Clinical Trials on TTN

Total 79 results

Rigshospitalet, Denmark

Completed

Moderate Intensity Training in Patients With Truncating Genetic Variants in TTN.

Cardiomyopathies | TTN | Truncation Mutation

Denmark
Ramsay Générale de Santé
Dr Béatrice Daoud

Unknown

Benefit of Tin Filter in Regards to Image Quality and Radiation Dose in CT Scan Study of Pulmonary Parenchyma

Tin X Ray | Pulmonary Parenchyma

France
University of Minnesota

Not yet recruiting

mGlide-Care: A Partnership With Caregivers

HTN
The Hospital for Sick Children

Not yet recruiting

Isoleucine, Leucine, Valine and Tryptophan Requirements in TPN Fed Neonates

Stable Neonates Receiving Total Parenteral Nutrition (TPN)

Brazil
The Hospital for Sick Children

Recruiting

Phenylalanine, Methionine and Histidine Requirements in TPN Fed Neonates

Stable Neonates | Receiving Total Parenteral Nutrition (TPN)

Canada
Hadassah Medical Organization

Unknown

Mapping and Stimulating the Limbic Areas of the Subthalamic Nucleus

Mapping the Limbic STN Using Neuronal Responses

Israel
Assiut University

Completed

Measuring Serum Level of Total L Carnitine in HIE and TTN (HIELcarnitine)

Compare Between the Serum Level of Lcarnitine in HIE Cases and TTN
Hanmi Pharmaceutical Company Limited
Seoul National University Bundang Hospital

Completed

Pharmacokinetic Interaction Between HGP0904, HGP0608 and HGP1405

Hypertension(HTN)

Korea, Republic of
Servier Russia

Not yet recruiting

Evaluation of the Antihypertensive effectIveness, Tolerability, and Adherence With Amlodipine/ Indapamide/ Perindopril Triple Single-pill Combination in Hypertensive Patients Without Concomitant Antihypertensive Therapy (TRIPTYCH) (TRIPTYCH)

Arterial Hypertension | HTN
Alnylam Pharmaceuticals

Completed

Phase 2 Study to Evaluate ALN-TTRSC (Revusiran) in Patients With Transthyretin (TTR) Cardiac Amyloidosis

TTR-mediated Amyloidosis

United States, United Kingdom
Pfizer

Completed

Safety And Pharmacokinetic Assessment Of Orally Administered Tafamidis In Healthy Volunteers

TTR Cardiomyopathy

Singapore
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Actions to Decrease Disparities in Risk and Engage in Shared Support for Blood Pressure Control (ADDRESS-BP) in Blacks

Hypertension (HTN)
Quantum Genomics SA
PRA Health Sciences

Terminated

Randomized Study of Extended Treatment With Firibastat in Treatment-Resistant Hypertension (REFRESH) (REFRESH)

Hypertension (HTN)

United States, Canada
Mayo Clinic

Completed

Long-term Monitoring of Patients With Cardiac Amyloidosis With Implantable Event Monitors

TTR Cardiac Amyloidosis

United States
Pfizer

Completed

A Study To Determine Any Effect Of Tafamidis On Electrocardiographic Intervals, Specifically The Rate Corrected QT Interval (QTc)

TTR Cardiomyopathy

United States, Singapore, Belgium
Alnylam Pharmaceuticals

Completed

Safety and Tolerability of Patisiran (ALN-TTR02) in Transthyretin (TTR) Amyloidosis

TTR-mediated Amyloidosis

Portugal, Spain, Sweden, Brazil, United States, France, Germany
IRCCS Policlinico S. Matteo

Completed

A Study of Doxycycline and Tauroursodeoxycholic Acid (Doxy/TUDCA) Plus Standard Supportive Therapy Versus Standard Supportive Therapy Alone in Cardiac Amyloidosis Caused by Transthyretin

TTR Cardiac Amyloidosis

Italy
Alnylam Pharmaceuticals

Completed

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

TTR-mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects

TTR-mediated Amyloidosis

United Kingdom
Groupe Hospitalier du Havre

Not yet recruiting

Transcutaneous Electrical Nerve Stimulation During Exercise in Patients With COPD (proTENS)

Physical Activity | Rehabilitation | COPD | TEN

France
Alnylam Pharmaceuticals

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of ALN-TTR02 in Japanese Healthy Volunteers

Transthyretin (TTR)-Mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Completed

The Study of ALN-TTR02 (Patisiran) for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Who Have Already Been Treated With ALN-TTR02 (Patisiran)

TTR-mediated Amyloidosis

Portugal, Sweden, Brazil, United States, France, Spain, Germany
Alnylam Pharmaceuticals

Completed

A Extension Study to Evaluate Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Cardiac Amyloidosis

TTR-mediated Amyloidosis

United States, Canada, United Kingdom
Pfizer

Completed

Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy

ATTR-CM | TTR-CM

United States
Pfizer

Completed

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy (ATTR-ACT)

Transthyretin (TTR) Amyloid Cardiomyopathy

United States, Spain, Czechia, Canada, Belgium, Netherlands, Germany, Japan, France, United Kingdom, Brazil, Italy, Sweden
Danish Headache Center

Completed

The Diameter of the Middle Cerebral Artery Measured With Magnetic Resonance Angiography

Migraine | Headache | Healthy Volunteers | MR-Angiography | GTN | Middle Cerebral Artery
Unity Health Toronto

Recruiting

Use of Gentle Synchronized Negative Pressure in Helping Babies Breathe (Neovest)

Respiratory Distress Syndrome | RDS of Prematurity | TTN | Respiratory Distress, Newborn

Canada
Pfizer

Completed

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Transthyretin (TTR) Amyloid Cardiomyopathy

United States, Taiwan, Canada, Belgium, Australia, Czechia, Sweden, Spain, Italy, Hong Kong, Germany, Netherlands, United Kingdom, France, Japan, Argentina, Brazil
Cairo University

Unknown

Safety and Efficacy Evaluation of TPN in Preterm Neonates in NICU of Cairo University Children Hospital

TPN in Preterm

Egypt
Kaplan Medical Center

Unknown

Radioisotope Scintigraphy to Establish Incidence of Cardiac Amyloidosis Among Patients With Otherwise Unexplained Cardiac Disease

Cardiac TTR Amyloidosis
Tzu-Ting Huang

Completed

Non-pharmacological Interventions on Cognitive Functions in Older People With Mild Cognitive Impairment

Physical Activity | Mild Cognitive Impairment | Cognitive Rehabilitation | TTM
Erebouni Medical Center
Fisher and Paykel Healthcare

Completed

Effect of Cannula Size on Oxygen Saturation During Nasal High Flow Therapy in Newborns

TTN | RDS - Infants

Armenia
Assiut University

Completed

Predictors of Left Ventricular Hypertrophy in Hypertensive Patients in Assiut Governorate

Hypertrophy, Left Ventricular | HTN

Egypt
Servier Russia

Completed

Description of the Effectiveness, Safety, Tolerability and Adherence to Amlodipine/Atorvastatin/Perindopril Single Pill Combination Treatment in Patients With Arterial Hypertension and Dyslipidemia (TARGET) (TARGET)

Arterial Hypertension | HTN

Russian Federation
Pfizer

Recruiting

Vyndaqel Capsules Special Investigation (ATTR-CM)

Transthyretin (TTR) Amyloid Cardiomyopathy

Japan
The First Affiliated Hospital of Xiamen University

Recruiting

Pulmonary Vein Isolation (PVI) Combined With Renal Denervation (RDN) in Atrial Fibrillation (AF) and Hypertension (HTN)

AF - Atrial Fibrillation | HTN-Hypertension

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Decision Aids in Improving Knowledge in Patients With Newly Diagnosed Prostate Cancer

Stage I Prostate Cancer | Stage II Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer | PSA Level Five to Ten | PSA Level Less Than Five | PSA Level Ten to Fifty

United States
Pfizer

Completed

Burden of Disease Study In Patients With Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) orTransthyretin Cardiomyopathy (TTR-CM) And Caregivers

Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) | Transthyretin Cardiomyopathy (TTR-CM) | Familial Amyloid Cardiomyopathy | Senile Systemic Amyloidosis (SSA)
Medical University of Warsaw
Jagiellonian University; University of Ottawa; Pomeranian Medical University... and other collaborators

Recruiting

the Inhaled β2-adrenergic Receptor Agonist for Transient Tachypnoea of the Newborn (the REFSAL Trial) (REFSAL)

Respiratory Failure | TTN | PPHN

Poland
Icahn School of Medicine at Mount Sinai

Completed

Lung Ultrasound to Diagnose Transient Tachypnea of the Newborn (TTN) Versus Respiratory Distress Syndrome (RDS) in Neonates

Respiratory Distress Syndrome | Transient Tachypnea of the Newborn | RDS | TTN

United States
Massachusetts Eye and Ear Infirmary
London School of Hygiene and Tropical Medicine; University of Pennsylvania; The... and other collaborators

Active, not recruiting

FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial (FLAME)

Eye Diseases | Eyelid Diseases | Trichiasis | Trachomatous Trichiasis (TT) | Trachomatous

Ethiopia
Medstar Health Research Institute
Indian Institute of Technology Kanpur

Recruiting

The Effect of Personal Protective Aids on Hypertension and Diabetes in People Exposed to High Levels of Air Pollution

Diabetes Mellitus | Pollution; Exposure | HTN

India
Oslo University Hospital

Completed

Prophylactic Fenestration of the Peritoneum in Kidney Transplantation (PROFFEN)

Incidence of Symptomatic Lymphocele After Kidney Transplantation | Prevalence of Perirenal Fluid Collections at One, Five and Ten Weeks

Norway
Hospices Civils de Lyon

Completed

Avelumab in Chemo-resistant Gestational Trophoblastic Neoplasias (TROPHIMMUN)

Gestational Trophoblastic Neoplasias (GTN)

France
Tianjin Medical University Cancer Institute and...

Unknown

A Single Arm Study of Brain Metastasis in Patients With HER2-positive Breast Cancer

TTP

China
A.O. Ospedale Papa Giovanni XXIII
Associazione Italiana Parkinsoniani (AIP)- Sezione Bergamo

Unknown

Prospective Study to Compare Results of STN-DBS Between Early Treated and Late-treated PD Patient (DeBraStE)

Parkinson's Disease | Deep Brain Stimulation | DBS | STN

Italy
Bloodworks
University of Washington

Completed

A Pilot Study of N-acetylcysteine in Thrombotic Thrombocytopenia Purpura (NACinTTP)

Purpura, Thrombotic Thrombocytopenic | TTP

United States
Charles M Knudson

Recruiting

Biorepository and Registry for Plasma Exchange Patients

Antibody-mediated Rejection | CIDP | NMO Spectrum Disorder | TTP

United States
Hospices Civils de Lyon
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt...

Recruiting

Avelumab and Methotrexate in in Low-risk Gestational Trophoblastic Neoplasias as First Line Treatment (TROPHAMET)

Gestational Trophoblastic Neoplasias (GTN)

France
Baxalta now part of Shire
Takeda Development Center Americas, Inc.

Recruiting

A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)

Thrombotic Thrombocytopenic Purpura (TTP)

United States, Spain, Poland, Italy, Germany, France, Switzerland, Austria, Japan, United Kingdom

Clinical Trials on TTN

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