Search clinical trials for: [11C]MK-3168

Total 3901 results

Yale University

Terminated

FAAH Availability in Psychiatric Disorders: A PET Study

Post Traumatic Stress Disorder | Psychosis | Alcohol Use Disorder

United States
Celgene

Completed

Positron Emission Tomography (PET) Imaging Study to Evaluate Enzyme Availability in the Central Nervous System Before and After CC-97489 Administration in Healthy Participants

Healthy Volunteers

Belgium
Janssen Research & Development, LLC

Completed

A Study to Investigate the Regional Brain Kinetics of the Positron Emission Tomography Ligand 11C-MK-3168 and the Blocking of the Retention of the Ligand in the Human Brain by JNJ-42165279

Healthy

Belgium
Hoffmann-La Roche

Completed

Mass Balance and Absolute Bioavailability Study of RO7049389 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Merck Sharp & Dohme LLC

Completed

[11C]MK-6884 Positron Emission Tomography (PET) Tracer Validation Trial (MK-6884-001)

Alzheimer's Disease
Johnson & Johnson Vision Care, Inc.

Completed

Evaluating Soft Contact Lens Prototypes for Myopia Control

Visual Acuity

China
Guangzhou Lupeng Pharmaceutical Company LTD.

Completed

The Mass Balance Study of LP-168 in Healthy Subjects

Clinical Pharmacology

China
Merck Sharp & Dohme LLC

Completed

Positron Emission Tomography (PET) Study of Brain Calcitonin Gene-Related Peptide (CGRP) Receptor Occupancy After Telcagepant Administration (MK-0974-067)

Migraine
Wendell Yap, MD
University of Kansas Medical Center

No longer available

Clinical Management Decisions for Recurrent Prostate Cancer Patients Based on [11C]Acetate PET Scan

Prostate Cancer

United States
Jose Gutierrez, MD, MPH

Enrolling by invitation

Accelerated Non-Atherosclerotic Brain Arterial Aging Relationship to Alzheimer's Disease

Dementia | Alzheimer Disease

United States
José A. Luchsinger
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Albert... and other collaborators

Terminated

Brain Imaging in the Diabetes Prevention Program Outcomes Study (DPPOS-Brain)

Alzheimer Disease

United States
University of Southern California
National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute; Alzheimer's Clinical Trials Consortium

Recruiting

Trial-Ready Cohort-Down Syndrome (TRC-DS) (TRC-DS)

Dementia | Alzheimer Disease | Down Syndrome

United States, Spain, United Kingdom
National Institute of Mental Health (NIMH)

Completed

Positron Emission Tomography Imaging of Dopamine Receptors Using the Tracer [11C]NNC-112

Healthy

United States
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Phase 1 Trial to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-3167 Single Injection in Healthy Subjects and Patients With Type 2 Diabetes

T2DM

China
Heidelberg University
Merck Sharp & Dohme LLC

Recruiting

Effects of Riociguat on RIght VEntricular Size and Function in PAH and CTEPH (RIVERII)

Chronic Thromboembolic Pulmonary Hypertension | Primary Pulmonary Arterial Hypertension

Germany
MetiMedi Pharmaceuticals

Unknown

OMT-111 for Terminal Stage Solid Tumors

Breast Cancer | Pancreatic Cancer | Lung Cancer

Vietnam
Emory University

Completed

Norepinephrine Transporter Availability in PTSD

Posttraumatic Stress Disorder

United States
University of North Carolina, Chapel Hill
Boston Children's Hospital; Medical College of Wisconsin; National Football League

Enrolling by invitation

NFL LONG Prospective Study

Concussion, Brain

United States
AlgoRx Pharmaceuticals

Completed

Efficacy and Safety of ALGRX 3268 in Children Undergoing Minor Needle-Stick Procedures.

Pain

United States
AlgoRx Pharmaceuticals

Completed

Study of ALGRX 3268 for Needlestick Pain in Children

Pain

United States
Weill Medical College of Cornell University

Completed

Carbon-11 Butanol: Whole Body Radiochemical and Radiation Safety ([11C]Butanol)

Neuro-Degenerative Disease

United States
Columbia University

Recruiting

Exploratory Evaluation of [11C]MPC6827

Neurodegenerative Diseases | Amyotrophic Lateral Sclerosis | Alzheimer Disease

United States
National Institute of Mental Health (NIMH)

Terminated

PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel TSPO Radioligand

Dementia

United States
AlaMab Therapeutics (Shanghai) Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of ALMB-0168 in Patients With Osteosarcoma

Osteosarcoma
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First-in-Human Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tumors in China

Head and Neck Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Other Metastatic Solid Tumors

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First in Human, Dose Escalation Study of JAB-3068 （SHP2 Inhibitor） in Adult Patients With Advanced Solid Tumors

Head and Neck Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Other Metastatic Solid Tumors

United States
AlgoRx Pharmaceuticals

Completed

Efficacy and Safety of ALGRX 3268 in Management of Needlestick Pain in Children.

Procedural Pain

United States
Columbia University

Completed

Imaging Inflammation in Alzheimer's Disease With 11C-ER176

Alzheimer Disease

United States
Heidelberg University
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of Riociguat in Incipient Pulmonary Vascular Disease as an Indicator for Early PAH (ESRA)

Systemic Sclerosis | Pulmonary Vascular Disorder | Primary Pulmonary Hypertension | Other Systemic Involvement of Connective Tissue

Austria, Germany, Italy, France, Switzerland
Avid Radiopharmaceuticals
General Electric; American College of Radiology Imaging Network

Completed

Ability Of ([18F]-AV-45) PET Scan to Distinguish Alzheimer's Disease Subjects From Cognitively Normal Individuals

Alzheimer's Disease

United States
Hoffmann-La Roche

Completed

A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)

Solid Tumors

Hungary
Institute for Neurodegenerative Disorders

Terminated

Brain Imaging Study in Subjects With Alzheimer Disease in Comparison to Healthy Subjects

Alzheimer's Disease

United States
Hoffmann-La Roche

Completed

Evaluation of [11C]RO6924963, [11C]RO6931643, and [18F]RO6958948 as Tracers for Positron Emission Tomography (PET) Imaging of Tau in Healthy and Alzheimer's Disease (AD) Participants

Alzheimer's Disease, Healthy Volunteer

United States
Sunnybrook Health Sciences Centre
University Health Network, Toronto; GE Healthcare; Centre for Addiction and Mental... and other collaborators

Recruiting

BEAM: Brain-Eye Amyloid Memory Study (BEAM)

Parkinson's Disease | Mild Cognitive Impairment | Lewy Body Disease | Alzheimer's Disease | Vascular Cognitive Impairment

Canada
St. Jude Children's Research Hospital

Available

Expanded Access [11C] Methionine PET Imaging

Head and Neck Neoplasms | Central Nervous System Tumor

United States
Salarius Pharmaceuticals, LLC

Not yet recruiting

Study of SP-3164 in Relapsed or Refractory Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin's, Adult
Yale University
National Center for Complementary and Integrative Health (NCCIH)

Recruiting

Novel in Vivo Synaptic Imaging in Experienced Meditators (app311_med)

Behavior, Health

United States
Universitaire Ziekenhuizen KU Leuven
CHDI Foundation, Inc.

Completed

Dosimetry of [11C]CHDI-180R and [11C]CHDI-626.

Huntington Disease

Belgium
Yale University
National Institute of Mental Health (NIMH); National Institutes of Health (NIH)

Recruiting

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy (ART)

Healthy | HIV Dementia | HIV Associated Neurocognitive Disorder | HIV Encephalitis

United States
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC; Highlight Therapeutics

Terminated

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Refractory Hepatocellular Carcinoma

United States
Columbia University
National Institute on Aging (NIA)

Recruiting

Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease

Alzheimer Disease

United States
National Institute on Alcohol Abuse and Alcoholism...

Recruiting

Brain Dopaminergic Signaling in Opioid Use Disorders

Normal Physiology | Opioid Use Disorders

United States
Vanderbilt University Medical Center

Recruiting

Quantitative Imaging of Brain Glymphatic Function in Humans

Parkinson Disease

United States
Walter Reed Army Institute of Research (WRAIR)
National Institute of Mental Health (NIMH); National Intrepid Center of Excellence

Recruiting

CNS Correlates of Extended Sleep Restriction

Sleep Restriction

United States
University of Alabama at Birmingham

Not yet recruiting

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)

Mitral Valve Regurgitation

United States
University of Pennsylvania

Terminated

11C-Acetate PET/CT Imaging As a Biomarker of Amyloid-Induced Neuroinflammation

Mild Cognitive Impairment

United States
University of Pennsylvania
University of Miami; Biogen; University of Kansas

Terminated

Multimodal Imaging Outcome Measures for ALS (Image ALS)

ALS

United States
Johns Hopkins University
National Institute on Aging (NIA)

Completed

PET Imaging Study Using [11C]PIB in Subjects With AD & Healthy Volunteers

Alzheimer's Disease

United States
Synektik S.A.
European Commission

Completed

A Phase I Study of a Novel Tracer for Positron Emission Tomography "PET" Myocardial Perfusion Imaging "MPI"

Coronary Artery Disease
Mayo Clinic
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Long-term Effects of COVID-19

COVID-19 | SAR-CoV-2

United States

Search clinical trials for: [11C]MK-3168

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