Search clinical trials for: Antidepressive Agents, Second-Generation

Total 5392 results

The Hospital for Sick Children

Completed

Metabolic Availability of Tryptophan From White Maize

Healthy

Canada
Queen's University

Completed

Double Blind Study of Trp01 in Patients With Alzheimer's Disease

Alzheimer's Disease

Canada
The Hospital for Sick Children
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

The Tryptophan Requirement in Healthy Adults

Healthy Aging
Indiana University

Recruiting

5HTP Regulation Of Asthma In Children

Mild or Moderate Asthma With Allergic Sensitization

United States
University of Maryland, Baltimore
National Institute of Mental Health (NIMH); Mitsubishi Tanabe Pharma Corporation

Completed

Tryptophan MRI in People With Schizophrenia and Healthy Controls

Schizophrenia

United States
University Hospital, Clermont-Ferrand

Unknown

Effect of the Quality of Dietary Proteins on the Sleep Young Elite Athletes and the Obese Adolescent (Protmorpheus)

Obese Adolescent | Elite Adolescent Athletes

France
PepsiCo Global R&D

Completed

Nutrients to Enhance Sleep Quality and Quantity

Sleepiness in Athletes
The Hospital for Sick Children

Completed

Tryptophan Requirement of Healthy School Age Children

Healthy

Canada
University of Groningen

Completed

Serotonin and Everyday Social Interaction

Social Behaviour
Northumbria University

Completed

Sub-chronic Effects of 5-hydroxytryptophan on Mood and Emotional Processing in Healthy Volunteers

Mood

United Kingdom
University of Groningen

Completed

Mood, Serotonin and Social Interaction

Mood | Social Behavior

Netherlands
McMaster University
Canadian Institutes of Health Research (CIHR); National Research Agency, France

Completed

The Role of Dietary Tryptophan on Aryl Hydrocarbon Receptor Activation (Aryl-IMMUNE)

Diet Modification

Canada
TNO
Laboratoire Oenobiol

Completed

The Effect of 5-Hydroxytryptophan (5-HTP) on Satiety

Obesity

Netherlands
Qilu Hospital of Shandong University

Recruiting

Tryptophan Metabolites in Pediatric Migraine

Migraine in Children

China
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Completed

Exploring the Mechanisms of Indoxyl Sulfate Production by Oral Tryptophan Challenge Test

Healthy | Chronic Kidney Diseases

Taiwan
Rambam Health Care Campus
Beersheva Mental Health Center

Completed

Tryptophan Depletion in Acute Mania

Bipolar Disorder

Israel
Fundació Sant Joan de Déu
Instituto de Salud Carlos III

Completed

A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity

Obesity
KU Leuven

Recruiting

A Nutritional Intervention to Prevent Stress Induced Intestinal Hyper-Permeability (HYPERNUTRI)

Stress, Psychological

Belgium
National University, Singapore

Completed

Impact of Nutritional Supplementation on Sleep Quality and Gut Microbiome Composition in Older Adults

Sleep | Gut Microbiome

Singapore
Assiut University

Unknown

Anaesthesia and Tryptophan Pathway

Tryptophan Pathway

Egypt
National Institute on Drug Abuse (NIDA)
Johns Hopkins University

Completed

Tryptophan and Behavior Therapy for Cocaine Abuse - 1

Cocaine-Related Disorders

United States
Universitaire Ziekenhuizen KU Leuven

Completed

The Effect of Acute Tryptophan Depletion (ATD) on Esophageal Sensitivity in Healthy Volunteers

Esophageal Sensitivity

Belgium
Perry Renshaw

Completed

5-hydroxytryptophan and Creatine for Treatment Resistant Depression Associated With Hypoxia in Females

Major Depressive Disorder

United States
Indiana University School of Medicine

Completed

The Role of Serotonin in Hot Flashes After Breast Cancer

Breast Cancer

United States
NewLink Genetics Corporation

Completed

Oral Bioavailability,and Food Effect Study and Single Ascending Dose PK Study in Healthy Male Volunteers

Healthy

Canada
NewLink Genetics Corporation

Completed

Single Ascending Dose PK, Oral Bioavailability and Food Effect Study in Healthy Male Volunteers (NLG2111)

Healthy

United States
Brent Michael Kious, MD, PhD

Terminated

Placebo-controlled Trial of 5-hydroxytryptophan and Creatine for SSRI or SNRI Augmentation in Treatment Resistant Depression in Females

Major Depressive Disorder

United States
Masonic Cancer Center, University of Minnesota

Completed

Phase II Study of Sipuleucel-T and Indoximod for Patients With Refractory Metastatic Prostate Cancer

Metastatic Prostate Cancer

United States
Fundación EPIC

Recruiting

Evaluation of the Safety and Efficacy of Titanium-nitric Oxide-coated Stent (Optimax®) in Patients With Lesions With a Low Risk of Restenosis (Diameter ≥ 3.0 mm and Length ≤ 20 mm) (RETO 320)

Coronary Artery Disease

Spain
Valenta Pharm JSC

Completed

A Study of the Efficacy and Safety of Ranquilon Tablets in Patients With Anxiety in Neurasthenia and Adjustment Disorders

Anxiety | Adjustment Disorders | Neurasthenia

Russian Federation
Maastricht University Medical Center
Netherlands Brain Foundation

Terminated

Tryptophan Depletion in PD Patients Treated With STN DBS

Parkinson's Disease

Netherlands
NewLink Genetics Corporation

Terminated

IDO Inhibitor Study for Relapsed or Refractory Solid Tumors (D-1MT)

Melanoma | Breast Cancer | Pancreatic Cancer | Lung Cancer | Solid Tumors

United States
National Cancer Institute (NCI)

Completed

1-Methyl-D-Tryptophan in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific

United States
Barbara Ann Karmanos Cancer Institute
Washington University School of Medicine

Recruiting

F-Tryptophan PET/CT in Human Cancers

Breast Cancer | Rectal Cancer | Neuroendocrine Tumors | Metastatic Brain Tumor | Intracranial Glioma

United States
National Yang Ming University

Completed

Tryptophan Supplementation to Improve Night Shift Workers' Health

Burnout | Sleep | Mood | Melatonin Deficiency | Cortisol Deficiency

Taiwan
HCA Healthcare Research Institute
Balt USA

Recruiting

Optima Coil Performance in The Interventional Management of Intracranial Aneurysms Registry (OPTIMA)

Intracranial Aneurysm

United States
Massachusetts General Hospital

Completed

Dietary Intake of Tryptophan and Metformin Response

Fasting Glucose | Metformin Response | Tryptophan Concentration | Metformin Concentration | Diet Tolerability

United States
John D. Dingell VA Medical Center

Withdrawn

Pilot Study: Combining Nutritional Supplements With Standard Antidepressant to Treat Depression.

Depression

United States
National Cardiovascular Center Harapan Kita Hospital...

Unknown

Role of Terminal Warm Blood Cardioplegia as Myocardial Protection in the Use of Histidine-Tryptophan-Ketoglutarate Cardioplegia in Complex Congenital Heart Surgery

Congenital Heart Disease

Indonesia
Seattle Children's Hospital

Recruiting

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Soft Tissue Sarcoma | Carcinoma | Osteosarcoma | Ewing Sarcoma | Rhabdoid Tumor | Neuroblastoma | Retinoblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Synovial Sarcoma | Desmoplastic Small Round Cell Tumor | Germ Cell Tumor | Pediatric Solid Tumor | Clear Cell Sarcoma | Malignant Peripheral Nerve Sheath Tumors

United States
Changhai Hospital

Completed

The Second-Generation MCCG for Upper Gastrointestinal Tract.

Capsule Endoscopy

China
McMaster University

Recruiting

Tryptophan for Impaired AhR Signaling in Celiac Disease (TIARSCeD)

Celiac Disease | Tryptophan Metabolism Alterations

Canada
The Hospital District of Satakunta

Completed

Vascular Healing After Deployment of Titanium-nitride-oxide-coated OPTIMAX™ Stent and PROMUS-ELEMENT™ Everolimus-Eluting Stent (TIDES-OCT)

Acute Coronary Syndrome

Finland
Maastricht University Medical Center
Top Institute Food and Nutrition

Completed

The Effect of Serotonergic Modulation on Intestinal Permeability and Visceral Hypersensitivity in Healthy Individuals and Irritable Bowel Syndrome (IBS) Patients

Irritable Bowel Syndrome

Netherlands
Société Française d'Endoscopie Digestive

Completed

Endocuff-assisted Colonoscopy vs Standard Colonoscopy on Adenoma Detection Rate (Cuff-Bercy)

Colonic Polyp | Colonoscopy | Colonic Adenoma

France
University of Texas Southwestern Medical Center
M.D. Anderson Cancer Center

Active, not recruiting

Second Generation LMA Versus Endotracheal Tube in Obese Patients

Obese | Endotracheal Tube | Laryngeal Mask Airway

United States
Institut de Recherche pour le Developpement
Institute of Tropical Medicine, Belgium; Institut National de Recherche Biomédicale... and other collaborators

Completed

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: Early Test-of-cure (DiTECT-WP4)

Trypanosoma Brucei Gambiense; Infection | African Trypanosomiasis | African; Trypanosomiasis, West | Sleeping Sickness; West African

Congo, The Democratic Republic of the
Per-Ola Carlsson

Completed

[11C]5-Hydroxy-tryptophan PET for Assessment of Islet Mass in Type 2 Diabetes

Type2 Diabetes
Ain Shams University

Completed

Histidine-Tryptophan-Ketoglutarate Solution Versus Blood Cardioplegia in CABG

Cardioplegia Solution Adverse Reaction

Egypt
University of Colorado, Denver

Completed

A Placebo Controlled Trial Of L-Tryptophan In Post-Operative Delirium

Post-operative Delirium

United States

Search clinical trials for: Antidepressive Agents, Second-Generation

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