Clinical Trials on Treatment naïve

Total 1921 results

Elizabeth Dudnik

Recruiting

Durvalumab (MEDI4736) Plus Platinum-based Chemotherapy in Advanced LCNEC: a Pilot Phase II Study

Patients With Advanced Treatment Naive LCNEC

Israel
Universitair Ziekenhuis Brussel

Terminated

Body Composition, Bone Health and Hormonal Status in HIV-1-infected Individuals (BONBO)

HIV-1 | Treatment-naïve

Belgium
AbbVie
Genentech, Inc.

Terminated

Study of ABT-199 (GDC-0199) in Combination With Azacitidine or Decitabine (Chemo Combo) in Subjects With Acute Myelogenous Leukemia (AML)

Acute Myelogenous Leukemia | Myelogenous Leukemia | Treatment Naive AML

United States, Australia, France, Germany
Biosensors Europe SA

Completed

BioFreedom FIM Clinical Trial.

Treatment Of Stenotic Lesions In Native Coronary Arteries.

Germany
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Extension Study of Hetrombopag in Severe Aplastic Anemia

Treatment-naive Severe Aplastic Anemia

China
Faculty Hospital Kralovske Vinohrady

Completed

Aneurysmorrhaphy of Vascular Access for Haemodialysis (AVAH)

Patients With an Aneurysm of Native Vascular Access Indicated for Surgical Treatment

Czechia
University of Pittsburgh

Terminated

Opioid Induced Loss of Local Anesthetic Potency in Patients Undergoing Total Knee Arthroplasty

Opioid Tolerance, Opioid Naive, Opioid Exposure

United States
George Washington University

Completed

Proficiency Based Robotics Training Curriculum: Skill Acquisition & Transferability of Skills to Live Porcine Models

Medical Students Naive to Surgical Robotics

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study to Evaluate the Tolerance and Efficacy of Mitoxantrone Hydrochloride Liposome Injection Combined With Cytarabine in Patients With Acute Myeloid Leukemia (AML)

Treatment-naive or Relapsed or Refractory Acute Myeloid Leukemia (AML)

China
Qurient Co., Ltd.

Completed

A Phase 2 Study to Evaluate Early Bactericidal Activity, Safety, Tolerability, and Pharmacokinetics of Multiple Oral Doses of Telacebec (Q203)

Treatment-naïve, Sputum Smear-positive Patients With Drug-sensitive Pulmonary TB

South Africa
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
Peking University People's Hospital

Completed

To Evaluate Efficacy and Safety in TG-2349 Combination With DAG181 (± Ribavirin) in HCV Genotype I Infected Patients

Cirrhosis | Chronic Hepatics C Virus (HCV) Genotype 1 | Non-Cirrhotic | Treatment naïve

China
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.

Completed

A Phase III Study to Evaluate Efficacy and Safety of TG-2349 in Combination With DAG181 and RBV for HCV Type I Patients

Cirrhosis | Chronic Hepatics C Virus (HCV) Genotype 1 | Non-Cirrhotic | Treatment naïve

China
ImevaX

Completed

Phase 1a/b Study on Safety of IMX101 in H. Pylori-negative and H. Pylori-infected Healthy Volunteers (IMX-02)

Helicobacter Pylori Infected Subjects | Helicobacter Pylori Naive Subjects

Germany
Centre Hospitalier Intercommunal Robert Ballanger

Unknown

To Evaluate Effectiveness and Safety of Containing Raltegravir in Naive HIV NON B or B Infected Patients (Ral'inNONB)

Evaluated | Non B Subtype | Naive Patients

France
Takeda

Completed

A Study of TAK-385 in Hormone Treatment-naïve Participants With Prostate Cancer

Hormone Treatment-naïve Participants With Prostate Cancer

Japan
National Institute of Allergy and Infectious Diseases...

Completed

Intensive Viral Dynamics Substudy of A5248

HIV Infections | Treatment Naive

United States
Shanghai Junshi Bioscience Co., Ltd.

Completed

A Study to Evaluate the Efficacy and Safety of Toripalimab or Placebo Combined With Chemotherapy in Treatment-naive Advanced NSCLC

Treatment-naive Advanced Non-small Cell Lung Cancer

China
University of Hohenheim
Universität Tübingen

Completed

Increasing the Oral Bioavailability of 6-prenylnaringenin by Micellar Solubilization

Safety of Native vs. Micellar 6-PN After Oral Intake | Pharmacokinetics of Native vs. Micellar 6-PN After Oral Intake | PBMC Activity After Native vs. Micellar 6-PN Oral Intake

Germany
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

A Randomized, Open-label, Multi-center, Phase III Study of Orelabrutinib in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) vs. R-CHOP Alone in Patients With Treatment-naїve Mantle Cell Lymphoma

Treatment-naїve Mantle Cell Lymphoma

China
Idera Pharmaceuticals, Inc.

Completed

Study of Combination Treatment With IMO-2125 and Ribavirin in Naïve Hepatitis C-infected, Genotype 1 Patients

Hepatitis C, Treatment Naïve, Genotype 1 Patients

France
Medinol Ltd.

Completed

NIRTRAKS Post-Market Study (NIRTRAKS) (NIRTRAKS)

de Novo Stenotic Lesions in Native Coronary Arteries

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Terminated

Liposomal Mitoxantrone Hydrochloride Injection,Cyclophosphamide, Vincristine and Prednisone in the Treatment of PTCL

Peripheral T Cell Lymphoma | Treatment-naïve

China
Biotronik AG

Completed

First in Man Trial - BIOSOLVE-I (BIOSOLVE-I)

de Novo Lesions in Native Coronary Arteries

Netherlands, Switzerland, Germany, Belgium
Janssen Infectious Diseases BVBA
Vertex Pharmaceuticals Incorporated

Completed

VX-950-C211 - A Dosing Regimen Study (Twice Daily Versus Every 8 Hours) of Telaprevir in Treatment-naïve Participants With Genotype 1 Chronic Hepatitis C Virus Infection

Genotype 1 Chronic Hepatitis C | Treatment Naive

United States, Australia, France, Poland, United Kingdom, Belgium, Germany, Spain, Sweden, Brazil, Austria, Ireland, Mexico
Fujian Cancer Hospital

Unknown

Opioid Titration With 12.5 ug/h Fentanyl Transdermal Patch vs Orally Morphine for Opioid-naïve Patients With Moderate Cancer Pain

Opioid, Moderate Cancer Pain, Transdermal Fentanyl, 12.5ug/h, Opioid-naive
Orbix Medical Ltd.

Unknown

Performance of OrbiSymm in Subjects Referred to Contra Lateral Breast Symmetrisation

Breast Asymmetry Between Native Breast and Reconstructed Breast

Italy
Tryton Medical, Inc.

Completed

Prospective, Single Blind, Rand Controlled Study to Evaluate the Safety & Effectness of Tryton Side Branch Stent Used With DES Treatmt of de Novo Bifurcation Lesions in MB & SB in Native Coronaries (TRYTON)

Coronary Atherosclerosis of Native Coronary Artery | Bifurcation Lesions: de Novo Lesions of the Main and Side Branch of Native Coronary Artery

United States
Psychiatric Centre Rigshospitalet
AstraZeneca

Terminated

KvaliMed - a Quality Project With Focus on Patients in Antipsychotic Treatment (KvaliMed)

Medical Treatment | Antipsychotic Treatment | Quality Assurance

Denmark
Vilniaus Implantologijos Centro (VIC) Klinika
Institut Straumann AG

Active, not recruiting

Immedaite vs Early Implant Placement in Aesthetic Area

Single Implant; Immediate Implant Treatment; Early Implant Treatment

Lithuania
Johns Hopkins University

Recruiting

PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography] (PET; CT)

Coronary Artery Disease | Atherosclerosis | Coronary Atherosclerosis of Native Coronary Artery

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective Investigation (BASILICA)

Native and Valve in Valve Aortic Valve Failure

United States
Zagazig University

Not yet recruiting

Novel Technique Lumber Spine Fusion: Unilateral Pedicular Screws Fixation Combined With Contralateral Interbody Cage

Treatment
Ajman University

Completed

An Analysis of Dental Treatments Rendered by Undergraduates at Ajman University to Patients From Fujairah, Uae

Treatment

United Arab Emirates
Nanjing University School of Medicine

Completed

Therapeutic Effect of Immunoadsorption for Patients With Lipoprotein Glomerulopathy

Treatment

China
Entheon Biomedical Corp.

Completed

Effect of Ketamine on Neurological Activity as Measured by Electroencephalogram (EEG)

Treatment-resistant Depression

United States
The University of Texas Health Science Center at...
Patient-Centered Outcomes Research Institute

Completed

Improving Transitional Care Experiences in Mental Health

Standard Treatment Versus Engagement Focused Treatment

United States
Eunice Kennedy Shriver National Institute of Child...

Withdrawn

Clonidine for Neurocognitive Sequelae

Treatment-Related Cancer

United States
Centre Hospitalier Universitaire Vaudois

Active, not recruiting

Analysis of the Modulation of the Tumor Microenvironment by MK-3475 (Pembrolizumab) Using a Systems Biology Approach (PEMSYS)

Metastatic Melanoma Naive to Immune Therapy in Metastatic Setting

Switzerland
All India Institute of Medical Sciences, Bhubaneswar

Recruiting

Dextromethorphan as an Augmentation Agent in Treatment-resistant Schizophrenia

Treatment Resistant Schizophrenia

India
Suzhou Puhe Pharmaceutical Technology Co., LTD

Recruiting

Assessing an Oral EGFR Inhibitor,YK-209A in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR

Treatment Side Effects | Treatment

China
Xuanwu Hospital, Beijing
Tianjin Anding Hospital; Ningcheng Center Hospital; Changning Mental Health Center and other collaborators

Not yet recruiting

Transcranial Alternating Current Stimulation for Treatment-Resistant Depression

Treatment-Resistant Depression
First Affiliated Hospital of Zhejiang University
Zhejiang University; Huzhou Third People's Hospital; Wenzhou Seventh People's... and other collaborators

Recruiting

Early Identification of TRD and Construction and Clinical Validation of NTBS Precision Technology

Treatment-Resistant Depression

China
Centre for Addiction and Mental Health

Recruiting

Does Psilocybin Require Psychedelic Effects to Treat Depression? (PSI-RIS)

Treatment-resistant Depression

Canada
Novartis Pharmaceuticals

Completed

Study of Efficacy, Safety, Tolerability and Pharmacokinetics of MIJ821 in Participants With Treatment- Resistant Depression (TRD)

Treatment-Resistant Depression

Spain, Japan, Poland, United States
VA Office of Research and Development
Mayo Clinic; University of Minnesota

Completed

Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression

Treatment-resistant Depression

United States
National Taiwan University Hospital
Shin Kong Wu Ho-Su Memorial Hospital

Completed

Psychosocial Characteristics and Non-pharmacological Intervention of Patients With Treatment-resistant Depression

Treatment-resistant Depression

Taiwan
Sidney Kimmel Cancer Center at Thomas Jefferson...
Novartis Pharmaceuticals

Terminated

Pasireotide (SOM230) With or Without Everolimus in Treating Patients With Hormone Resistant, Chemotherapy Naive Prostate Cancer

Prostate Cancer | Castrate Resistant Prostate Cancer | Chemotherapy Naive Prostate Cancer

United States
Changping Laboratory
Beijing HuiLongGuan Hospital

Recruiting

pBFS Guided High-dose rTMS Therapy for Treatment-Resistant Depression

Treatment-Resistant Depression

China
Central Institute of Mental Health, Mannheim
Charite University, Berlin, Germany; German Federal Ministry of Education and... and other collaborators

Active, not recruiting

Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression (EPIsoDE)

Treatment-resistant Depression

Germany
Janssen Research & Development, LLC

Completed

A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression (SUSTAIN-2)

Treatment-resistant Depression

United States, Australia, France, United Kingdom, Belgium, Germany, Taiwan, Spain, Argentina, Mexico, Poland, Bulgaria, Malaysia, South Africa, Turkey, Finland, Korea, Republic of, Brazil, Austria, Sweden, Lithuania

Clinical Trials on Treatment naïve

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