Search clinical trials for: 14C-APD421

Total 2740 results

Acacia Pharma Ltd

Completed

Mass-balance Study of [14C]-APD421 in Healthy Volunteers

Post-operative Nausea and Vomiting

Netherlands
Hoffmann-La Roche

Completed

Mass Balance and Absolute Bioavailability Study of RO7049389 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Acacia Pharma Ltd

Completed

Phase II Dose-ranging Study of APD421 in PONV

Postoperative Nausea and Vomiting

United States, Germany, France
Vivozon, Inc.

Completed

Absorption, Metabolism, Excretion, and Mass Balance Study of [14C]-VVZ-149 in Healthy Adult Male Subjects

Healthy Adult Male

United States
Rachel Lieberman

Terminated

Capsular Tension Rings in Intraocular Lens Rotation

Cataract | Ophthalmoplegia | Ophthalmologic Complication

United States
Acacia Pharma Ltd

Completed

Phase II Proof-of-concept Study of APD421

Chemotherapy-induced Nausea and Vomiting

Denmark, United Kingdom
Acacia Pharma Ltd

Completed

European Phase III Study of APD421 in PONV

PONV

France, Germany
Acacia Pharma Ltd

Completed

Study of APD421 as PONV Treatment (Prior Prophylaxis)

Postoperative Nausea and Vomiting

United States, Germany, France
Acacia Pharma Ltd

Completed

Study of APD421 as PONV Treatment (no Prior Prophylaxis)

Postoperative Nausea and Vomiting

United States, Germany, France
Taisho Pharmaceutical Co., Ltd.

Completed

Mass Balance Study of TS-142 in Healthy Adult Subjects.

Healthy Male Subjects

Japan
Hoffmann-La Roche

Completed

A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)

Solid Tumors

Hungary
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery

Recurrent Pancreatic Carcinoma | Stage IV Pancreatic Cancer | Recurrent Colorectal Carcinoma | Unresectable Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain | Metastatic Solid Neoplasm | Recurrent Solid Neoplasm | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVA Pancreatic... and other conditions

United States
AstraZeneca

Completed

Study to Investigate the Safety Profile of AZD4721 After Single Doses at Different Dose Levels

Safety,Plasma AUC and Cmax, Plasma AUC 0-t, t1/2λz, and Tmax

United Kingdom
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Terminated

A Study to Assess the Hemodynamic Effects, Safety, Tolerability, and Pharmacokinetics of Intravenous APD418 in Adult Participants With Heart Failure With Reduced Ejection Fraction

Acute Heart Failure With Reduced Ejection Fraction

United States, Greece, Serbia, Germany, Poland
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

APN401 in Treating Patients With Melanoma, Kidney Cancer, Pancreatic Cancer, or Other Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific | Stage III Renal Cell Cancer | Recurrent Melanoma | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Melanoma | Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer | Stage IIIA Melanoma | Stage IIIB Melanoma and other conditions

United States
Acacia Pharma Ltd

Completed

Phase IIIb Study of APD421 in Combination as PONV Prophylaxis

PONV

United States, Germany, France
Arena Pharmaceuticals

Completed

Safety and Efficacy Study of APD125 in Patient With Insomnia

Insomnia

United States
Arena Pharmaceuticals

Terminated

Olorinab in Irritable Bowel Syndrome With Predominant Constipation (IBS-C) and Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D) (CAPTIVATE)

Irritable Bowel Syndrome

United States
AstraZeneca

Completed

Study to Investigate Safety, Tolerability and Effect of Multiple Dosing With AZD 4721 and/or With AZD 5069

Chronic Obstructive Pulmonary Disease (COPD).

United Kingdom
United Therapeutics

Completed

Long-term Safety and Efficacy of Ralinepag in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States, Australia, Bulgaria, Czechia, Hungary, Poland, Romania, Serbia, Slovakia, Spain
Arena Pharmaceuticals

Completed

Subjective Study to Assess the Efficacy of APD125 in Patients With Sleep Maintenance Insomnia

Primary Insomnia

United States
Arena Pharmaceuticals

Completed

Tolerability, Pharmacokinetics, and Efficacy of APD371 in Participants With Crohn's Disease Experiencing Abdominal Pain

Abdominal Pain | Crohn's Disease

United States
Acacia Pharma Ltd

Completed

Dose-ranging Study of APD405 in Post-operative Nausea and Vomiting (PONV)

Postoperative Nausea and Vomiting

United States, Switzerland, Germany, France
United Therapeutics

Completed

Safety and Efficacy of APD811 in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States, Australia, Hungary, Bulgaria, Czechia, Poland, Romania, Serbia, Spain
Indivior Inc.

Completed

Single Dose Study of [14C]-IDV184001AN ([14C]-IDV184001) in Healthy Adult Male Participants

Opioid Use Disorder

United States
Arcus Biosciences, Inc.
Gilead Sciences

Completed

A Study Investigating the Safety, Absorption, and Elimination of Radioactively Labeled Etrumadenant, a New Compound in the Treatment of Cancer

Healthy Participants

Netherlands
Biogen
Denali Therapeutics Inc.

Completed

A Study of Mass Balance, Pharmacokinetics, Metabolite Profile, and Metabolite Identification of BIIB122/DNL151 in Healthy Male Subjects

Healthy Volunteers

United States
Laekna Limited

Completed

Human Mass Balance and Biotransformation Study of [14C]Afuresertib

Healthy Volunteer

China
Per-Ola Carlsson
Sana Biotechnology

Not yet recruiting

First-in-human Safety Study of Hypoimmune Pancreatic Islet Transplantation in Adult Subjects With Type 1 Diabetes

Type1diabetes
Athira Pharma
Alturas Analytics, Inc.; Labcorp Drug Development Inc

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-Fosgonimeton (ATH-1017)

Healthy Volunteers

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Human AME Study for Omaveloxolone

Healthy Male Subjects

United States
Cyclerion Therapeutics

Completed

A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Olinciguat in Healthy Male Volunteers

Healthy Volunteers

United States
invIOs GmbH

Recruiting

PBMC-based Leukocyte Immunotherapy (PALINDROM)

Advanced Solid Tumor

Austria
Denovo Biopharma LLC

Completed

A Study of LY2140023 in Healthy Participants

Healthy Participants

United Kingdom
Biogen
Denali Therapeutics Inc.

Completed

A Study to Determine the Absolute Bioavailability of BIIB122/DNL151 in Healthy Subjects

Healthy Volunteers

United States
AstraZeneca
Quotient Sciences

Completed

Study Evaluating the Pharmacokinetic and Mass Balance of Single Dose [14C] AZD5718 in Volunteers

Cardiovascular Disease

United Kingdom
Pfizer
Arvinas Estrogen Receptor, Inc.

Completed

A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults

Healthy

United States
H. Lundbeck A/S

Completed

Study Investigating the Safety and Tolerability of Lu AF88434 in Healthy Young Men

Healthy

Netherlands
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Mass Balance Study of TQB3616

Breast Cancer

China
Cascade Pharmaceuticals, Inc

Completed

Study of [14C]CS0159 in China Healthy Subjects

Primary Biliary Cholangitis

China
Haisco Pharmaceutical Group Co., Ltd.
The First Affiliated Hospital of Soochow University

Completed

Pharmacokinetics, Mass Balance, and Metabolism of [14C]HSK21542 in Healthy Adult Male Volunteers.

Peripheral Analgesic and Anti-itch

China
Sichuan Haisco Pharmaceutical Group Co., Ltd
First Affiliated Hospital of Suzhou Medical College

Completed

Mass Balance and Biotransformation of [14C]HSK7653 in Human

Type II Diabetes

China
Dizal Pharmaceuticals

Completed

Pharmacokinetic and Mass Balance Study of Oral-Administrated [14C]-DZD9008 in Healthy Male Subjects

Healthy Volunteers

United States
Xenon Pharmaceuticals Inc.

Completed

Single-dose Mass Balance Recovery and Metabolite Profile and Identification of 14C-XEN1101

Healthy Volunteers

United Kingdom
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

Mass Balance and Biotransformation Study of [14C]DBPR108 in Human

Healthy Male Subjects

China
Ascentage Pharma Group Inc.
HealthQuest Pharma Inc.

Completed

The Absorption, Metabolism and Excretion of [14C] HQP1351 in Humans

Chronic Myeloid Leukemia (CML)

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

The Mass Balance and Biotransformation of [14C]Donafenib in Healthy Adult Man

Healthy Male Adult

China
Spectrum Pharmaceuticals, Inc

Completed

Study of the Absorption, Metabolism, and Excretion Following a Single Dose of [14C]-Poziotinib in Healthy Male Subjects

Healthy

United States
LG Chem

Completed

Mass Balance Study of [14C]LC350189 in Healthy Volunteers

Hyperuricemia | Gout

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Study to Evaluate the Mass Balance and Biotransformation of [14C]SHR4640 in Chinese Healthy Adult Male Volunteers.

Healthy Adult Male Volunteers

China

Search clinical trials for: 14C-APD421

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Georgia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations