Search clinical trials for: Actilyse

Total 79 results

Universitätsklinikum Hamburg-Eppendorf

Completed

Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke (WAKE-UP)

Stroke

Germany, United Kingdom, Belgium, Denmark, France, Spain
Second Affiliated Hospital, School of Medicine,...

Recruiting

EXtending the Time Window for Thrombolysis in Posterior Circulation Stroke Without Early CT Signs

Stroke, Acute Ischemic

China
Neuroscience Trials Australia
Melbourne Health; University of Melbourne; Commonwealth Scientific and Industrial... and other collaborators

Completed

Extending the Time for Thrombolysis in Emergency Neurological Deficits (EXTEND)

Stroke

Australia, Finland, New Zealand
Joseph Broderick
Medical University of South Carolina; National Institute of Neurological Disorders... and other collaborators

Terminated

Interventional Management of Stroke (IMS) III Trial (IMSIII)

Stroke

Canada, United States, Switzerland, Germany, Spain, Netherlands, Australia, France
Neuroscience Trials Australia
China Medical University Hospital

Completed

EXTEND (International): Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) (EXTEND)

Stroke

Taiwan
South West Sydney Local Health District

Recruiting

Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure (VETtiPAT-ARF)

Acute Respiratory Failure | Hypercoagulability | Fibrinolysis Shutdown

Australia
National Cerebral and Cardiovascular Center
Japan Agency for Medical Research and Development; Charitable Trust Mihara...

Unknown

THrombolysis for Acute Wake-up and Unclear-onset Strokes With Alteplase at 0.6 mg/kg Trial (THAWS) (THAWS)

Stroke

Japan
Berufsgenossenschaftliche Unfallklinik Ludwigshafen

Completed

Synthetic Bone Graft Substitute vs. Autologous Spongiosa in Revision Anterior Cruciate Ligament Reconstruction

Anterior Cruciate Ligament Injury

Germany
The Hospital for Sick Children
Canadian Hemophilia Society

Completed

An Institutional Pilot Study to Investigate Physical Activity Patterns in Boys With Hemophilia (HEPS)

Hemophilia A | Hemophilia B | Factor IX Deficiency | Factor VIII Deficiency

Canada
University Hospital Ostrava
Municipal Hospital Ostrava Fifejdy; Silesian Hospital Opava

Completed

Comparison of Thrombgolytic and Anticoagulation Therapy in Submassive Pulmonary Embolism (CONTACT-SPE)

Pulmonary Embolism

Czechia
Wayne State University

Unknown

Baxter: Actifuse SHAPE vs DBX in ACC

Cervical Spondylosis With Myelopathy | Cervical Spine Degenerative Disease Nos

United States
Baxter Healthcare Corporation
Apatech, Inc.

Completed

Actifuse ABX Versus INFUSE in Posterolateral Instrumented Lumbar Fusion (APPRAISET2)

Degenerative Disc Disease

Australia
Boehringer Ingelheim

Terminated

Protocol for Post Marketing Surveillance of Actilyse Vial

Stroke
Baxter Healthcare Corporation
Apatech, Inc.

Completed

Actifuse ABX Versus INFUSE in Posterolateral Instrumented Lumbar Fusion (PLIF) With Interbody Fusion (APPRAISET1)

Degenerative Disc Disease

Australia, Netherlands
Boehringer Ingelheim

Completed

An International Observational Study of the Safety and Efficacy of Thrombolysis in Stroke

Stroke
Assiut University

Completed

Intracranial Collaterals in Acute Stroke and Clinical Outcome

Collateral Circulation, Any Site

Egypt
Aarhus University Hospital
TRYG Foundation; Danish National Research Foundation; Aase and Ejnar Danielsens...

Completed

New Acute Treatment for Stroke - The Effect of Remote PERconditioning

Acute Stroke

Denmark
Boehringer Ingelheim

Completed

SITS-IVT in Patients >80 Years Study (SITS_ELDERLY)

Ischaemic Stroke

Sweden
Assiut University

Unknown

Anxiety and Depression Disorder in Patient Treated With rTPA for Mangment of Acute Ischemic Stroke

Depression | Anxiety Disorders | Acute Stroke

Egypt
NHS Greater Glasgow and Clyde
National Institute for Health Research, United Kingdom; University of Glasgow

Completed

A Trial of Low-dose Adjunctive alTeplase During prIMary PCI (T-TIME)

Myocardial Infarction

United Kingdom
Boehringer Ingelheim

Completed

Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion

Vascular Access Devices | Catheter Obstruction

Russian Federation
Centre Hospitalier Universitaire de Besancon

Completed

Which Factors Influence the Duration and the Success of Mechanical Thrombectomy During the Acute Phase of Cerebral Infarction? (REPAIR-FC)

Acute Stroke
Boehringer Ingelheim

Terminated

A Study of Pre-hospital Treatment of Acute Myocardial Infarction Based on Diagnosis by Interpretation of Remotely Acquired ECG and Thrombolysis With Accelerated Alteplase ( Actilyse®) (PHARAOH)

Myocardial Infarction
University Hospital Center of Martinique

Withdrawn

Superiority of Rt-PA + Tenecteplase in Comparison With Rt-PA Only in Proximal Middle Cerebral Artery Occlusion (DIVA)

Nervous System Disorders | Cerebral Artery
Vastra Gotaland Region

Recruiting

Optimal Coronary Flow After PCI for Myocardial Infarction - a Pilot Study (OPTIMAL)

ST-segment Elevation Myocardial Infarction

Sweden
Haukeland University Hospital

Terminated

The Norwegian Tenecteplase Stroke Trial 2 (NOR-TEST 2)

Cerebrovascular Disorders | Ischemic Stroke | Stroke, Acute

Norway
Lars Thomassen
The Research Council of Norway

Completed

Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic Stroke (NOR-TEST)

Ischemic Stroke

Norway
Supergene, LLC

Completed

Single Bolus Recombinant Nonimmunogenic Staphylokinase (Fortelyzin) and Bolus Infusion Alteplase in Patients With AIS

Ischemic Stroke

Russian Federation
Seattle Children's Hospital
The Hospital for Sick Children; Medical College of Wisconsin; McMaster University and other collaborators

Terminated

Thrombolysis in Pediatric Stroke (TIPS) (TIPS)

Stroke

United States, Canada
Erasmus Medical Center
DUMAS is sponsored by an unrestricted grant from Thrombolytic Science International...

Completed

Dual Thrombolytic Therapy With Mutant Pro-urokinase and Low Dose Alteplase for Ischemic Stroke (DUMAS)

Ischemic Stroke

Netherlands
Central Hospital, Nancy, France

Terminated

Trial and Cost Effectiveness Evaluation of Intra-arterial Thrombectomy in Acute Ischemic Stroke (THRACE)

Cerebrovascular Accident | Cerebral Stroke

France
University of Florida

Completed

Fibrinolytic Therapy Versus Medical Thoracoscopy

Pleural Diseases

United States
Tomsk National Research Medical Center of the Russian...

Completed

Intramyocardial Haemorrhage in Patients With Primary STEMI (HaemInCor)

Myocardial Infarction | Myocardial Injury | STEMI | Myocardial Necrosis

Russian Federation
Ahi Evren Chest and Cardiovascular Surgery Education...

Unknown

Low Dose Prolonged Infusion of Tissue Type Plasminogen Activator Therapy in Massive Pulmonary Embolism

Pulmonary Embolism

Turkey
Ohio State University
Baxter Healthcare Corporation

Terminated

Comparison of Actifuse ABX and Local Bone in Spinal Surgery

Scoliosis | Kyphosis | Lordosis

United States
University of Cincinnati
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke (CLEAR-ER)

Stroke | Ischemic Stroke | Brain Infarction

United States
Kartal Kosuyolu Yuksek Ihtisas Education and Research...

Completed

Comparison of Different TRansesophageal Echocardiography Guided thrOmbolytic Regimens for prosthetIc vAlve Thrombosis (TROIA)

Prosthetic Valve Thrombosis

Turkey
Tasly Biopharmaceuticals Co., Ltd.

Completed

A Trial in Recombinant Human Prourokinase to Treat Acute Pulmonary Embolism (ERUPTE)

Acute Pulmonary Embolism

China
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy (PE-TRACT)

Pulmonary Embolism

United States
Nantes University Hospital

Completed

A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion (THEIA)

Central Retinal Artery Occlusion

France
NHS Greater Glasgow and Clyde
University of Glasgow

Completed

Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis- (ATTEST) (ATTEST)

Stroke

United Kingdom
Karolinska Institutet
Medtronic - MITG; Swedish Heart Lung Foundation; Phenox GmbH; Stryker Nordic

Completed

SITS (Safe Implementation of Treatments in Stroke) Open Artery by Thrombectomy in Acute Occlusive Stroke Study (SITS Open)

Ischemic Stroke

Sweden
University of Louisville
Genentech, Inc.

Terminated

Safety and Efficacy of Tissue Plasminogen Activator (tPA) in Neonates and Infants

Thrombosis

United States
Johns Hopkins University
Genentech, Inc.

Completed

Safety of Intravenous Thrombolytics in Stroke on Awakening (SAIL-ON)

Stroke

United States
Richard Chang, M.D.
National Institutes of Health Clinical Center (CC)

Completed

Low-Dose Alteplase to Treat Blood Clots in Deep Leg Veins

Acute Deep Venous Thrombosis of the Lower Extremity

United States
Angde Biotech Pharmaceutical Co., Ltd.

Unknown

Injection of Recombinant Human Tissue-type Plasminogen Activator Derivative for Acute Pulmonary Embolism(rPA) (rPA)

Acute Pulmonary Embolism
Kaiser Permanente
Genentech, Inc.

Completed

Alteplase for Percutaneous Treatment of Loculated Abdominopelvic Abscesses

Abdominal Abscess | Pelvic Abscess

United States
Genentech, Inc.

Completed

Cathflo Activase Pediatric Study

Dysfunctional Central Venous Access Devices (CVADS)
Lee Schwamm
National Institute of Neurological Disorders and Stroke (NINDS); Genentech,...

Completed

A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients (MR WITNESS)

Acute Stroke

United States
Midwest Pulmonary and Critical Care
Genentech, Inc.

Completed

Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas (CPE)

Pleural Effusion Associated With Pulmonary Infection | Bacterial Pleural Effusion Other Than Tuberculosis

United States

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