Search clinical trials for: ascending dose of GSK1292263

Total 4177 results

GlaxoSmithKline

Completed

A Study in Healthy Volunteers of Single Doses of Orally Administered Investigational Product to Investigate Safety, Tolerability, and Pharmacokinecs.

Dyslipidaemias

United States
Bristol-Myers Squibb
Cardioxyl Pharmaceuticals, Inc

Completed

A First-in-Human Study of the Safety of Single Continuous Intravenous (IV) Infusions of CXL-1427 for up to 48 Hours in Healthy Volunteers

Heart Failure
Guangzhou Henovcom Bioscience Co. Ltd.

Completed

A Study of HNC042 in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics.

Healthy

United States
Galapagos NV

Completed

First-in-Human Single and Multiple Dose of GLPG1837

Healthy

Belgium
GEN İlaç ve Sağlık Ürünleri A.Ş.
Sulfateq B.V.

Recruiting

A First-In-Human Study of Single and Multiple Ascending Doses of Oral SUL-238 in Healthy Subjects

Healthy Subjects

Turkey
Enterome
Quotient Clinical

Completed

First-in-Human Single and Multiple Dose of EB8018

Healthy Volunteers

United Kingdom
Galapagos NV

Completed

First-in-Human Single and Multiple Dose of GLPG1972

Healthy

Belgium
Jiangsu Sinorda Biomedicine Co., Ltd

Completed

Single-dose and Multiple-dose X842 Phase 1 Study

Healthy Volunteers

China
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Inhaled CHF6001 (CHF6001Ext)

Chronic Obstructive Pulmonary Disease

United Kingdom
Hanmi Pharmaceutical Company Limited

Completed

Safety,PK/PD, Food Effect Study of Orally Administered HM71224 in Healthy Adult Male Volunteers

Rheumatoid Arthritis

Netherlands
OliPass Corporation

Completed

OLP-1002 is Being Studied in the Treatment of Pain.

Pain

United Kingdom
Nanjing Immunophage Biotech Co., Ltd
Novotech (Australia) Pty Limited

Not yet recruiting

A Study of Orally Administered IPG7236 in Healthy Adult Participants

Atopic Dermatitis

Australia
7 Hills Pharma, LLC
Frontage Clinical Services, Inc.

Completed

A Phase 1 SAD and MAD Study of the Safety, Tolerability and PK of 7HP349 in Normal Healthy Male Subjects

Solid Tumor

United States
Hoffmann-La Roche

Completed

A Study With RO4917523 in Patients With Fragile X Syndrome

Fragile X Syndrome

United States
Galapagos NV

Completed

First-in-Human Single and Multiple Dose of GLPG1690

Healthy

Belgium
Future Medicine

Completed

A SAD, MAD, and FE Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Profile of FM101 in Healthy Volunteers

Healthy Subjects

Netherlands
Société des Produits Nestlé (SPN)

Completed

Oral CDX-7108 in Healthy Adults and EPI Subjects

Exocrine Pancreatic Insufficiency

Australia, New Zealand
Bristol-Myers Squibb

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of BMS-986326 in Healthy Participants

Healthy Participants

Germany
Galapagos NV

Completed

First-in-Human Single and Multiple Dose of GLPG1205

Healthy

Belgium
Jiangsu Yahong Meditech Co., Ltd aka Asieris

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of APL-1501 Extended Release (ER) Capsules Compared to APL-1202 Immediate Release (IR) Tablets in Healthy Volunteers

Bladder Cancer

Australia
Nexel Co., Ltd.
Novotech (Australia) Pty Limited

Completed

A Study of NP-011 in Healthy Volunteers

Myocardial Infarction

Australia
Galapagos NV
MorphoSys AG

Completed

First in Human of Single and Multiple Doses of MOR106

Healthy | Dermatitis, Atopic

Belgium, Hungary, Moldova, Republic of, Romania
Stoke Therapeutics, Inc

Completed

An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome

Dravet Syndrome

United States
Cinclus Pharma AG

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of X842 in Human: A Single/Multiple Ascending Dose Study

Healthy Volunteers

Sweden
iOnctura

Completed

A Study to Assess an ATX Inhibitor (IOA-289) in Healthy Volunteers

Healthy

Italy
Pfizer

Active, not recruiting

A Preliminary Study to Evaluate PF-07264660 in Healthy Participants

Healthy

United States
Ornovi, Inc.

Withdrawn

A First in Human Single and Multiple Ascending Dose and Open Label Food Effect Study of OR-101 in Healthy Subjects

Alopecia Areata

Australia
Pfizer

Completed

Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979.

Healthy Subjects

Belgium
Pfizer

Completed

First-In-Human Study Of Single And Multiple Ascending Doses Of PF-06751979

Healthy Subjects

United States
Samsung Medical Center

Completed

Accuracy of Pre-existing Risk Scoring Models for Predicting Acute Kidney Injury in Patients Who Underwent Aortic Surgery Using a Gray Zone Approach

Aortic Surgery | Postoperative Acute Kidney Injury

Korea, Republic of
Gilead Sciences

Completed

A Study Evaluating GS-9620 in Treatment Naive Subjects With Chronic Hepatitis B

Hepatitis B | HBV

Korea, Republic of, United States, Canada, Australia, New Zealand
Gilead Sciences

Completed

A Study Evaluating GS-9620 in Treatment Naive Subjects With Chronic Hepatitis C

Hepatitis C

United States, Puerto Rico
Praxis Precision Medicines

Active, not recruiting

A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy

Epilepsy | SCN2A-DEE

United States
Immunocore Ltd

Recruiting

Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection

Hepatitis B, Chronic

Hong Kong, Korea, Republic of, Taiwan, Denmark, United States, Australia, Romania, United Kingdom, Spain
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Administering Multiple Oral Doses of GSK1292263 Alone and With Atorvastatin

Dyslipidemias | Dyslipidaemias

United States
Gilead Sciences

Completed

A Study Evaluating GS-9620 in Virologically Suppressed Subjects With Chronic Hepatitis B Virus Infection

Hepatitis B

Korea, Republic of, United States, Canada, Australia, New Zealand
Asana BioSciences

Completed

A Study of ASN007 in Patients With Advanced Solid Tumors

Cancer | Neoplasm Metastasis | Pancreatic Cancer | Metastatic Cancer | Metastatic Lung Cancer | Pancreas Adenocarcinoma | Metastatic Melanoma | Colon Cancer | Colonic Neoplasms | Pancreas Cancer | Non Small Cell Lung Cancer Metastatic | Neoplasm | Pancreas Neoplasm | Metastatic Pancreatic Cancer | Metastatic Colon Cancer and other conditions

United States
AstraZeneca

Completed

Single Centre, Double-blind, Single and Multiple Ascending Inhaled Doses of AZD9819 in Healthy Subjects

Healthy Volunteers | Tolerability | Safety

United Kingdom
Amplia Therapeutics Limited

Recruiting

ACCENT: AMP945 in Combination With Nab-paclitaxel and Gemcitabine for Treatment of Pancreatic Cancer

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | PDAC

Australia, Korea, Republic of
Second Affiliated Hospital, School of Medicine,...

Recruiting

Preoperative Stereotactic Body Radiotherapy (SBRT) Followed by Hepatectomy for Centrally Located Hepatocellular Carcinoma: a Prospective, Single-center, Phase I Study

Hepatectomy | Stereotactic Body Radiotherapy | Centrally Located Hepatocellular Carcinoma

China
GlaxoSmithKline

Completed

A Study in Type 2 Diabetic Subjects on Stable Metformin Therapy to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Co-administering Single and Multiple Oral Doses of GSK1292263

Diabetes Mellitus, Type 2

United States
Asana BioSciences

Terminated

Study of ASN003 in Subjects With Advanced Solid Tumors

Melanoma | Neoplasms | Colorectal Neoplasm | Carcinoma, Non-small Cell Lung

United States
Georgia State University

Recruiting

Biphasic Effects of Acute Alcohol Intoxication on Bystander Intervention

Alcohol Intoxication

United States
University of Minnesota

Recruiting

Seasonal Influenza Vaccine High Dose Boosting in Solid Organ Transplant Recipients

Solid Organ Transplant

United States
San Diego State University

Completed

Effect of Stair Climbing and Descending on Postprandial Blood Glucose

Postprandial Blood Glucose

United States
Stony Brook University

Completed

Benefit of CoQ-10 in Patients on Statins (CoQ-10)

Pain | Fatigue | Weakness | Soreness

United States
GlaxoSmithKline

Completed

A Study in Type 2 Diabetics of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

Diabetes Mellitus, Type 2

United States
Sinovac Biotech Co., Ltd

Completed

Clinical Trial of Recombinant Hepatitis B Vaccine (Hansenula Polymorpha, 10μg)

Hepatitis B

China
Pontificia Universidad Catolica de Chile

Recruiting

Immune Response to Third Dose of SARS-CoV-2 Vaccine in a Cohort of Cancer Patients on Active Treatment

Sars-CoV-2 Infection

Chile
Jiangsu Province Centers for Disease Control and...
Academy of Military Medical Sciences，Academy of Military Sciences，PLA; ZHONGYIANKE... and other collaborators

Recruiting

Phase I Trial of a Recombinant COVID-19 Vaccine (CHO Cell)

COVID-19

China

3

Subscribe