Search clinical trials for: 120 mg sodium nitrite inhalation solution

Total 518 results

Aires Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and PK Parameters of Sodium Nitrite Inhalation Solution in Healthy Subjects

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States
Aires Pharmaceuticals, Inc.

Terminated

A Phase 2 Study to Determine the Safety and Efficacy of AIR001 in Subjects With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United States, Australia, Hungary
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI); Aires Pharmaceuticals, Inc.

Completed

Inhaled Sodium Nitrite on Heart Failure With Preserved Ejection Fraction

Heart Failure

United States
Aires Pharmaceuticals, Inc.

Terminated

Long-term Study of AIR001 in Subjects With WHO Group 1 Pulmonary Arterial Hypertension Who Completed AIR001-CS05

Pulmonary Arterial Hypertension

United States, Australia, Hungary
Aires Pharmaceuticals, Inc.

Completed

Dose-Finding, Safety, Pharmacodynamic Effect Study of Sodium Nitrite Inhalation Solution in Normal, Healthy Volunteers (AIR001-CS02)

Pulmonary Arterial Hypertension

United States
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest (SNOCAT)

Out-Of-Hospital Cardiac Arrest

United States
Hope Pharmaceuticals

Terminated

Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage

Subarachnoid Hemorrhage

United States
Rigel Pharmaceuticals

No longer available

Expanded Access of Fostamatinib in Patients With Persistent or Chronic Relapsing/Refractory ITP

Immune Thrombocytopenic Purpura
Pain Therapeutics
National Institute on Aging (NIA)

Completed

A Safety Study of PTI-125 in Healthy Volunteers

Alzheimer Disease | Alzheimer Disease, Early Onset

United States
Merck Sharp & Dohme LLC

Terminated

Evaluation of the Diagnostic Utility of INS316 in Patients With Interstitial Lung Diseases (01-701)

Interstitial Lung Disease
Merck Sharp & Dohme LLC

Completed

A Safety and Tolerability Study of Denufosol in 2-4 Year Olds (REACH-1)

Cystic Fibrosis
Santen Inc.

Completed

A Phase I/II Safety, Tolerability, Immunogenicity, and Bioactivity Study of DE-122 Injectable Solution for Refractory Exudative Age-related Macular Degeneration (PAVE)

Age-Related Macular Degeneration

United States
Schmidhofer, Mark, MD

Completed

Inhaled Nitrite in Subjects With Pulmonary Hypertension

Pulmonary Hypertension | Heart Failure, Diastolic

United States
Erling Bjerregaard Pedersen

Completed

The Effect of Sodium Nitrite on Renal Function and Blood Pressure in Healthy Humans. A Dose-response Study

Healthy

Denmark
Apeiron Biologics
Apeiron Respiratory Therapies GmbH

Completed

Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Inhaled APN01 Developed as Treatment for COVID-19

Covid19

Austria
Merck Sharp & Dohme LLC

Completed

Study of Denufosol Inhalation Solution in Patients With Mild Cystic Fibrosis Lung Disease

Cystic Fibrosis
Rigel Pharmaceuticals

Withdrawn

Open Label Study of Fostamatinib in the Treatment of IgA Nephropathy

IGA Nephropathy
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Solid Formulations of JNJ-39393406 in Healthy Male Participants

Healthy

Belgium
Barts & The London NHS Trust
Queen Mary University of London

Completed

Safety and Effectiveness of Intra-coronary Nitrite in Acute Myocardial Infarction (NITRITE-AMI)

Myocardial Infarction | Myocardial Ischemia | Cardiovascular Diseases | Reperfusion Injury

United Kingdom
Novartis Pharmaceuticals

Completed

Study of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inclisiran in Chinese Participants With Elevated Serum LDL-C (ORION-14)

Hyperlipidemia

China
Gladwin, Mark, MD

Terminated

Sodium Nitrite in Lung Transplant Patients to Minimize the Risk of Pulmonary Graft Dysfunction

Primary Graft Dysfunction

United States
Taivex Therapeutics Corporation

Recruiting

Safety and Tolerability Study for T-1201 Injection 100 mg Kit in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Taiwan
Barry Borlaug
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training) (INABLE)

Heart Failure

United States
Apeptico Forschung und Entwicklung GmbH

Recruiting

Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Oedema in Patients With Moderate-to-severe ARDS

ARDS

Austria, Germany
Hope Pharmaceuticals

Withdrawn

Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite

COVID-19 | Acute Respiratory Distress Syndrome | Acute Respiratory Failure

United States
University of Aberdeen
Imperial College London; Medical Research Council; Brighton and Sussex University... and other collaborators

Completed

Nitrites in Acute Myocardial Infarction (NIAMI)

Acute ST Elevation Myocardial Infarction

United Kingdom
Almirall, S.A.

Completed

Efficacy and Safety of Tildrakizumab 100 Milligrams (mg) in Participants With Moderate-Severe Chronic Plaque Psoriasis and Its Impact on Their Quality of Life (TRIBUTE) (TRIBUTE)

Plaque Psoriasis

Spain, Italy
Maastricht University Medical Center

Completed

Nitrate Supplementation; Duration (NO-how)

Nitrate | Time-trial Performance | Submaximal Exercise Performance | Nitrite

Netherlands
Debiopharm International SA

Completed

A Study to Evaluate the Absorption, Metabolism, and Excretion and Absolute Bioavailability of Xevinapant in Healthy Male Participants

Healthy Volunteers

United Kingdom
University of Mississippi Medical Center

Terminated

Vascular Dysfunction in Black Individuals: Roles of Nitric Oxide and Endothelin-1 (UMMC_Pilot)

Vascular Function | Racial Disparity

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Efficacy and Safety of DE-127 Ophthalmic Solution in Subjects With Mild or Moderate Myopia (APPLE)

Myopia

Singapore
Future Medicine
Futuremedicine Australia

Recruiting

FM101 Safety, Tolerability, Efficacy Study in the Patients With Ocular Hypertension

Ocular Hypertension

Australia
BioCryst Pharmaceuticals

Terminated

Study of Forodesine Hydrochloride in Patients With Relapsed/Refractory Precursor T-Lymphoblastic Leukemia/Lymphoma Who Have Failed Two or More Prior Treatment Regimens

Lymphoma | Leukemia

United States
MediBeacon

Completed

Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types

Acute Kidney Injury

United States
National Cancer Institute, Naples

Active, not recruiting

Comparison of Bowel Cleansing Regimens Prior to Colonoscopy (PRECOL2011-1)

Patients Undergoing Elective Colonoscopy

Italy
Novartis

Completed

Efficacy and Safety of 28 or 56 Day Treatment for Pseudomonas Aeruginosa in Children With Cystic Fibrosis (ELITE)

Cystic Fibrosis
dr. P. Noordzij
Pharmacosmos A/S

Recruiting

Intravenous Iron to Treat Postoperative Anemia in Older Cardiac Surgery Patients (AGE-ANEMIA)

Iron Deficiency Anemia

Netherlands
Heptares Therapeutics Limited

Completed

Comparison of Blood Levels of HTL0016878 From an Oral Capsule and an Oral Solution

Healthy Subjects

United Kingdom
University of Washington

Completed

A Phase II Trial of Lanreotide for the Prevention of Postoperative Pancreatic Fistula

Pancreatectomy; Hyperglycemia | Pancreatic Fistula | Pancreaticoduodenal; Fistula | Pancreatic Leak

United States
La Jolla Pharmaceutical Company

Completed

A Phase 2a Study of Weekly Doses of GCS-100 in Patients With Chronic Kidney Disease

Chronic Kidney Disease

United States
AstraZeneca

Completed

A Study to Assess the Bioavailability and to Compare the Pharmacokinetics of AZD7594 Inhaled Via Monodose Inhaler and Multiple-dose Dry Powder Inhalers (DPI) or Pressurized Metered-dose Inhaler (pMDI) in Healthy Male Subjects

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United States
Aquilon Pharmaceuticals S.A.

Completed

Crossover Trial to Assess Efficacy and Safety of Inhaled AQ001S Compared to a Budesonide Suspension in Mild Asthmatics (BOREAS)

Asthma

Belgium
Jazz Pharmaceuticals
Evidilya S.r.l.

Not yet recruiting

Epidyolex® in Lennox Gastaut and Dravet Syndrome: an Observational Study in ITALY (EpiTALY)

Dravet Syndrome | Lennox Gastaut Syndrome

Italy
Swiss Paraplegic Centre Nottwil
University of Zurich

Completed

Dose and Response of Dietary Nitrate in Healthy and Active Men

Healthy

Switzerland
Emergent BioSolutions
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Safety and Pharmacokinetics of UV-4B Solution Administered Orally as Multiple Ascending Doses to Healthy Subjects

Viral Infection

United States
Janssen R&D Ireland

Completed

A Study to Assess Bioavailability & Food Effect of Different Liquid and Capsule Formulations of TMC435.

Healthy Volunteers

United Kingdom
AstraZeneca
Quotient Sciences

Active, not recruiting

An ADME Study of [14C]AZD4604 and the Absolute Bioavailability of AZD4604

Asthma

United Kingdom
Boston Scientific Corporation

Completed

COMFORT: A Multicenter, Open-label, Randomized, Crossover Study (COMFORT)

Varicose Veins

United States
University of East Anglia

Unknown

The Haem and Nitrite Study - The Effects of Haemoglobin NO-blockade on Nitrite-induced Forearm Vessel Dilatation

Healthy Volunteers

United Kingdom
Sarah Sabry Hashem

Completed

Warfarin Initiation in Mechanical Mitral Valve Replacement Patients

Mitral Valve Disease

Egypt

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