Search clinical trials for: Alpha-Glucosidase Inhibitors (α-GI)

Total 2860 results

Genzyme, a Sanofi Company

Approved for marketing

Alglucosidase Alfa Temporary Access Program (ATAP)

Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2 | Pompe Disease (Late-Onset)

United States
Genzyme, a Sanofi Company

Completed

Safety and Efficacy of Recombinant Human Acid Alpha-Glucosidase in the Treatment of Classical Infantile Pompe Disease

Glycogen Storage Disease Type II | Acid Maltase Deficiency Disease | Glycogenosis 2 | Pompe Disease

United States
Mitchell Cairo

Recruiting

AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion

Hodgkin Lymphoma | Sickle Cell Disease | Acute Leukemia | Beta-Thalassemia | Non-hodgkin Lymphoma | Severe Aplastic Anemia | Diamond Blackfan Anemia | Amegakaryocytic Thrombocytopenia | Kostmann

United States
Amicus Therapeutics

Completed

Drug-drug Interaction Study

Pompe Disease

France, United States, Canada, United Kingdom
Eli Lilly and Company

Completed

A Study of LY2189265 in Japanese Participants With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Japan
Digna Biotech S.L.

Completed

A Phase I/II Clinical Trial With Interferon Alfa 5 in Treatment-Experienced Patients With Genotype-1 Chronic Hepatitis C

Chronic Hepatitis C Virus Infection | Genotype 1 | Treatment-Experienced Patients | Relapses

Spain
University of Campinas, Brazil

Completed

Effects of the TNF-alpha Inhibiton on Hemodynamic Parameters in Resistant Hypertension

Hypertension

Brazil
Shanghai Jiao Tong University School of Medicine

Unknown

Experimental Trial of rhIFNα Nasal Drops to Prevent 2019-nCOV in Medical Staff

2019 Novel Coronavirus Infection

China
BioGeneric Pharma
Xiamen Amoytop Biotech Co., Ltd.

Unknown

Y- Shaped Pegylated Interferon (YPEG-IFNα-2a) Plus Ribavirin in Egyptian Patients With Untreated Chronic Hepatitis C

Hepatitis C | Self Efficacy

Egypt
Mackay Memorial Hospital

Completed

Left Ventricular Functional Changes of Uncontrolled Diabetes by Dapagliflozin Treatment Trial (ELUCIDATE)

Type 2 Diabetes Mellitus

Taiwan
Mitsubishi Tanabe Pharma Corporation

Completed

Long-term Safety Study of MP-513 in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

Japan
Third Military Medical University

Completed

Liraglutide Improve Cognitive Function in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

China
Eli Lilly and Company

Completed

A Study Comparing Insulin Peglispro With Insulin Glargine as Basal Insulin Treatment

Type 2 Diabetes Mellitus

Japan, Taiwan, Korea, Republic of
Lee's Pharmaceutical Limited

Not yet recruiting

Non-inferiority Study of ZK-A03 in Treatment of Herpes Zoster Before and After the Alteration of the Active Ingredient Manufacturer

Herpes Zoster
Grifols Therapeutics LLC

Completed

Safety and Tolerability Trial of Inhaled Alpha1-Proteinase Inhibitor (Human), Hydrophobic Chromatography Process (Alpha-1 HC) in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States
Astellas Pharma Inc

Completed

A Study to Assess the Safety and Efficacy of ASP1941 in Combination With α-glucosidase Inhibitor in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Japan
Grifols Therapeutics LLC

Terminated

Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
Grifols Therapeutics LLC

Completed

Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency (SPARK)

Emphysema | Alpha 1-antitrypsin Deficiency (AATD)

United States
Hanyang University
Roche Pharma AG

Unknown

Efficacy Study of Sequential Therapy of Peginterferon Alfa-2a Following Entecavir in Patient With Chronic Hepatitis B. (POTENT)

Hepatitis B, Chronic

Korea, Republic of
Emory University
Bayer

Completed

Immunotherapy for Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Blast Phase Chronic Myelogenous Leukemia (BP CML), and Myelodysplastic Syndrome (MDS) Relapse After Allogeneic Transplantation

Leukemia

United States
Kenneth Madden

Completed

Acarbose and Older Adults With Postprandial Hypotension (PPH)

Syncope | Other Specified Hypotension

Canada
New Mexico Cancer Care Alliance

Terminated

Biomarker Study of Neoadjuvant Vitamin E in Patients With Locally Treatable Prostate Cancer

Prostate Cancer

United States
University of Miami

Recruiting

Belinostat Therapy With Zidovudine for Adult T-Cell Leukemia-Lymphoma

Adult T-cell Leukemia-Lymphoma | ATLL

United States
Necmettin Erbakan University

Completed

Evaluation of the Effect of Periimplant Soft Tissue Phenotype on Marginal Bone Loss

Dental Implant | Alveolar Bone Loss | Periimplantitis

Turkey
Abramson Cancer Center of the University of Pennsylvania

Completed

IFN-DLI for Relapsed Acute Leukemia After Allo-SCT

Leukemia

United States
Peking University People's Hospital

Unknown

Interferon α for the Therapy of Minimal Residual Disease

Leukemia

China
Grifols Therapeutics LLC

Terminated

Study to Evaluate the Safety and Efficacy of Liquid Alpha1-Proteinase Inhibitor (Human) in Hospitalized Participants With Coronavirus Disease (COVID-19)

COVID-19

United States, Brazil, Chile, Colombia, Mexico
Sanofi

Completed

Safety and Tolerability of Lixisenatide in Combination With Oral Anti-Diabetic Treatment in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

Japan
Nanjing First Hospital, Nanjing Medical University

Completed

Epidural Intervention of Spinal Nerves With Tumor Necrosis Factor-Alpha Inhibitor

Spinal Stenosis
GI Innovation, Inc.
Merck Sharp & Dohme LLC

Recruiting

GI-101 as a Single Agent or in Combination With Pembrolizumab, Lenvatinib or Local Radiotherapy in Advanced Solid Tumors

Melanoma | Sarcoma | Renal Cell Carcinoma | Cervical Cancer | Urinary Bladder Cancer | Vulvar Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Vaginal Cancer | Microsatellite Stable...

Korea, Republic of, United States
Huashan Hospital

Not yet recruiting

Functional Cure Rate of Peg-IFNα-2b Combined With TAF in HBeAg Negative CHB Patients

Chronic Hepatitis B
Peking University People's Hospital

Unknown

Interferon-α After DLI for the Prevention of Relapse (IDPR-HSCT)

Leukemia

China
Ohio State University Comprehensive Cancer Center

Completed

Study of Patients With Stage IV Malignant Melanoma Using PS-341 (Bortezomib, Velcade) and Interferon-alpha-2b in Malignant Melanoma

Melanoma

United States
Shire

Withdrawn

ARALAST NP Alpha-1 Lung Density Chronic Obstructive Pulmonary Disease-Emphysema (COPD-E) Study

Chronic Obstructive Pulmonary Disease | Alpha1-antitrypsin Deficiency
University Health Network, Toronto
Princess Margaret Hospital, Canada

Terminated

The Use of Pentoxifylline and Vitamin E in the Treatment of Late Radiation Related Injuries

Wounds and Injuries

Canada
Grifols Therapeutics LLC

Recruiting

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency

Alpha1-Antitrypsin Deficiency

United States
Takeda

Withdrawn

A Study of RYMPHYSIA for Alpha1-Proteinase Inhibitor (A1PI) Therapy in Adults With A1PI Deficiency and Chronic Obstructive Pulmonary Disease (COPD)-Emphysema

Chronic Obstructive Pulmonary Disease (COPD) | Alpha1-Antitrypsin Deficiency
Baxalta now part of Shire
Baxter Healthcare, Ltd. (New Zealand), Baxter Healthcare Pty. Ltd. (Australia)

Completed

Pharmacokinetic Study of ARALAST (Human Alpha1- PI)

Alpha 1-Antitrypsin Deficiency

Australia, New Zealand
Yale University
Celgene; Kyowa Kirin Co., Ltd.

Completed

Combination of Lenalidomide and Autologous Mature Dendritic Cells Pulsed With KRN7000 in Myeloma

Myeloma

United States
Northwestern University
National Cancer Institute (NCI)

Terminated

Study of Pegylated Interferon-Alfa 2b in Combination With PUVA Therapy In CTCL

Lymphoma

United States
OncoCareClinic 308 Ltd

Recruiting

The 1st Tumor CytokinoTherapy Database (TCTD-1)

Oncology

Russian Federation
CSL Behring

Completed

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

Emphysema | Alpha1-proteinase Inhibitor Deficiency

Australia, Russian Federation, United States, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden, Canada, Czech Republic
Baxalta now part of Shire

Completed

GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study

Alpha1-antitrypsin Deficiency

United States, Canada
Baxalta now part of Shire

Terminated

Aralast alpha1-proteinase Inhibitor Surveillance Study

Alpha1-antitrypsin Deficiency

United States
GlaxoSmithKline

Completed

A Study to Determine the Long Term Safety and Efficacy of Albiglutide in Combination With Oral Monotherapy Antihyperglycemic Medications in Japanese Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus

Japan
Kamada, Ltd.

Completed

Phase II Study to Evaluate the Efficacy and Safety of Glassia® in Type-1 Diabetes

New Onset Type-1 Diabetes

Israel
Sanofi

Completed

A Study to Evaluate the Effectiveness and Safety Initiation and Titration of Insulin Glargine (U300) in Insulin-naïve Patients With Type 2 Diabetes Mellitus (T2DM) Controlled on Oral Antidiabetic Drug Treatment in Turkey (EASE)

Type 2 Diabetes Mellitus

Turkey
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI); NCIC Clinical Trials Group; Children's Oncology... and other collaborators

Active, not recruiting

High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III Melanoma

Melanoma (Skin)

United States, Canada, Australia, South Africa
Baxalta now part of Shire

Completed

Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Proteinase Inhibitor)

Alpha 1-Antitrypsin Deficiency

New Zealand, Australia
University of Dundee

Recruiting

Bronchiectasis Alpha-1 Augmentation Trial- Modulating Airway Neutrophil Function (BATMAN)

Bronchiectasis Adult

United Kingdom

Search clinical trials for: Alpha-Glucosidase Inhibitors (α-GI)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Finland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations