Search clinical trials for: Antagonist

Total 32734 results

Tracon Pharmaceuticals Inc.
Janssen Pharmaceutica N.V., Belgium

Completed

Phase 1/2A Study of TRC253, an Androgen Receptor Antagonist, in Metastatic Castration-resistant Prostate Cancer Patients

Metastatic Castrate-resistant Prostate Cancer | Adenocarcinoma, Prostate

United States
Bristol-Myers Squibb

Completed

A Phase I Dose-Escalation Study of BMS-641988 in Patients With Castration-Resistant Prostate Cancer

Prostate Cancer

United States
Center for Clinical Pharmacology Research Bdbeq...
Laboratorio Elea Phoenix S.A.

Unknown

Single Dose Bioequivalence Study of Darifenacin Tablets 7.5 mg in Fed Healthy Volunteers.

Bioequivalency

Uruguay
Suzhou Kintor Pharmaceutical Inc,

Completed

The Safety and Tolerability of GT0918 in Subjects With mHSPC and mCRPC

Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) | Metastatic Castrate Resistant Prostate Cancer (mCRPC)

United States
Suzhou Kintor Pharmaceutical Inc,

Completed

Safety, Tolerability, and PK of GT0918 (Proxalutamide) in Subjects With Metastatic Castrate Prostate Cancer

Metastatic Castrate Resistant Prostate Cancer (mCRPC)

United States
King Abdullah International Medical Research Center

Recruiting

The Efficacy of Leukotriene Inhibitor in Adult Patients With Moderate SARS-COV-2 Symptoms (COVID19) (PROMISE)

Moderate Covid19

Saudi Arabia
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Aldosterone Antagonist Therapy for Adults With Heart Failure and Preserved Systolic Function (TOPCAT)

Heart Diseases | Cardiovascular Diseases | Heart Failure, Congestive

United States, Canada, Brazil, Argentina, Georgia, Russian Federation
National Institute of Diabetes and Digestive and...
American Diabetes Association

Completed

Effect of Varying Testosterone Levels on Insulin Sensitivity in Normal and IHH Men

Hypogonadism

United States
University Ghent
Research Foundation Flanders

Completed

Influence of Endurance Exercise and Histamine Receptors on the Gene Expression in Skeletal Muscle

Exercise | Histamine

Belgium
GlaxoSmithKline

Completed

SUrvey of Guideline Adherence for Treatment of Systolic Heart Failure in Real World (SUGAR)

Heart Failure, Congestive

Korea, Republic of
Actelion

Withdrawn

Correlation of LONGterm Wrist ACTigraphy Recorded Physical Performance & 6-minute Walk Distance in Patients With Pulmonary Arterial Hypertension (LONGACT)

Pulmonary Arterial Hypertension
KBP Biosciences

Completed

Safety, Tolerability and Pharmacokinetics of KBP-5074 in Healthy Subjects and Subjects With Renal Impairment

Healthy | Renal Insufficiency

United States
Fayoum University

Not yet recruiting

Progesterone Primed Ovarian Stimulation Protocol Versus Antagonist Protocol for PCO Patient

Polycystic Ovary Syndrome | Infertility | IVF
The George Institute

Not yet recruiting

The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect (CAPTIVATE)

Chronic Kidney Diseases
Imperial College London
Dr Katrina Ohla, Institute of Neuroscience and Medicine, Julich, Germany

Unknown

Investigating Salt Taste Threshold in Patients Being Investigated for Primary Hyperaldosteronism Before and After Treatment. (AldoSalt)

Hypertension | Hyperaldosteronism; Primary | Salt; Excess | Appetite Disorders

United Kingdom
Ajjai Alva, MD
Hoosier Cancer Research Network; Bayer Healthcare Pharmaceuticals, Inc./Bayer...

Terminated

Androgen Deprivation Therapy +/- Radium-223 Dichloride in Metastatic Prostate Cancer With Bone Metastases

Prostate Cancer | Bone Metastases | Prostate Neoplasms

United States
Bayer

Completed

A Study Using Surveys to Learn More About Treatment With Steroidal Mineralocorticoid Receptor Antagonists, How They Are Used, What Side Effects They Have, and How Satisfied People Who Receive Them Are in the US

Heart Failure | Type 2 Diabetes Mellitus | Chronic Kidney Disease

United States
Institute for Human Reproduction (IHR)

Completed

GnRH Antagonist to Prepare Recipients for Embryo Transfer

Infertility

United States
Hvidovre University Hospital

Completed

Incretin Hormone Antagonism After Bariatric Surgery (INCA-BAR)

Bariatric Surgery

Denmark
ShangHai Ji Ai Genetics & IVF Institute

Not yet recruiting

Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Women With PCOS Undergoing PGT-A

GnRH Antagonist | Polycystic Ovarian Syndrome | Preimplantation Genetic Testing | Progestin-primed Ovarian Stimulation
ClinAmygate
Cairo University; Al-Azhar University; Beni-Suef University

Completed

Coasting Versus Antagonist Protocol in Patients at High Risk of OHSS

Ovarian Hyperstimulation Syndrome

Egypt
ShangHai Ji Ai Genetics & IVF Institute

Completed

Effect of GH Supplementation on the Blastocyst Euploid Rate in AMA Patients--A Retrospective Cohort Study

Growth Hormone | Advanced Maternal Age | PGT-A

China
Riyadh Fertility and Reproductive Health center

Unknown

Growth Hormone Co-treatment Within a GnRH Antagonist Protocol in Patients With Poor Ovarian Response

Infertility, Female

Egypt
Washington University School of Medicine
University of Pennsylvania

Withdrawn

CLCNKA (Ka Renal Chloride Channel[ClC-Ka]) Polymorphism Effects on Hypertrophy Regression

Hypertension

United States
KBP Biosciences

Completed

Safety, Tolerability, and Pharmacokinetics of KBP-5074 Following Oral Administration in Chronic Kidney Disease

Chronic Kidney Disease

United States
Brigham and Women's Hospital

Recruiting

Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

Hypertension | Primary Aldosteronism

United States
University of Colorado, Denver

Completed

Effects of Testosterone and Fat Utilization

Healthy | Volunteers
Biogen

Terminated

Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency (POSEIDON)

Heart Failure | Renal Insufficiency

United States
Assiut University

Unknown

Impact of Gonadotrophin Releasing Hormone Analogues on Oocyte and Embryo Quality

Infertility, Female
Shanghai First Maternity and Infant Hospital

Unknown

A Randomized Double Blind Comparison of Atosiban in Patients With RIF Undergoing IVF Treatment

Repeated Implantation Failure
University College, London
British Heart Foundation

Completed

Early Mineralocorticoid Receptor Antagonist Treatment to Reduce Myocardial Infarct Size (MINIMISE-STEMI)

ST-elevation Myocardial Infarction

United Kingdom
Children's Hospital of Fudan University

Completed

Experienced Chinese Herbal Formulas on Pediatric Asthma

Childhood Asthma

China
Eugonia

Unknown

Luteal Antagonist Versus Conventional Treatment in Women With Severe Early Ovarian Hyperstimulation Syndrome (OHSS)

Ovarian Hyperstimulation Syndrome

Greece
Turku University Hospital

Unknown

The Effect of ADT on PSMA-PET. (ADTPSMA)

Prostate Cancer

Finland
Vanderbilt University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Brigham...

Completed

Glucose Metabolism in Subjects With Aldosterone-Producing Adenomas

Primary Aldosteronism

United States
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

GnRH Antagonist for Treatment of Early Ovarian Hyperstimulation Syndrome

Ovarian Hyperstimulation Syndrome | Effects of Gonadotropin | Oocyte Maturation

Spain
Hywel Dda Health Board
Swansea University

Completed

sTep dOWn Inhalers in the reAl woRlD (TOWARD)

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Colorado, Denver

Completed

Dysregulation of FSH in Obesity: Functional and Statistical Analysis

Obesity | Fertility

United States
Massachusetts General Hospital
National Institutes of Health (NIH)

Unknown

Letrozole Treatment in Normal and GnRH Deficient Women

Healthy Volunteers

United States
Ocuphire Pharma, Inc.
Viatris Inc.

Recruiting

Safety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual Disturbances (LYNX-2)

Mesopic Vision | Night Vision Loss

United States
ShangHai Ji Ai Genetics & IVF Institute

Recruiting

Effect of GH on the Blastocyst Euploid Rate in AMA Patients

Preimplantation Genetic Testing | Growth Hormone | Age, Parental

China
New Valley University

Completed

Progesterone Primed Endometrial Protocol Versus Gonadotropin-releasing Hormone Antagonist Protocol in Assisted Reproductive Treatments

Progesterone Primed Endometrial Protocol | Gonadotropin Releasing Hormone Antagonist Protocol | Assisted Reproductive Treatments

Egypt
Johns Hopkins University
Fast Grants

Terminated

Prazosin to Prevent COVID-19 (PREVENT-COVID Trial) (PREVENT)

COVID-19

United States
Centre for Endocrinology and Reproductive Medicine...

Completed

Use of Degarelix in Controlled Ovarian Hyperstimulation (COH) Protocol for Women With PoliCystic Ovarian Syndrome (PCOS)

PCOS | INFERTILITY | OHSS

Italy
University Hospital Schleswig-Holstein

Completed

Ovarian Response Prediction in In Vitro Fertilization (IVF) Patients

Infertility, Subfertility

Norway, Germany
Yale University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Mechanisms of Hypertension in Women With Polycystic Ovary Syndrome

Hypertension | Polycystic Ovary Syndrome

United States
ShangHai Ji Ai Genetics & IVF Institute

Recruiting

Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Patients Undergoing PGT-A

GnRH Antagonist | Preimplantation Genetic Testing | Progestin-primed Ovarian Stimulation | Euploid Rate

China
Centro Ginecologia y Obstetricia.
University of Valencia

Completed

Administration of GnRH Antagonist to Oocyte Donation Recipients (GnRH-Ovodon)

Pregnancy | Embryo Implantation

Spain
Medical University of South Carolina
University of South Carolina

Completed

Controlling Blood Pressure in Treatment Resistant Hypertension: A Pilot Study (TRH)

Hypertension

United States
Xuzhou Medical University

Unknown

the Effect of Tracleer on Tourniquet-associated Hypertension

Hypertension | Tourniquets | Bosentan

China

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