Clinical Trials on Transplantation Immunology

Total 7464 results

Emory University

Recruiting

Immune Monitoring and Assay Development in Organ Transplant Recipients (IMP)

Organ Transplantation | Transplantation Immunology

United States
Astellas Pharma Inc
Astellas Pharma Taiwan, Inc.

Completed

A Randomized Study to Assess the Safety and Efficacy of Prograf vs Prograf-XL in de Novo Kidney Transplant Recipients

Kidney Transplantation | Transplantation Immunology | Host vs Graft Reaction

Taiwan
Astellas Pharma Inc
Astellas Pharma Taiwan, Inc.

Completed

A Randomized Study to Assess the Safety and Efficacy of Prograf vs Prograf-XL in de Novo Liver Transplant Recipients.

Liver Transplantation | Transplantation Immunology | Host vs Graft Reaction

Taiwan
University of Wisconsin, Madison

Completed

Glutamine Popsicles in Bone Marrow Transplant (BMT)/Hematopoietic Stem Cell Transplant (HSCT) Patients

Bone Marrow Transplantation | Hematopoietic Stem Cell Transplantion

United States
University of Giessen
Novartis; Astellas Pharma US, Inc.; German Cancer Research Center; Heidelberg University

Completed

Impact of Rituximab (RTx) Induction and Living Donation on Immunoregulation and Virus Control in Renal Transplantation

Kidney Transplantation | Immunology | Virus | Living Donors | Rituximab (RTx)

Germany
Astellas Pharma Europe Ltd.

Active, not recruiting

Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Intestine Transplantation

Belgium, Czechia, France, Germany, Italy, Poland, United Kingdom
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate FK778 in Kidney Transplant Patients

Kidney Transplantation | Renal Transplantation | Transplantation, Kidney | Grafting, Kidney | Transplantation, Renal

Belgium, Germany, Spain, Sweden, Italy, Switzerland, United Kingdom, Austria, France, Poland, Czech Republic, Netherlands
Astellas Pharma Europe Ltd.

Completed

A Study to Compare How the Body Absorbs and Processes Two Different Formulations of the Anti-rejection Medication Tacrolimus (Advagraf® or Prograf®) in Children Receiving an Organ Transplant, and How Safe and Effective They Are Over a Longer Period of Time

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Czechia, France, Italy, Poland, United Kingdom
The Hospital for Sick Children

Completed

Pharmacogenetic Trial of Tacrolimus After Pediatric Transplantation

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Canada
Astellas Pharma Europe Ltd.

Terminated

A Paediatric, Open, Follow up Study With Modigraf Examining Safety and Efficacy in de Novo Allograft Recipients (PROGRESSION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Astellas Pharma Europe Ltd.

Completed

Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Spain, Australia, France, Germany, Canada, Italy, United Kingdom, Belgium, South Africa, Switzerland, Sweden, United States, Austria, Brazil, Czechia, Denmark, Finland, Hungary, Ireland, Mexico, Netherlands, New Zealand, Poland
Astellas Pharma Europe Ltd.

Completed

A Study to Determine Pharmacokinetics of Children Receiving Modigraf (Tacrolimus Granules) Following Solid Organ Transplantation (OPTION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Astellas Pharma Inc

Completed

Study to Compare the Pharmacokinetics of Tacrolimus in Adult Transplant Recipients Treated With Advagraf® or Prograf®

Heart Transplantation | Lung Transplantation | Pancreas (Including SPK) Transplantation

France, United Kingdom, Taiwan, Belgium, Italy, Austria
Emory University

Completed

Quality of Life in Pediatric Transplant Recipients

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Heart-Lung Transplantation

United States
Novartis

Completed

Conversion Trial From Mycophenolate Mofetil (MMF) to Enteric-coated Mycophenolate Sodium (EC-MPS) in Stable Transplanted Patients Suffering From Gastrointestinal (GI) Adverse Events While on Mycophenolate Mofetil Therapy (MMF) Therapy

Liver Transplantation | Kidney Transplantation

Switzerland
University of Wisconsin, Madison

Terminated

Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant

Liver Transplantation | Kidney Transplantation

United States
Nantes University Hospital

Unknown

A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus Corticosteroids

Kidney Transplantation | Pancreas Transplantation

France
University Hospital, Gasthuisberg
Juvenile Diabetes Research Foundation; Fund for Scientific Research, Flanders...

Unknown

Insulin Secretory Capacity in Insulin-independent Pancreas-Kidney Recipients Compared to Controls

Kidney Transplantation | Pancreas Transplantation

Belgium
National Taiwan University Hospital

Unknown

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Treg Cell Therapy in Liver and Kidney Transplantation - Preclinical Validation of Batches of Treg Cells Amplified in Vitro (PRE-TREG)

Liver Transplantation | Kidney Transplantation

France
Astellas Pharma China, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of a Modigraf® Based Immunosuppression Regimen in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
Astellas Pharma China, Inc.

Completed

A Study of Modigraf® (Tacrolimus Granules) to Evaluate the Pharmacokinetics and Long-term Safety and Efficacy in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
University of Nebraska

Completed

Pre-operative Evaluation of Kidney & Pancreas Transplant Patients

Kidney Transplantation | Pancreas Transplantation

United States
Rennes University Hospital

Completed

Impact of P-gp, MRP2, ENT-1 and CNT3 on the Blood Concentration / Intra-PBMC Concentration of Tacrolimus (TRANS-TAC)

Liver Transplantation | Kidney Transplantation

France
Bristol-Myers Squibb

Completed

Pattern Of Use Of Belatacept In US Transplant Recipients

Kidney Transplantation: Transplantation, Kidney
Helsinki University Central Hospital
Tampere University Hospital

Completed

Immunogenicity of 13-valent Pneumococcal Conjugate Vaccine Compared to the Pneumococcal Polysaccharide Vaccine in Adult Kidney and Liver Transplant Patients (SOT13)

Liver Transplantation | Kidney Transplantation

Finland
National Taiwan University Hospital

Unknown

The Influence of ABCB1、CYP3A4、CYP3A5、POR Genetic Polymorphism and Other Factors on Tacrolimus Blood Concentration

Liver Transplantation | Kidney Transplantation

Taiwan
Astellas Pharma Inc

Completed

A Study to Demonstrate Safety and Efficacy of Advagraf in Patients Undergoing Kidney or Liver Transplantation in India

Liver Transplantation | Kidney Transplantation

India
University of Manchester
Manchester University NHS Foundation Trust

Unknown

CEUS in Kidney and Pancreas Transplantation

Kidney Transplantation | Pancreas Transplantation

United Kingdom
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Organ Transplantation Rehabilitation: Effect of Bedside Exercise Device and Activity Reinforcement

Liver Transplantation | Heart Transplantation

Taiwan
University of Oslo School of Pharmacy

Completed

Intracellular and Renal/Myocardial Tissue Concentrations of Cyclosporine A (CsA) and Rejection Frequency Following Transplantation

Heart Transplantation | Renal Transplantation

Norway
Novartis

Completed

Everolimus in a Cyclosporine Microemulsion-free Regimen Compared to a Low-dose Cyclosporine Microemulsion Regimen, in de Novo Kidney Transplant Patients (CERTES02)

Organ Transplantation, Renal Transplantation
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation

Terminated

Optimization of NULOJIX® Usage As A Means of Avoiding CNI and Steroids in Renal Transplantation

Kidney Transplantation | Renal Transplantation

United States
National Taiwan University Hospital

Unknown

The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Nantes University Hospital

Terminated

Protocol DIVAT-Uro

Kidney Transplantation | Pancreas-kidney Transplantation

France
Hospices Civils de Lyon

Completed

Bile Acids and Incretins in Pancreas Kidney Transplant Patients (ITABI)

Kidney Transplantation | Pancreas-kidney Transplantation

France
Washington University School of Medicine
National Marrow Donor Program; Predictive BioDiagnostics, LLC

Completed

Study for the Evaluation of a GVHD Negative Outcome Score (GNOS) in Matched Unrelated or Haploidentical Hematopoietic Stem Cell Transplant

Hematopoietic Stem Cell Transplantation | Stem Cell Transplantation, Hematopoietic | Transplantation, Hematopoietic Stem Cell

United States
University of North Carolina, Chapel Hill
Mallinckrodt

Withdrawn

Acthar for Treatment of Post-transplant FSGS

Kidney Transplantation | Renal Transplantation | FSGS

United States
Bristol-Myers Squibb

Completed

Study Comparing the Safety and Efficacy of Belatacept With That of Cyclosporine in Patients With a Transplanted Kidney

Kidney Transplantation | Graft Rejection | Renal Transplantation

United States
National Center for Complementary and Integrative...
National Cancer Institute (NCI)

Completed

The Effects of Music Therapy-Based Stress Reduction on Bone Marrow Transplant Recipients

Stem Cell Transplantation | Bone Marrow Transplantation

United States
University of Pittsburgh

Recruiting

Biomarkers in Transplant Recipients to Improve Outcomes

Bone Marrow Transplantation | Solid Organ Transplantation

United States
Johns Hopkins University

Completed

A Study of mDOT for Immunosuppressant Adherence in Solid Organ Transplant Recipients

Liver Transplantation | Medication Adherence | Kidney Transplantation

United States
Medical College of Wisconsin

Terminated

Quality of Life in Pediatric Transplant Patients

Liver Transplantation | Kidney Transplantation | Heart Transplantation

United States
University Hospital, Geneva

Recruiting

Precision Dosing of Busulfan in Children Undergoing HSCT (BuGenes01)

Allogeneic Hematopoietic Stem Cell Transplantation | Hematopoietic Stem Cell Transplantation | Autologous Hematopoietic Stem Cell Transplantation

Switzerland
Hospital Israelita Albert Einstein

Recruiting

Impact of Yoga and Gentle Massage Practices on Symptom Management in Patients Undergoing HSCT (Yoga)

Bone Marrow Transplantation | Hematopoietic Stem Cell Transplantation

Brazil
National Institute of Allergy and Infectious Diseases...
PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network (ITN)

Active, not recruiting

Tolerance by Engaging Antigen During Cellular Homeostasis (TEACH)

Kidney Transplantation | Renal Transplantation | Renal Transplant Recipient

United States
Genentech, Inc.
Pfizer; Novartis Pharmaceuticals; Mylan Pharmaceuticals Inc; Sandoz; Roxane Laboratories and other collaborators

Recruiting

The Mycophenolate Pregnancy Registry

Heart Transplantation, Kidney Transplantation, Liver Transplantation, Autoimmune Diseases

United States
Astellas Pharma Korea, Inc.

Completed

A Single Center, Open-label, Randomized, Pilot Study to Evaluate the Safety and Efficacy of a Tacrolimus Modified Release, ADVAGRAF®, Versus Tacrolimus Twice Daily, PROGRAF® in Stable Renal Recipients (SINGLE)

Kidney Transplantation | Renal Transplantation | Stable Renal Recipients

Korea, Republic of
Astellas Pharma Europe Ltd.

Completed

A Study to Compare the Finger Prick Whole Blood MITRA Assay Method With the Established Venepuncture Whole Blood Method for Quantitative Determination of Tacrolimus Blood Concentrations in Transplant Patients (MITRA)

Liver Transplantation | Kidney Transplantation

France, United Kingdom
Medical University of Vienna

Unknown

Sirolimus Based Immunosuppression for Patients Undergoing Kidney Transplantation in the Eurotransplant Senior Program (ESP)

Kidney Function After Transplantation | Outcome After Kidney Transplantation

Clinical Trials on Transplantation Immunology

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