Search clinical trials for: Alogliptin and Metformin hydrochloride

Total 9137 results

Takeda

Completed

Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 Diabetes

Diabetes Mellitus

China, Taiwan, Korea, Republic of, Malaysia
Dong-A ST Co., Ltd.

Unknown

Observational Study to Evaluate the Efficacy and Safety of Suganon Tab. or Sugamet XR Tab.

Diabetes Mellitus, Type 2

Korea, Republic of
Takeda

Completed

Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"

Type 2 Diabetes Mellitus

Japan
Takeda

Completed

Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Australia, Brazil, Chile, Guatemala, India, Mexico, New Zealand, Peru, South Africa, Czech Republic, Germany, Hungary, Netherlands, Poland, United Kingdom, Argentina
Takeda

Completed

Comparative Study to Evaluate Efficacy and Safety When Metformin Hydrochloride 500 mg Once Daily is Added on to SYR-322 25 mg in Type 2 Diabetic Patients With Inadequate Glycemic Control Despite Treatment With SYR-322 25 mg in Addition to Diet and Exercise Therapy

Type 2 Diabetes Mellitus

Japan
Dong-A ST Co., Ltd.

Completed

A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01(Evogliptin/Metformin XR 2.5/500 mg x 2 Tablets) Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg in Healthy Male Volunteers

Type 2 Diabetes Mellitus

Korea, Republic of
Takeda

Terminated

Non-Interventional Study of the Use of Alogliptin and Alogliptin Fixed-Dose Combinations With Pioglitazone and With Metformin in Standard Clinical Practice

Diabetes Mellitus, Type 2

China, Hong Kong
Dong-A ST Co., Ltd.

Completed

A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01 Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg, and to Evaluate the Effect of Food on the Pharmacokinetics of DA-1229_01 in Healthy Male Volunteers

Type 2 Diabetes Mellitus

Korea, Republic of
Takeda

Completed

Long-term Safety Study of Alogliptin Used in Combination With Sulfonylurea or Metformin in Participants With Type 2 Diabetes in Japan

Type 2 Diabetes Mellitus
Institute for Clinical and Experimental Medicine

Completed

Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes (CARMET)

Insulin Resistance | Chronic Heart Failure

Czechia
Fourth People's Hospital of Shenyang

Completed

The Effect of Alogliptin on Pulmonary Function in Obese Patients With Type 2 Diabetes Inadequately Controlled by Metformin Monotherapy

Diabetes Mellitus, Type 2
University of Catanzaro

Unknown

Anti-inflammatory Status in DM2 Treated Patients (INF-DM2-Ther)

Diabetes Mellitus, Type 2

Italy
Takeda

Completed

Efficacy and Safety of Alogliptin Used Combination With Metformin in Participants With Type 2 Diabetes in Japan

Type 2 Diabetes Mellitus
Haisco Pharmaceutical Group Co., Ltd.
The Fourth Hospital of Hebei Medical University

Recruiting

A Study Evaluating Drug-Drug Interaction (DDI) Between HSK16149 Capsules and Metformin Hydrochloride Tablets

Diabetic Neuropathies | Diabetic Neuropathy Peripheral

China
Takeda

Completed

Phase 1 Bioavailability Study of SYR-322MET

Healthy Volunteers
University of Utah
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Recruiting

Metformin for Fibromyalgia Symptoms (INFORM Trial)

Fibromyalgia Syndrome

United States
Dong-A ST Co., Ltd.

Completed

Efficacy and Safety of Evogliptin When Added to Ongoing Metformin and Dapagliflozin Combination Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control

Type2 Diabetes

Korea, Republic of
GC Biopharma Corp

Recruiting

A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fasting Conditions

Healthy Volunteers

Korea, Republic of
Dong-A ST Co., Ltd.

Unknown

A Clinical Trial to Evaluate the Preference Regarding Convenience of Medication and Efficacy/Safety of SUGAMET®XR Tablet 5/1000mg

Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | Metabolic Disease | Renal Disease

Korea, Republic of
Celltrion

Completed

A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 25 mg and MET XR 1,000 mg) in Healthy Volunteers

Healthy

Korea, Republic of
University of Arizona
National Cancer Institute (NCI)

Recruiting

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Oral Leukoplakia | Erythroplakia

United States, Canada
National Cancer Institute (NCI)

Recruiting

Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer

Lung Carcinoma

United States, Canada
GC Biopharma Corp

Recruiting

A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fed Conditions

Healthy Volunteers

Korea, Republic of
GlaxoSmithKline

Completed

Evaluation of Food Effect on the Pharmacokinetics of Sustained Release Metformin in Healthy Indian Volunteers

Diabetes Mellitus, Type 2
Celltrion

Completed

A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 12.5 mg and MET XR 500 mg) in Healthy Volunteers

Healthy

Korea, Republic of
UConn Health

Completed

Vaccination Efficacy With Metformin in Older Adults (VEME)

Aging | Vaccine Response Impaired | Age-Related Immunodeficiency

United States
Bing He

Active, not recruiting

Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.

Polycystic Ovary Syndrome

China
Dong-A ST Co., Ltd.

Completed

Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of Evogliptin 5 mg and Pioglitazone 30 mg

Type 2 Diabetes

Korea, Republic of
RenJi Hospital

Completed

The Effect of Metformin on Reducing Lupus Flares (Met Lupus)

Systemic Lupus Erythematosus

China
Laboratorios Silanes S.A. de C.V.

Completed

Metformin Glycinate on Metabolic Control and Inflammatory Mediators in Type 2 Diabetes (COMET)

Type 2 Diabetes

Mexico
Johns Hopkins University
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Temple University

Not yet recruiting

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Asthma | Overweight and Obesity | Asthma Chronic
Torrent Pharmaceuticals Limited

Completed

Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fasting Conditions

Healthy

India
Brian Zuckerbraun

Completed

Effects of Metformin in a Non-Diabetic Patient Population

Inflammatory Response

United States
Takeda

Completed

Efficacy and Safety of Alogliptin Plus Metformin in Patients With Type 2 Diabetes (AM7D)

Diabetes Mellitus, Type 2

United States, Ukraine, Israel, Mexico, Romania, Russian Federation, South Africa, Czech Republic, Puerto Rico, Poland, Hungary, Lithuania, Slovakia
Zagazig University

Completed

Insulin Sensitizers Role in Control of PCOS Vicious Cycle.

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Egypt
Columbia University
Breast Cancer Research Foundation

Completed

Pre-Surgical Study: Effect of Metformin on Breast Cancer Proliferation

Breast Cancer

United States
The Hospital for Sick Children
University of Alberta; University of Waterloo

Terminated

Metformin Treatment in Infants After Perinatal Brain Injury

Premature Birth | Hypoxic Ischemic Encephalopathy of Newborn

Canada
NHS Tayside
University of Southern Denmark; Helmholtz Zentrum München; University of Dundee

Completed

Pharmacokinetics of Metformin Intolerance (POMI)

Diabetes Mellitus, Type 2 | Metformin Adverse Reaction
Torrent Pharmaceuticals Limited

Completed

Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fed Conditions

Healthy

India
National Eye Institute (NEI)

Recruiting

Oral Metformin for Treatment of ABCA4 Retinopathy

Retinal Degeneration | Stargardt Disease | ABCA4 Retinopathy | Retinal Dystrophy

United States
Anna Stanhewicz, PhD

Not yet recruiting

Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

Gestational Diabetes
University of Kansas Medical Center

Recruiting

Effects of Metformin on Airway Ion Channel Dysfunction in Cystic Fibrosis-related Diabetes

Cystic Fibrosis | Cystic Fibrosis-related Diabetes

United States
University of California, Davis
National Cancer Institute (NCI); Astellas Pharma Inc; Medivation, Inc.

Active, not recruiting

Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer

Prostate Cancer

United States
Columbia University

Recruiting

Metformin in Heart Failure Without Diabetes (Met-HeFT)

Heart Failure

United States
Canadian Cancer Trials Group
National Cancer Institute (NCI); ETOP IBCSG Partners Foundation; ICR-CTSU

Completed

A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer

Breast Cancer

United States, Canada, Switzerland, United Kingdom
Shenzhen People's Hospital

Unknown

Effect of Metformin as add-on Therapy on Glycemic Control and Other Outcomes in Type 1 Diabetes

Type 1 Diabetes Mellitus | Metformin

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Metformin and Nightly Fasting in Women With Early Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Breast Ductal Carcinoma In Situ | Invasive Breast Carcinoma

United States, Italy
Laboratorios Silanes S.A. de C.V.

Suspended

Efficacy and Safety of Metformin Glycinate Compared to Metformin Hydrochloride on the Progression of Type 2 Diabetes (COMETII)

Type 2 Diabetes

Mexico
Medical University of Bialystok
Medical Research Agency, Poland

Not yet recruiting

Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility (METIN)

Infertility, Female
National University of Ireland, Galway, Ireland
Health Research Board, Ireland; University Hospital of Limerick; University College... and other collaborators

Completed

A Randomized Placebo Controlled Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects (EMERGE)

Gestational Diabetes

Ireland

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