Search clinical trials for: ACT-541468 (free base)

Total 192 results

Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects

Healthy Subjects

Netherlands
Idorsia Pharmaceuticals Ltd.

Completed

A Clinical Study to Investigate the Food Effect on the Pharmacokinetics of ACT-541468 in Healthy Male Subjects

Healthy

Czechia
Idorsia Pharmaceuticals Ltd.

Completed

A Single Ascending Dose Study of ACT-541468 in Healthy Male Subjects

Healthy Subjects

Netherlands
Idorsia Pharmaceuticals Ltd.

Terminated

A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478

Healthy

Germany
Idorsia Pharmaceuticals Ltd.

Completed

Study of the Way the Body Takes up, Distributes, and Gets Rid of ACT-541468 in Subjects With Abnormal Kidney Function Compared to Healthy Subjects

Healthy | Renal Insufficiency

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effects of ACT-541468 on Nighttime Respiratory Function in Patients With Mild to Moderate Obstructive Sleep Apnea

Obstructive Sleep Apnea

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effects of Daridorexant on Nighttime Breathing in Patients With Shallow or Paused Breath During Sleep

Obstructive Sleep Apnea of Adult

Germany
Idorsia Pharmaceuticals Ltd.

Completed

Efficacy and Safety of ACT-541468 in Elderly Subjects With Insomnia Disorder

Insomnia Disorder

United States, Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate the Effects of ACT-541468 on Respiration in Patients With Moderate Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study of ACT-541468 in Healthy Japanese and Caucasian Subjects

Healthy Subjects

Netherlands
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate the Pharmacokinetics of ACT-541468 in Subjects With Mild, Moderate, and Severe Hepatic Impairment

Hepatic Impairment

Switzerland
M.D. Anderson Cancer Center
Theravance Biopharma

Completed

Study to Evaluate the Safety and Efficacy of Telavancin in the Treatment of Gram Positive Bloodstream Infections in Cancer Patients

Bacteremia | Infection

United States
Idorsia Pharmaceuticals Ltd.

Completed

Efficacy and Safety of ACT-541468 in Adult Subjects With Insomnia Disorder

Insomnia Disorder

United States, Germany, Spain, Hungary, Israel, Sweden
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Drug-drug Interactions Between ACT-541468 and Ethanol in Healthy Subjects

Healthy

Netherlands
Region Skane

Withdrawn

Acceptance and Commitment Based Group Therapy for Cancer Patients

Cancer | Psychological Distress

Sweden
Istituto Auxologico Italiano

Completed

MOTIVOB-(Acceptance and Commitment Therapy Group Intervention for Obesity)Section (MOTIVOB-ACT)

Obesity
ALK-Abelló A/S

Completed

A Dose-response Evaluation of ALK (the Sponsor) Tree Allergy Immunotherapy Tablet

Birch Pollen Allergy

Finland, Netherlands
University of Social Sciences and Humanities, Warsaw
National Science Centre, Poland

Not yet recruiting

The Effect of an Online ACT Intervention on Meaning-Making Process in Cancer Patients Following Hematopoietic Cell Transplantation

Hematopoietic Cell Transplantation Recipient | Acceptance and Commitment Therapy

Poland
University of Cyprus
University of Crete

Unknown

Acceptance and Commitment Therapy and Cognitive Behavioral Therapy for Chronic Pain (ALGEA)

Chronic Pain

Greece
Galapagos NV

Completed

Oral Bioavailability of Two Solid Formulations of GLPG0259.

Healthy

Belgium
University of Aarhus
Karolinska Institutet; Aarhus University Hospital

Completed

Internet-delivered Acceptance and Commitment Therapy for Patients With Health Anxiety

Hypochondriasis
Istituto Auxologico Italiano

Completed

The ACTonHEART Study: Design of a Randomized Controlled Clinical Trial of Acceptance and Commitment Therapy for Cardiac Patients (ACTonHEART)

Cardiovascular Diseases

Italy
Gachon University

Recruiting

Application of the Web-based Acceptance and Commitment Therapy for Depression (ACTION)

Major Depressive Disorder

Korea, Republic of
Karolinska Institutet

Completed

Acceptance and Commitment Therapy (ACT) Self-help to Reduce Stress (ACT)

Stress

Sweden
Bristol-Myers Squibb

Completed

A Study in Healthy Participants Evaluating the Absorption of a BMS-986205 Tablet Into the Bloodstream Compared to a Reference Tablet

Healthy Volunteers

United States
University of Alabama at Birmingham
U.S. Department of Education

Completed

Falls-based Training for Walking Post-Stroke (FBT)

Cerebral Hemiplegia
Fred Hutchinson Cancer Center
Kenya Medical Research Institute; Jhpiego

Recruiting

Pharmacy-based PrEP Delivery in Kenya

Hiv

Kenya
Idorsia Pharmaceuticals Ltd.

Completed

A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-541468 Can Affect the Fate in the Body (Amount and Time of Presence in the Blood) of Rosuvastatin

Healthy Subjects

Czechia
Idorsia Pharmaceuticals Ltd.

Completed

A Clinical Study to Assess Next-day Driving Performance Following Administration of ACT-541468 in Middle-aged and Elderly Subjects

Healthy

Netherlands
Meiji Gakuin University

Recruiting

Group-based Acceptance and Commitment Therapy for Family Caregivers of People With Dementia in Japan

Dementia | Family Caregivers

Japan
Oyster Point Pharma, Inc.

Completed

Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study)

Dry Eye Disease

United States
Contextual Change LLC

Completed

Mindfulness and Acceptance Applied in Colleges Through Web-Based Guided Self-Help (Phase II)

Mental Health

United States
AnHeart Therapeutics Inc.

Completed

A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of DS-6051b

Solid Tumors

United States
Universiti Sains Malaysia
Xinxiang medical university

Not yet recruiting

RCT of Acceptance and Commitment Therapy Versus Mindfulness-based Stress Reduction in Head and Neck Cancer

Cancer of Head and Neck
Hvidovre University Hospital

Completed

Feasibility and Impact of Resistance Training for Sarcopenic Dysphagia

Sarcopenia | Dysphagia

Denmark
University College Dublin

Completed

The Contribution of a Smartphone Application to Acceptance and Commitment Therapy Group Treatment for Smoking Cessation

Smoking

Ireland
Hospital Universitario La Paz

Recruiting

Mindfulness-based Emotional Regulation Versus ACT in Anxiety (MER-ACT)

Anxiety

Spain
The Gerocenter Foundation for Research and Development

Completed

Internet-based Intervention for Enhancing the Psychological Well-being of Elderly Caregivers (CareACT)

Quality of Life | Depressive Symptoms | Psychological Distress

Finland
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Incentive-based Intervention for Smoking Cessation and Prevention in High Schools (Rise Above)

Tobacco Prevention and Cessation

United States
Cadex Genomics

Completed

Development of a Cell Free DNA Assay as a Biomarker for Predicting Early Non-response to Therapy in Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Non-Small Cell Lung Carcinoma

United States, Canada
Cairo University

Not yet recruiting

HEMA-free Universal Adhesives for Restoring Non-carious Cervical Lesions

Universal Adhesive
Idorsia Pharmaceuticals Ltd.

Completed

Pharmacokinetic Interaction Between Diltiazem and ACT-541468 in Healthy Subjects

Healthy Subjects

Germany
Duke University

Withdrawn

Acceptability and Feasibility of an ACT-Based Group to Improve Diabetes Self-Management

Type 1 Diabetes Mellitus
Hvidovre University Hospital

Recruiting

Occupational Therapy Rehabilitation for Frail Elders With Dysphagia

Deglutition Disorders | Dysphagia, Oropharyngeal

Denmark
University of Jyvaskyla
Social Insurance Institution, Finland; The Gerocenter Foundation for Research...

Completed

Web-based ACT to Support Parents With Children With Chronic and Developmental Conditions (Uupu)

Quality of Life | Depressive Symptoms | Psychological Distress | Burnout Syndrome

Finland
University of Oklahoma

Recruiting

Sensory-Play Based (SenPlay) Intervention for Young Children With or At Risk for ADHD

Attention Deficit Hyperactivity Disorder

United States
Mead Johnson Nutrition

Completed

The Evaluation of Infant Formulas Fed to Infants With Common Feeding Problems

Common Infant Feeding Problems

United States, Canada
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Moi University

Completed

Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector

Fever | Malaria

Kenya
US Department of Veterans Affairs

Completed

Behavioral Treatments for Chronic Pain

Intractable Pain

United States
Istituto Auxologico Italiano

Recruiting

mACTonHEALTH: Psychological Flexibility and Activity Tracker - Protocol (ACTonHEALTH)

Health Behavior

Italy

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