Search clinical trials for: ASP0456

Total 56 results

Astellas Pharma Global Development, Inc.

Completed

A Dose Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASP4058 Following Single Oral Doses

Healthy Subjects | Pharmacokinetics of ASP4058 | Food Effect of ASP4058

United States
Northwestern University
Astellas Pharma Inc

Terminated

A Pilot Study to Assess the Safety and Efficacy of Alefacept in de Novo Kidney Transplant Recipients

Transplant; Failure, Kidney

United States
Astellas Pharma Inc

Completed

A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation

Chronic Constipation

Japan
Astellas Pharma Global Development, Inc.
Seagen Inc.

Completed

A Study of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects With Metastatic Urothelial Cancer and Other Malignant Solid Tumors That Express Nectin-4

Metastatic Urothelial Cancer and Other Malignant Solid Tumors

United States, Canada
Astellas Pharma Inc

Completed

A Study to Evaluate Dose Responses of Efficacy and Safety of ASP0456 in Patient With Chronic Constipation

Chronic Constipation

Japan
Astellas Pharma Inc

Completed

Phase III Study to Evaluate the Efficacy and Safety of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome

Irritable Bowel Syndrome With Constipation (IBS-C)

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate Safety of Multiple Dose of ASP0456 in Healthy Subjects

Healthy | Pharmacokinetics of ASP0456

Japan
Astellas Pharma Inc

Completed

A Safety and Pharmacokinetics Study of ASP0456 in Healthy Subjects

Healthy | Pharmacokinetics of ASP0456

Japan
Astellas Pharma Inc

Completed

Post-marketing Surveillance of Linaclotide Tablet in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation (Excluding Constipation Due to Organic Diseases)

Irritable Bowel Syndrome With Constipation (IBS-C) | Chronic Constipation (CC) (Excluding Constipation Due to Organic Diseases)

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate the Effect of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome

Constipation-predominant Irritable Bowel Syndrome (IBS-C)

Japan
Astellas Pharma Global Development, Inc.

Completed

A Phase I Study to Compare 3 Different Strengths of an Extended Release Formulation of ASP015K to an Immediate Release Formulation of ASP015K

Healthy Volunteers | Pharmacokinetics of ASP015K | Food Effect

United States
Astellas Pharma Inc
Biogen

Completed

Community Based Trial for AMEVIVE®

Moderate to Severe Chronic Plaque Psoriasis

United States
Astellas Pharma Inc
Biogen

Completed

Open-label Study to Evaluate Safety of Multiple Courses of IM Alefacept During Treatment of Chronic Plaque Psoriasis

Psoriasis

Belgium, Spain, Germany, United States, France, Canada, Denmark, Netherlands, United Kingdom
Astellas Pharma Inc

Completed

Safety and Pharmacokinetics (PK) of Alefacept in Adolescent Subjects With Moderate to Severe Psoriasis

Psoriasis

United States, Bulgaria, Latvia
Astellas Pharma Inc

Terminated

AMEVIVE® Pregnancy Registry

Pregnancy

United States
Astellas Pharma Inc

Terminated

Assessment and Tracking of Long-term Alefacept Safety (ATLAS)

Psoriasis

United States, Canada
Astellas Pharma Inc

Completed

A Study of Pharmacokinetics and Safety of Alefacept in Caucasian and Japanese Healthy Volunteers

Pharmacokinetics of Alefacept

United States
Astellas Pharma Inc
Biogen

Completed

A Study to Assess the Efficacy and Safety of Two Dosing Regimens of Alefacept in Subjects Weighing Between 100kg and 150kg With Moderate to Severe Chronic Plaque Psoriasis

Chronic Plaque Psoriasis

United States, Canada
Astellas Pharma Inc
Biogen

Completed

A Study to Assess the Efficacy and Safety of Alefacept in Psoriasis Patients for Whom Conventional Treatment is Ineffective or Inappropriate

Chronic Plaque Psoriasis

United States, Austria, Germany, Belgium, Canada
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Terminated

Assess the Long-term Effectiveness and Safety of Amevive (Alefacept) in Subjects With Moderate to Severe Chronic Plaque Psoriasis (AWARE-2)

Chronic Plaque Psoriasis

Canada
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Renal Function and Subjects With Normal Renal Function

Patients With Impaired Renal Function

Japan
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

A Study to Assess the Relative Bioavailability Between Two ASP015K Tablets and the Food Effect of a New Tablet in Healthy Adult Subjects

Healthy Subjects | Bioavailability of ASP015K | Pharmacokinetics of ASP015K | Food Effect of ASP015K

United States
Astellas Pharma Inc

Completed

A Single Oral Dose Study to Compare the Bioavailability Between Two Different Tablet Formulations and Assess if There is a Food Effect With the New Formulation

Healthy Subjects | Bioavailability of ASP015K | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Completed

A Study to Assess the Pharmacokinetics of ASP015K in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K

Healthy Subjects | Pharmacodynamics | Pharmacokinetics of ASP015K

United States
Astellas Pharma China, Inc.

Completed

A Study to Evaluate the Pharmacokinetics and Safety of ASP015K in Healthy Chinese Subjects

Healthy Volunteers

China
Astellas Pharma Inc

Completed

A Study to Continue ASP015K Treatment to Rheumatoid Arthritis Patients Who Completed Phase IIb Study or Phase III Study of ASP015K

Arthritis, Rheumatoid

Japan, Korea, Republic of, Taiwan
Astellas Pharma Inc

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Completed

Assess the Efficacy and Safety of Alefacept With Narrow Band Ultraviolet B Phototherapy (nbUVB) vs. Alefacept Alone in Chronic Plaque Psoriasis Subjects

Plaque Psoriasis

Canada
Astellas Pharma Inc

Completed

Single and Multiple Oral Administration Study of ASP015K in Healthy Nonelderly Volunteers

Healthy Volunteer | Pharmacokinetics of ASP015K

Japan
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Poland, Czechia, Bulgaria, Hungary, Mexico
Astellas Pharma Inc

Completed

A Single Oral Dose Study of ASP015K in Healthy Volunteers Assessing the Relative Bioavailability Across Three Tablet Strengths From a New Formulation of ASP015K

Healthy Subjects | Bioavailability of ASP015K | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Hepatic Function

Patients With Impaired Hepatic Function

Japan
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K in Healthy Subjects

Healthy Volunteers | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Recruiting

Japan Post-Marketing Surveillance for Peficitinib to Assess Safety and Effectiveness in the Patients With Rheumatoid Arthritis

Rheumatoid Arthritis (RA)

Japan
Astellas Pharma Inc

Completed

Bioequivalence Evaluation of a New and Current Tablet of ASP015K

Healthy Volunteers

Japan
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Tacrolimus in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Completed

A Study to Evaluate the Efficacy and Safety of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects

Arthritis, Rheumatoid

Japan
Astellas Pharma Inc

Completed

A Study to Explore Efficacy and Safety of ASP015K in Subjects With Moderate to Severe Psoriasis

Psoriasis

United States
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

A Study to Evaluate the Long-term Safety and Efficacy of ASP015K in Subjects Previously Enrolled in a Phase 2 ASP015K Rheumatoid Arthritis Study

Arthritis, Rheumatoid

United States, Belgium, Bulgaria, Colombia, Czechia, Hungary, Mexico, Poland
Astellas Pharma Inc

Completed

A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Metformin

Healthy Subjects

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate the Drug Interaction of ASP015K and Tacrolimus

Healthy | Pharmacokinetics of ASP015K and Tacrolimus

United States
Astellas Pharma Inc

Completed

Study to Evaluate the Immune Response to Pneumococcal Vaccine in Alefacept-treated Adults With Chronic Plaque Psoriasis

Chronic Plaque Psoriasis

United States, Canada
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

Drug-Drug Interaction Study Evaluating Effects of ASP015K on Rosuvastatin

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Mycophenolate Mofetil in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
Astellas Pharma China, Inc.

Completed

A Study to Assess Safety and Efficacy of ASP015K in Participants With Rheumatoid Arthritis (RA) Who Had an Inadequate Response or Intolerance to Methotrexate (MTX)

Rheumatoid Arthritis (RA)

China, Korea, Republic of, Taiwan
Astellas Pharma Inc

Completed

A Study to Evaluate Safety and Efficacy of ASP015K in Patients With Rheumatoid Arthritis (RA) Who Had an Inadequate Response to DMARDs

Rheumatoid Arthritis

Japan, Korea, Republic of, Taiwan
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

A Study to Evaluate the Effect of Verapamil on the Pharmacokinetics of ASP015K in Healthy Adult Subjects

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Completed

A Study to Assess the Bioavailability of ASP015K

Healthy

United Kingdom
Astellas Pharma Inc
Biogen

Completed

A Placebo-controlled Study With an Extension Examining the Safety and Efficacy of Alefacept in Psoriatic Arthritis

Psoriatic Arthritis

Poland, Canada, United States, Russian Federation, Germany

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