Clinical Trials on Vulvar HSIL

Total 590 results

Erasmus Medical Center
Dutch Cancer Society

Not yet recruiting

Adjuvant Nonavalent HPV Vaccination in Women Treated for Vulvar HSIL (VulVaccin)

HPV | Vulvar HSIL

Netherlands
National Cancer Institute (NCI)

Terminated

Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions

Neoplasms, Squamous Cell | Squamous Lntraepithelial Lesions of Vulva | Vulvar HSIL

United States
Maternal and Child Health Hospital of Hubei Province

Completed

Methylene Blue Injection for Nonneoplastic Epithelial Disorders of Vulva (NNEDsMB)

Nonneoplastic Epithelial Disorders of Vulva
University Women's Hospital Tübingen

Completed

Electrochemotherapy for the Inoperable Vulva Carcinoma

Advanced Inoperable Vulva Carcinoma

Germany
Inovio Pharmaceuticals

Completed

Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)

Human Papillomavirus (HPV) | Vulvar Dysplasia | Vulvar Intraepithelial Neoplasia (VIN) | Vulvar High Grade Squamous Intraepithelial Lesion (HSIL) | VIN2 | VIN3 | Pre-cancerous Lesions of the Vulva

United States
Newish Technology (Beijing) Co., Ltd.

Recruiting

Clinical Study of HPV Therapeutic DNA Vaccine (NWRD08) in Patients With Cervical HPV16 and/or HPV18 Positive

HSIL of Cervix

China
The Netherlands Cancer Institute

Recruiting

Treatment of Locally Advanced VULvar CArcinoma in a Neoadjuvant Setting With Carboplatin and Paclitaxel Chemotherapy (VULCANize) (VULCANize)

Locally Advanced, Squamous Cell Carcinoma of the Vulva

Netherlands
The Netherlands Cancer Institute

Recruiting

Treatment of Metastatic Vulvar Carcinoma With Carboplatin and Paclitaxel Chemotherapy (CRAVAT)

Metastatic Squamous Cell Carcinoma of the Vulva

Netherlands
University of Manchester
British Society for the Study of Vulval Disease

Completed

Early Detection of Vulval CAncer Through Self-Examination (EDuCATE): Intervention Study

Vulvar Cancer | Lichen Planus | Vulvar Lichen Sclerosus | Self-Examination | Vulval Intraepithelial Neoplasia | Vulval Cancer | Vulval Intraepithelial Neoplasia With Lichen Sclerosus

United Kingdom
AGO Research GmbH

Not yet recruiting

Pembrolizumab in Combination With Lenvatinib in Patients With Recurrent, Persistent, Metastatic or Locally Advanced Vulvar Cancer Not Amenable to Curative Surgery or Radiotherapy (PIERCE)

Recurrent Vulvar Cancer | Persistent Vulvar Cancer | Metastatic Vulva Cancer | Locally Advanced Vulvar Cancer
Leiden University Medical Center
University Medical Center Groningen; Erasmus Medical Center

Not yet recruiting

Neo-adjuvant Pembrolizumab in Vulvar Squamous Cell Carcinoma: a Clinical Proof-of-concept Study (Apollo)

Squamous Cell Cancer | Vulva Cancer | Vulva Neoplasm
Tufts Medical Center

Not yet recruiting

SLN Mapping and ICG Dye for Vulvar Cancer

Vulva Cancer

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Frantz Viral Therapeutics, LLC

Active, not recruiting

Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3) (ART-VIN)

Vulvar Diseases | Vulvar Dysplasia | HPV-Related Vulvar Intraepithelial Neoplasia | Preinvasive Vulvar Disease | Vulva Intraepithelial Neoplasia

United States
Rigshospitalet, Denmark
Aarhus University Hospital

Recruiting

Optical Guided Sentinel Node Biopsy for Staging of Vulvar Cancer (SENTIVUC II)

Sentinel Lymph Node | Vulva Cancer

Denmark
Diana Zach
Sahlgrenska University Hospital, Sweden; University Hospital, Linkoeping; Skane...

Completed

Sentinel Node Extended in Squamous Cell Vulvar Cancer (SNEX)

Sentinel Lymph Node | Vulva Cancer

Sweden
Center for Vulvovaginal Disorders

Completed

Platelet Rich Plasma (PRP) for Vulvar Lichen Sclerosus

Lichen Sclerosus of Vulva

United States
Fundación Eduardo Anitua

Not yet recruiting

Plasma Rich in Growth Factors (PRGF) for the Treatment of Lichen Sclerosus Atrophicus of the Vulva (PRGF)

Lichen Sclerosus of Vulva
CCTU- Cancer Theme
Alpha Tau Medical LTD.

Recruiting

A Safety and Efficacy Study of Intra-tumoural Diffusing Alpha Radiation Emitters for the Treatment of Vulva Cancer (DaRT-V)

Vulvar Squamous Cell Carcinoma | Vulva Cancer, Recurrent | Vulva Cancer

United Kingdom
Xijing Hospital

Recruiting

Carbon Dioxide（CO2）Fractional Laser Plus Photodynamic Therapy in Female Patients With Vulvar Lichen Sclerosus

Vulva Lichen Sclerosus

China
Centre Hospitalier Universitaire de Nice

Terminated

Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their Precursors

Vulvar Intraepithelial Neoplasia | Vulvar Mucosa Lesions

France
The Netherlands Cancer Institute

Recruiting

Primary Chemoradiation VS. Neoadjuvant Chemotherapy Followed By Surgery As Treatment Strategy For LAVC (VULCANIZE-II)

Squamous Cell Carcinoma of the Vulva | Locally Advanced Vulvar Carcinoma

Netherlands
Dana-Farber Cancer Institute

Completed

Image-Guided Gynecologic Brachytherapy (AMIGO)

Cervical Cancer | Vaginal Cancer | Uterine Cancer | Carcinoma of the Vulva

United States
Yangzhou University

Completed

Inhibitory Effect of Propofol on Perineal Pruritus in Patients Undergoing Day Surgery

Pruritus Vulvae

China
Meir Medical Center

Withdrawn

Vulvar Contact Dermatitis Resulting From Urine Incontinence

Urinary Incontinence | Vulvar Pruritus | Vulvar Contact Dermatitis

Israel
Gynecologic Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Observation in Patients With Early-Stage Vulvar Cancer Undergoing Sentinel Lymph Node Dissection (GROINSS-V)

Stage III Vulvar Cancer | Vulvar Squamous Cell Carcinoma | Stage I Vulvar Cancer | Stage II Vulvar Cancer

United States, Canada
Stratpharma AG

Recruiting

VALOR: Vaginal Atrophy & Long-term Observation of Recovery (VALOR)

Atrophic Vaginitis | Vaginal Atrophy | Lichen Sclerosus of Vulva | Genitourinary Syndrome of Menopause | Lichen Planus of Vulva | Lichen Simplex of Vulva (Disorder)

United States
Hospital Italiano de Buenos Aires

Terminated

The Use of Laser in the Treatment of Atrophic Vulvovaginitis

Lasers | Atrophy of Vagina | Atrophy Vulva

Argentina
Assistance Publique - Hôpitaux de Paris
Sorbonne University

Not yet recruiting

Development and Evaluation of an Artificial Intelligence Tool for Colposcopy Assistance (IACOL)

Cervical Cancer | LSIL | HSIL | Cervical Ectropion
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Bioimpedance Spectroscopy in Detecting Lower-Extremity Lymphedema in Patients With Stage I, Stage II, Stage III, or Stage IV Vulvar Cancer Undergoing Surgery and Lymphadenectomy

Lymphedema | Perioperative/Postoperative Complications | Stage II Vulvar Cancer AJCC v7 | Stage IIIA Vulvar Cancer AJCC v7 | Stage IIIB Vulvar Cancer AJCC v7 | Stage IIIC Vulvar Cancer AJCC v7 | Stage IVA Vulvar Cancer AJCC v7 | Stage IA Vulvar Cancer AJCC v7 | Stage IB Vulvar Cancer AJCC v7 | Stage IVB...

United States
Colleen Stockdale

Terminated

To Evaluate if the Medication Gabapentin Lessens Vulvar Pain

Vulvar Pain Symptoms | Vulvodynia (Chronic Vulvar Pain)

United States
Instituto do Cancer do Estado de São Paulo
University of Sao Paulo General Hospital

Active, not recruiting

New Strategy for the Treatment of Vulvar Cancer

Vulvar Neoplasm

Brazil
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Nelfinavir, Cisplatin, and External Beam Radiation Therapy for the Treatment of Locally Advanced Vulvar Cancer That Cannot Be Removed by Surgery

Stage II Vulvar Cancer AJCC v8 | Stage IIIC Vulvar Cancer AJCC v8 | Stage IVA Vulvar Cancer AJCC v8 | Stage III Vulvar Cancer AJCC v8 | Stage IIIA Vulvar Cancer AJCC v8 | Stage IIIB Vulvar Cancer AJCC v8

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Locally Advanced Squamous Cell Cancer of the Vulva

Stage III Vulvar Cancer AJCC v7 | Stage IIIA Vulvar Cancer AJCC v7 | Stage IIIB Vulvar Cancer AJCC v7 | Stage IIIC Vulvar Cancer AJCC v7 | Vulvar Squamous Cell Carcinoma | Stage IVA Vulvar Cancer AJCC v7

United States
Far Eastern Memorial Hospital
Gynecologic Oncology Group

Recruiting

The Association of G9a Protein and Clinical Outcome of Patients With Vulvar Cancer

Vulvar Cancer, G9a Protein

Taiwan
University of Rochester

Completed

Vulvar Vestibulitis Clinical Trial: Desipramine-Lidocaine

Vulvar Disease

United States
University of British Columbia

Completed

Physiotherapy Intervention for Provoked Vulvar Vestibulodynia

Vulvodynia | Provoked Vulvar Vestibulodynia

Canada
Shanghai Bovax Biotechnology Co., Ltd.
Chongqing Bovax Biopharmaceutical Co., Ltd.

Completed

Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

Vulvar Cancer | Vaginal Cancer | CIN1 | CIN2 | VaIN1 | VaIN2 | VaIN3 | Genital Wart | AIS | Invasive Carcinoma | Cervical Cancers | CIN 3 | Vin III | Mild Dysplasia of Vulva | Moderate Dysplasia of Vulva

China
University of Basel
University Hospital Inselspital, Berne; Foundation Cancer Research Switzerland

Unknown

A New Patient Reported Outcome Instrument to Assess Symptom Experience in Women With Vulvar Neoplasms (WOMAN-PRO) (WOMAN-PRO)

Women With Vulvar Intraephitelial Neoplasia or Vulvar Cancer

Switzerland, Germany
Alpha Tau Medical LTD.

Not yet recruiting

Alpha Radiation Emitters Device for the Treatment of Primary and Recurrent Squamous Cell Carcinoma of the Vulva (DaRT).

Carcinoma of the Vulva | Recurrent Carcinoma of the Vulva
St.Gallen University of Applied Sciences
Medical University of Vienna; University Hospital Inselspital, Berne; University... and other collaborators

Completed

The Impact of the "WOMAN-PRO II Program" on Patients With Vulvar Neoplasia to Minimize Post-surgical Symptom Prevalence (WOMAN-PROII)

Vulvar Cancer | Vulvar Intraepithelial Neoplasia

Switzerland
Hospital Universitari Vall d'Hebron Research Institute

Not yet recruiting

Intraoperative HPV Testing Evaluation

Recurrence | HSIL, High Grade Squamous Intraepithelial Lesions
McLean Center for Complementary and Alternative...

Unknown

Effect of Two Acupuncture Protocols on Vulvodynia (Acu/Vul-pain)

Vulvodynia | Vulvar Vestibulitis | Vulvodynia, Generalized | Vulvar Pain

United States
Western Galilee Hospital-Nahariya

Completed

Efficacy Study of Topical Application of Nifedipine Cream to Treat Vulvar Vestibulitis

Vulvar Diseases | Vulvodynia | Vestibulodynia | Vulvar Pain | Vestibulitis

Israel
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Recruiting

Electrochemotherapy With Carboplatinum Plus Bleomycin Versus Bleomycin Alone in Vulvar Cancer (Elechtra)

Vulvar Cancer

Italy
University of Medicine and Dentistry of New Jersey

Withdrawn

Chemoprevention of Cancer in the Lower Female Genital Tract: The Antineoplastic Activity of the Fungicide Ciclopirox.

Vulvar Cancer

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy or Surgery in Treating Patients With Previously Untreated Vulva Cancer With Positive Groin Lymph Nodes

Vulvar Cancer
Frantz Viral Therapeutics, LLC
The Cleveland Clinic

Recruiting

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) (ART-VIN IIB)

Vulvar Diseases | HPV Infection | Vulvar HSIL | High Grade Intraepithelial Neoplasia | HPV Disease | Pre-Cancerous Dysplasia | Vin II | Vin III | VIN, Usual Type | VIN 2 of Usual Type | VIN 3 of Usual Type | VIN Grade 2 | VIN Grade 3

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Unknown

Lymphedema After Surgery in Patients With Endometrial Cancer, Cervical Cancer, or Vulvar Cancer (LEG)

Lymphedema | Stage II Uterine Corpus Cancer | Stage IVB Vulvar Cancer | Stage IA Uterine Corpus Cancer | Stage IB Uterine Corpus Cancer | Stage IA Cervical Cancer | Stage IB Cervical Cancer | Stage II Vulvar Cancer | Stage IIA Cervical Cancer | Stage IA Vulvar Cancer | Stage IB Vulvar Cancer | Stage IIIA Vulvar... and other conditions

United States
Azienda Ospedaliera per l'Emergenza Canizzaro

Recruiting

Indocyanine Green Fluorescence Imaging, Sentinel Lymph Node Mapping in Patients With Vulvar Cancer

Vulvar Cancer

Italy
Peking Union Medical College Hospital

Completed

Clinical Implementation of Surface-guided Radiation Therapy in Vulvar Cancer

Vulvar Cancer

China

Clinical Trials on Vulvar HSIL

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