Search clinical trials for: AVI-4658 (Eteplirsen)

Total 1122 results

Sarepta Therapeutics, Inc.

Completed

Efficacy, Safety, and Tolerability Rollover Study of Eteplirsen in Subjects With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD)

United States
Sarepta Therapeutics, Inc.

Completed

Study of Eteplirsen in Young Participants With Duchenne Muscular Dystrophy (DMD) Amenable to Exon 51 Skipping

Duchenne Muscular Dystrophy

Belgium, France, Italy, United Kingdom
Sarepta Therapeutics, Inc.

Completed

Safety Study of Eteplirsen to Treat Early Stage Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD)

United States
Sarepta Therapeutics, Inc.

Terminated

A Study to Evaluate Safety, Tolerability, and Efficacy of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) Who Have Completed Study 4658-102 (NCT03218995)

Duchenne Muscular Dystrophy

Belgium, France, Italy, United Kingdom
Sarepta Therapeutics, Inc.

Completed

Study of Eteplirsen in DMD Patients (PROMOVI)

Duchenne Muscular Dystrophy (DMD)

United States
Sarepta Therapeutics, Inc.
British Medical Research Council

Completed

Dose-Ranging Study of AVI-4658 to Induce Dystrophin Expression in Selected Duchenne Muscular Dystrophy (DMD) Patients

Duchenne Muscular Dystrophy

United Kingdom
Sarepta Therapeutics, Inc.

Active, not recruiting

A Study to Compare Safety and Efficacy of a High Dose of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON)

Muscular Dystrophy, Duchenne

United States, Korea, Republic of, India, Slovenia, Turkey, United Kingdom, Germany, Switzerland, Spain, Czechia, France, Serbia, Taiwan, Netherlands, Mexico, Colombia, Denmark, New Zealand, Norway, Greece, Hungary, Ireland, Italy, Jo... and more
Sarepta Therapeutics, Inc.

Completed

Efficacy Study of AVI-4658 to Induce Dystrophin Expression in Selected Duchenne Muscular Dystrophy Patients

Duchenne Muscular Dystrophy

United States
Sarepta Therapeutics, Inc.

Completed

Safety Study of Eteplirsen to Treat Advanced Stage Duchenne Muscular Dystrophy

Muscular Dystrophy, Duchenne

United States
Kevin Flanigan
Sarepta Therapeutics, Inc.

Completed

A 48-Week, Open Label, Study to Evaluate the Efficacy and Safety of AMONDYS 45, EXONDYS 51, VYONDYS 53 in Subjects With DuchenneMuscular Dystrophy Carrying Eligible DMD Duplications.

Duchenne Muscular Dystrophy

United States
Imperial College London
Sarepta Therapeutics, Inc.; Department of Health, United Kingdom

Completed

Safety and Efficacy Study of Antisense Oligonucleotides in Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

United Kingdom
Columbia University
National Institute on Aging (NIA)

Completed

Comparison of AVF Versus AVG in Elderly Patients Starting Dialysis

Chronic Kidney Disease | Endstage Renal Disease

United States
Kuopio University Hospital

Terminated

Surgical Pulmonary Vein Isolation Efficiency Study (FIN-PVI)

Coronary Artery Disease | Paroxysmal Atrial Fibrillation

Finland
University Medical Center Groningen
Stichting Hemato-Oncologie voor Volwassenen Nederland

Recruiting

Comparison of Point-of-care Produced CAR T-cell With Commercial CAR T-cells in Patients With R/R LBCL (HOVON161)

NHL | DLBCL - Diffuse Large B Cell Lymphoma

Netherlands
Mario Negri Institute for Pharmacological Research

Recruiting

Acoustic Analysis of VA Sounds (VAsound)

End Stage Renal Disease | Hemodialysis Access Failure

Italy
University of Pittsburgh

Terminated

Trial of Fistula Versus Graft in Elderly Patients

End Stage Renal Disease | Arteriovenous Fistula | Arteriovenous Graft

United States
Ono Pharmaceutical Co. Ltd

Completed

Single Ascending Dose Study to Assess the Safety, Tolerability, PK and PD of ONO-4685 in Japanese and Caucasian Healthy Adult Male Subjects

Healthy Volunteers

Japan
Sunovion

Completed

Safety, Pharmacokinetics and Pharmacodynamics of DSP-8658 in Patients With Type 2 Diabetes Mellitus and Healthy Adults

Type 2 Diabetes Mellitus

United States
Sarepta Therapeutics, Inc.

Terminated

Safety and Efficacy Study of AVI-5126 When Used on Vein Grafts Before Use in Heart by-Pass Graft Surgery (CABG)

Cardiovascular Disease | Coronary Artery Bypass

Ukraine
Sarepta Therapeutics, Inc.

Completed

Pharmacokinetic Study of a Single Dose of AVI-4065 in Cerebral Spinal Fluid

Encephalitis

United States
Sarepta Therapeutics, Inc.

Terminated

Study of AVI-4065 in Healthy Volunteers and Chronic Active HCV Patients

Hepatitis C
Merck Sharp & Dohme LLC

Completed

A Single-Dose Study of the Pharmacokinetics of Vibegron (MK-4618) in Adults With Hepatic Insufficiency (MK-4618-013)

Overactive Bladder
IRCCS Policlinico S. Donato

Recruiting

OUTcomes Evaluation of Current Therapeutic STrategies for Severe Aortic Valve steNosis anD the agING Population in ITALY (OUTSTANDING)

Aortic Valve Stenosis

Italy
Sarepta Therapeutics, Inc.
United States Department of Defense

Completed

Safety Study of Single Administration Post-exposure Prophylaxis Treatment for Marburg Virus

Marburg Hemorrhagic Fever

United States
Chinese University of Hong Kong

Not yet recruiting

Augmented Velocity Index of Intra-abdominal, Carotid and Retinal Arteries

Arterial Stiffness
Sarepta Therapeutics, Inc.
United States Department of Defense

Completed

Safety Study of Single Administration Post-Exposure Prophylaxis Treatment for Ebola Virus

Ebola Hemorrhagic Fever

United States
Sarepta Therapeutics, Inc.

Terminated

An Exploratory Study of AVI-4020 in Patients With Possible Acute Neuroinvasive West Nile Virus (WNV) Disease

West Nile Fever
Sarepta Therapeutics, Inc.

Completed

Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020

West Nile Virus

United States
Good Food Practice, Sweden

Completed

To Demonstrate That Lactobacillus Reuteri ATCC PTA 4659 Survives Passage Through the Gastrointestinal Tract of Humans

Recovery of Lactobacillus Reuteri ATCC PTA 4659 | The Safety of Lactobacillus Reuteri ATCC PTA 4659

Sweden
Shanghai Changzheng Hospital
First Affiliated Hospital of Zhejiang University; The First Affiliated Hospital... and other collaborators

Unknown

Vascular Access Choice and Outcomes in the Elderly and Very Elderly With End Stage Renal Disease in China (ACCESS-China)

End Stage Renal Disease

China
Ono Pharmaceutical Co. Ltd

Recruiting

Safety, Tolerability, PK, PD and Preliminary Efficacy of ONO-4685

Plaque Psoriasis

United Kingdom, Moldova, Republic of, Romania
Merck Sharp & Dohme LLC

Completed

A Single Dose Study of the Pharmacokinetics of Vibegron (MK-4618) in Participants With Renal Insufficiency (MK-4618-014)

Overactive Bladder
Ono Pharmaceutical Co. Ltd

Recruiting

Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

Relapsed or Refractory T Cell Lymphoma

United States
Sarepta Therapeutics, Inc.

Completed

Pharmacokinetic Study of a Single Dose of AVI-4126 (RESTEN-NG®) in Cerebral Spinal Fluid

Neoplasms

United States
Jazz Pharmaceuticals
Children's Oncology Group (COG)

Completed

An Open-Label Study of JZP-458 (RC-P) in Patients With Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL)

Acute Lymphoblastic Leukemia | Lymphoblastic Leukemia

United States, Canada
Pfizer
Forest Laboratories

Completed

A Study to Assess the Levels of CAZ-AVI and Metronidazole in the Blood When Given Together and Separately

Healthy

United States
Pfizer
Forest Laboratories

Completed

Safety and Tolerability of Ceftazidime-Avibactam for Pediatric Patients With Suspected or Confirmed Infections

Systemic Infections

United States
Centre for Addiction and Mental Health

Completed

Examining a Digital Health Approach for Advancing Schizophrenia Illness Self-management and Provider Engagement

Psychotic Disorders | Schizophrenia | Schizo Affective Disorder

Canada
University of California, Los Angeles
Robert Wood Johnson Foundation

Completed

Randomized Trial of a Social Networks Intervention (AVID)

Adolescent Behavior

United States
AtriCure, Inc.

Completed

aMAZE Trial Continued Access Protocol (aMAZE CAP)

Atrial Fibrillation

United States
Selayang Hospital

Completed

Review of Trend in Incidence and Characteristics of Hospital-acquired Acute Kidney Injury in Hospital Selayang (HA-AKI-HS)

Acute Kidney Injury | Acute Renal Failure | Kidney Failure, Acute | Hospital Acquired Condition

Malaysia
Urovant Sciences GmbH

Completed

Study to Evaluate the Efficacy, Safety and Tolerability of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia (BPH)

Overactive Bladder

United States, Spain, Canada, Portugal, Poland, Belgium, Hungary, Lithuania
Pfizer
Biomedical Advanced Research and Development Authority; Innovative Medicines...

Completed

A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria. (REVISIT)

Ventilator Associated Pneumonia | Complicated Intra-abdominal Infection | Hosptial Acquired Pneumonia

Spain, China, Korea, Republic of, Philippines, United States, Romania, Taiwan, Italy, Malaysia, Mexico, India, Israel, Turkey, Greece, Thailand, Czechia, Croatia, Argentina, Russian Federation, Bulgaria, Ukraine
Abbott Medical Devices

Completed

Substrate and Trigger Ablation for Reduction of Atrial Fibrillation Trial - Star AF II Study (Star AF II)

Atrial Fibrillation

Canada, Australia
Pfizer

Completed

A Phase I Study to Assess the Safety, Tolerability and PK of Ceftazidime-Avibactam in Healthy Chinese Subjects

Healthy Volunteers

China
Sarepta Therapeutics, Inc.
United States Department of Defense

Withdrawn

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers

Ebola Hemorrhagic Fever

United States
Celgene

Completed

Safety and Pharmacokinetics of AVL-292 Following Multiple Doses and the Effect of Food on the Single-dose Pharmacokinetics of AVL-292

Healthy

United States
The Second Affiliated Hospital of Kunming Medical...
First Affiliated Hospital of Kunming Medical University

Recruiting

A New Theory of Electrophysiological Mechanism of Atrial Fibrillation (ANTEMAF)

Atrial Fibrillation

China
Osaka Cardiovascular Conference

Unknown

Efficacy of Pulmonary Vein Isolation Alone in Patients With Persistent Atrial Fibrillation (EARNEST-PVI)

Recurrence | Atrial Fibrillation | Catheter Ablation
Meshalkin Research Institute of Pathology of Circulation

Unknown

Comparison of Redo PVI With vs. Without Renal Denervation for Recurrent AF After Initial PVI

Atrial Fibrillation | Arterial Hypertension

Russian Federation, United States

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