Clinical Trials on or Chronic Macular Hole (Symptom Duration > 6 Months)

Total 600 results

Samsung Medical Center

Unknown

The Intravitreal Autologous Platelet Concentrate Injection as an Adjunct of Vitrectomy for the Treatment of Refractory Macular Holes

Macular Hole With High Myopia (Spherical Equivalent ≤ -6.0 Diopters) or, | Large Size Macular Hole (Diameter > 600 Microns) or | Recurred or Failed Macular Hole From Previous Surgery | or Chronic Macular Hole (Symptom Duration > 6 Months)

Korea, Republic of
University Hospital Inselspital, Berne
UMC Utrecht; Cliniques universitaires Saint-Luc- Université Catholique de Louvain and other collaborators

Completed

OPtimising thERapy to Prevent Avoidable Hospital Admissions in the Multimorbid Older People (OPERAM)

3 or More Chronic Conditions for 6 Months or Longer | 5 or More Regular Drugs

Belgium, Ireland, Netherlands, Switzerland
University Hospital Inselspital, Berne
UMC Utrecht; Cliniques universitaires Saint-Luc- Université Catholique de Louvain and other collaborators

Completed

Health Economic Evaluation Alongside the OPERAM Trial

3 or More Chronic Conditions for 6 Months or Longer | 5 or More Regular Drugs

Belgium, Ireland, Netherlands, Switzerland
Vanderbilt University

Completed

Prospective Retinal and Optic Nerve Vitrectomy Evaluation (PROVE) Study (PROVE)

Glaucoma | Vitreomacular Traction | Macular Pucker | Macula Hole | Vitreous Opacities or Hemorrhage

United States
KTO Karatay University
Selcuk University; Nigde Omer Halisdemir University

Not yet recruiting

Effect of Kinesio Tape on Back Pain, Breastfeeding Success and Breastfeeding Self-Efficacy

Mothers Who Have Babies Between 0-6 Months and Are Actively Breastfeeding | Mothers Who Complain of Back Pain Due to Breastfeeding (Getting 6 Points or More on VAS in the Mothers' Own Evaluation)
Bin Li

Unknown

Efficacy Study of Gene Therapy for The Treatment of Acute LHON Onset Within Three Months (LHON)

Acute LHON | Onset Within Three Months | Onset Between 3 to 6 Months | Onset Between 6 to 12 Months | Onset Between 12 to 24 Months | Onset Between 24 to 60 Months | Onset Over 60 Months

China
MedImmune LLC

Completed

Study of Motavizumab (MEDI-524) and Palivizumab Administered Sequentially in the Same Respiratory Syncytial Virus (RSV) Season

Respiratory Syncytial Virus Infections | Chronic Lung Disease and <= 24 Months of Age or | Premature With Gestational Age <=35 Weeks and <=6 Months of Age

Australia, Chile, New Zealand
Memorial Sloan Kettering Cancer Center

Recruiting

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk

BRCA1 Mutation | BRCA2 Mutation | APC Gene Mutation | MLH1 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | PTEN Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | BARD1 Gene Mutation | MSH2 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | POLD1 Gene... and other conditions

United States
University of British Columbia

Completed

The Quality of Life and Direct Financial Costs Associated With Home Ventilation of Children: A Prospective Study

Children Receiving Ventilation at Home for Chronic Illness or Disease

Canada
Visionary Intelligence Ltd.
Peking University First Hospital; Beijing Municipal Science & Technology Commission

Completed

Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph

Diabetic Retinopathy | Retinal Vein Occlusion | Retinitis Pigmentosa | Optic Atrophy | Retinal Detachment | Epiretinal Membrane | Macular Holes | Central Serous Chorioretinopathy | Retinal Artery Occlusion | Suspect Glaucoma | Pathologic Myopia | Nonexudative Age-related Macular Degeneration | Exudative Age Related...

China
The Cleveland Clinic
National Eye Institute (NEI)

Recruiting

DISCOVER Study: Microscope-integrated Intraoperative OCT Study (DISCOVER)

Retinal Diseases | Retinal Detachment | Epiretinal Membrane | Fuchs Endothelial Dystrophy | Macular Hole

United States
Wuhan Union Hospital, China

Recruiting

Evaluating Efficacy and Safety of Flumatinib for Chronic Phase Chronic Myeloid Leukemia(CML-CP) Without Optimal Response (Warning,Failure) to Imatinib or Dasatinib

CML-CP; Mutation;Suboptimal Response or Failure in TKI

China
Hanmi Pharmaceutical Company Limited

Completed

An Observational Study to Evaluate the Incidence of MACCE According to Time Interval of Taking Medication in Patients With Acute Coronary Syndrome or Cerebral Infarction Who Received DAPT for the Secondary Prevention and Esomezol Cap for the Prevention of Gastrointestinal Bleeding

Acute Coronary Syndrome or B Cerebral Infarction Requiring DAPT(Clopidogrel + Aspirin) for at Least 6 Months

Korea, Republic of
University Hospital, Caen

Completed

Training Procedural Simulation of Nurses in Reducing Complications Related to Arteriovenous Fistula Puncture (SIMFAV)

Simulation | Arteriovenous Fistula | Nurse's Role

France
Inozyme Pharma
GACI Global

Not yet recruiting

PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

ATP-Binding Cassette Subfamily C Member 6 Deficiency | Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency
Oslo University Hospital
Stiftelsen Helse og Rehabilitering

Completed

Coping With Chronic Fatigue Syndrome: Development of a Community-based Patient Education Program

Chronic Fatigue Syndrome | Patient Education | Coping

Norway
Associazione Italiana per lo Studio del Pancreas

Recruiting

Registry of Subjects at Risk of Pancreatic Cancer (IRFARPC)

Lynch Syndrome | BRCA1 Mutation | BRCA2 Mutation | Familial Pancreatic Cancer | Hereditary Pancreatitis | Peutz-Jeghers Syndrome | FAMMM - Familial Atypical Mole Malignant Melanoma Syndrome

Italy
Baker Heart and Diabetes Institute
Queen's University, Belfast; University of Melbourne; Heartwest; Western Health

Recruiting

Risk-guided Disease Management in Coronary Artery Disease (Risk-CAD)

Coronary Artery Disease | Chronic Disease | Nurse's Role

Australia
University Hospital, Caen
NxStage Medical

Recruiting

Home Hemodialysis Assisted by a Nurse for Arterio-venous Fistula Cannulation (DIADIDEAL)

Hemolysis | Arteriovenous Fistula | Nurse's Role | Cannulation

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Embolization of the Middle Meningeal Artery for the Prevention of Chronic Subdural Hematoma Recurrence in High Risk Patients (EMPROTECT) (EMPROTECT)

Chronic Subdural Hematoma | at Risk of Post-operative Recurrence | Burr-hole Surgery

France
Mayo Clinic
Astellas Pharma Inc; Casimir, LLC

Recruiting

Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine

Mitochondrial Diseases | Mitochondrial Myopathies | Kearns-Sayre Syndrome | Mitochondrial DNA Mutation | Chronic Progressive External Ophthalmoplegia With Myopathy

United States
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

No longer available

HBCMD01- Expanded Access for the Treatment of Congenital Muscular Dystrophy.

Congenital Muscular Dystrophy Due to Lamin A/C Mutation

United States
Region Skane

Recruiting

BioMEL- Diagnostic and Prognostic Factors in Melanoma. (BioMEL)

Melanoma | Mutation | Image | Dysplastic Nevi | Melanoma in Situ | Mole (Dermatology)

Sweden
PTC Therapeutics

Completed

A Study to Evaluate the Safety and Pharmacokinetics of Ataluren in Participants From ≥6 Months to <2 Years of Age With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)

Nonsene Mutation Duchenne Muscular Dystrophy

United States
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

Lynch Syndrome | Pancreatic Ductal Adenocarcinoma | Chronic Pancreatitis | Pancreatic Cyst | Ataxia Telangiectasia | FAP | Peutz-Jeghers Syndrome | PALB2 Gene Mutation | BRCA Mutation | Fatty Pancreas | Genetic Pancreatic Cancer | Genetic Pancreatitis | Familial Atypical Multiple Mole-Melanoma

United States
Ministry of Health and Population, Egypt

Unknown

Vitrectomy With Planned Foveal Detachment for Refractory DME With or Without Vitreo-macular Interface Abnormality

Chronic Edema of the Macula
San Raffaele University
Unita' di Gastroenterologia - Policlinico Universitario di Bari; Unita' di... and other collaborators

Recruiting

Videocapsule Endoscopy in Lynch Syndrome

Lynch Syndrome | MLH1 Gene Mutation | MSH2 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | Lynch Syndrome II | Small Bowel Adenocarcinoma | Lynch Syndrome I

Italy
Sykehuset i Vestfold HF

Recruiting

Virtual Reality - A New Vision on Pain (VROP)

Back Pain | Musculoskeletal Pain | Chronic Pain | Musculoskeletal Diseases or Conditions | Pain, Chronic | Musculoskeletal Disorder | Musculoskeletal Neck Pain

Norway
University Hospital, Strasbourg, France

Terminated

Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension

Hypertension | Chronic Periodontitis

France
University of Arkansas

Withdrawn

Pancreatic Cancer Screening of High-Risk Individuals in Arkansas

Pancreatic Neoplasms | Colorectal Neoplasms, Hereditary Nonpolyposis | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Hereditary Pancreatitis | Ataxia Telangiectasia | Peutz-Jegher's Syndrome | Familial Atypical Mole-Malignant Melanoma Syndrome

United States
Asklepios Biopharmaceutical, Inc.

Recruiting

A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)

Muscular Dystrophy | Limb Girdle Muscular Dystrophy | LGMD2I | LGMD | Limb-Girdle Muscular Dystrophy Type 2 | LGMD2 | FKRP | FKRP Mutation | Fukutin Related Protein

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Cycling in Preventing Colorectal Cancer in Participants With Lynch Syndrome

High-Frequency Microsatellite Instability | Mismatch Repair Gene Mutation | Mutation-Negative Lynch Syndrome | Mutation-Positive Lynch Syndrome

United States
Radboud University Medical Center

Unknown

Muscle Relaxation in Myopathies With Positive Muscle Phenomena

Myotonic Dystrophy Type 2 | McArdle Disease | Nemaline Myopathy Type 6
Centre Hospitalier Régional Metz-Thionville

Completed

Identifying Risk Factors (RF) for Early Haemodialysis Arteriovenous Fistula Failure (eAVFF) (eAVFF-RF)

Hemodialysis | Arteriovenous Fistula | End Stage Chronic Renal Failure

France
National Institute of Allergy and Infectious Diseases...

Terminated

Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease

IFN-Gamma Therapy | CGD Gene Mutation | CGD Response to IFNg | CGD - Chronic Granulomatous Disease | Immunodeficiency Disease

United States
Yonsei University

Completed

Korean Multicenter Registry of ELUVIA Stent for Femoropopliteal Artery Disease (K-ELUVIA)

Symptomatic Peripheral Artery Disease With Femoropopliteal Lesions | Moderate or Severe Claudication (Rutherford Category 2 or 3) | Critical Limb Ischemia (Rutherford Category 4 or 5)

Korea, Republic of
Shanghai Changzheng Hospital
First Affiliated Hospital of Zhejiang University; The First Affiliated Hospital... and other collaborators

Unknown

Timing for Arteriovenous Fistula Creation and Its Effect on Target Organs in Patients With Chronic Renal Failure (TACTIC)

Renal Failure, Chronic
VenoStent

Active, not recruiting

SelfWrap-Assisted Arteriovenous Fistulas (SW-AVF)

Vascular Diseases | Urologic Diseases | Chronic Kidney Diseases | Renal Insufficiency | Renal Failure | End Stage Renal Disease | Hemodialysis Access Failure | Fistula | Arteriovenous Malformations | Vascular Malformations | End Stage Kidney Disease | Arteriovenous Fistula | Renal Failure Chronic | Vascular Fistula | Catheter Complications and other conditions

Paraguay
Hospital de Clinicas de Porto Alegre

Unknown

Effects of Aerobic Exercise on Arteriovenous Fistula

Chronic Kidney Diseases

Brazil
First Affiliated Hospital, Sun Yat-Sen University

Recruiting

Safety and Efficacy of Aspirin in Stroke Patients With Glucose-6-phosphate Dehydrogenase Deficiency (SAST) (SAST)

Stroke | G6PD Deficiency

China
Massachusetts General Hospital

Recruiting

Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)

Lynch Syndrome | Genetic Predisposition to Disease | Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation | Prostatic Neoplasm | ATM Gene Mutation | MMR Mutation

United States
Columbia University
National Institute on Aging (NIA)

Completed

Comparison of AVF Versus AVG in Elderly Patients Starting Dialysis

Chronic Kidney Disease | Endstage Renal Disease

United States
Assiut University

Unknown

Outcome of Arterio-venous Fistula for Adult Hemodialysis Patients in Assiut Governorate

Chronic Renal Failure

Egypt
Institute of Liver and Biliary Sciences, India

Completed

Outcomes of Renal Access Arteriovenous Fistulas for Hemodialysis in Patients With Chronic Renal Failure

End Stage Renal Disease

India
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

Fatigue | Overweight | Lynch Syndrome | Chronic Lymphocytic Leukemia | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Breast Carcinoma | Cancer Survivor | Ovarian Carcinoma | Health Status Unknown | Body Mass Index 25 or Greater

United States
Gilead Sciences
Ohio State University

Terminated

Phase I Study of Milatuzumab for Graft Versus Host Disease

Myelodysplastic Syndrome | Chronic Myelogenous Leukemia (CML) | Multiple Myeloma (MM) | GVHD (Acute or Chronic) | Acute Myeloid or Lymphoblastic Leukemia (AML or ALL) | Non-Hodgekin Lymphoma (NHL-both Follicular & Diffuse Large Cell) | Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia...

United States
Recursion Pharmaceuticals Inc.

Recruiting

A Study of REC-4881 in Participants With Cancers Which Have an AXIN1 or APC Mutation

Solid Tumor | APC Gene Mutation | AXIN1 Gene Mutation

United States
ASIS Corporation

Unknown

ASIS for Botox in Chronic Migraine (ASISinCM)

Chronic Migraine More than15 Days Per Month, and Lasting 4 Hours a Day or Longer.

United States
University of Alabama at Birmingham

Completed

Phosphodiesterase Type 5 Inhibition to Improve Endothelial Function and Vascular Remodeling in Chronic Kidney Disease and End Stage Renal Disease Patients Requiring New Arteriovenous Fistula

Improve Endothelial Function and Decrease Vascular Stenosis

United States
University Hospital, Grenoble

Not yet recruiting

Medical Benefit Evaluation of Ambulatory Activity Combining Rehabilitation and Therapeutic Education, Using an Intelligent Electric Bike for the Health, for the Effort Rehabilitation and the Quality of Life Improvement for Patients Suffering of Moderate Fibromyalgia (FIBROVELIS) (Fibrovelis)

Chronic Pain | Fibromyalgia | Adapted Physical Activity | Therapeutic Education | Electric Bike

Clinical Trials on or Chronic Macular Hole (Symptom Duration > 6 Months)

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