Search clinical trials for: ASP1941

Total 69 results

Astellas Pharma Inc

Completed

Study of ASP1948, Targeting an Immune Modulatory Receptor, in Japanese Patients With Advanced Solid Tumors

Locally Advanced (Unresectable) or Metastatic Solid Tumor Malignancies

Japan
Guangdong Zhongsheng Pharmaceutical Co., Ltd.

Unknown

A Phase 1 Study of ZSP1241 in Participants With Advanced Solid Tumors

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Cholangiocarcinoma

China
Jasper Therapeutics, Inc.

Recruiting

JSP191 (Briquilimab) in Subjects With LR-MDS

Lower-risk Myelodysplastic Syndrome

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Assess the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of ASP6981 in Subjects With Schizophrenia

Schizophrenia

United States
Ascendo Biotechnology Co., Ltd.

Not yet recruiting

Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ASD141

Metastatic Solid Tumor
Astellas Pharma Inc

Completed

A Study to Compare the Oral Absorption of ASP1941 Among Two Types of Tablets

Healthy | Plasma Concentration of ASP1941

Japan
Astellas Pharma Inc

Completed

A Study to Investigate the Effect of Food on the Absorption, Distribution and Elimination of ASP1941

Healthy | Pharmacokinetics of ASP1941

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate the Effect of ASP1941 in Combination With Metformin in Adult Patients With Type 2 Diabetes Mellitus (BALANCE)

Type 2 Diabetes Mellitus

United States, Hungary, Poland, Romania, Italy, United Kingdom
Astellas Pharma Inc

Completed

Drug to Drug Interaction Study With ASP1941 and Metformin

Type 2 Diabetes Mellitus

Hungary, Poland, Slovakia, Netherlands
Astellas Pharma Inc

Completed

A Study to Assess the Long-term Safety and Efficacy of ASP1941 in Japanese Diabetic Patients

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

A Study of ASP1941 in Japanese Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Europe B.V.

Completed

A Phase 1 Study to Investigate the Mechanism of Action of Ipragliflozin

Type 2 Diabetes Mellitus

Germany
Astellas Pharma Inc

Completed

Multiple Dose Escalating Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP1941

Healthy

Netherlands
Astellas Pharma Inc

Completed

A Study to Assess the Effect of Hepatic Function on the Pharmacokinetics and Safety of ASP1941

Liver Disease

United States
Astellas Pharma Inc

Completed

A Study to Assess Safety and Tolerability of ASP1941 After Single and Repeated Administration in Healthy Subjects

Healthy Volunteer | Pharmacokinetics of ASP1941

Japan
Astellas Pharma Inc

Completed

A Study to Assess the Pharmacokinetics, Pharmacodynamics of ASP1941 in Diabetes Mellitus Patients With Renal Impairment

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

A Study of ASP1941 in Participants With Type 2 Diabetes Mellitus

Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

A Study to Assess Efficacy and Safety of ASP1941 in Diabetic Patients With Renal Impairment

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

Mass Balance Study of ASP1941

Healthy Subjects

Netherlands
Jasper Therapeutics, Inc.

Recruiting

A Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients With Chronic Inducible Urticaria (CIndU) Who Remain Symptomatic Despite Treatment With H1- Antihistamines (SPOTLIGHT)

Chronic Inducible Urticaria

Germany
Astellas Pharma Inc

Completed

A Study to Evaluate Long-term Safety and Efficacy of ASP1941 in Diabetes Patients

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

A Study to Assess the Safety and Tolerability of ASP1941 in Adults With Type 2 Diabetes Mellitus.

Diabetes Mellitus, Type 2

United States
Astellas Pharma Inc

Completed

Renal Impairment Study With ASP1941

Type 2 Diabetes Mellitus

Hungary, Poland, Czechia, Slovakia
Astellas Pharma Global Development, Inc.

Completed

Study of the Pharmacokinetics of ASP1941 and the Effect on Glucose Concentrations in Male and Female Young and Elderly Healthy Adults

Healthy Volunteers | Pharmacokinetics of ASP1941

United States
Astellas Pharma Europe B.V.

Completed

Absolute Bioavailability Study With Ipragliflozin

Healthy Subjects | Bioavailability of Ipragliflozin

United Kingdom
Astellas Pharma Inc

Completed

First in Men Study of Single Oral Doses of ASP1941 in Healthy Subjects

Healthy

United Kingdom
Astellas Pharma Inc

Completed

Study of Ipragliflozin in Patients With Type 2 Diabetes Mellitus Receiving Insulin Therapy

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc
Astellas Pharma Taiwan, Inc.

Completed

A Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of ASP1941 in Healthy Male Taiwanese Subjects

Healthy | Pharmacokinetics of ASP1941

Taiwan
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of ASP1941 in Japanese Type 2 Diabetes Patients

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

Pharmacodynamics, Pharmacokinetics, and Safety of ASP1941 in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Japan
National Institute of Allergy and Infectious Diseases...

Recruiting

Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD)

Chronic Granulomatous Disease | CGD

United States
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Metformin in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate the Effect of ASP1941 in Adult Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States, India, Philippines, Colombia, Mexico
Astellas Pharma Korea, Inc.

Completed

A Study to Assess the Efficacy and Safety of ASP1941 in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin

Type 2 Diabetes Mellitus

Korea, Republic of
Astellas Pharma Global Development, Inc.
Merck Sharp & Dohme LLC

Completed

A Study of ASP1951 in Subjects With Advanced Solid Tumors

Advanced Solid Tumors

United States, Korea, Republic of, Canada, Taiwan
Astellas Pharma Inc

Completed

Post-Marketing Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Ipragliflozin in Combination With GLP-1 Receptor Agonists in Japanese Patients With Type 2 Diabetes Mellitus (T2DM)

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of Ipragliflozin in Combination With Insulin in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Japan
Jasper Therapeutics, Inc.

Recruiting

JSP191 Antibody Conditioning Regimen in MDS/AML Subjects Undergoing Allogenic Hematopoietic Stem Cell Transplantation

MYELODYSPLASTIC SYNDROME; MDS | ACUTE MYELOID LEUKEMIA; AML

United States
Astellas Pharma Inc

Completed

Drug-drug Interaction Study With ASP1941 and Glimepiride

Healthy Subjects

Netherlands
Astellas Pharma Inc

Completed

Specified Drug Use Results Survey of Ipragliflozin Treatment in type2 Diabetes Patients (STELLALONGTERM)

Type 2 Diabetes

Japan
Astellas Pharma Inc

Completed

A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Pioglitazone Hydrochloride When Given Together to Healthy Subjects

Healthy | Pharmacokinetics of ASP1941

United States
Astellas Pharma Inc

Completed

A Study of ASP1941 in Combination With Insulin in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Japan
Astellas Pharma Global Development, Inc.
Kyowa Kirin Co., Ltd.

Completed

Study of ASKP1240 After a Single Intravenous Dose at Escalating Dose Levels in Healthy Subjects

Healthy Volunteers | Pharmacokinetics of ASKP1240

United States
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Metformin in Asian Diabetes Patients

Type II Diabetes Mellitus

Taiwan, Korea, Republic of
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Pioglitazone in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Inc

Completed

A Study to Assess Safety and Efficacy of ASP1941 in Combination With Nateglinide in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Japan
Astellas Pharma Europe B.V.

Completed

Drug to Drug Interaction Study With Ipragliflozin and Furosemide

Healthy Subjects | Pharmacokinetics of Ipragliflozin

United Kingdom
Jasper Therapeutics, Inc.

Recruiting

Dose Escalation Trial Of Safety, Pharmacokinetic/Pharmacodynamic And Preliminary Clinical Activity of Briquilimab In Adult Patients With Chronic Spontaneous Urticaria (CSU) (BEACON)

Chronic Spontaneous Urticaria

United States
Astellas Pharma Inc

Completed

Examination of Plasma Concentrations and Safety in Chronic Kidney Disease Patients Undergoing Hemodialysis

Patients on Stable Chronic Maintenance Dialysis Who Are Receiving Hemodialysis Therapy | Pharmacodynamics of ASP7991 | Pharmacokinetics of ASP7991

Japan
Astellas Pharma Global Development, Inc.
Merck Sharp & Dohme LLC

Completed

A Study of ASP1948, Targeting an Immune Modulatory Receptor as a Single Agent and in Combination With a PD-l Inhibitor (Nivolumab or Pembrolizumab) in Subjects With Advanced Solid Tumors

Advanced Solid Tumors

United States, Korea, Republic of, Taiwan, Canada, Italy, Japan, Portugal, Spain, United Kingdom

3

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