Search clinical trials for: Antithrombins

Total 1143 results

Policlinico Hospital
The Mediterranean Institute for Transplantation and Advanced Specialized...

Completed

Antithrombin Supplementation in ECMO

Extracorporeal Membrane Oxygenation

Italy
Seoul National University Hospital

Completed

Antithrombin III Concentrate After Liver Transplantation

Liver Transplant; Complications

Korea, Republic of
Medical College of Wisconsin
Children's National Research Institute; rEVO Biologics

Terminated

Antithrombin III Supplementation for Cardiopulmonary Bypass in Neonates

Postoperative Hemorrhage

United States
University of Bari

Unknown

Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery (ATIII)

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Acute Coronary Syndrome | Mitral Valve Stenosis

Italy
Kyowa Kirin Co., Ltd.

Completed

An Open-label Study of KW-3357 (3357-004)

Disseminated Intravascular Coagulation (DIC)

Japan
rEVO Biologics

Completed

Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia (PRESERVE-1)

Preeclampsia

United States
Children's Hospital Los Angeles

Withdrawn

Pharmacokinetic Study of Recombinant AT III in Neonates Undergoing ECMO

Neonates on ECMO

United States
Seoul National University Hospital

Active, not recruiting

Antithrombin-III for Patients With Hepatic Veno-occlusive Diseases Following Hematopoietic Stem Cell Transplantation

Hepatic Veno-Occlusive Disease

Korea, Republic of
Kyowa Kirin Co., Ltd.
Japan Blood Products Organization

Completed

KW-3357 Study in Patients With Early Onset Severe Preeclampsia

Preeclampsia

Japan
SK Chemicals Co., Ltd.
Korea University Anam Hospital

Completed

Phase1 Syudy to Evaluate the Safety and PK/PD of Human Antithrombin III

Healthy

Korea, Republic of
rEVO Biologics

Completed

Recombinant Human Antithrombin (rhAT) in Patients With Hereditary Antithrombin Deficiency Undergoing Surgery or Delivery

Antithrombin III Deficiency

United States, France, United Kingdom, Germany, Canada, Austria, Australia, Italy
Octapharma

Not yet recruiting

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

Acquired Antithrombin Deficiency
Maimónides Biomedical Research Institute of Córdoba

Completed

Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19

Severe Acute Respiratory Syndrome | Covid19 | Distress Respiratory Syndrome

Spain
Mayo Clinic
rEVO Biologics

Terminated

Response of Recombinant Antithrombin in Heparin Resistant Patients Undergoing Cardiac Surgery

Thrombophilia Due to Acquired Antithrombin III Deficiency

United States
Grifols Therapeutics LLC
Covance; Clinipace Worldwide

Completed

Safety and Efficacy of Preoperative Antithrombin Supplementation in Patients Undergoing High-Risk Cardiopulmonary Bypass

Cardiac Surgery | Cardiopulmonary Bypass

United States
LEO Pharma

Terminated

Recombinant Human Antithrombin (ATryn®) in the Treatment of Patients With DIC Associated With Severe Sepsis

Disseminated Intravascular Coagulation
rEVO Biologics

Completed

Assess Incidence of Deep Vein Thrombosis(DVT)Following Administration of Recombinant Human Antithrombin (rhAT) to Hereditary Antithrombin(AT) Deficient Patients in High Risk Situations. (rhAT)

Antithrombin Deficiency, Congenital

France, United Kingdom, Germany, United States, Sweden, Italy
Octapharma

Recruiting

Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery

Congenital Antithrombin Deficiency

Spain, United States, Italy, France, Hungary, Austria, Germany, United Kingdom
Vastra Gotaland Region
Octapharma

Withdrawn

Atenativ Effect on Uterine Blood Flow and Preeclampsia

Antithrombin III Deficiency

Sweden
Sanofi

Recruiting

A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia (ATLAS-NEO)

Hemophilia

Greece, Korea, Republic of, France, Taiwan, Italy, Spain, United States, Canada, China, Germany, India, Japan, Mexico, South Africa, Turkey, Poland
Dr. Siyami Ersek Thoracic and Cardiovascular Surgery...

Completed

Prospective Investigation of Antithrombin III Deficiency in Adult Patients With ECMO

Extracorporeal Membrane Oxygenation Complication | Antithrombin III Deficiency

Turkey
Children's Hospital Medical Center, Cincinnati
Grifols Biologicals, LLC

Completed

Evaluation Of The Pharmacokinetics Of Antithrombin III In Neonates And Infants Undergoing CPB And ECMO Support

Cardiopulmonary Bypass | Extracorporeal Membrane Oxygenation Complication

United States
Asan Medical Center

Completed

Antithrombin III and Post-liver Transplantation Acute Kidney Injury

Liver Transplantation and Antithrombin

Korea, Republic of
Enrique Ginzburg
Grifols Biologicals, LLC

Terminated

Antithrombin III in Infectious Disease Caused by COVID-19

Covid19 | Antithrombin III Deficiency

United States
Sanofi

Recruiting

A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously Received Preventive Treatment With Emicizumab

Hemophilia A

Taiwan
Jonathan Stine
Grifols Therapeutics LLC

Withdrawn

Preventing de Novo Portal Vein Thrombosis With Antithrombin-III in Patients With Cirrhosis (PiVoT)

Cirrhosis, Liver | Portal Vein Thrombosis

United States
Assiut University

Unknown

Haemostatic Imbalance in Patients With Chronic Liver Disease

Haemostasis Imbalance in Chronic Liver Disease
The Hospital for Sick Children

Completed

Antithrombin Enhancement May Improve Anticoagulation Efficiency in Infants Undergoing Cardiopulmonary Bypass for Cardiac Surgery

Cardiopulmonary Bypass

Canada
Octapharma

Completed

Observational, Retrospective Study to Evaluate Coagulation Changes and the Influence of Antithrombin III Treatment in Patients With Severe COVID-19 Infection

Covid19

Austria, France, Germany, Sweden
Instituto Grifols, S.A.

Completed

Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass

Coronary Artery Bypass | Acquired Antithrombin III Deficiency

Italy
Duke University
Grifols Biologicals, LLC

Completed

Anti-thrombin III (ATIII) vs Placebo in Children (<7mo) Undergoing Open Congenital Cardiac Surgery

ATIII Deficiency

United States
University of Rochester

Terminated

Antithrombin III in Infants With Cardiopulmonary Bypass (CPB)

Congenital Heart Disease

United States
Karadeniz Technical University

Completed

Raloxifene on Coagulation System in the Postmenopausal Women

Postmenopausal Women | Raloxifene
Massachusetts General Hospital
rEVO Biologics

Completed

Understanding "Heparin Resistance" in Cardiac Surgery

Cardiopulmonary Bypass | Altered Heparin Response

United States
Nektar Therapeutics

Recruiting

NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma

Non-Hodgkin Lymphoma | Relapsed/Refractory Diffuse Large B-cell Lymphoma

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL)

Reperfusion Injury

Belgium
Centre d'Etudes et de Recherche pour l'Intensification...
University Hospital, Grenoble

Completed

Multicenter Assessment of the PDA-FIT System in Type 1 Diabetic Patients (TELEDIAB-1)

Type 1 Diabetes

France
Universitaire Ziekenhuizen KU Leuven

Completed

Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL) (CAPITL)

Reperfusion Injury

Belgium
Ottawa Hospital Research Institute
Mayday Fund

Enrolling by invitation

Prehospital Inhaled Methoxyflurane Non-Clinical Occupational Exposure Study

Occupational Exposure

Canada
Centre Hospitalier Universitaire de la Réunion

Completed

Use of Public Health Surveillance Models in the French National Health System Database (DABI-SURV)

Atrial Fibrillation | Anticoagulants | Pharmacoepidemiology

France
Boehringer Ingelheim

Completed

ReAHEAD: A Study to Find Out Whether Education Improves Adherence to Dabigatran in People With Atrial Fibrillation Who Are Younger Than 75 Years

Atrial Fibrillation

Taiwan
Boston Children's Hospital

Recruiting

Pharmacokinetics of Bivalirudin for Pediatric Anticoagulation

Drug Effect

United States
Ohio State University

Recruiting

Achieving Nutritional Adequacy Of Vitamins E and K With An Egg/Plant-Based Food Pairing - Study 1

Nutritional Requirements

United States
HaEmek Medical Center, Israel

Completed

ACRIPAB- Trial: Anti Coagulation Regimen In High Risk PAtients for Bleeding (ACRIPAB)

Hematologic Diseases

Israel
Institute of Liver and Biliary Sciences, India

Recruiting

Efficacy and Safety of Dabigatran in Patients With Cirrhosis and Portal Vein Thrombosis

Liver Cirrhosis | Portal Vein Thrombosis

India
Boehringer Ingelheim

Completed

Tolerability , PK/PD and Safety of Dabigatran Etexilate Oral Liquid Formulation in Children < 1 Year of Age

Venous Thromboembolism

Canada, France, Russian Federation
S. Andrea Hospital

Unknown

Safety Study of Dabigatran in CADASIL (SONICA)

CADASIL

Italy
Brigham and Women's Hospital

Completed

Replication of the RECOVER-II Anticoagulant Trial in Healthcare Claims Data

Venous Thromboembolism

United States
Ural State Medical University
Boehringer Ingelheim

Unknown

Evaluation of Abbreviated Versus Conventional Course of Dabigatran Etexilate Before Electric Cardioversion in Patients With Atrial Fibrillation (RE-SOUND Study) (RE-SOUND)

Atrial Fibrillation

Russian Federation
Boehringer Ingelheim

Completed

Safety and Tolerability of Dabigatran Etexilate in Adolescents

Venous Thromboembolism

Canada

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