Clinical Trials on Severe Coronary Artery Disease

Total 12768 results

Spirocor

Terminated

SPIROCOR Coronary Outcome by Respiratory Stress Examination (SCORE)

Severe Coronary Artery Disease (S-CAD)

United States
Suzhou Zhonghui Medical Technology Co., Ltd.

Not yet recruiting

Clinical Trial of T-wave™ Coronary Lithotripsy Catheter System

Moderate to Severe Calcified Coronary Artery Stenosis
Saint Thomas Health

Withdrawn

RANOLAZINE STUDY: Speckle Tracking Derived Myocardial Strain

Severe Coronary Artery Disease | Ischaemic Myocardial Dysfunction

United States
Alexandria University

Not yet recruiting

Regional Blocks for CABG Artery Bypass Graft Surgery

Analgesia After Coronary Artery Bypass Graft Surgery
University of Leipzig
Heart Center Leipzig - University Hospital

Terminated

Chronic Inflammatory Activation in Fat Tissue: An Atherogenic Factor in Severe Coronary Artery Disease (KFO)

Obesity | Impaired Glucose Tolerance | Severe Coronary Artery Disease

Germany
Amsterdam UMC, location VUmc

Recruiting

Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease (VIADUCT)

Graft Failure | Coronary Artery Disease Progression | Recurrent Angina After Coronary Artery Bypass Graft

Netherlands
San Luigi Gonzaga Hospital

Recruiting

Outcomes After PCI of the Aneurysmatic Right Coronary Artery (RIGHT-MARE)

Coronary Disease | STEMI | Coronary Artery Ectasia | Right Coronary Artery Occlusion | Right Coronary Artery Stenosis

Spain, Italy
Fundación EPIC

Active, not recruiting

Concordance Between FFR and iFR for the Assessment of Intermediate Lesions in the Left Main Coronary Artery. A Prospective Validation of a Default Value for iFR (iLITRO)

Coronary Artery Disease | Left Main Coronary Artery Disease | Left Main Coronary Artery Stenosis | Restenosis, Coronary

Spain
Abbott Medical Devices

Completed

ABSORB FIRST is a Registry Designed to Evaluate the Safety and Performance of Absorb Bioresorbable Vascular Scaffold (Absorb BVS) Used in Real-world Patients.

Coronary Artery Disease | Coronary Disease | Coronary Occlusion | Chronic Total Occlusion of Coronary Artery | Coronary Restenosis | Coronary Artery Stenosis | Coronary Artery Restenosis

Belgium
Elixir Medical Corporation
Istituto Clinico Humanitas

Active, not recruiting

DYNAMX Bioadaptor ImplanTation for the trEatment of Complex Coronary Lesions (DYNAMITE)

Coronary Artery Disease | Chronic Total Occlusion of Coronary Artery | Multi Vessel Coronary Artery Disease | Bifurcation of Coronary Artery | Long Lesions Coronary Artery Disease

Italy
IGLESIAS Juan Fernando
University of Bern

Not yet recruiting

P2Y12 Inhibitor-based Single Antiplatelet Therapy After a Short DAPT vs. Conventional DAPT Following PCI With a Polymer-free Drug-coated Stent for Unprotected Left Main Coronary Artery Disease (ULTRA-LM) (ULTRA-LM)

Left Main Coronary Artery Stenosis

Switzerland
Segeberger Kliniken GmbH

Completed

The Comparison of Strategies to PREPARE Severely CALCified Coronary Lesions Trial (PREPARE-CALC) (PREPARE-CALC)

Coronary Atherosclerosis Due to Severely Calcified Coronary Lesion

Germany
Abbott Medical Devices

Completed

EXecutive RCT: Evaluating XIENCE V® in a Multi Vessel Disease (EXecutive)

Coronary Artery Disease | Coronary Disease | Coronary Artery Stenosis | Coronary Artery Restenosis

Italy
Abbott Medical Devices

Completed

EXecutive Registry: Evaluating XIENCE V® in a Multi Vessel Disease (EXecutive)

Coronary Artery Disease | Coronary Disease | Coronary Artery Stenosis | Coronary Artery Restenosis

Italy
Barts & The London NHS Trust
Imperial College London; Brunel University

Not yet recruiting

Multisensor Array for the Localisation of Coronary Artery Stenosis (MALCAS) (MALCAS)

CORONARY ARTERY DISEASE
Fundación EPIC

Recruiting

ANGiographic Evaluation of Left Main Coronary Artery INtErvention (ANGELINE)

Coronary Artery Disease | Coronary Disease | Coronary Occlusion | Left Main Coronary Artery Disease | Coronary Artery Stenosis

Spain
Peking Union Medical College Hospital

Recruiting

Efficacy and Safety of Comprehensive Treatment in Patients With IR-CAD: a Self-controlled Cohort Study

Coronary Artery Disease | Inflammation | Coronary Artery Disease Progression | Coronary Artery Stenosis | Coronary Artery Restenosis | Inflammatory Disease | Inflammation Vascular

China
Peking Union Medical College Hospital

Not yet recruiting

Disease Characteristics of IR-CAD: a Case-control Study

Coronary Artery Disease | Inflammation | Coronary Artery Disease Progression | Coronary Artery Stenosis | Coronary Artery Restenosis | Inflammatory Disease | Inflammation Vascular

China
National Institutes of Health Clinical Center (CC)
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Gadofosveset Trisodium for Heart Imaging Studies

Coronary Arteriosclerosis | Coronary Artery Disease (CAD) | Obstructive Coronary Artery Disease

United States
Concept Medical Inc.
Cardiovascular Research Foundation, New York

Not yet recruiting

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels (MAGICAL-SV)

Cardiovascular Diseases | Coronary Artery Disease | Native Coronary Artery Stenosis
Medical University of Silesia

Completed

PCI vs. CABG in UPLM-ISR (LM-DRAGON)

Left Main Coronary Artery Disease | Restenosis, Coronary | PTCA Left Main Artery Complications

Poland, Italy
China National Center for Cardiovascular Diseases

Recruiting

Functional Diagnostic Accuracy of Ultrasonic Flow Ratio in Assessment of Left Main Coronary Artery Stenosis (FUNCTION II)

Left Main Coronary Artery Disease

China
Johns Hopkins University
American Heart Association; Apple Inc.

Recruiting

Impact of a Corrie Cardiac Rehabilitation Program (mTECH-Rehab)

Myocardial Infarction | Myocardial Ischemia | Coronary Artery Disease | Valve Heart Disease | Coronary Artery Occlusion | Bypass Graft Occlusion | Coronary Artery Stenosis Stent

United States
Eisai Inc.
PPD

Completed

Comparison of AQUAVAN® Injection to DISOPRIVAN® Injectable Emulsion for Anesthesia During Coronary Artery Surgery

Coronary Artery Bypass Surgery | Ischemic Coronary Artery Disease
Johns Hopkins University

Recruiting

PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography] (PET; CT)

Coronary Artery Disease | Atherosclerosis | Coronary Atherosclerosis of Native Coronary Artery

United States
ECRI bv
GE Healthcare; HeartFlow, Inc.

Completed

SYNTAX III REVOLUTION Trial: A Randomized Study Investigating the Use of CT Scan and Angiography of the Heart to Help the Doctors Decide Which Method is the Best to Improve Blood Supply to the Heart in Patients With Complex Coronary Artery Disease (SYNTAX III)

Heart Diseases | Cardiovascular Diseases | Multivessel Coronary Artery Disease | Coronary Artery Diseases

Belgium, France, Germany, Italy, Switzerland
Parc de Salut Mar

Active, not recruiting

Microvascular Coronary Resistance and Absolute Coronary FLOW in Patients With Percutaneous Intervention of a Chronic Total Occlusion (FLOW-CTO)

Chronic Total Occlusion of Coronary Artery | Coronary; Ischemic | Coronary Microvascular Dysfunction | Microvascular Coronary Artery Disease

Spain
Guangzhou University of Chinese Medicine
First Affiliated Hospital, Sun Yat-Sen University; Shanghai 10th People's Hospital and other collaborators

Completed

Effect of Chinese Traditional Medicine for Post Revascularization Treatment of Coronary Artery Disease

Acute Coronary Syndrome | Percutaneous Coronary Artery Intervention | Coronary Artery Bypass Graft
Abbott Medical Devices

Completed

XIENCE V: SPIRIT WOMEN

Myocardial Ischemia | Coronary Artery Disease | Coronary Arteriosclerosis | Stent Thrombosis | Vascular Disease | Coronary Artery Stenosis | Total Coronary Occlusion | Coronary Artery Restenosis

France, Italy, Norway, China, Spain, Germany, United Kingdom, Switzerland, Israel, Denmark, Belgium, Austria, Poland, Australia, Portugal, Argentina, Brazil, Hungary, Latvia, Netherlands, India, Greece, Malaysia, Russian Federation, South... and more
Helios Health Institute GmbH
Heart Center Leipzig - University Hospital

Recruiting

Comparison of Vessel-FFR Versus FFR in Intermediate Coronary Stenoses (LIPSIASTRATEGY)

Coronary Artery Disease | Coronary Artery Stenoses

Germany
Seung-Jung Park
CardioVascular Research Foundation, Korea

Recruiting

Evaluation of Effectiveness and Safety of Hybrid Coronary Revascularization (HCR registry)

Coronary Stenosis | Coronary Artery Bypass Grafting | Coronary Artery Disease Progression | Percutaneous Coronary Revascularization

Korea, Republic of
Chonnam National University Hospital

Recruiting

Timing of FFR-guided PCI for Non-IRA in NSTEMI and MVD (OPTION-NSTEMI)

Myocardial Infarction, Acute | Multi-Vessel Coronary Artery Stenosis | Multi Vessel Coronary Artery Disease

Korea, Republic of
Abbott Medical Devices

Completed

XIENCE V: SPIRIT WOMEN Sub-study

Myocardial Ischemia | Coronary Artery Disease | Coronary Arteriosclerosis | Stent Thrombosis | Vascular Disease | Coronary Artery Stenosis | Total Coronary Occlusion | Coronary Artery Restenosis

Italy, Norway, Switzerland, Denmark, Spain, Poland, Belgium, Argentina, Austria, Brazil, France, Germany, Hungary, Latvia, Netherlands
Insight Lifetech Co., Ltd.
Shanghai Zhongshan Hospital; Chinese PLA General Hospital; The First Affiliated... and other collaborators

Completed

Clinical Evaluation of A New High-speed and High-resolution Intravascular Ultrasound System (NEW-IVUS)

Coronary Artery Disease | Percutaneous Coronary Intervention | Chronic Total Occlusion of Coronary Artery | Left Main Coronary Artery Disease

China
China National Center for Cardiovascular Diseases
Peking University International Hospital; Beijing Shijitan Hospital, Capital... and other collaborators

Not yet recruiting

Complete Revascularization Via Inferior Part-sternotomy

Multivessel Coronary Artery Disease | Coronary Artery Bypass Grafting | Complete Revascularization
Abbott Medical Devices
Bristol-Myers Squibb; Eli Lilly and Company; Daiichi Sankyo, Inc.; Baim Institute...

Completed

XIENCE V® USA Dual Antiplatelet Therapy (DAPT) Cohort (XVU-AV DAPT)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Chronic Total Occlusion of Coronary Artery | Coronary Restenosis | Vascular Disease | Coronary Artery Stenosis

United States
Tryton Medical, Inc.

Completed

Prospective, Single Blind, Rand Controlled Study to Evaluate the Safety & Effectness of Tryton Side Branch Stent Used With DES Treatmt of de Novo Bifurcation Lesions in MB & SB in Native Coronaries (TRYTON)

Coronary Atherosclerosis of Native Coronary Artery | Bifurcation Lesions: de Novo Lesions of the Main and Side Branch of Native Coronary Artery

United States
Abbott Medical Devices

Completed

SPIRIT III Clinical Trial of the XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)

Myocardial Ischemia | Coronary Artery Disease | Stent Thrombosis | Vascular Disease | Coronary Artery Stenosis | Stents | Total Coronary Occlusion | Coronary Artery Restenosis

United States
National Cerebral and Cardiovascular Center

Recruiting

REASSURE-NIRS Registry (REASSURENIRS)

Lipid-Rich Atherosclerosis of Coronary Artery

Japan
Abbott Medical Devices

Completed

EXCEL Clinical Trial (EXCEL)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Stent Thrombosis | Coronary Restenosis | Chronic Coronary Occlusion | Vascular Disease | Coronary Artery Stenosis | Unprotected Left Main Coronary Artery Disease

United States
St George's, University of London
St George's University Hospitals NHS Foundation Trust; Shockwave Medical, Inc.

Unknown

Intravascular Balloon Lithotripsy in Left Main Stem Percutaneous Coronary Intervention

Left Main Coronary Artery Disease | Coronary Artery Calcification

United Kingdom
Azienda Ospedaliera Città della Salute e della...

Recruiting

Ultrathin DES in Complex PCI Scenarios: the ULTRA a Multicenter Study (ULTRA)

Coronary Artery Disease | Chronic Total Occlusion of Coronary Artery | Left Main Coronary Artery Disease | Coronary Stenosis | Stent Restenosis

Italy
Örebro County Council

Completed

Five-year Patency of No-touch Saphenous Vein Grafts in On-pump Versus Clamp-less Off-pump Coronary Artery Bypass Surgery

Coronary Artery Stenoses
Abbott Medical Devices

Completed

EXCEL Clinical Trial (Universal Registry) (EXCEL)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Left Main Coronary Artery Disease | Stent Thrombosis | Coronary Restenosis | Chronic Coronary Occlusion | Vascular Disease | Coronary Artery Stenosis

United States
Rambam Health Care Campus

Completed

In-stent Restenosis in Patients With Patent Previous Bare Metal Stent

In-stent Coronary Artery Restenosis

Israel
Yonsei University

Completed

Combination Effects of High-dose Statin and Trimetazidine on Patients With Aspirin Mono Antiplatelet Therapy 12-months After Coronary Artery Bypass Surgery

Coronary Artery

Korea, Republic of
Biotronik (Beijing) Medical Device Ltd.
Biotronik AG

Enrolling by invitation

BIOFLOW-china Post-marketing Study (BIOTRONIK)

Native Coronary Artery Stenosis | In-Stent Stenosis (Restenosis) of Coronary Artery Stent

China
Sohag University

Recruiting

Study of Percutaneous Coronary Intervention in Left Main Coronary Artery Disease in Patients With Acute Coronary Syndrome at Sohag University Hospitals

Left Main Coronary Artery Disease With Acute Coronary Syndrome

Egypt
Ospedale Santa Maria Goretti

Withdrawn

Prognostic Assessment of Different Pattern of Bifurcation Restenosis (LATINA)

In-stent Coronary Artery Restenosis

Italy
MINVASYS
European Cardiovascular Research Center

Completed

Safety and Efficacy Study of the DANUBIO Paclitaxel Eluting Balloon in In-Stent Restenosis Lesions (DEBREST) (DEBREST)

In-stent Coronary Artery Restenosis

France

Clinical Trials on Severe Coronary Artery Disease

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