Clinical Trials on Soft Tissue Tumors

Total 64996 results

National Cancer Institute (NCI)

Completed

A Pilot Study for the Treatment of Patients With Metastatic and High Risk Sarcomas and Primitive Neuroectodermal Tumors

Sarcoma | Neuroepithelioma | Osteosarcoma | Neuroectodermal Tumor, Primitive | Sarcoma, Ewing's

United States
Immunolight, LLC

Recruiting

X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma

Advanced Solid Tumor Cancer

United States
National Cancer Institute (NCI)

Completed

Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma

Rhabdomyosarcoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Childhood Angiosarcoma | Childhood Epithelioid Sarcoma | Childhood... and other conditions

United States, Canada
National Cancer Institute (NCI)

Completed

SU5416 in Treating Patients With Advanced, Metastatic, or Recurrent Soft Tissue Sarcomas

Sarcoma | Gastrointestinal Stromal Tumor

United States
Swiss Group for Clinical Cancer Research
Immunophotonics, Inc.

Recruiting

Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Advanced Solid Tumors.

Advanced Solid Tumors

Switzerland
Ohio State University Comprehensive Cancer Center

Recruiting

An Electronic Health Record (EHR)-Based Comprehensive Bone and Soft Tissue Tumor Registry

Neoplasms, Connective and Soft Tissue | Bone Neoplasms

United States
European Organisation for Research and Treatment...

Terminated

Chemotherapy in Treating Patients With Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor

Sarcoma

United Kingdom
Novartis Pharmaceuticals

Completed

Imatinib Mesylate in Patients With Refractory Desmoplastic Small Round Cell Tumors

Refractory Desmoplastic Small Round Cell Tumors

Italy
PharmaMar

Completed

Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy

Ewing's Sarcoma | Primitive Neuroectodermal Tumor (PNET) | Askin's Tumor of the Chest Wall | Extraosseous Ewing's Sarcoma (EOE)

France, United States, Italy
National Cancer Institute (NCI)

Completed

Ixabepilone in Treating Young Patients With Refractory Solid Tumors

Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Wilms Tumor and Other Childhood Kidney Tumors | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Ewing Sarcoma... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Collecting and Storing Biological Samples From Patients With Ewing Sarcoma

Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Askin Tumor

United States, Canada, Puerto Rico, Australia, New Zealand, Switzerland
AB Science

Completed

Masitinib in Locally Advanced/Metastatic Gastro-intestinal Stromal Tumour (GIST)

Gastro-intestinal Stromal Tumours

France
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Radiation Therapy in Treating Patients With Ewing's Sarcoma, Peripheral Primitive Neuroectodermal Tumor, or Rhabdomyosarcoma

Sarcoma

United States
National Cancer Institute (NCI)

Completed

IMC-A12 in Treating Young Patients With Relapsed or Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor or Other Solid Tumor

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
Plexxikon

Terminated

A Study of PLX73086 in Advanced Solid Tumors and Locally Advanced or Refractory Tenosynovial Giant Cell Tumor

Solid Tumors | Tenosynovial Giant Cell Tumor | Synovitis, Pigmented Villonodular

United States
Celgene

Completed

Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors

Melanoma | Sarcoma, Soft Tissue | Cancer | Fibrosarcoma | Neuroblastoma | Osteogenic Sarcoma | Rhabdomyosarcoma | Neoplasm | Malignant Melanoma | Tumors | Histiocytoma | Dermatofibrosarcoma | Sarcoma, Ewing's | Neoplasia | Ewing's Sarcoma | Ewing's Tumor | Sarcomas, Epitheliod | Sarcoma, Spindle Cell | Clinical Oncology | Oncology,... and other conditions

United States, Canada, Spain, France, United Kingdom, Italy, Switzerland
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination With Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor (PRIME)

Advanced Solid Tumor | Advanced Soft-tissue Sarcoma | Advanced L-sarcomas | Other Advanced Sarcomas | Localized Soft-tissue Sarcoma

Spain
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Descriptive Study of a Cohort of Orbital Solitary Fibrous Tumors (TFS-ORB)

Orbital Tumor

France
National Cancer Institute (NCI)

Completed

Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma

Gastrointestinal Stromal Tumor | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Adult Rhabdomyosarcoma | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal... and other conditions
AB Science

Completed

Masitinib in Patients With Gastro-Intestinal Stromal Tumour Resistant to Imatinib

Gastro Intestinal Stromal Tumor

France
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Mesenchymal Chondrosarcoma | Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Malignant Peripheral Nerve Sheath Tumor | PEComa | Synovial Sarcoma | Epithelioid Sarcoma | Alveolar Soft Part Sarcoma | Undifferentiated High Grade Pleomorphic... and other conditions

United States, Canada, Puerto Rico
European Organisation for Research and Treatment...

Completed

Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma

Sarcoma | Gastrointestinal Stromal Tumor

France, Netherlands, Belgium, United Kingdom, Germany
Institut Bergonié
French Sarcoma Group

Recruiting

Patterns of Care and Outcomes of Patients With METAstatic Gastrointestinal Stromal Tumors (METAGIST) (METAGIST)

Gastro Intestinal Stromal Tumor

France
University Medical Center Groningen
Dutch Cancer Society

Recruiting

GIST: Assessment of Tumor Mutations and TKI Plasma Exposure

Gastro-intestinal Stromal Tumor

Netherlands
Shanghai JMT-Bio Inc.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone

Giant Cell Tumor of Bone

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Zoledronic Acid-loaded Bone Cement as a Local Adjuvant Therapy for Giant Cell Bone Tumor After Intralesional Curettage

Giant Cell Tumor of Bone

China
Shanghai JMT-Bio Inc.

Completed

A Real-world Study on Patients of Unresectable Giant Cell Tumor of Bone

Giant Cell Tumor of Bone

China
Hebei Medical University Third Hospital

Unknown

Characteristics and Mechanism of Denosumab-treated Giant Cell Tumor of Bone (D-Gct)

Giant Cell Tumor of Bone

China
Leiden University Medical Center

Terminated

Adjuvant Zoledronic Acid in High Risk Giant Cell Tumour of Bone (GCT) (HR-GCT)

Giant Cell Tumor of Bone | Osteoclastoma

Netherlands, Belgium
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

A Study of Safety and Efficacy of Sirolimus for Injection (Albumin-bound) in Patients With Advanced Malignant Perivascular Epithelioid Cell Tumor (PEComa)

Advanced Malignant Perivascular Epithelioid Cell Tumor (PEComa)

China
Nantes University Hospital

Terminated

Study of the Effect of Zoledronate on Local Recurrence After Surgical Treatment of Giant Cell Tumors of Bone Zométa (Zometa)

Giant Cell Tumors of Bone

France
Amgen

Recruiting

Study of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the Bone

Giant Cell Tumor of Bone

Taiwan, China
Shanghai JMT-Bio Inc.

Active, not recruiting

Efficacy and Safety of JMT103 in Patients With Giant Cell Tumor of Bone

Giant Cell Tumor of Bone

China
Daiichi Sankyo, Inc.

Completed

Exatecan Mesylate in Treating Patients With Ewing's Sarcoma, Primitive Neuroectodermal Tumor, or Desmoplastic Small Round Cell Tumor

Sarcoma

United States, Canada
Amgen

Completed

Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004

Giant Cell Tumor of Bone

Australia, France, United States, Spain, Italy, Poland, Sweden, United Kingdom
Istituto Ortopedico Rizzoli

Completed

Giant Cell Tumor of the Bone in Young Patients

Giant Cell Tumor of Bone

Italy
Istituto Ortopedico Rizzoli

Completed

Giant Cell Tumor of the Extremities Treated With Surgery and/or Medical Treatment (GCTLIMBS)

Giant Cell Tumor of Bone
Y-mAbs Therapeutics

Terminated

Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor Cancers

Osteosarcoma | Neuroblastoma | Other Solid Tumor Cancers

United States
University Hospital, Strasbourg, France

Recruiting

Cryoablation for Advanced and Refractory Desmoid Tumors (CARDT)

Desmoid Tumors

France
University Hospital, Strasbourg, France

Completed

Evaluation of the Cryodestruction of Non Abdominopelvic Desmoid Tumors in Patients Progressing Despite Medical Treatment (CRYODESMO01)

Desmoid Tumors

France
Boehringer Ingelheim

Completed

Trial of Afatinib in Pediatric Tumours

Neuroectodermal Tumors | Rhabdomyosarcoma

United States, Spain, Canada, Germany, Italy, United Kingdom, Australia, Austria, Denmark, Faroe Islands, France, Netherlands
Ascentage Pharma Group Inc.
HealthQuest Pharma Inc.

Recruiting

A Study of HQP1351 in Patients With GIST or Other Solid Tumors

Solid Tumor, Adult | Gastrointestinal Stromal Tumor (GIST)

China
St. Jude Children's Research Hospital
Pfizer; Ipsen

Recruiting

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Refractory Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Peripheral Primitive Neuroectodermal Tumor | Recurrent Rhabdoid Tumor | Recurrent... and other conditions

United States, Canada
Ann & Robert H Lurie Children's Hospital of Chicago
National Cancer Institute (NCI); Northwestern University

Completed

Intensity-Modulated Radiation Therapy in Treating Younger Patients With Lung Metastases

Unspecified Childhood Solid Tumor, Protocol Specific | Unspecified Adult Solid Tumor, Protocol Specific | Lung Metastases | Recurrent Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Recurrent Wilms Tumor and Other Childhood Kidney Tumors | Previously... and other conditions

United States
Eli Lilly and Company

Completed

A Five-Tier, Open-Label Study of IMC-A12 in Advanced Sarcoma

Leiomyosarcoma | Rhabdomyosarcoma | Synovial Sarcoma | Ewing's Sarcoma /Peripheral Neuroectodermal Tumor (PNET) | Adipocytic Sarcoma

United States, Germany, Poland, Belgium, Spain, France, Netherlands
Plexxikon

Terminated

Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors

Solid Tumor | Tenosynovial Giant Cell Tumor | Tumors of Any Histology With Activating Trk (NTRK) Point or NTRK Fusion Mutations

United States
Masonic Cancer Center, University of Minnesota

Completed

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Soft Tissue Sarcoma | Medulloblastoma | Retinoblastoma | Rhabdomyosarcoma | Hepatoblastoma | Primary Malignant Brain Neoplasms | CNS Tumors | Germ Cell Tumors | Ewing's Family Tumors | Renal Tumors | Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET) | Atypical Teratoid/Rhabdoid Tumor (AT/RT)

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Diagnostic Study of Tumor Characteristics in Patients With Ewing's Sarcoma

Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Study of Vinorelbine and Cyclofosfamide Among Patients With Refractory Tumours or in Relapse

Neoplasms, Connective and Soft Tissue | Osteosarcomas | Medulloblastomas | Rhabdomyosarcomas | Ewing Tumor | Neuroblastomas

France
Sarcoma Alliance for Research through Collaboration
Bristol-Myers Squibb

Completed

Trial of Dasatinib in Advanced Sarcomas

Chondrosarcoma | Chordoma | Hemangiopericytoma | Rhabdomyosarcoma | Sarcoma, Alveolar Soft Part | Epithelioid Sarcoma | Gastrointestinal Stromal Tumor (GIST) | Giant Cell Tumor of Bone | Sarcoma, Ewing's | Malignant Peripheral Nerve Sheath Tumors

United States

Clinical Trials on Soft Tissue Tumors

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