Search clinical trials for: AXS-05 (dextromethorphan-bupropion)

Total 24 results

James Davis
Axsome Therapeutics, Inc.

Completed

AXS-05 Phase II Trial on Smoking Behavior

Smoking Cessation | Nicotine Dependence | Smoking, Cigarette

United States
Axsome Therapeutics, Inc.

Completed

Open-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE)

Major Depressive Disorder | Treatment Resistant Depression

United States
Axsome Therapeutics, Inc.

Completed

Open-Label Safety Study of AXS-05 in Subjects With Depression

Depression | Major Depressive Disorder | Treatment Resistant Depression

United States
Axsome Therapeutics, Inc.

Enrolling by invitation

A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation

Alzheimer Disease | Agitation in Patients With Dementia of the Alzheimer's Type | Agitation, Psychomotor

United States, Canada
Axsome Therapeutics, Inc.

Completed

Mechanistic Evaluation of Response in TRD (MERIT) (MERIT)

Major Depressive Disorder | Treatment Resistant Depression

United States
Axsome Therapeutics, Inc.

Recruiting

A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease Agitation (ADVANCE-2)

Alzheimer Disease | Agitation | Agitation in Patients With Dementia of the Alzheimer's Type

United States, Puerto Rico
Axsome Therapeutics, Inc.

Completed

Assessing Clinical Outcomes in Alzheimer's Disease Agitation (ACCORD)

Alzheimer Disease | Agitation in Patients With Dementia of the Alzheimer's Type | Agitation,Psychomotor

United States, Canada
Axsome Therapeutics, Inc.

Enrolling by invitation

An Evaluation of AXS-05 for the Treatment of TRD in Treatment-Adherent Patients (TARGET)

Major Depressive Disorder | Treatment Resistant Depression

United States
Axsome Therapeutics, Inc.

Completed

A Trial of AXS-05 in Patients With Major Depressive Disorder (GEMINI)

Depression | Major Depressive Disorder

United States
Axsome Therapeutics, Inc.

Completed

A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Treatment Resistant Major Depressive Disorder (STRIDE-1)

Treatment Resistant Major Depressive Disorder

United States
Axsome Therapeutics, Inc.

Completed

Addressing Dementia Via Agitation-Centered Evaluation (ADVANCE)

Alzheimer Disease | Agitation in Patients With Dementia of the Alzheimer's Type | Agitation,Psychomotor

United States, Australia
Axsome Therapeutics, Inc.

Completed

Assessing Symptomatic Clinical Episodes in Depression (ASCEND)

Major Depressive Disorder

United States
Axsome Therapeutics, Inc.

Recruiting

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

Major Depressive Disorder

United States
Children's Mercy Hospital Kansas City
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Developmental Regulation of Proteins Responsible for Transforming Drugs in the Body

Healthy

United States
Centre hospitalier de l'Université de Montréal...
Canadian Institutes of Health Research (CIHR)

Completed

Evaluation of CYP450 Activities in Diabetic Patients vs. Non-diabetic Subjects

Type 2 Diabetes

Canada
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects

Healthy

Belgium
Pfizer
Pierre Fabre Laboratories

Active, not recruiting

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Advanced Solid Tumors | Metastatic Melanoma

United States, Spain, Belgium, Canada, Netherlands
Jules Desmeules

Completed

Cocktail Approach for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spot

Healthy Volunteers

Switzerland
University Hospital, Geneva

Unknown

Drug Metabolism and Antidepressant (METADEP)

Depression

Switzerland
Geha Mental Health Center

Unknown

Comparative Study of SR Bupropion for Adolescent Smoking Cessation

Smoking | Smoking Cessation

Israel
Jules Desmeules

Completed

Evaluation of the Potential Pharmacokinetic Interactions Between Probe Drugs in the Geneva Phenotyping Cocktail

Drug Interaction

Switzerland
Duke University
National Institutes of Health (NIH)

Completed

Treatment of Mood and Marriage Study (TOMMS)

Major Depressive Disorder | Partner Relational Disorder (V61.10)

United States
Abliva AB

Completed

Drug-drug Interaction Study of KL1333 in Healthy Subjects

Mitochondrial Disease

United Kingdom
Shanghai Mental Health Center
First Affiliated Hospital Xi'an Jiaotong University; Chinese Academy of Sciences and other collaborators

Unknown

Multi-Dimensional Diagnosis,Individualized Therapy,and Management Technique for Major Depressive Disorder:Based on Clinical and Pathological Characteristics (STEP-MDD)

Depressive Disorder

China

Search clinical trials for: AXS-05 (dextromethorphan-bupropion)

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