Clinical Trials on Vascular Anomaly With Thrombocytopenia

Total 845 results

Medical College of Wisconsin

Completed

Registry for Vascular Anomalies Associated With Coagulopathy (VAC)

Hemangiomas | Multifocal Lymphangioendotheliomatosis With Thrombocytopenia | Cutaneovisceral Angiomatosis With Thrombocytopenia | Vascular Anomaly With Thrombocytopenia

United States
Amgen

Completed

Safety and Efficacy Study of Romiplostim to Treat Immune Thrombocytopenia (ITP) in Pediatric Patients

Thrombocytopenia | Immune Thrombocytopenia | Idiopathic Thrombocytopenic Purpura | Thrombocytopenia in Pediatric Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | Thrombocytopenic Purpura

United States, Canada, Australia
Amgen

Completed

Safety and Efficacy Study of Romiplostim (AMG 531) to Treat ITP in Pediatric Subjects

Idiopathic Thrombocytopenic Purpura | Thrombocytopenia in Pediatric Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Kyowa Kirin Co., Ltd.

Completed

Safety Study of AMG 531 in Japanese Subjects With ITP

Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Amgen

Completed

Romiplostim (AMG 531) Versus Medical Standard of Care for Immune (Idiopathic) Thrombocytopenic Purpura

Thrombocytopenia | Idiopathic Thrombocytopenic Purpura | Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | Thrombocytopenic Purpura
Amgen

Completed

Retrospective & Prospective Observational Study of Patients With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

Thrombocytopenia | Idiopathic Thrombocytopenic Purpura | Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | Thrombocytopenic Purpura
Amgen

Completed

A Study Evaluating the Safety and Efficacy of Long-term Dosing of Romiplostim in Thrombocytopenic Pediatric Patients With Immune (Idiopathic) Thrombocytopenia Purpura

Thrombocytopenia in Pediatric Subjects With Immune Idiopathic Thrombocytopenic Purpura ITP

United States, Canada, Australia, Spain
Hutchmed

Recruiting

The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP)

Pathologic Processes | Immune System Diseases | Autoimmune Diseases | Hematologic Diseases | Hemorrhage | Hemorrhagic Disorders | Thrombotic Microangiopathies | Purpura | Purpura, Thrombocytopenic | Skin Manifestations | Thrombocytopenia | Purpura, Thrombocytopenic, Idiopathic | Immune Thrombocytopenia | Blood Coagulation... and other conditions

United States, Spain, Germany, Australia, Norway
Etablissement Français du Sang
University Hospital, Grenoble

Completed

Evaluation of the Efficacy of Platelets Treated With Pathogen Reduction Process (EFFIPAP)

Aplasia With Expected Thrombocytopenia

France
Peking University People's Hospital

Recruiting

The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Blood Coagulation Disorders | Thrombocytopenia | Immune Thrombocytopenia | Physiological Effects of Drugs

China
Archemix Corp.

Terminated

Clinical Outcome Study of ARC1779 Injection in Patients With Thrombotic Microangiopathy

Thrombotic Thrombocytopenic Purpura | Thrombotic Microangiopathy

United States, Italy, Austria, Canada, United Kingdom
University Hospital, Toulouse

Completed

Risk Factors for Thrombosis in Immune Thrombocytopenia (RiFT-ITP)

Immune Thrombocytopenia

France
Samarkand State Medical Institute

Active, not recruiting

Radial Visualization of the Foramen Arcuale Atlantis

Patients With Kimmerle's Anomaly

Uzbekistan
Assistance Publique - Hôpitaux de Paris

Completed

Early Predictive Factors of Cardiac and Cerebral Involvement in TMA (MATRISK)

Thrombotic Microangiopathies | Thrombotic Thrombocytopenic Purpura

France
Children's Hospital Medical Center, Cincinnati

Unknown

Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies

Tufted Angioma | Microcystic Lymphatic Malformation | Kaposiform Hemangioendotheliomas | Capillary Venous Lymphatic Malformation | Venous Lymphatic Malformation | Mucocutaneous Lymphangiomatosis and Thrombocytopenia | Capillary Lymphatic Arterial Venous Malformations | PTEN Overgrowth Syndrome With... and other conditions

United States
Eisai Inc.

Completed

Treatment of Thrombocytopenia in Patients With Chronic Liver DiseaseUndergoing an Elective Procedure

Thrombocytopenia Associated With Liver Disease

United States, Italy, China, Taiwan, Spain, Belgium, Poland, Portugal, Canada, Korea, Republic of, Australia, Brazil, Chile, Austria, Germany, Hungary, France, Argentina, United Kingdom, Thailand
Eisai Inc.

Completed

Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing an Elective Procedure

Thrombocytopenia Associated With Liver Disease

United States, China, Spain, Argentina, Belgium, Israel, Mexico, Romania, Japan, Brazil, Russian Federation, Germany, Italy, Czechia, Canada, Australia, France
Tongji Hospital

Recruiting

A 6-month Follow-up Study of Patients With Severe Fever With Thrombocytopenia Syndrome

Severe Fever With Thrombocytopenia Syndrome

China
Qin Ning

Recruiting

Evaluate the Efficacy and Safety of Various Treatment Schemes for Severe Fever With Thrombocytopenia Syndrome(SFTS)

Severe Fever With Thrombocytopenia Syndrome

China
Eisai Co., Ltd.

Completed

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Once-daily Oral Avatrombopag in Japanese Subjects With Chronic Liver Diseases and Thrombocytopenia

Thrombocytopenia Associated With Chronic Liver Disease

Japan
Baxalta now part of Shire

Completed

Safety and Efficacy Study of a 10% Intravenous Immune Globulin Solution in Subjects With Primary Immunodeficiency Disorders

Primary Immunodeficiency Diseases (PID) | Immune Thrombocytopenic Purpura (ITP) | Kawasaki Syndrome

United States
Northwell Health
Children's Hospital of Philadelphia; National Institute of Diabetes and Digestive... and other collaborators

Terminated

International Registry and Biorepository for TMA(Thrombotic Microangiopathy)

Thrombotic Thrombocytopenic Purpura | Hemolytic Uremic Syndrome | Thrombotic Microangiopathy

United States
University Hospital, Toulouse

Completed

The RITAI Cohort: An Observational Study on Rituximab Off-label Use for Auto-immune Disorders (RITAI)

Cryoglobulinemia | Cold Agglutinin Disease | Pemphigus | Auto-immune Thrombocytopenic Purpura | Hemolytic Auto-immune Anaemia

France
Nemours Children's Clinic

Recruiting

Topical Rapamycin/Sirolimus for Complicated Vascular Anomalies and Other Susceptible Lesions (NOVA)

Vascular Anomaly

United States
West China Hospital

Completed

Efficacy and Safety of Sirolimus to Vascular Anomalies

Vascular Anomaly

China
Massachusetts General Hospital
Bristol-Myers Squibb

Terminated

Efficacy and Safety of Apixaban in the Treatment of Heparin Induced Thrombocytopenia (HIT)

Heparin-induced Thrombocytopenia | Heparin-induced Thrombocytopenia and Thrombosis

United States
Children's Hospital Los Angeles

Completed

Pilot Dose Finding and Pharmacokinetic Study of Fondaparinux in Children With Thrombosis

Thrombosis | Heparin-induced Thrombocytopenia

United States
Centre Hospitalier Universitaire de Saint Etienne
Sanofi; Hyphen BioMed; CIC-EC de Saint-Etienne; Groupe d'étude sur l'Hémostase... and other collaborators

Completed

Heparin-Induced Thrombocytopenia: Development and Validation of a Predictive Clinical (Score-TIH)

Heparin-induced Thrombocytopenia

France
Canyon Pharmaceuticals, Inc.

Terminated

A Comparative Sudy Comparing Argatroban® IV vs Desirudin SC for Suspected HIT With or Without Thrombosis Syndrome (HIT)

Suspected Heparin-Induced Thrombocytopenia

United States
Chugai Pharmaceutical

Not yet recruiting

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Antiphospholipid Syndrome (APS) | Immune Thrombocytopenia (ITP) | Dermatomyositis (DM) | Bullous Pemphigoid (BP) | Behçet's Syndrome (BS) | Immune-mediated Necrotizing Myopathy (IMNM)

United States, Japan
Liaoning Tumor Hospital & Institute

Completed

To Evaluate Thrombosis Risk in Chemotherapy Patients With Solid Tumors Who Receiving Thrombocytopenia Treatment

Chemotherapy-induced Thrombocytopenia

China
Minia University

Completed

Surgical Management of Optic Disc Pit Maculaopathy

Maculopathy | Optic Disc Structural Anomaly
Children's Hospital Medical Center, Cincinnati
Lymphangiomatosis and Gorham's Disease Alliance (LGDA); Klippel Trenaunay (KT)... and other collaborators

Recruiting

Identification of Biomarkers for Patients With Vascular Anomalies

Kaposiform Hemangioendothelioma | Kaposiform Lymphangiomatosis | Vascular Anomaly | Klippel Trenaunay Syndrome | Generalized Lymphatic Anomaly | Gorham-Stout Disease | Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi

United States
The Medicines Company

Completed

Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (AT BAT, First Inning)

Thrombosis | Heparin-Induced Thrombocytopenia

United States
The Medicines Company

Withdrawn

Bivalirudin PCI Registry in Heparin Induced Thrombocytopenia/Heparin Induced Thrombocytopenia and Thrombosis Syndrome (HIT/HITTS) Patients

Heparin-Induced Thrombocytopenia | Heparin-induced Thrombocytopenia and Thrombosis Syndrome

United States
Johann Wolfgang Goethe University Hospital

Unknown

Generation of Heparin-induced Thrombocytopenia (HIT)-Antibodies Without Prior Heparin Exposure

Thrombosis | Heparin-Induced Thrombocytopenia

Germany
Wuhan Asia Heart Hospital

Unknown

Thrombotic Biomarkers to Predict Thrombosis in Heparin-induced Thrombocytopenia

Thrombosis | Biomarkers | Heparin-Induced Thrombocytopenia
AHEPA University Hospital

Completed

Impact of Cardiac Surgery With a Minimal Invasive Extracorporeal Circuit οn Coagulation: Data From Point of Care Devices

Coagulation Disorder | Extracorporeal Circulation; Complications | Extracorporeal Circulation of Blood; Thrombocytopenia

Greece
Fairview University Medical Center

Unknown

Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Giant Cell Arteritis | Wegener's Granulomatosis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Purpura, Schoenlein-Henoch | Juvenile Rheumatoid Arthritis | Takayasu Arteritis | Pure Red Cell Aplasia | Graft Versus Host Disease | Anemia, Hemolytic, Autoimmune and other conditions

United States
Case Comprehensive Cancer Center

Completed

Differentiation Therapy With Decitabine in Treating Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes | Thrombocytopenia | Chronic Myelomonocytic Leukemia | de Novo Myelodysplastic Syndromes | Refractory Anemia | Refractory Anemia With Excess Blasts | Refractory Cytopenia With Multilineage Dysplasia | Refractory Anemia With Ringed Sideroblasts

United States
Taiwan Liposome Company

Completed

Phase 1 Open-label Study to Evaluate Efficacy and Tolerability of TLC399 in Patients With Macular Edema Due to RVO

Central Retinal Vein Occlusion With Macular Edema | Branch Retinal Vein Occlusion With Macular Edema

Taiwan
Boston Children's Hospital

Completed

Pilot of Abatacept-based Immunosuppression for Prevention of Acute GvHD During Unrelated Donor HCT

AML | ALL | Biphenotypic Leukemia | Refractory Anemia | Refractory Cytopenia With Multilineage Dysplasia | Refractory Anemia With Ringed Sideroblasts | Undifferentiated Leukemia | Ref. Cytopenia w Multilineage Dysplasia & Ringed Sideroblasts | Refractory Anemia With Excess Blasts-1 (5-10% Blasts) | Refractory... and other conditions

United States
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Study on the Relationship Between Neutrophil-mediated Thrombocytopenia and the Condition and the Course of Disease in Patients With HFRS

Hemorrhagic Fever With Renal Syndrome

China
Ain Shams University

Unknown

Cerebral Dysfunction in Chronic ITPwith High Risk of Serious Bleeding Excluding Intracranial Hemorrhage.

Chronic Thrombocytopenia

Egypt
Umeå University

Completed

Perioperative Fluid Management in Morbidly Obese Patients

Hypotension | Dehydration | Anomaly; Venous Return

Sweden
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Automated Surveillance, Alert, and Rapid Diagnosis of Thrombotic Microangiopathies: the ASARD-TMA Study (ASARD-TMA)

Thrombotic Microangiopathies
AKARI Therapeutics

Recruiting

Nomacopan (rVA576) in Transplant Associated Thrombotic Microangiopathy

Thrombotic Microangiopathies

United States, United Kingdom, Poland
The First Affiliated Hospital of Soochow University

Completed

A Safety and Efficacy Study of NAC in Patients With TA-TMA

Hematologic Diseases | Thrombotic Microangiopathies

China
Omeros Corporation

Completed

Safety and Efficacy Study of OMS721 in Patients With Thrombotic Microangiopathies

Thrombotic Microangiopathies

United States, Belgium, Bulgaria, Hong Kong, Italy, Lithuania, Malaysia, New Zealand, Poland, Singapore, Taiwan, Thailand
Michal Nowicki

Available

OMS721 Compassionate Use in Patients With Thrombotic Microangiopathy

Thrombotic Microangiopathy

Clinical Trials on Vascular Anomaly With Thrombocytopenia

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CROs in Bulgaria

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