Search clinical trials for: AMG 986 Oral Dose Level A or matching Placebo

Total 73 results

Vertex Pharmaceuticals Incorporated

Completed

Study of VX-985 in Subjects With Chronic Hepatitis C

Chronic Hepatitis C

United States
Genexine, Inc.

Completed

Safety and Tolerability of GX-P1 in Healthy Male Volunteers

Autoimmune Diseases

Korea, Republic of
F2G Biotech GmbH
SimbecRresearch Ltd.

Completed

Multiple Ascending Oral Dose Study of F901318 in Healthy Subjects (ORALMAD)

Invasive Aspergillosis

United Kingdom
Centrexion Therapeutics

Completed

Safety, Tolerability & Pharmacokinetics Study of CNTX-6016 in Healthy Subjects and Subjects With PDN

Painful Diabetic Neuropathy

United States
Pfizer

Completed

Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Orally

Fungal Infection

Netherlands
Sun Pharma Advanced Research Company Limited

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SPARC1316

Asthma

United Kingdom
HK inno.N Corporation

Unknown

A Study to Explore Pharmacokinetics/Pharmacodynamics and Safety of Tegoprazan BID Dosing in Healthy Subjects

Healthy

Korea, Republic of
Applied Molecular Transport

Completed

Study of the Safety and Efficacy of AMT-101 in Subjects With Pouchitis (FILLMORE)

Pouchitis

United States, Canada, France, Spain, United Kingdom, Germany, Belgium, Hungary, Netherlands, Switzerland
Stragen France

Completed

First-In-Human PainCart Study for STR-324

Pain

Netherlands
GlaxoSmithKline

Terminated

A First Time in Human Study Exploring Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2618960 in Healthy Volunteers and Patients With Relapsing Remitting Multiple Sclerosis (RRMS)

Multiple Sclerosis, Relapsing-Remitting

United Kingdom
Suzhou Kintor Pharmaceutical Inc,

Completed

To Evaluate Efficacy, Safety, and Tolerability of KX-826 in Male Subjects With Androgenetic Alopecia

Alopecia | Male Pattern Hair Loss

United States
AstraZeneca

Recruiting

Zibotentan and Dapagliflozin Combination, EvAluated in Liver Cirrhosis (ZEAL Study) (ZEAL)

Liver Cirrhosis

Spain, Denmark, Germany, United States, China, Australia, Belgium, Netherlands, Switzerland, Austria, Taiwan, Canada, Czechia
Novartis Pharmaceuticals

Completed

Assess Bronchodilator Effect QVM149 Dosed Either in the Morning or Evening Compared to Placebo in Patients With Asthma (QVM149)

Asthma

Germany, Netherlands, United Kingdom
Fuji Yakuhin Co., Ltd.

Completed

Study of FYU-981 in Hyperuricemia With or Without Gout

Hyperuricemia

Japan
CHA University
Merck Sharp & Dohme LLC

Completed

Response of FeNO, Small Airway Dysfunction and Lung Heterogeneity to 2-week Montelukast Treatment in Asthmatic Children.

Mild Persistent Asthma
Agios Pharmaceuticals, Inc.

Completed

A Phase I Study of AG-348 in Healthy Volunteers (AG-348 SAD)

Healthy Volunteer

United States
Shanghai Pharmaceuticals Holding Co., Ltd

Completed

The Tolerability and Pharmacokinetics of Multiple Doses of SPH3127 in Chinese Healthy People

Hypertension

China
Idorsia Pharmaceuticals Ltd.

Terminated

A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478

Healthy

Germany
Forest Laboratories

Completed

Safety, Efficacy and Tolerability of Vilazodone in Patients With Generalized Anxiety Disorder (VLZ-MD-06)

Generalized Anxiety Disorder

United States
Rhythm Pharmaceuticals, Inc.

Recruiting

A Study of RM-718 in Healthy Subjects and in Patients With HO

Hypothalamic Obesity

United States
Northwestern University
University of Iowa; University of Rochester; Michael J. Fox Foundation for Parkinson...

Completed

Nilotinib in Parkinson's Disease (NILO-PD)

Parkinson Disease

United States
PhaseBio Pharmaceuticals Inc.

Completed

Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Study to Assess Safety, Tolerability, PK and PD Response of PB1023 Injection Following Single and Multiple SQ Doses in Adults With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Danish Headache Center

Completed

Effect of Riocigaut on Cerebral Vasodilation and Headache Induction in Healthy Volunteers

Headache

Denmark
Galderma R&D

Completed

Safety and Efficacy of AbobotulinumtoxinA for the Treatment of Glabellar Lines

Glabellar Frown Lines

United States
Forest Laboratories
Ironwood Pharmaceuticals, Inc.

Terminated

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7-17 Years, With Irritable Bowel Syndrome With Constipation (LIN-MD-63)

Irritable Bowel Syndrome With Constipation

United States, Canada
The Deutsche Diabetes Forschungsgesellschaft e.V.
Novo Nordisk A/S; Boehringer Ingelheim; Federal Ministry of Health, Germany; German... and other collaborators

Recruiting

Combined Active Treatment in Type 2 Diabetes With NASH (COMBAT_T2_NASH)

Type 2 Diabetes | Non-alcoholic Fatty Liver Disease (NAFLD) | Non-alcoholic Steatohepatitis (NASH)

Germany, Austria
Amgen

Completed

TRINOVA-1: A Study of AMG 386 or Placebo, in Combination With Weekly Paclitaxel Chemotherapy, as Treatment for Ovarian Cancer, Primary Peritoneal Cancer and Fallopian Tube Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States, France, Italy, Spain, United Kingdom, Belgium, Canada, Poland, Switzerland, Korea, Republic of, Russian Federation, Hong Kong, Portugal, South Africa, Israel, Romania, Bulgaria, Greece, Australia, Sweden, Japan, Latvia and more
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited

Completed

Safety and Efficacy of Telaprevir in Combination With Peginterferon Alfa-2a and Ribavirin in Subjects Co-Infected With Hepatitis C Virus (HCV) and HIV

HIV Infections | Hepatitis C

France, Spain, United States, Germany
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants

Healthy

Belgium
Hadassah Medical Organization

Terminated

TSO in Pediatric Autistic Spectrum Disorders (TSO)

Autistic Spectrum Disorders

Israel
University Hospital, Antwerp

Completed

Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex (SUDIA)

Muscle Weakness | Muscle Fatigue | Diaphragmatic Dysfunction

Belgium
Stanford University

Withdrawn

Investigate Efficacy & Safety of RO4995819 vs. Placebo as Adjunct Tx in Patients w/Major Depressive Disorder

Depression | Major Depressive Disorder
Tris Pharma, Inc.
Forest Laboratories

Completed

Efficacy and Safety of GRT6005 in Patients With Chronic Low Back Pain.

Low Back Pain

Austria, Belgium, Denmark, Finland, Germany, Hungary, Netherlands, Poland, Spain, Sweden, United Kingdom
Ferring Pharmaceuticals

Completed

LutrePulse Hypogonadotropic Hypogonadism

Primary Amenorrhea With Hypogonadotropic Hypogonadism

United States, Canada
McMaster University
MediPharm Labs Corp

Withdrawn

Cannabinoids for the Treatment of Anxiety Disorders: An 8-Week Pilot Study

Generalized Anxiety Disorder | Social Anxiety Disorder | Panic Disorder | Agoraphobia

Canada
Assistance Publique - Hôpitaux de Paris

Completed

Mechanical Bowel Preparation and Oral Antibiotics Before Rectal Cancer Surgery (PREPACOL2)

Rectal Cancer Surgery

France
Theravance Biopharma

Completed

Thorough QT Study to Evaluate Ampreloxetine in Healthy Subjects

Symptomatic Neurogenic Orthostatic Hypertension | nOH

United States
Stallergenes Greer

Completed

Dose Ranging Study of SLIT Tablets of House Dust Mite Allergen Extracts (HDM) in Adults With HDM-associated Allergic Asthma

Asthma | House Dust Mite Allergy

France, Germany, Poland
Centre Hospitalier Universitaire Dijon

Completed

Randomized Trial Sorafenib-Pravastatin Versus Sorafenib Alone for the Palliative Treatment of Child-Pugh A Hepatocellular Carcinoma

Child-Pugh A Hepatocellular Carcinoma

France
Roger K. Pitman, MD

Completed

Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments

Post-traumatic Stress Disorder

United States
Forest Laboratories

Completed

Safety, Efficacy and Tolerability of Vilazodone in (GAD) Generalized Anxiety Disorder

Generalized Anxiety Disorder

United States
Angion Biomedica Corp
Quotient Sciences

Not yet recruiting

Study Developed to Evaluate the Effect of ANG-3777 on QT/QTc Interval

Healthy Volunteer

United States
Angiogenix

Unknown

Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease

Peripheral Arterial Disease | Intermittent Claudication

Russian Federation
University of Texas Southwestern Medical Center
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT-2) for Methamphetamine Use Disorder (ADAPT-2)

Methamphetamine Use Disorder

United States
QuantumLeap Healthcare Collaborative

Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer (I-SPY)

Breast Cancer | Breast Neoplasms | Breast Tumors | HER2-positive Breast Cancer | Angiosarcoma | Locally Advanced Breast Cancer | HER2-negative Breast Cancer | TNBC - Triple-Negative Breast Cancer | Hormone Receptor Positive Tumor | Hormone Receptor Negative Tumor | Early-stage Breast Cancer

United States
Marion Coe
National Institute on Drug Abuse (NIDA)

Completed

Sedative-Anxiolytic Effects on Simulated Driving Performance

Psychomotor Impairment

United States
Masonic Cancer Center, University of Minnesota

Recruiting

RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial

Lung Cancer | Adenocarcinoma of Lung

United States
Phramongkutklao College of Medicine and Hospital
Silpakorn University

Recruiting

Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital

Carbapenem Resistant Klebsiella Pneumoniae

Thailand
Pfizer

Completed

Study to Assess Pharmacokinetics, Safety and Tolerability of PF-04965842 in Chinese Healthy Participants

HEALTHY

China
Hoffmann-La Roche

Completed

Study to Investigate the Effect of Balovaptan on the QTC Interval in Healthy Subjects

Healthy Volunteers

United States

Search clinical trials for: AMG 986 Oral Dose Level A or matching Placebo

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