Search clinical trials for: [14C]-LX4211

Total 2731 results

Hoffmann-La Roche

Completed

Mass Balance and Absolute Bioavailability Study of RO7049389 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Lexicon Pharmaceuticals

Completed

Efficacy, Safety, and PK of LX9211 in Patients With Diabetic Peripheral Neuropathic Pain (RELIEF-DPN 1)

Diabetes | Diabetic Peripheral Neuropathy

United States
Vivozon, Inc.

Completed

Absorption, Metabolism, Excretion, and Mass Balance Study of [14C]-VVZ-149 in Healthy Adult Male Subjects

Healthy Adult Male

United States
Rachel Lieberman

Terminated

Capsular Tension Rings in Intraocular Lens Rotation

Cataract | Ophthalmoplegia | Ophthalmologic Complication

United States
Lexicon Pharmaceuticals

Completed

Efficacy and Safety of LX9211 in Participants With Postherpetic Neuralgia (RELIEF-PHN1)

Postherpetic Neuralgia

United States, Czechia, Poland
Lux Biosciences, Inc.

Completed

A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis (LUMINATE)

Panuveitis | Uveitis, Posterior | Uveitis, Intermediate

United States, United Kingdom, Canada, Germany, Austria, France, India
Lux Biosciences, Inc.

Completed

Efficacy and Safety of Voclosporin to Treat Active Noninfectious Uveitis

Noninfectious Uveitis

France, United States, Italy, Germany, Canada, United Kingdom, Czech Republic, Austria, Brazil
Lexicon Pharmaceuticals

Recruiting

A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP) (PROGRESS)

Diabetic Peripheral Neuropathic Pain

United States
Lexicon Pharmaceuticals

Completed

Study to Determine the Safety, Tolerability and Pharmacokinetics Following Multiple Doses of LX4211 in Healthy Subjects

Healthy

United States
Taisho Pharmaceutical Co., Ltd.

Completed

Mass Balance Study of TS-142 in Healthy Adult Subjects.

Healthy Male Subjects

Japan
Lux Biosciences, Inc.

Completed

A Multi-center Study to Assess the Efficacy and Safety of LX211 in Active Non-infectious Anterior Uveitis (LUMINATE)

Uveitis, Anterior | Panuveitis

United Kingdom, Canada, United States, Germany, Austria, France, India
Lux Biosciences, Inc.

Completed

A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis (LUMINATE)

Panuveitis | Uveitis, Posterior | Uveitis, Intermediate

United States, United Kingdom, Canada, Germany, Austria, France, India
Hoffmann-La Roche

Completed

A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)

Solid Tumors

Hungary
CohBar, Inc.

Completed

A Phase 1a/1b Study of CB4211 in Healthy Non-obese Subjects and Subjects With Nonalcoholic Fatty Liver Disease

Nonalcoholic Fatty Liver Disease

United States
Lexicon Pharmaceuticals

Completed

Safety and Efficacy of LX4211 With Metformin in Type 2 Diabetes Patients With Inadequate Glycemic Control on Metformin

Type 2 Diabetes Mellitus

United States
Seagen Inc.
Gynecologic Oncology Group; European Network of Gynaecological Oncological... and other collaborators

Completed

A Trial of Tisotumab Vedotin in Cervical Cancer

Cervical Cancer

Belgium, Spain, United States, Denmark, Italy, Germany, Czechia, Sweden
Lexicon Pharmaceuticals

Completed

Study of Two Oral Formulations of LX4211 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Lexicon Pharmaceuticals

Completed

Study to Determine the Absorption, Metabolism, and Excretion of [14C]LX4211 in Healthy Male Subjects (AME)

Healthy

United States
Lexicon Pharmaceuticals

Completed

Study of LX4211 in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Lexicon Pharmaceuticals

Completed

Study to Define the Electrocardiogram Effects of a Single Dose of LX4211 in Healthy Subjects

Healthy

United States
Indivior Inc.

Completed

Single Dose Study of [14C]-IDV184001AN ([14C]-IDV184001) in Healthy Adult Male Participants

Opioid Use Disorder

United States
Arcus Biosciences, Inc.
Gilead Sciences

Completed

A Study Investigating the Safety, Absorption, and Elimination of Radioactively Labeled Etrumadenant, a New Compound in the Treatment of Cancer

Healthy Participants

Netherlands
Biogen
Denali Therapeutics Inc.

Completed

A Study of Mass Balance, Pharmacokinetics, Metabolite Profile, and Metabolite Identification of BIIB122/DNL151 in Healthy Male Subjects

Healthy Volunteers

United States
Laekna Limited

Completed

Human Mass Balance and Biotransformation Study of [14C]Afuresertib

Healthy Volunteer

China
Lexicon Pharmaceuticals

Completed

Study to Evaluate the Pharmacodynamic and Pharmacokinetic Effects of LX4211 in Subjects With Type 2 Diabetes and Renal Impairment

Type 2 Diabetes Mellitus | Renal Impairment

United States
Athira Pharma
Alturas Analytics, Inc.; Labcorp Drug Development Inc

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-Fosgonimeton (ATH-1017)

Healthy Volunteers

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Human AME Study for Omaveloxolone

Healthy Male Subjects

United States
Cyclerion Therapeutics

Completed

A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Olinciguat in Healthy Male Volunteers

Healthy Volunteers

United States
Denovo Biopharma LLC

Completed

A Study of LY2140023 in Healthy Participants

Healthy Participants

United Kingdom
Biogen
Denali Therapeutics Inc.

Completed

A Study to Determine the Absolute Bioavailability of BIIB122/DNL151 in Healthy Subjects

Healthy Volunteers

United States
AstraZeneca
Quotient Sciences

Completed

Study Evaluating the Pharmacokinetic and Mass Balance of Single Dose [14C] AZD5718 in Volunteers

Cardiovascular Disease

United Kingdom
Lexicon Pharmaceuticals

Completed

Study to Evaluate the Effect of Single Doses of LX4211 and Canagliflozin on Intestinal Glucose Absorption in Healthy Adult Subjects

Healthy Subjects

United States
Pfizer
Arvinas Estrogen Receptor, Inc.

Completed

A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults

Healthy

United States
H. Lundbeck A/S

Completed

Study Investigating the Safety and Tolerability of Lu AF88434 in Healthy Young Men

Healthy

Netherlands
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Mass Balance Study of TQB3616

Breast Cancer

China
Cascade Pharmaceuticals, Inc

Completed

Study of [14C]CS0159 in China Healthy Subjects

Primary Biliary Cholangitis

China
Haisco Pharmaceutical Group Co., Ltd.
The First Affiliated Hospital of Soochow University

Completed

Pharmacokinetics, Mass Balance, and Metabolism of [14C]HSK21542 in Healthy Adult Male Volunteers.

Peripheral Analgesic and Anti-itch

China
Sichuan Haisco Pharmaceutical Group Co., Ltd
First Affiliated Hospital of Suzhou Medical College

Completed

Mass Balance and Biotransformation of [14C]HSK7653 in Human

Type II Diabetes

China
Dizal Pharmaceuticals

Completed

Pharmacokinetic and Mass Balance Study of Oral-Administrated [14C]-DZD9008 in Healthy Male Subjects

Healthy Volunteers

United States
Xenon Pharmaceuticals Inc.

Completed

Single-dose Mass Balance Recovery and Metabolite Profile and Identification of 14C-XEN1101

Healthy Volunteers

United Kingdom
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

Mass Balance and Biotransformation Study of [14C]DBPR108 in Human

Healthy Male Subjects

China
Ascentage Pharma Group Inc.
HealthQuest Pharma Inc.

Completed

The Absorption, Metabolism and Excretion of [14C] HQP1351 in Humans

Chronic Myeloid Leukemia (CML)

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

The Mass Balance and Biotransformation of [14C]Donafenib in Healthy Adult Man

Healthy Male Adult

China
Spectrum Pharmaceuticals, Inc

Completed

Study of the Absorption, Metabolism, and Excretion Following a Single Dose of [14C]-Poziotinib in Healthy Male Subjects

Healthy

United States
LG Chem

Completed

Mass Balance Study of [14C]LC350189 in Healthy Volunteers

Hyperuricemia | Gout

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Study to Evaluate the Mass Balance and Biotransformation of [14C]SHR4640 in Chinese Healthy Adult Male Volunteers.

Healthy Adult Male Volunteers

China
Achaogen, Inc.
Celerion

Completed

A Study to Assess the Metabolism, Excretion, and Mass Balance of Radio-Labeled Plazomicin

Healthy Volunteers

United States
AstraZeneca

Completed

Open Label, Healthy Volunteers, ADME Study With Single Oral Administration of [14C] AZD5069

Healthy

United Kingdom
Eli Lilly and Company

Completed

A Study of LY2801653 in Healthy Participants

Healthy Volunteers

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate Absorption, Metabolism, and Excretion of 14C-JNJ26489112 in Healthy Male Participants

Healthy Participants

Belgium

3

Subscribe