Search clinical trials for: [14C]-AQX-1125 Oral Solution

Total 1400 results

Aquinox Pharmaceuticals (Canada) Inc.
Quotient Clinical

Completed

Phase 1 Absorption Distribution Metabolism and Excretion of AQX-1125 (ADME)

Healthy Volunteer

United Kingdom
Aquinox Pharmaceuticals (Canada) Inc.

Completed

Efficacy and Safety of AQX-1125 in Unstable COPD (FLAGSHIP)

COPD

United States, New Zealand, Poland, Australia, Denmark, Finland, Hungary, Sweden
Aquinox Pharmaceuticals (Canada) Inc.
Innovaderm Research Inc.

Completed

Pilot Efficacy and Safety Study of AQX-1125 in Atopic Dermatitis (KINSHIP)

Atopic Dermatitis

Canada
AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Mass Balance Recovery, Pharmacokinetics, Metabolite Profile and Metabolite Identification of [14C]AZD4831

Cardiovascular Disease

United Kingdom
Pfizer

Completed

A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males

Fungal Infection

United Kingdom
AstraZeneca
Quotient Sciences

Completed

An ADME Study of [14C]AZD0780 in Healthy Male Subjects

Cardiovascular Diseases

United Kingdom
Galapagos NV

Completed

Evaluation of Mass Balance and Absolute Bioavailability of GLPG3970

Healthy

United Kingdom
Aquinox Pharmaceuticals (Canada) Inc.

Unknown

Efficacy and Safety of 2 Doses of AQX-1125 in Subjects With Interstitial Cystitis / Bladder Pain Syndrome (LEADERSHIP 301)

Interstitial Cystitis | Painful Bladder Syndrome | Bladder Pain Syndrome | Chronic Interstitial Cystitis

United States, Belgium, Canada, Czechia, Denmark, Hungary, Latvia, Netherlands, Poland, Romania, Spain, United Kingdom
Millennium Pharmaceuticals, Inc.

Completed

Study to Assess Absolute Bioavailability (ABA) of TAK-906 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]-TAK-906 in Healthy Male Participants

Healthy Volunteers

United States
Aquinox Pharmaceuticals (Canada) Inc.

Terminated

Efficacy and Safety of AQX-1125 in Subjects With Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Chronic Prostatitis | Chronic Pelvic Pain Syndrome

Canada, United States
Boehringer Ingelheim

Completed

Investigation of the Metabolism and Pharmacokinetics of Ambroxol in Healthy Male Volunteers

Healthy
Galapagos NV

Completed

A Study in Healthy Male Volunteers to Test How the Test Medicine GLPG1972 is Taken up by the Body When Given by Mouth and Into the Vein as an Injection

Healthy

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]AZD9833

ER-positive, HER2-negative Breast Cancer

United Kingdom
Takeda

Completed

Study to Assess Absolute Bioavailability of TAK-935 (OV935) and to Characterize Mass Balance, Pharmacokinetics, Metabolism, and Excretion of [14C]TAK-935 (OV935) in Healthy Male Participants

Healthy Volunteers

United States
Bayer

Completed

A Study to Learn How BAY2927088 is Taken up and Handled by the Body in Healthy Male Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

Netherlands
Theravance Biopharma
GlaxoSmithKline; Hammersmith Medicines Research

Completed

A Phase 1 (Ph1), Single Dose (SD), GSK961081 Absorption, Distribution, Metabolism, and Excretion (ADME) Study in Healthy Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Pharmacokinetics (PKs) and Metabolism of Radiolabelled Linerixibat

Cholestasis

United Kingdom
Taiho Oncology, Inc.

Completed

Study of the Mass Balance of Oral FTD and TPI as Components of TAS-102 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Boehringer Ingelheim

Completed

Pharmacokinetics of Talsaclidine After Administration to Healthy Subjects

Healthy
Aquinox Pharmaceuticals (Canada) Inc.

Completed

Efficacy and Safety of AQX-1125 in IC/BPS (LEADERSHIP)

Interstitial Cystitis | Bladder Pain Syndrome

United States, Canada
Aquinox Pharmaceuticals (Canada) Inc.

Completed

Oral AQX-1125 and Combination Oral Contraceptive Drug-Drug Interaction Study (DDI-COC)

Healthy Volunteer

Netherlands
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-BI 409306 After Administration as Oral Solution in Healthy Male Volunteers

Healthy

United Kingdom
Taisho Pharmaceutical Co., Ltd.

Completed

Mass Balance Study of TS-142 in Healthy Adult Subjects.

Healthy Male Subjects

Japan
ViiV Healthcare

Completed

Pharmacokinetics and Metabolism of 14 Carbon [14C]-GSK3640254

HIV Infections

United Kingdom
GlaxoSmithKline

Completed

Absorption and Elimination of Radiolabeled Daprodustat

Anaemia

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Study Evaluating the Pharmacokinetic and Mass Balance of Single Dose [14C] AZD5718 in Volunteers

Cardiovascular Disease

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of [14C]AZD9977 in Healthy Male Subjects

Cardiovascular Disease

United Kingdom
Orion Corporation, Orion Pharma
Bayer

Completed

Mass Balance, Pharmacokinetics, Biotransformation and Bioavailability Study of ODM-201 in Healthy Male Subjects (ARIADME)

Healthy

United Kingdom
AstraZeneca
Quotient Sciences

Active, not recruiting

An ADME Study of [14C]AZD4604 and the Absolute Bioavailability of AZD4604

Asthma

United Kingdom
Pfizer

Active, not recruiting

A Study to Understand What the Body Does to the Study Medicine Called PF-07220060 When Taken by Healthy Adults

Healthy Participants

Netherlands
GlaxoSmithKline

Completed

Absorption & Elimination of Radiolabelled GSK2269557

Pulmonary Disease, Chronic Obstructive

United Kingdom
Bristol-Myers Squibb

Completed

A Study of Milvexian Using an IV Microtracer With Additional Formulation and Food Effect Comparison in Healthy Participants

Healthy Volunteers

United Kingdom
Pfizer

Completed

A Study in Healthy Adult Male Participants to Assess Absorption, Distribution, Metabolism and Excretion (ADME) of Radiolabeled PF-06865571.

Healthy Participants

United States
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men

Healthy Participants

Netherlands
Celtaxsys, Inc.
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-Acebilustat (CTX-4430)

Heathy Volunteers

United Kingdom
Corcept Therapeutics

Completed

Absolute Bioavailability and Metabolism Study of CORT118335 in Healthy Male Participants

Healthy

United Kingdom
Basilea Pharmaceutica

Completed

Mass Balance and Pharmacokinetics Study of Derazantinib in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Galapagos NV

Completed

Evaluation of Mass Balance and Absolute Bioavailability of GLPG3667

Healthy

United Kingdom
Debiopharm International SA

Completed

Mass Balance Recovery and Metabolic Profile of 14C Debio 1450 Following Single Oral and Intravenous Doses in Healthy Male Subjects

Healthy

United Kingdom
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-DK-AH 269 CL in 12 Healthy Male Volunteers

Healthy
Takeda

Completed

TAK-385 Phase I Absorption, Distribution, Metabolism, Excretion and Absolute Bioavailability Study

Healthy Volunteers

United Kingdom
Takeda

Completed

Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults

Healthy Volunteers

United States
Theravance Biopharma

Completed

TD-1473 Absorption, Distribution, Metabolism and Excretion (ADME) Study in Healthy Male Subjects

Bowel Diseases, Inflammatory | Intestinal Disorders

United States
Aldeyra Therapeutics, Inc.

Completed

A Randomized, Double Masked, Clinical Study of Subjects With Dry Eye Syndrome

Dry Eye Syndromes

United States
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of Savolitinib in Healthy Male Subjects

Cancer

United Kingdom
Neurocrine Biosciences
Takeda

Completed

A Study to Assess Absolute Bioavailability (ABA) of TAK-831 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]TAK-831 in Male Healthy Participants

Healthy Volunteers

United States
Galapagos NV

Completed

A Study in Healthy Male Volunteers to Look at How the Test Medicine GLPG1690 is Taken up by the Body When Given by Mouth and Into a Vein as an Injection

Healthy

United Kingdom
AlzProtect SAS

Active, not recruiting

A Study to Assess Tolerability, Safety, Pharmacokinetics and Effect of AZP2006 in Patients With PSP

Progressive Supranuclear Palsy

France
Crinetics Pharmaceuticals Inc.

Completed

Single and Multiple-Ascending Dose Study of CRN04894 in Healthy Volunteers

Healthy Volunteers

United States
Crinetics Pharmaceuticals Inc.

Completed

A Single and Multiple-Ascending Dose Study of CRN01941 in Healthy Adult Volunteers

Healthy Volunteers

Australia

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