Search clinical trials for: 10 mg CVL-231 as IR formulation

Total 82 results

Cerevel Therapeutics, LLC

Completed

Pharmacokinetics of CVL-231 Following Single Oral Administration of Modified- and Immediate-release Formulations in Fasted and Fed Healthy Participants

Schizophrenia

United States
Cerevel Therapeutics, LLC

Recruiting

A Trial of 10 and 30 mg Doses of CVL-231 (Emraclidine) in Participants With Schizophrenia

Schizophrenia

United States, Bulgaria
Cerevel Therapeutics, LLC

Recruiting

A Trial of 15 and 30 mg Doses of CVL-231 (Emraclidine) in Participants With Schizophrenia

Schizophrenia

United States, Bulgaria, Hungary
Cerevel Therapeutics, LLC

Recruiting

A Study to Evaluate Safety and Tolerability of CVL-231 (Emraclidine) in Adult Participants With Schizophrenia

Schizophrenia

United States, Bulgaria, Hungary, Puerto Rico
H. Lundbeck A/S

Completed

Bioequivalence Study of Lu AF35700

Healthy

United Kingdom
Cerevel Therapeutics, LLC

Recruiting

A Study Evaluating the Pharmacokinetics and Relative Bioavailability of Emraclidine Immediate-Release Tablets in Healthy Adult Participants

Healthy Participants

United States
Bayer
Merck Sharp & Dohme LLC; Duke Clinical Research Institute; Canadian VIGOUR Centre

Completed

Patient-reported Outcomes in Vericiguat-treated Patients With HFpEF (VITALITY-HFpEF)

Chronic Heart Failure With Preserved Ejection Fraction

Spain, United States, Belgium, Singapore, Taiwan, Canada, Japan, Italy, Austria, Bulgaria, Germany, Greece, Israel, Poland, Portugal, Hungary, Russian Federation, Argentina, Colombia, Malaysia, South Africa
Pfizer

Completed

PK Study in Adult Healthy Volunteers to Assess QD Dosing With the Selected Age-appropriate MR Formulations

Healthy

United States
Daewon Pharmaceutical Co., Ltd.

Completed

Phase 1 Study to Compare the Pharmacokinetic Characteristics and Food Effect of Pelubiprofen (30mg) Tablet IR TID and Pelubiprofen SR (as a Pelubiprofen 90 mg) Tablet QD in Healthy Subjects

Healthy
Bayer

Completed

Relative Bioavailability and Food Effect Study With Vericiguat to Characterize the Pediatric Formulation in Adult Healthy Subjects

Pharmacokinetics

Germany
Caliway Biopharmaceuticals Co., Ltd.

Completed

A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With Dercum's Disease Lipomas

Dercum's Disease

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Pharmacokinetic and Safety Trial to Determine the Appropriate Dose for Pediatric Patients With Multidrug Resistant Tuberculosis

Pediatric | Multidrug Resistant Tuberculosis

Philippines, South Africa
Novo Nordisk A/S

Completed

A Research Study Looking Into Blood Levels of Semaglutide and NNC0480-0389 When Given in the Same Injection or in Two Separate Injections in Healthy People

Diabetes Mellitus, Type 2

Germany
NeuroActiva, Inc.

Completed

A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831

Neurocognitive Disorders | Neurodegenerative Diseases | Cognitive Impairment | Alzheimer Disease | Tauopathies | Mild Cognitive Impairment | Dementia, Vascular | Dementia With Lewy Bodies | Alzheimer Dementia | Cognitive Disorder

New Zealand
Pfizer

Completed

A Healthy Volunteer Trial to Gain Information About the Blood Concentrations of PF-06412562 After Oral Administration of a Modified Release Formulation in Fasted and Fed Conditions

Healthy

Belgium
Eisai Inc.
Eisai Limited

Completed

Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients With Moderate to Severe Alzheimer's Disease

Alzheimer's Disease

United States
HeNan Sincere Biotech Co., Ltd

Recruiting

A Study of CL-197 Capsules in Healthy Participants

HIV-1

China
Ambrilia Biopharma, Inc.

Terminated

Safety and Biological Activity of C2L-OCT-01 PR in Acromegalic Patients

Acromegaly

United States, Belarus, Hungary, Serbia, Ukraine, Romania
Mundipharma Research Limited

Completed

Study to Assess Pharmacokinetic (PK), Bioavailability & Food Effect of MR902 Compared With Immediate Release (IR) Morphine Sulphate Oral Solution

Opioid Substitution Treatment
Novartis Pharmaceuticals

Completed

Dose-ranging Safety and Tolerability Study in Subjects ≥60 Years of Age

Alzheimer's Disease

Netherlands, United States, Belgium, Germany, United Kingdom
Asan Medical Center

Unknown

Clinical Trial to Characterize Pharmacokinetic-pharmacodynamic (PKPD) of Prasugrel 10 mg or 30 mg in Healthy Volunteers (PRAS-AM)

Healthy

Korea, Republic of
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

Evaluating the Safety and Immunogenicity of HIV-1 Vaccines Based on Chimpanzee Serotypes of Ad Expressing Clade C gp140 and a CH505TF gp120 Protein Boost in Healthy, HIV- Uninfected Adult Participants (HVTN139)

HIV Infections

South Africa
H. Lundbeck A/S

Completed

Study of the Safety, Tolerability, and Pharmacokinetics of Once Weekly Zicronapine in Patients With Schizophrenia

Schizophrenia

United States
GlaxoSmithKline

Completed

A Phase I/II Clinical Study of SK&F-105517-D in Japanese Patients With Chronic Heart Failure

Heart Failure, Congestive

Japan
Trevena Inc.

Completed

A Safety, Tolerability, PD and PK Study in Healthy Adults

Healthy

United States
MacroGenics
Merck Sharp & Dohme LLC

Completed

Combination Margetuximab and Pembrolizumab for Advanced, Metastatic HER2(+) Gastric or Gastroesophageal Junction Cancer

Stomach Cancer | Gastric Cancer | Esophageal Cancer

Korea, Republic of, United States, Taiwan, Singapore, Canada
Biolipox AB

Completed

Taste and Local Tolerance Study of NLA Nasal Spray in Patients With Allergic Rhinitis

Allergic Rhinitis

Sweden
Actavis Inc.

Completed

A Relative Bioavailability Study of Amlodipine Besylate 10 mg Tablets Under Fasting Conditions

Healthy

Canada
Central Institute of Mental Health, Mannheim
German Research Foundation

Completed

Hydrocortisone in the Treatment of Intrusions in Patients With Posttraumatic Stress Disorder

Posttraumatic Stress Disorder

Germany
Actavis Inc.

Completed

A Relative Bioavailability Study of Amlodipine Besylate 10 mg Tablets Tablets Under Fed Conditions

Healthy

Canada
Merck Sharp & Dohme LLC

Completed

Phase I Study of Dalotuzumab (MK-0646) in Combination With Cetuximab and Irinotecan in Participants With Colorectal Cancer (MK-0646-016)

Colorectal Cancer
Pacira Pharmaceuticals, Inc

Completed

Study to Characterize the Local Duration of Exposure From FX006 in Patients With Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
University of Zurich

Terminated

Low-dose Cortisol in Chronic Posttraumatic Stress Disorder

Posttraumatic Stress Disorder

Switzerland
Pacira Pharmaceuticals, Inc

Completed

Pharmacokinetic and Pharmacodynamic Study of FX006 in Patients With Osteoarthritis of the Knee

Osteoarthritis of the Knee

Australia
Ranbaxy Laboratories Limited
Ohm Laboratories, Inc.

Completed

Bioequivalence Study of Cetirizine Hydrochloride 10mg Tablets Under Fed Conditions

Healthy

United States
University of Pennsylvania

Recruiting

Ibudilast for Treating Alcohol Use Disorder (Ibudilast)

Alcoholism | Alcohol Use Disorder (AUD)

United States
Shire

Completed

Once-daily Oral Modified Release Hydrocortisone in Patients With Adrenal Insufficiency

Adrenal Insufficiency
MedImmune LLC
Thrombolysis in Myocardial Infarction (TIMI) Study Group

Completed

A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction (REAL-TIMI 63B)

ST Elevation Myocardial Infarction

Netherlands, United Kingdom, Brazil, Spain, Slovakia, Israel, Czechia, Hungary, Poland, Russian Federation
Danone Research

Completed

Effects of Fermented Milk Product Enriched With Plant Sterols and Policosanols in Mild Hypercholesterolaemic Adults

Mildly Hypercholesterolemic Subjects

United Kingdom
EMD Serono

Completed

Comparison of Anastrozole Verses Clomiphene Citrate in Stimulating Follicular Growth and Ovulation in Infertile Women With Ovulatory Dysfunction

Anovulation

United States
Bayer

Completed

Consumer Preference Study of Two Formulations of Phenylephrine Hydrochloride (Study CL2008-15)(P07530)(COMPLETED)

Seasonal Allergic Rhinitis | Vasomotor Rhinitis
Vallon Pharmaceuticals, Inc.

Completed

Study to Evaluate the Abuse Liability, Pharmacokinetics, Safety and Tolerability of an Abuse-Deterrent d-Amphetamine Sulfate Immediate Release Formulation (ADAIR) (SEAL)

ADHD | Narcolepsy

United States
Radboud University Medical Center
CoMentis

Completed

Anti-inflammatory Effects of GTS-21 After LPS

Sepsis | Endotoxemia | Vagal Activity

Netherlands
Jimmy Barbalho
University of Pernambuco

Completed

Comparative Study of Hemodynamic Changes Caused by Diazepam and Midazolam During Third Molar Surgery

Anxiety

Brazil
Emotional Brain NY Inc.

Completed

Lybridos in Pre-and Postmenopausal Women With Hypoactive Sexual Desire Disorder

Hypoactive Sexual Desire Disorder

United States
Gazi University

Completed

Comparing the Effects of Levobupivacaine and Bupivacaine in Saddle Spinal Anesthesia

Drug Effect | Anesthesia | General Surgery | Outpatients | Anorectal Disorder
Zuyderland Medisch Centrum
AtriCure, Inc.

Recruiting

Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum (ICE)

Funnel Chest | Pectus Excavatum

Netherlands
Hospital for Special Surgery, New York

Completed

Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery. (LMA vs Spinal)

Pain | Spinal Anesthesia | Postoperative Nausea and Vomiting | General Anesthesia | Nerve Block

United States
Afyon Kocatepe University Hospital

Completed

Choroidal Thickness and Its Correlations With Ocular Parameters in Primary Open-angle Glaucoma

Glaucoma, Open-Angle
Monash Medical Centre
Monash University

Recruiting

FASST - Fetal Alcohol Spectrum Stimulant Trial (FASST)

Fetal Alcohol Spectrum Disorders

Australia

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