Clinical Trials on Stage IV Colon Cancer With Resectable Liver Metastases

Total 535 results

Dana-Farber Cancer Institute
National Cancer Institute (NCI); Pharmavite LLC

Recruiting

Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases

Stage, Colon Cancer | Stage I-III Colon Cancer | Stage IV Colon Cancer With Resectable Liver Metastases

United States
Amal Therapeutics
Boehringer Ingelheim

Active, not recruiting

Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (KISIMA-01)

Metastatic Colorectal Cancer | Colorectal Cancer | Liver Metastasis Colon Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer | MSS

United States, Belgium, Switzerland, Germany
City of Hope Medical Center

Completed

Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
National Cancer Institute (NCI)

Terminated

Neoadjuvant and Adjuvant Capecitabine and Oxaliplatin in Treating Patients With Resectable Liver Metastases Secondary to Colorectal Cancer

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Cancer Institute and Hospital, Chinese Academy...

Unknown

Short Course Radiotherapy Combined With Chemotherapy in Stage IV Rectal Cancer With Resectable Liver Metastases

Stage IV Rectal Cancer, Liver Metastasis, Resectable

China
National Institutes of Health Clinical Center (CC)

Completed

Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Amsterdam UMC, location VUmc
Angiodynamics, Inc.

Not yet recruiting

COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases (COLDFIRE-III)

Colorectal Cancer | Liver Metastases | Liver Metastasis Colon Cancer | Unresectable Solid Tumor
Heidelberg University
University Hospital Tuebingen; SLK Kliniken Heilbronn GmbH

Unknown

TACE With Drug Eluting Beads Loaded With Doxorubicin in Liver Metastases From Melanoma Patients

Stage IV Melanoma Patients With Unresectable Liver Metastases

Germany
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

Liver Metastases | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Stanford University
National Cancer Institute (NCI); Philips Healthcare

Completed

Pilot 3D Contrast-Enhanced Ultrasound Imaging to Predict Treatment Response in Liver Metastases

Colon Cancer | Liver Metastases

United States
University of Manchester
Manchester University NHS Foundation Trust; The Christie NHS Foundation Trust; Perspect... and other collaborators

Unknown

Colorectal Liver Metastases: Novel Assessment Tools for Technical Resectability (CoNoR)

Cancer | Colorectal Cancer | Liver Metastasis Colon Cancer | Cancer Metastatic

United Kingdom
National Cancer Institute (NCI)

Terminated

Cetuximab and/or Dasatinib in Patients With Colorectal Cancer and Liver Metastases That Can Be Removed by Surgery

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Liver Metastases | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC... and other conditions

United States
Lawson Health Research Institute
Bayer

Recruiting

Gadoxetate Abbreviated MRI in Metastatic Colorectal Cancer

Liver Metastasis Colon Cancer

Canada
AllVascular

Recruiting

Study of Intra-Arterial Oxaliplatin Plus Capecitabine to Treat Liver Metastases From Colorectal Cancer (SYS-CAPLIOX)

Liver Metastasis Colon Cancer

Australia
Leiden University Medical Center

Not yet recruiting

Fluorescence-guided Resection Of Colorectal Liver Metastases Using SGM-101 and Indocyanine GREEN (FOCUS GREEN)

Colorectal Cancer | Image | Liver Metastasis Colon Cancer
Peking University Cancer Hospital & Institute
Zhejiang Cancer Hospital; West China Hospital; The First Affiliated Hospital... and other collaborators

Completed

Perioperative Chemotherapy Plus Cetuximab Versus Chemotherapy Alone for High Risk Resectable Colorectal Liver Metastasis (PARECEC)

Metastasis | Colorectal Cancer Stage IV

China
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Recruiting

Liver Transplantation for Non-Resectable Colorectal Liver Metastasis

Colorectal Cancer | Liver Metastasis Colon Cancer

Italy
University of Wisconsin, Madison

Withdrawn

Living Donor Liver Transplantation for CRC Liver Metastases

Liver Metastasis Colon Cancer

United States
Odense University Hospital

Unknown

Treatment Response Evaluation in Patients With Non-resectable Colorectal Liver Metastases A Feasibility Study (TRICOMA)

Liver Metastasis Colon Cancer

Denmark
Zhu Xu

Unknown

Oxaliplatin and Raltitrexed Treatment of Colorectal Cancer With Liver Metastases

Colon Cancer Liver Metastasis

China
University of Milan

Completed

Contrast-Enhanced Intraoperative Ultrasound During Liver Surgery for Colorectal Cancer Liver Metastases (CEIOUSCLM)

Colon Cancer Liver Metastasis

Italy
Seoul National University Hospital

Recruiting

LT for Unresectable Colorectal Liver Metastasis

Liver Metastasis Colon Cancer

Korea, Republic of
University of Aarhus
Aarhus University Hospital; Rigshospitalet, Denmark

Recruiting

Improving Survival of COlorectal LIver Metastases by RFA-mediated Immunostimulation (ISCOLIM)

Liver Metastasis Colon Cancer

Denmark
Celyad Oncology SA

Terminated

Hepatic Transarterial Administrations of NKR-2 in Patients With Unresectable Liver Metastases From Colorectal Cancer (LINK)

Colon Cancer Liver Metastasis

Belgium
Rabin Medical Center

Unknown

Treatment With Hepatic Arterial Infusion of Oxaliplatin in Combination With Systemic FOLFIRI Chemotherapy and Bevacuzimab in Patients With Liver-only Colorectal Liver Metastases (CRLM): Conversion to Complete Resection in Patients With Initially Inoperable Liver-only CRLM.

Liver Metastasis Colon Cancer

Israel
Celyad Oncology SA

Unknown

Dose Escalation and Dose Expansion Phase I Study to Assess the Safety and Clinical Activity of Multiple Doses of NKR-2 Administered Concurrently With FOLFOX in Colorectal Cancer With Potentially Resectable Liver Metastases (SHRINK)

Colon Cancer Liver Metastasis

Belgium
Giammaria Fiorentini

Unknown

TACE Associated to Systemic Bevacizumab for the Treatment of Refractory Liver Metastases From Colorectal Cancer (EMBOBEVA)

Liver Metastasis Colon Cancer

Italy
Tianjin Medical University Cancer Institute and...

Unknown

Irinotecan-Eluting Bead (DEBIRI) for Patients With Liver Metastases From Colorectal Cancer (DEBIRI-CRLM)

Colon Cancer Liver Metastasis

China
Fudan University

Unknown

Safety of TACE With Oxaliplatin, Irinotecan and Raltitrexed for Refractory Colorectal Cancer Liver Metastasis

Colon Cancer Liver Metastasis

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer

Recurrent Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 and other conditions

United States
Amsterdam UMC, location VUmc

Recruiting

COLLISION XL: Unresectable Colorectal Liver Metastases (3-5cm): Stereotactic Body Radiotherapy vs. Microwave Ablation (COLLISION-XL)

Colorectal Cancer Metastatic | Liver Metastasis Colon Cancer

Netherlands
Chandrikha Chandrasekharan
AstraZeneca; Biocompatibles UK Ltd

Suspended

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer (iRE-C)

Metastatic Colorectal Cancer | Colorectal Neoplasms | Rectal Cancer | Colon Cancer | Colorectal Cancer Metastatic | Liver Metastases | Colo-rectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Liver Metastasis Colon Cancer

United States
Sun Yat-sen University

Recruiting

Sonazoid-enhanced Ultrasound for the Detection of Colorectal Liver Metastases Less Than 2 cm

Liver Metastasis Colon Cancer

China
Oncology Institute of Vojvodina

Recruiting

Prospective Clinical Study of Intraoperative Assessment of Resection Margin of Colo-Rectal Cancer Liver Metastases

Liver Metastasis Colon Cancer

Serbia
University of Regensburg
University of Halle Medical Faculty

Withdrawn

Perioperative Treatment of Resectable Liver Metastases (PERIMAX)

Colon Cancer Liver Metastasis
International Group of Endovascular Oncology

Completed

Observational Study on Second Line Treatment of Liver Metastases With DEBIRI and Cetuximab (TACETUX)

Colon Cancer Liver Metastasis

Italy
Medical University of Warsaw
Medical Research Agency, Poland

Not yet recruiting

TANGO-LIVER Three Arm Nuclear Growth Observation in Liver Surgery (TANGO-LIVER)

Liver Neoplasms | Liver Metastases | Liver Cancer | Liver Metastasis Colon Cancer

Poland
First Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

TACE Plus HAIC Combined With Regorafenib for Liver Metastasis of Colorectal Cancer Refractory to Standard Treatment Regimens

Liver Metastasis Colon Cancer

China
University of Leeds
National Cancer Institute (NCI); Massachusetts General Hospital; Massachusetts... and other collaborators

Recruiting

Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases

Colon Cancer Liver Metastasis

United Kingdom
M.D. Anderson Cancer Center
Bristol-Myers Squibb; Syntrix Biosystems, Inc.

Recruiting

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer

Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage... and other conditions

United States
Azienda Ospedaliero-Universitaria di Modena

Recruiting

LDLT in Non Resectable Colo-rectal Cancer Liver Metastasis (LIVERMORE)

Liver Metastasis Colon Cancer | Colon Adenocarcinoma

Italy
Memorial Sloan Kettering Cancer Center

Recruiting

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

Colorectal Cancer | Colon Cancer | Liver Metastasis Colon Cancer | Adenocarcinoma of the Rectum | Colon Cancer Liver Metastasis | Adenocarcinoma of the Colon

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation

Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IV Colon Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Unresectable Colon Adenocarcinoma | Unresectable Rectal Adenocarcinoma

United States, Puerto Rico
Institut Mutualiste Montsouris
Ministry of Health, France; National Cancer Institute, France

Recruiting

Effect of the Laparoscopic Approach in Reducing Postoperative Severe Complications Following Hepatectomy for Colorectal Liver Metastases (METALAP)

Postoperative Complications | Liver Metastasis Colon Cancer

France
Leiden University Medical Center
Philips Healthcare; European Commission

Recruiting

Prospective Cohort Study on Thermal Ablation of Malignant Liver Tumors (A-IMAGIO)

Hepatocellular Carcinoma | Liver Metastases | Liver Cancer | Liver Metastasis Colon Cancer

Netherlands
McGill University Health Centre/Research Institute...

Recruiting

Application of High-dose Insulin Therapy to Improve Liver Function and Regeneration

Liver Dysfunction | Liver Metastasis Colon Cancer | Liver Regeneration

Canada
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Terminated

Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial

Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Colon Cancer AJCC... and other conditions

United States
Fox Chase Cancer Center

Terminated

Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Liver Metastases | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States

Clinical Trials on Stage IV Colon Cancer With Resectable Liver Metastases

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