Clinical Trials on Substance Dependence

Total 9091 results

VA Office of Research and Development

Completed

LINK: Aftercare Monitoring Project

Alcohol Dependence | Drug Dependence

United States
Milton S. Hershey Medical Center

Completed

Penn State TXT2Quit Study

Nicotine Dependence, Cigarettes

United States
University Hospital, Gentofte, Copenhagen

Completed

FGF21 and Its Role in Alcohol Dependence (AlcoDep)

Alcohol Abuse or Dependence

Denmark
NYU Langone Health
National Institute on Drug Abuse (NIDA)

Completed

Aprepitant Effects in Intravenous Heroin Dependence

Opioid Dependence

United States
Albert Einstein College of Medicine

Completed

Varenicline for Co-occurring Cannabis and Tobacco Use

Cannabis Dependence | Tobacco Dependence
Yale University

Completed

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

Nicotine Dependence, Other Tobacco Product

United States
Yale University
National Institute on Drug Abuse (NIDA); US Department of Veterans Affairs

Completed

Efficacy of Varenicline in Methadone-Stabilized Cocaine Users

Nicotine Dependence | Cocaine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Gabapentin Treatment of Benzodiazepine Abuse in Methadone Maintenance Patients

Benzodiazepine Dependence | Opioid Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Opiate Dependence: Combined Naltrexone/Behavior Therapy - 1

Heroin Dependence

United States
Semmelweis University

Completed

Acute Oral Effects of Heated Tobacco Products

Nicotine Dependence, Cigarettes

Hungary
University of Minnesota

Withdrawn

Progesterone and Atomoxetine for Cocaine Cessation

Nicotine Dependence | Cocaine Dependence

United States
VA Office of Research and Development

Completed

Impact of Group Motivational Interviewing and In-Home-Messaging-Devices for Dually Diagnosed Veterans (GMI-IHMDs)

Alcohol Dependence | Dual Diagnosis | Drug Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Memantine as a Supplement to Naltrexone in Treating Heroin Dependence (NAMHS)

Heroin Dependence | Opioid Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Behavioral Naltrexone Therapy for Promoting Adherence to Oral Naltrexone vs Extended Release Injectable Depot Naltrexone (Depot-BNT)

Heroin Dependence | Opiate Dependence

United States
National Institute on Drug Abuse (NIDA)
New York MDRU

Completed

Buprenorphine/Naloxone in the Treatment of Heroin Dependence - 14

Substance-Related Disorders | Opioid Dependence

United States
Brown University
National Institute on Drug Abuse (NIDA)

Completed

Impact of Nicotine Reduction on Adolescent Cigarette Use, Alternative Tobacco Use, and Harm From Tobacco (SIREN)

Nicotine Dependence, Cigarettes, Uncomplicated

United States
University of Arkansas
National Institute on Drug Abuse (NIDA); Baylor College of Medicine

Completed

Doxazosin for Psychostimulant Dependence

Methamphetamine or Cocaine Dependence

United States
State University of New York - Upstate Medical...
US Department of Veterans Affairs

Terminated

Long-Acting Injectable Naltrexone Treatment of Alcohol Dependence in Primary Care vs. in Specialized Chemical Dependence Treatment: A Pilot Trial

Alcohol Dependence | Veterans

United States
Northwell Health
National Institute of Mental Health (NIMH)

Withdrawn

Improving Outcomes in Psychosis Associated With Substance Use Using Aripiprazole (SIP)

Substance Abuse | Substance Dependence

United States
Chestnut Health Systems
National Institute on Drug Abuse (NIDA)

Completed

Adolescent Outpatient and Continuing Care Study (AOCCS)

Substance Abuse | Substance Dependence

United States
University of California, Los Angeles

Completed

Buprenorphine/Naloxone Versus Clonidine for Inpatient Opiate Detoxification - 1

Heroin Dependence | Substance Withdrawal Syndrome | Morphine Dependence

United States
University of California, Los Angeles

Completed

Buprenorphine/Naloxone Versus Clonidine for Outpatient Opiate Detoxification - 1

Heroin Dependence | Substance Withdrawal Syndrome | Morphine Dependence

United States
Sorlandet Hospital HF

Completed

Treatment of Polydrug-Using Opiate Dependents During Withdrawal

Substance Withdrawal Syndrome | Opiate Dependence | Drug Dependence

Norway
Duke University
National Institute on Drug Abuse (NIDA)

Recruiting

Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

Nicotine Dependence, Cigarettes | Adverse Childhood Experiences

United States
University of Virginia
National Institute on Alcohol Abuse and Alcoholism (NIAAA); M.D. Anderson Cancer... and other collaborators

Active, not recruiting

New Treatment for Alcohol and Nicotine Dependence

Alcohol Dependence | Nicotine Dependence

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Human Behavioral Pharmacology Laboratory (HBPL) Study of Varenicline's Impact on Cocaine and Alcohol Craving

Alcohol Dependence | Cocaine Dependence

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

HBPL Study of the Impact of the NK1 Antagonist Aprepitant

Alcohol Dependence | Cocaine Dependence

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

10 Days of Theta Burst Stimulation as a Tool to Treat Cocaine Dependence

Alcohol Dependence | Cocaine Dependence

United States
VA Office of Research and Development

Completed

Topiramate to Aid Smoking Cessation in Alcohol Dependent Men

Alcohol Dependence | Nicotine Dependence

United States
National Development and Research Institutes, Inc.

Unknown

Applying Web Technology to Buprenorphine Treatment

Adult Opioid-Dependence

United States
Milton S. Hershey Medical Center

Recruiting

Buprenorphine Induction for Fentanyl Dependent Opioid Users

Opioid Dependence Fentanyl

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Nalrexone Facilitated Discontinuation of Buprenorphine

Stable Opioid Dependence

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence

Alcoholism | Cocaine Dependence

United States
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Effect of Varenicline on Reactivity to Smoking and Drinking Cues

Alcohol Dependence | Tobacco Dependence

Canada
National Taiwan University Hospital

Unknown

Combination of Psychosocial Intervention and Slow Prosecutions for the Treatment of Methamphetamine Abuse/Dependence

Methamphetamine Dependence | Methamphetamine Abuse | Amphetamine Dependence | Amphetamine Abuse

Taiwan
Boston University Charles River Campus
National Institute on Drug Abuse (NIDA); Massachusetts General Hospital

Completed

Stress, Distress Intolerance, and Drug Dependence

Substance Dependence

United States
GlaxoSmithKline

Completed

GSK618334 Repeat Dose Study

Substance Dependence

United Kingdom
GlaxoSmithKline

Withdrawn

Relapse Prevention Study in Newly Abstinent Smokers

Substance Dependence

United States
University of California, San Francisco
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

A Pilot Clinical Trial of Varenicline as a Treatment for Alcohol Dependence

Substance Dependence

United States
Click Therapeutics, Inc.

Completed

Clinical Trial of Smoking Cessation Mobile Phone Program

Substance Use Disorder | Drug Addiction | Tobacco Dependence | Drug Dependence | Nicotine Addiction

United States
Centre for Addiction and Mental Health
American Foundation for Suicide Prevention

Completed

Efficacy of Cognitive Bias Modification in Residential Treatment for Addiction

Substance Dependence

Canada
University of South Florida

Unknown

Distress Tolerance Treatment for Substance Users

Substance Dependence

United States
GlaxoSmithKline

Completed

To Investigate If Single Doses Of GSK618334 Are Safe And To Investigate Blood Levels Of GSK618334

Substance Dependence

United Kingdom
GlaxoSmithKline

Completed

A Study To Investigate The Safety, Tolerability And Blood Levels Of GSK598809

Substance Dependence

Germany
GlaxoSmithKline

Completed

A Healthy Volunteer Study to Investigate the Relative Bioavailability of Two Forms of GSK598809 Capsules.

Substance Dependence

United Kingdom
GlaxoSmithKline

Completed

A Human Volunteer Study Investigating Single Oral Doses of GSK598809 in Otherwise Healthy Smokers

Substance Dependence

Germany
GlaxoSmithKline

Completed

EtOH Interaction Study

Substance Dependence

Netherlands
Douglas Mental Health University Institute

Completed

Memory Reconsolidation Blockade for Treating Drug Addiction

Substance Dependence

Canada
University of Nevada, Reno

Not yet recruiting

Feasibility and Acceptability of Switching to E-cigarettes Among Cigarette Smokers Engaged in SUD Treatment

Tobacco Dependence Caused by Cigarettes

United States
Semmelweis University

Completed

Epidemiology and Acute Oral Effects Electronic Cigarette

Nicotine Dependence, Cigarettes

Clinical Trials on Substance Dependence

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Denmark

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations