Search clinical trials for: 7.5% hypertonic saline/6% Dextran-70 (HSD)

Total 73 results

University of Washington
National Heart, Lung, and Blood Institute (NHLBI); National Institute of Neurological... and other collaborators

Terminated

Hypertonic Resuscitation Following Traumatic Injury

Shock, Traumatic

United States, Canada
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Terminated

Hypertonic Resuscitation Following Severe Traumatic Brain Injury (TBI)

Brain Injuries, Traumatic

United States, Canada
Oslo University Hospital
BioPhausia

Completed

Hypertonic Saline Dextran in Pediatric Cardiac Surgery

Heart Defects, Congenital | Transposition of Great Vessels | Heart Septal Defects, Ventricular | Endocardial Cushion Defects
University of Washington

Terminated

Hypertonic Modulation of Inflammation Following Injury

Traumatic Brain Injury | Hemorrhagic Shock

United States, Canada
Joseph B. Ciolino, MD
United States Department of Defense

Completed

Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit

Keratolysis

United States
Sunnybrook Health Sciences Centre
Defence Research and Development Canada

Completed

The Toronto Prehospital Hypertonic Resuscitation Head Injury and Multi Organ Dysfunction Trial (TOPHR HIT) (TOPHR HIT)

Traumatic Brain Injury
Heidelberg University
German Center for Lung Research

Completed

Preventive Inhalation of Hypertonic Saline in Infants With Cystic Fibrosis (PRESIS)

Cystic Fibrosis Lung Disease

Germany
The Alfred

Completed

The Long Term Effect of Inhaled Hypertonic Saline (6%) in Patients With Non Cystic Fibrosis Bronchiectasis

Bronchiectasis

Australia
Unity Health Toronto
Defence Research and Development Canada; Sunnybrook Health Sciences Center,...

Completed

Feasibility Trial of Traumatic Brain Injured Patients Randomized in the Prehospital Setting to Either Hypertonic Saline and Dextran Versus Normal Saline (TOPHR HIT)

Brain Injuries

Canada
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury

Shock | Head Injuries, Closed | Respiratory Distress Syndrome, Adult | Shock, Traumatic

United States
Haukeland University Hospital

Withdrawn

"The Effect of Reduced Fluid Load After Cardiac Surgery"

Fluid Overload | Organ Edema | Organ Function
Nicole Hamblett
University of Washington; Dartmouth-Hitchcock Medical Center; Cystic Fibrosis...

Completed

Impact of Discontinuing Hypertonic Saline in People With CF on Highly Effective CFTR Modulators- A SIMPLIFY Sub-Study (SIMPLIFY-HS)

Cystic Fibrosis

United States
Haukeland University Hospital

Completed

Hypertonic Saline-hetastarch in Cardiac Surgery (HH)

Postoperative Cardiorespiratory Failure

Norway
University Hospital Inselspital, Berne

Completed

Hypertonic Saline for Fluid Resuscitation After Cardiac Surgery (HERACLES)

Cardiovascular Diseases | Valvular Heart Disease

Switzerland
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Hypertonic Saline on Mucus Clearance in Children Ages 5-12 With Cystic Fibrosis

Cystic Fibrosis

United States
UPECLIN HC FM Botucatu Unesp
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Lower Limb Sclerotherapy of Reticular Veins and Telangiectasias

Telangiectasis

Brazil
University of Washington, the Collaborative Health...
Cystic Fibrosis Foundation

Completed

Saline Hypertonic in Preschoolers (SHIP)

Cystic Fibrosis

United States, Canada
CF Therapeutics Development Network Coordinating...
National Heart, Lung, and Blood Institute (NHLBI); Cystic Fibrosis Foundation

Completed

Infant Study of Inhaled Saline in Cystic Fibrosis (ISIS)

Cystic Fibrosis

United States, Canada
Nicole Hamblett
University of Washington; Dartmouth-Hitchcock Medical Center; Cystic Fibrosis...

Completed

Impact of Discontinuing Chronic Therapies in People With Cystic Fibrosis on Highly Effective CFTR Modulator Therapy (SIMPLIFY)

Cystic Fibrosis

United States
Fresenius Kabi Japan

Completed

Trial of 6% HES130/0.4

Hemorrhage | Hypovolemia

Japan
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Hypertonic Saline Solution in Heart Failure

Heart Failure | Renal Failure | Hyponatremia

Brazil
Ahmed Mohamed ELbadawy

Unknown

Prophylaxis Versus Treatment for TURP Syndrome.

Transurethral Resection of Prostate Syndrome

Egypt
Meshalkin Research Institute of Pathology of Circulation

Completed

The Efficacy and Safety of Hypertonic Saline in Cardiac Surgery Patients. (ESHHS)

Coronary Artery Disease | Edema

Russian Federation
Montefiore Medical Center

Completed

A Study of Hypertonic Saline for Infants Hospitalized With Bronchiolitis

Bronchiolitis

United States
CF Therapeutics Development Network Coordinating...
Cystic Fibrosis Foundation

Completed

Tolerability of Inhaled Hypertonic Saline in Infants With Cystic Fibrosis (ISIS Pilot)

Cystic Fibrosis

Canada, United States
Hospital Clínico Universitario Lozano Blesa
Hospital Clinic of Barcelona; Universidad San Jorge

Not yet recruiting

Is a Single Daily Session Combining HS + Physio Sufficient to Obtain Long-term Clinical Benefits in Bronchiectasis?

Bronchiectasis | Airway Clearance Impairment

Spain
Groupe Oncologie Radiotherapie Tete et Cou

Completed

Accelerated Radiotherapy and Concomitant Chemo-radiotherapy in HNSCC

Oral Cancer | Oropharynx Cancer | Larynx Cancer | Hypopharynx Cancer

France
University Hospital, Grenoble

Completed

Mannitol Versus Hypertonic Saline Solution in the Treatment of Elevated Intracranial Pressure

Intracranial Hypertension

France
Parion Sciences
Vertex Pharmaceuticals Incorporated

Completed

Clearing Lungs With ENaC Inhibition in Primary Ciliary Dyskinesia (CLEAN-PCD)

Primary Ciliary Dyskinesia

United States, United Kingdom, Netherlands, Denmark, Canada, Italy, Germany, Poland
Belfast Health and Social Care Trust
Queen's University, Belfast

Recruiting

Randomised Open Label Trial of Hypertonic Saline and Carbocisteine in Bronchiectasis (CLEAR) (CLEAR)

Bronchiectasis

United Kingdom
University of Palermo

Completed

Metabolic Effects of Furosemide +HSS in Refractory Ascites

Cirrhosis | Ascites

Italy
Parion Sciences
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United Kingdom, United States, France, Ireland
Taiwan Liposome Company

Completed

Phase IIa, Randomized, Double Blinded, Placebo Controlled, Dose Finding Study for TLC599 in OA Patients

Osteoarthritis of the Knee

Taiwan, Australia
Universidad Autonoma de Baja California

Completed

Pain Reduction Using Two Cold Irrigating Protocols in Teeth With Vital Pulps. (EP18)

Post Operative Pain

Mexico
Hospital General Naval de Alta Especialidad - Escuela...

Unknown

Epinephrine, Dexamethasone and Hypertonic Saline in Bronchiolitis

Bronchiolitis

Mexico
Nektar Therapeutics

Recruiting

NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma

Non-Hodgkin Lymphoma | Relapsed/Refractory Diffuse Large B-cell Lymphoma

United States
M.D. Anderson Cancer Center

Recruiting

Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Recurrent Adult Lymphoblastic Lymphoma | Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Refractory T Acute Lymphoblastic Leukemia | Recurrent T Acute Lymphoblastic Leukemia | Refractory Lymphoblastic Lymphoma

United States
National Cancer Institute (NCI)

Completed

Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

T Acute Lymphoblastic Leukemia | T Lymphoblastic Lymphoma

United States
Fred Hutchinson Cancer Center

Recruiting

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Thiotepa in Treating Patients With Non-malignant Disorders

Non-Neoplastic Hematologic and Lymphocytic Disorder

United States
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States, Canada, Israel, Puerto Rico
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Diffuse Large B-Cell Lymphoma | Acute Myeloid Leukemia | Refractory Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Prolymphocytic Leukemia | Refractory... and other conditions

United States, Germany, Denmark
St. Jude Children's Research Hospital
National University, Singapore

Completed

NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma

Lymphoblastic Lymphoma

United States
Roswell Park Cancer Institute

Active, not recruiting

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Myeloproliferative Neoplasm | Minimal Residual Disease | Graft Versus Host Disease | Severe Aplastic Anemia | Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic Leukemia... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by a Donor Stem Cell Transplant in Treating Patients With Immunodeficiency or Other Nonmalignant Inherited Disorders

Immunodeficiency Syndrome | Non-Cancer Diagnosis

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

90 Y-BC8-DOTA Monoclonal Antibody, Fludarabine Phosphate, and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma

Plasma Cell Myeloma | Refractory Plasma Cell Myeloma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Recurrent Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Childhood Acute Lymphoblastic Leukemia | Plasma Cell Myeloma | Recurrent Diffuse Large B-Cell Lymphoma | Prolymphocytic Leukemia | Refractory Chronic... and other conditions

United States, Denmark
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

High-Dose Y-90-Ibritumomab Tiuxetan Added to Reduced-Intensity Allogeneic Stem Cell Transplant Regimen for Relapsed or Refractory Aggressive B-Cell Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Post-Transplant Lymphoproliferative Disorder | Recurrent Burkitt Lymphoma | Refractory Burkitt Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Erythroid Leukemia | Acute Megakaryoblastic Leukemia | Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Blast Phase Chronic Myelogenous Leukemia,... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Parsaclisib With or Without Polatuzumab Vedotin Plus the Standard Drug Therapy in Patients With Newly Diagnosed, High Risk Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | Indolent Non-Hodgkin Lymphoma | Ann Arbor Stage II Diffuse Large B-Cell Lymphoma | Ann Arbor Stage III Diffuse Large B-Cell Lymphoma | Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | High Grade... and other conditions

United States

Search clinical trials for: 7.5% hypertonic saline/6% Dextran-70 (HSD)

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