Clinical Trials on Tolerability

Total 92 results

National Center for Occupational Health and Infection...
VA Office of Research and Development

Completed

Assessment of Novel Respiratory Protective Devices in Healthcare

Tolerability | Comfort

United States
AstraZeneca

Completed

Study to Investigate Single Ascending Oral Doses of AZD5213 in Healthy Male and Non Fertile Female Subjects

Tolerability

United States
Jemincare

Recruiting

Safety, Tolerability of JMKX003002 in Phase 1 Study in Healthy Subjects

Safety and Tolerability

China
Island Pharmaceuticals
Beyond Drug Development

Completed

A Study to Evaluate the Safety of Fenretinide in Healthy Volunteers

Safety and Tolerability

Australia
Usona Institute

Completed

Pharmacokinetics, Safety, and Tolerability of Intramuscular 5-MeO-DMT in Healthy Volunteers

Pharmacokinetics | Tolerability | Safety

United States
Damian Pharma AG
University Hospital Inselspital, Berne; Covance; Foundation for Therapeutic Research...

Completed

DP13 SAD & MAD in Healthy Male Subjects

Safety and Tolerability

United Kingdom
AnaMar AB
Covance

Completed

Safety, Tolerability and Pharmacokinetics of AM1476 in Healthy Subjects

Tolerability | Safety

United Kingdom
Repros Therapeutics Inc.

Completed

A Dose Escalating Study to Determine the Tolerability and PK of a Single Dose of Androxal

Pharmacokinetics | Tolerability

United States
BioGaia AB

Completed

Study Evaluating the Safety and Tolerability of a Probioitc

Healthy Volunteers | Tolerability | Safety

Sweden
Sichuan Huiyu Pharmaceutical Co., Ltd

Recruiting

Phase 1/2 Study of HYP-2090PTSA in Patients With Advanced Solid Tumors Harboring KRAS Mutation

Efficacy | Tolerability | Safety

China
Jemincare
Zhejiang Hangyu Pharmaceutical Co., Ltd

Recruiting

Phase 1 Clinical Study of JMKX003142 Tablets

Safety and Tolerability

China
Yuejia Pharmaceuticals (USA), Inc.
Zhejiang Yuejia Pharmaceuticals Co., Ltd.

Completed

Single-Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of YJ001 in Healthy Volunteers

Safety and Tolerability

United States
MerLion Pharmaceuticals GmbH

Completed

Pharmacokinetic Profile in Plasma and Epithelial Lining Fluid of Finafloxacin

Safety and Tolerability

United States
Actelion

Completed

Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-128800 in Healthy Subjects

Safety and Tolerability

United Kingdom
Sun Yat-sen University

Completed

Tolerability and Pharmacokinetics of M2ES in the Treatment of Advanced Solid Tumor

Pharmacokinetics | Tolerability | Endostatin

China
4TEEN4 Pharmaceuticals GmbH

Recruiting

Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics/-Dynamics of AK1967 (Procizumab)

Safety and Tolerability

Netherlands
Alumis Inc

Completed

Multiple Dose Study to Determine Safety and Tolerability of ESK-001 in Healthy Participants

Safety and Tolerability

United States
RH Nanopharmaceuticals
Center for Bioequivalence Studies and Clinical Research

Completed

Phase 1 Clinical Trial of RHN-001 in Healthy Adult Volunteers

Pharmacokinetics | Tolerability | Safety

Pakistan
Gabather AB
Smerud Medical Research International AS

Completed

Study of Ascending Single Oral Dose of GT-002 in Healthy Volunteers (GAB-001)

Safety and Tolerability

Finland
Modus Therapeutics AB

Completed

Placebo-controlled Study to Determine the Safety and Tolerability of Subcutaneous Doses of Sevuparin

Safety and Tolerability

United States
Daiichi Sankyo, Inc.

Completed

Single Ascending Dose Study Using DS-1971 to Assess Safety, Tolerability, and Pharmacokinetics in Healthy Participants.

Pharmacokinetics | Tolerability | Safety

United Kingdom
Kowa Research Institute, Inc.

Completed

Study Comparing the Pharmacokinetics, Pharmacodynamics, and Safety of K-312 in Healthy Adult Volunteers

Safety and Tolerability

United States
AstraZeneca

Completed

Assessing the Safety and Tolerability of a Single IV Dose of AZD9742 in Healthy Elderly Male and Female Subjects

Healthy | Elderly | Tolerability

United States
SPARK Biopharma

Completed

SB17170 Phase1 Trial in Healthy Volunteer

Pharmacokinetics | Pharmacodynamics | Safety Issues | Tolerability

Korea, Republic of
Inje University

Completed

Efficacy, Safety and Tolerability of Split-dose of PEG Compared With NaP Solution for Colonoscopy Preparation: A Randomized, Controlled Trial (SPEN)

Bowel Preparation, Efficacy, Tolerability, Safety

Korea, Republic of
Shanghai Yao Yuan Biotechnology Ltd. (also known...

Recruiting

Evaluating the Safety, Tolerability, and Pharmacokinetics of DF-003 in Healthy Subjects

Healthy | Safety and Tolerability

United States
Nanjing Immunophage Biotech Co., Ltd

Recruiting

IPG7236 in Patients With Advanced Solid Tumors

Pharmacokinetics | Safety Issues | Tolerability

United States
Takeda

Terminated

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MLN3126 in Healthy Japanese and Non-Japanese Participants

Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

United States
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206

Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

Netherlands
e-Therapeutics PLC

Completed

Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects

Cancer | Pharmacokinetics | Tolerability | Safety

United Kingdom
AstraZeneca

Withdrawn

Phase I, Single Centre, Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD3043 (AZD3043)

Pharmacokinetics | Sedation | Tolerability | Safety
Cinclus Pharma Holding AB

Completed

Effect of Clarithromycin on PK of Linaprazan, Linaprazan on PK of Clarithromycin and Linaprazan on PK of Midazolam

Pharmacokinetics | Safety Issues | Tolerability | Drug Interaction

Sweden
Veralox Therapeutics

Completed

Phase I Study of VLX-1005 in Healthy Subjects

Safety and Tolerability in Healthy Volunteers

United States
Bioniz Therapeutics
Celerion

Completed

A Multiple-Dose Study of Intravenous BNZ132-1-40 in Healthy Adult Subjects

Safety and Tolerability in Healthy Subjects

United States
MerLion Pharmaceuticals GmbH

Completed

Effect of Age and Gender on the PK and Tolerability of Finafloxacin

Pharmacokinetic and Tolerability of Finafloxacin

United States
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD7503 in Healthy Participants

Pharmacokinetics | Healthy Participants | Tolerability | Safety

United States
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Oral Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-281959 / ACT-246475 in Healthy Male Subjects

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

France
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 After Single Ascending Doses to Healthy Males

Healthy Subjects | Pharmacokinetics | Tolerability | Safety

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Clinical Trial to Investigate Safety and Tolerability of ASP7962 in Healthy Humans

Tolerability | Safety | Pharmacokinetics of ASP7962

United Kingdom
Yiling Pharmaceutical Inc.

Completed

A Phase I Pharmacokinetics Study for KT07 Capsule

Pharmacokinetics | Healthy Adult Subjects | Safety and Tolerability

United States
Chattem, Inc.

Completed

Evaluation of Experimental Heat Patch

Tolerability | Adhesiveness | Dermal Irritation | Effects of Heat

United States
Galderma R&D

Completed

Safety and Efficacy of Lip Injections With Emervel Lips and Juvederm Ultra Smile

Local Tolerability After Lip Filler Injections

Germany
Laboratorios Sophia S.A de C.V.

Completed

Clinical Study for the Evaluation of Safety and Tolerability of PRO-172 Ophthalmic Solution+ (PRO-172)

Tolerability | Safety | Ocular Surface | Ocular Comfort

Mexico
Annexon, Inc.
Nucleus Network Ltd

Completed

A Single and Multiple Ascending Dose Study of ANX009 in Normal Healthy Volunteers (NHV)

Safety and Tolerability in Healthy Volunteers

Australia
Medigene AG

Terminated

TCR Modified T Cells MDG1011 in High Risk Myeloid and Lymphoid Neoplasms

Feasibility | Tolerability | Safety | Treatment Efficacy

Germany
Julie Dawson
Medical Research Council; University of East Anglia

Completed

CAVA: Electrode Pad Appraisal Trial (CEPAT)

Tolerability of Wear of Electrode Pads

United Kingdom
Annexon, Inc.

Terminated

Single Dose Study of ANX005 in Healthy Volunteers

Safety and Tolerability in Healthy Volunteers

Australia
Neuraly, Inc.

Completed

A Phase 1 Study to Assess the Safety of NLY01 in Healthy Subjects (NLY01-H1)

Safety and Tolerability in Healthy Volunteers

United States
Cinclus Pharma AG

Recruiting

A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan Glurate

GERD | Pharmacokinetics | Cardiodynamic ECG | Safety, and Tolerability

Sweden
Shanghai Junshi Bioscience Co., Ltd.

Unknown

Phase I Study of Comparing Single Dose JS005 (Recombinant Humanized Monoclonal Antibody Against IL-17A) With Placebo in Tolerability, Safety, Immunogenicity and Pharmacokinetic in Healthy Volunteers

Tolerability, Safety, Immunogenicity and Pharmacokinetic of JS005

China

Clinical Trials on Tolerability

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Armenia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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