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Clinical Trials on Trypanosomiasis

Total 22 results

NCT02571062

Completed

Bioequivalence Study - Reference Clinical Fexinidazole Tablet Versus Proposed Market Formulation

Conditions: Trypanosomiasis, African
NCT01483170

Terminated

Multiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Human African Trypanosomiasis) Administered With a Loading Dose and With Food

Conditions: Trypanosomiasis, African
NCT00803933

Completed

Trial of DB289 for the Treatment of Stage I African Trypanosomiasis

Conditions: African Trypanosomiasis
NCT00802594

Completed

A Trial of DB289 for the Treatment of Stage I African Trypanosomiasis

Conditions: Trypanosomiasis, African
NCT00330148

Terminated

Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis

Conditions: Trypanosomiasis, African
NCT00489658

Terminated

Eflornithine + Nifurtimox Late-Stage Human African Trypanosomiasis (HAT)in West Nile, Uganda

Conditions: Trypanosomiasis, African
NCT00146627

Completed

Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African Trypanosomiasis

Conditions: Trypanosomiasis, African
NCT03087955

Active, not recruiting

Prospective Study on Efficacy and Safety of Acoziborole (SCYX-7158) in Patients Infected by Human African Trypanosomiasis Due to T.b. Gambiense

Conditions: Trypanosomiasis, African, Gambiense Trypanosomiasis, Sleeping Sickness
NCT03025789

Active, not recruiting

Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any Stage

Conditions: Trypanosomiasis, African, Sleeping Sickness, Trypanosomiasis; Gambian
NCT01533961

Completed

Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158

Conditions: Trypanosomiasis, Trypanosomiasis, African, Protozoan Infections, Parasitic Diseases
NCT03394976

Unknown status

Prospective Evaluation of an RDT to Screen for Gambiense HAT and Diagnose P. Falciparum Malaria

Conditions: Human African Trypanosomiasis
NCT00982904

Completed

Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the Fexinidazole

Conditions: Human African Trypanosomiasis
NCT00906880

Completed

Clinical Study to Assess the Tolerability, Feasibility and Effectiveness of Nifurtimox and Eflornithine (NECT) for the Treatment of Trypanosoma Brucei Gambiense Human African Trypanosomiasis (HAT) in the Meningo-encephalitic Phase

Conditions: Human African Trypanosomiasis
NCT02169557

Completed

Efficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open-label Cohort Study, plug-in to the Pivotal Study

Conditions: Human African Trypanosomiasis (HAT)
NCT02184689

Completed

Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal Study

Conditions: Human African Trypanosomiasis (HAT)
NCT02498782

Unknown status

Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas Disease

Conditions: Chagas Disease, Trypanosomiasis, South American, South American Trypanosomiasis, Disease, Chagas
NCT00123916

Completed

BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Disease

Conditions: Chagas Disease, Trypanosomiasis, Heart Disease
NCT03112655

Completed

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: Early Test-of-cure

Conditions: African Trypanosomiasis, African; Trypanosomiasis, West, Sleeping Sickness; West African, Trypanosoma Brucei Gambiense; Infection
NCT01685827

Completed

Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2

Conditions: Human African Trypanosomiasis (HAT), Sleeping Sickness
NCT04099628

Active, not recruiting

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP3 Post Elimination Monitoring

Conditions: Human African Trypanosomiasis, Sleeping Sickness, Trypanosoma Brucei Gambiense; Infection, West African Sleeping Sickness, African Trypanosomiases, Trypanosomiasis; African, Due to Trypanosoma Brucei Gambiense, Gambiense
NCT03356665

Completed

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case Detection

Conditions: African Trypanosomiases, West African; Trypanosomiasis, Sleeping Sickness; West African, Trypanosoma Brucei Gambiense; Infection
NCT01766830

Completed

Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)

Conditions: Visceral Leishmaniasis, Human African Trypanosomiasis, Enteric Fever, Melioidosis, Brucellosis, Leptospirosis, Relapsing Fever, Rickettsial Diseases, HIV, Tuberculosis, Malaria, Amoebic Liver Abscess