University Medical Center; Revimmune

Terminated

Immune Reconstitution of Immunosuppressed Sepsis Patients (IRIS-7a)

Severe Sepsis With Septic Shock

France
International Centre for Diarrhoeal Disease Research...

Recruiting

Saving Lives by Early Detection and Treatment of Sepsis and Septic Shock by Point of Care Lactate Test in Adults (POCLactate)

Lactate Blood Increase | Severe Sepsis With Septic Shock

Bangladesh
Assistance Publique - Hôpitaux de Paris

Recruiting

Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit (PITAGORE)

Sepsis | Septic Shock

France
prof. dr. Frans B. Plötz
Dutch Society of Pediatrics; Zorgevaluatie Nederland; Care4Neo; everywhereIM

Recruiting

Safely Reduce Newborn Antibiotic Exposure With the Early-onset Sepsis Calculator

EOS | Early-Onset Sepsis, Neonatal

Netherlands
Siriraj Hospital

Not yet recruiting

Early Intravenous Hydrocortisone in Sepsis

Shock, Septic | Sepsis Severe

Thailand
Hospices Civils de Lyon

Recruiting

Observed Pharmacokinetic of Piperacillin/Tazobactam Compared to Amikacin in ICU (OPTIMA)

Sepsis | Septic Shock | Sepsis Syndrome

France
Brigham and Women's Hospital

Completed

Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis

Severe Sepsis or Septic Shock

United States
Rhode Island Hospital

Recruiting

Assessment for Implementation Methods in Sepsis (AIMS)

Septic Shock | Sepsis Severe

United States
Dascena
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Baystate Health; Cape... and other collaborators

Recruiting

Machine Learning Sepsis Alert Notification Using Clinical Data (HindSight P2)

Sepsis | Septic Shock | Severe Sepsis

United States
Research & Diagnostic Antibodies
National Institute of General Medical Sciences (NIGMS)

Terminated

Plasma Inducible Nitric Oxide Synthase (iNOS) Assay and Sepsis Study (PliNOSa® Test)

Sepsis | Septic Shock | Severe Sepsis
King Abdul Aziz Specialist Hospital

Completed

Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation

Septic Shock | ARDS

Saudi Arabia
Dascena
University of California, San Francisco

Withdrawn

Subpopulation-Specific Sepsis Identification Using Machine Learning

Sepsis | Septic Shock | Severe Sepsis
Dascena
University of California, San Francisco

Withdrawn

RCT of Sepsis Machine Learning Algorithm

Sepsis | Septic Shock | Severe Sepsis
Dascena
Cabell Huntington Hospital

Completed

Predictive algoRithm for EValuation and Intervention in SEpsis (PREVISE)

Sepsis | Septic Shock | Severe Sepsis

United States
University of Florida
University of Mississippi Medical Center

Completed

The Role of Dysfunctional HDL in Severe Sepsis

Sepsis | Septic Shock | Severe Sepsis

United States
Sirius Genomics Inc.

Unknown

Pharmacogenomic Biomarker Study for Recombinant Human Activated Protein C Treatment in Severe Sepsis

Septic Shock | Severe Sepsis

United States, Canada, France, United Kingdom
University of Athens

Completed

Clarithromycin as Immunomodulator for the Management of Sepsis

Sepsis | Septic Shock | Severe Sepsis

Greece
Chinese Septic Shock Network

Completed

Strategy of Early Improvement of Tissue Oxygenation Decrease the Mortality of Severe Sepsis and Septic Shock

Shock, Septic

China
Universidad de Guanajuato
University Medical Center Groningen

Unknown

Mortality Due to Septic Shock Associated With Thrombocytopenia

Septic Shock | Thrombocytopenia | Sepsis Bacterial

Mexico
Anders Perner
Rigshospitalet, Denmark; University of Copenhagen; B. Braun Melsungen AG; Copenhagen...

Completed

Scandinavian Starch for Severe Sepsis/Septic Shock Trial (6S)

Septic Shock | Severe Sepsis

Denmark, Norway, Finland, Iceland
Rennes University Hospital

Terminated

Community Acquired Sepsis Cohort (CASC)

Septic Shock | Severe Septic Syndrome

France
Center for Sepsis Control and Care, Germany
Center for Clinical Studies, University Hospital Jena, Germany; Dept. of Microbiology... and other collaborators

Completed

(1,3)-β-D-glucan Based Diagnosis of Invasive Candida Infection in Sepsis (CandiSep)

Septic Shock | Severe Sepsis

Germany
The Miriam Hospital

Recruiting

De-resuscitation Informed by Ultrasound for Patients With Sepsis (DRI-US)

Sepsis | Septic Shock | Sepsis, Severe | Volume Overload

United States
Region Örebro County

Unknown

Quantification of Bacterial DNA in Sepsis

Sepsis | Septic Shock | Sepsis Bacterial

Sweden
Duke University
Fogarty International Center of the National Institute of Health; Moi University

Completed

Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western Kenya

Sepsis | Septic Shock | Severe Sepsis

Kenya
Brno University Hospital

Unknown

Early Identification of Sepsis in Children

Sepsis | Shock, Septic | SIRS | Sepsis, Severe

Czechia
Chang Gung Memorial Hospital

Unknown

Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe Sepsis (SIRCSS)

Sepsis | Septic Shock | Severe Sepsis | Multiple Organ Failure | Systemic Inflammatory Response Syndrome (SIRS)

Taiwan
Henry Ford Health System
Beckman Coulter, Inc.

Active, not recruiting

Monocyte Distribution Width (MDW) in the General Population of Emergency Department Patients With and Without Bacteremia

Sepsis | Septic Shock | Bacteremia | Severe Sepsis | Emergency Departments | Continuity of Patient Care | Bacteremia Sepsis

United States
Jinnah Postgraduate Medical Centre

Recruiting

Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality (MUNI-SEP)

Septic Shock | Severe Sepsis | MODS

Pakistan
Southeast University, China

Enrolling by invitation

Effect of Immunophenotype on Prognosis of Sepsis

Sepsis | Septic Shock | Sepsis Syndrome

China
National Institute of General Medical Sciences...

Unknown

Protocol-driven Hemodynamic Support for Patients With Septic Shock

Sepsis | Shock, Septic | Severe Sepsis

United States
Hospital General de Ciudad Real
University of Castilla-La Mancha

Terminated

Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension (HYSATESS-p)

Septic Shock | Sepsis-associated Hypotension

Spain
Policlinico Hospital
Eli Lilly and Company

Completed

Effect of Hyperglycemia in PAI-1 Activity and the Relationship With Outcome in Severe Sepsis and Septic Shock

Septic Shock | Severe Sepsis

Italy
Eisai Inc.

Completed

A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis

Sepsis | Shock, Septic | Infection | Sepsis Syndrome | Septicemia

United States

Clinical Trials on Sepsis

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