Search clinical trials for: ACT-1014-6470

Total 4260 results

Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects

Healthy

Netherlands
Idorsia Pharmaceuticals Ltd.

Completed

A Placebo-controlled Phase 1 Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects

Healthy

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Pharmacokinetics of ACT-1014-6470 in Subjects With Severe Renal Impairment Compared to Control Subjects

Healthy

Germany
Cardix Therapeutics LLC

Not yet recruiting

An Exploratory Safety and Efficacy Clinical Study of CARDIX-101 for the Treatment of Chronic Bradycardia

Bradycardia
Autotelicbio

Recruiting

Evaluation of Efficacy and Safety of ATB-1011+ATB-1012 Co-administration for Essential Hypertension and Type II Diabetes

Diabetes Mellitus, Type 2 | Essential Hypertension

Korea, Republic of
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male Subjects

Healthy

United States
Idorsia Pharmaceuticals Ltd.

Completed

Study in Healthy Subjects to Examine the Safety and Tolerability of ACT-1004-1239 Given as Multiple, Gradually Increasing Doses and to Examine the Effects of ACT-1004-1239 on the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-1004-1239

Healthy

Portugal
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors

Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia

Central Nervous System Neoplasm | Solid Neoplasm | Recurrent Acute Leukemia | Refractory Acute Leukemia | Infantile Fibrosarcoma

United States, Canada
Seoul National University Hospital
National Evidence-Based Healthcare Collaborating Agency; National Clinical... and other collaborators

Completed

Efficacy of Self-education Program for Advanced Care Planning(RCT) for General Population

Healthy

Korea, Republic of
ACADIA Pharmaceuticals Inc.

Completed

ACP-104 in Acutely Psychotic Subjects With Schizophrenia

Schizophrenia

United States
Autotelicbio

Completed

Clinical Trial to Compare Pharmacokinetics After Administration of ATB-101 or Co-administration of ATB-1011 and ATB-1012

Healthy Adult Volunteers

Korea, Republic of
Anbogen Therapeutics, Inc.

Recruiting

Phase 1b/2 Study to Evaluate ABT-101 in Solid Tumor and NSCLC Patients

Non Small Cell Lung Cancer | Advanced Solid Tumor | HER2 Mutations

Taiwan
Applied Molecular Transport

Active, not recruiting

Study of the Efficacy and Safety of AMT-101 in Subjects With Ulcerative Colitis (LOMBARD)

Ulcerative Colitis

United States, Hungary, Ukraine, Germany, United Kingdom, Belarus, Bulgaria, Canada, France, Georgia, Moldova, Republic of, Poland, Russian Federation, Switzerland
Applied Molecular Transport

Completed

Study of the Safety and Efficacy of AMT-101 in Subjects With Pouchitis (FILLMORE)

Pouchitis

United States, Canada, France, Spain, United Kingdom, Germany, Belgium, Hungary, Netherlands, Switzerland
Chang Gung Memorial Hospital

Completed

Comparison of Choosing Free ALT or Free PMT for Reconstruction With Head and Neck Cancer

Head and Neck Cancer | Reconstructive Surgery

Taiwan
Centre Hospitalier Universitaire Vaudois
Lee Ann LAURENT APPLEGATE; Virginie PHILIPPE

Not yet recruiting

Study Comparing Two Methods for the Treatment of Large Chondral and Osteochondral Defects of the Knee

Chondral Defect | Articular Cartilage Defect | Osteochondritis

Switzerland
Applied Molecular Transport

Completed

SAD/MAD Study in Healthy Subjects and Adults With UC to Evaluate Safety, Tolerability, PK, PD of AMT-101 (AURIGA1)

Ulcerative Colitis

Germany, Georgia, Moldova, Republic of, Ukraine
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-389949

Healthy Subjects

Netherlands
National Cancer Institute (NCI)

Terminated

Navitoclax and Vistusertib in Treating Patients With Relapsed Small Cell Lung Cancer and Other Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | Recurrent Lung Small Cell Carcinoma | Stage IIIA Lung Small Cell Carcinoma AJCC v7 | Stage IIIB Lung Small Cell Carcinoma AJCC v7 | Stage IV Lung Small Cell... and other conditions

United States
Idorsia Pharmaceuticals Ltd.

Completed

Pharmacokinetics of Omeprazole and Midazolam When Co-administered With ACT-1014-6470

Healthy | Drug Drug Interaction

Czechia
Idorsia Pharmaceuticals Ltd.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-451840 in Healthy Subjects (Part A)

Healthy

France
Theravance Biopharma

Completed

TD-6450 SAD and MAD in Healthy Subjects

Hepatitis C

United States
Centrexion Therapeutics

Completed

A Placebo-Controlled, Two-Part Study, Oral Dose to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of CNTX-6970 in Healthy Subjects

Chronic Pain | Nociceptive Pain

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)

Healthy
Instituto Vascular BH

Completed

Treatment of Saphenous Vein Reflux With 1920-nm Diode Laser

Varicose Veins

Brazil
University Hospital, Lille

Not yet recruiting

Effect of Attentional Therapy on Post-traumatic Stress Disorder (BATRAUMA)

Post Traumatic Stress Disorder
Azusa Pacific University

Withdrawn

Culturally Tailored ACT for Black Trauma

Anxiety Disorders | Stress Disorders, Traumatic | Anxiety

United States
Karolinska Institutet
Region Stockholm; Forte; Stiftelsen Frimurarna Barnhuset

Active, not recruiting

Internet-delivered ACT (I-Navigator ACT) for Parents of Children With Disabilities

Depression | Stress, Psychological | Intellectual Disability | Anxiety | Neurodevelopmental Disorders | Traumatic Brain Injury | Autism Spectrum Disorder | Parents | Attention Deficit Hyperactivity Disorder | Physical Disability

Sweden
University of Coimbra
Fundação para a Ciência e a Tecnologia

Unknown

iACT With Pain: an ICT-delivered Intervention for Self-management of Chronic Pain (iACT)

Chronic Pain
University College Dublin

Completed

Acceptance and Commitment Therapy (ACT) in Inflammatory Bowel Disease

Inflammatory Bowel Disease

Ireland
Georgia State University

Recruiting

Calling All Dads! Evaluation of APAs ACT Program: Engaging Fathers to Prevent Adverse Childhood Experiences (CAD)

Child Abuse

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease

Stable Coronary Artery Disease

Denmark, Netherlands, Singapore, Canada, United Kingdom, United States, Germany, Sweden
Idorsia Pharmaceuticals Ltd.

Terminated

A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478

Healthy

Germany
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206

Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

Netherlands
George Washington University
University of Oklahoma; Addis Ababa University; Pathfinder International; Overseas... and other collaborators

Active, not recruiting

GAGE Act With Her-Ethiopia Evaluation

Adolescent Behavior | Gender

Ethiopia
Astex Pharmaceuticals, Inc.

Completed

Safety Study to Determine the Maximum Tolerated Dose, Pharmacokinetics and Pharmacodynamics of Oral MP470, a Multitargeted Tyrosine Kinase Inhibitor, in Patients With Solid Malignancies

Solid Tumors

United States
VA Office of Research and Development
University of Alabama, Tuscaloosa

Recruiting

Telehealth Acceptance and Commitment Therapy for Older Veterans Experiencing Pandemic-Related Stress (Pan-ACT)

Psychological Stress

United States
Region Skane

Withdrawn

Acceptance and Commitment Based Group Therapy for Cancer Patients

Cancer | Psychological Distress

Sweden
Aspire Health Science

Unknown

ACT-20 in Patients With Severe COVID-19 Pneumonia

COVID-19 Pneumonia
Assistance Publique Hopitaux De Marseille

Recruiting

EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENCE THERAPY BALLOONS IN BLADDER EXSTROPHY AND INCONTINENT EPISPADIAS PATIENTS (ACT)

Bladder Exstrophy

France
Uppsala University

Terminated

Psychological Treatment in Psychiatric Inpatient Care

Psychosis | Psychiatric Disorder | Psychiatric Hospitalization | Compulsory Psychiatric Care Act | Acceptance & Commitment Therapy

Sweden
OrsoBio, Inc

Recruiting

Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity

Obesity | Healthy Subjects

New Zealand
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects

Healthy Subjects

Netherlands
VA Office of Research and Development

Completed

Telehealth Therapy for Chronic Pain: Comparison of In-person vs. Video-administered ACT for Pain (TTCP)

Chronic Pain

United States
Brigham and Women's Hospital
Massachusetts Institute of Technology

Completed

ACT for High Frequency Migraine; A Virtual Mindfulness Intervention

Migraine

United States
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-389949 in Healthy Subjects

Healthy Subjects

United Kingdom
University of Nottingham

Unknown

Effectiveness of Acceptance and Commitment Therapy Self-Help for Carers of People With Multiple Sclerosis

Carer Stress Syndrome

United Kingdom
Region Skane
Lund University

Recruiting

A Comparison of Two Ultra-brief Interventions in Primary Care for Patients With Anxiety, Depression, and Stress. (RNTACTSweden)

Anxiety | Mental Disorder | Mental Stress | Mental Depression | Mental Health Issue | Rumination - Thoughts

Sweden
Idorsia Pharmaceuticals Ltd.

Completed

Clinical Study to Assess the Pharmacokinetics, Safety, and Tolerability of ACT-129968 in Healthy Subjects

Healthy Subjects

Germany

Search clinical trials for: ACT-1014-6470

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