Search clinical trials for: Avastin® (bevacizumab)

Total 16045 results

Massachusetts General Hospital

Completed

Bevacizumab for Treatment of Recurrent Respiratory Papillomatosis (RRP)

Recurrent Respiratory Papillomatosis

United States
mAbxience Research S.L.

Completed

A Pharmacokinetic Study Comparing MB02 And US And EU Avastin® In Healthy Male Volunteers

Healthy Volunteers

United Kingdom
mAbxience Research S.L.

Completed

Pharmacokinetic Study Comparing MB02 And US And EU Avastin® In Healthy Male Volunteers

Healthy Volunteers

Germany
Shanghai Henlius Biotech

Completed

Pharmacokinetic, Safety and Immunogenicity Phase I Study of HLX04 Versus Avastin® in Healthy Male Subjects

Healthy Male Subjects

China
Reza Dana, MD
United States Department of Defense; New York Presbyterian Hospital; Bascom Palmer...

Completed

A Multi-Center Study of the Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival

Corneal Neovascularization | Corneal Graft Failure

United States
Cipla BioTec Pvt. Ltd.
Quintiles, Inc.

Unknown

PK Bioequivalence Single-dose Safety Tolerability Study in Healthy Male Volunteers to Compare CBT124 & Avastin(EU&US) (CBT124NHV001)

Healthy

New Zealand
Ophthotech Corporation

Terminated

A 24 Month Phase 2a Open Label, Randomized Study of Avastin®, Lucentis®, or Eylea® (Anti-VEGF Therapy) Administered in Combination With Fovista® (Anti-PDGF BB Pegylated Aptamer)

Age-Related Macular Degeneration

United States
University of Colorado, Denver
Genentech, Inc.

Terminated

The Role of Bevacizumab in the Treatment of Radiation Necrosis in Children With Central Nervous System Tumors

Radiation Necrosis

United States
Samsung Bioepis Co., Ltd.

Completed

Pharmacokinetic, Safety, Tolerability, and Immunogenicity Study of SB8 in Healthy Male Subjects

Healthy

Belgium
Klinikum Bremen-Mitte, gGmbH
Kompetenzzentrum für Klinische Studien, Bremen

Unknown

Prevention of Vision Loss in Patients With Age-Related Macular Degeneration (AMD) by Intravitreal Injection of Bevacizumab and Ranibizumab (VIBERA)

Age-Related Neovascular Macular Degeneration

Germany
Hoffmann-La Roche

Completed

A Dose- and Efficacy-Finding Study of RO5323441 in Combination With Avastin (Bevacizumab) in Patients With Recurrent Glioblastoma

Glioblastoma Multiforme

Switzerland, France, United Kingdom, Denmark
Reza Dana, MD

Completed

Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival

Corneal Neovascularization | Corneal Graft Failure

United States
Ophthotech Corporation

Terminated

A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Either Avastin® or Eylea® Compared to Avastin® or Eylea® Monotherapy

Age-Related Macular Degeneration

France, Israel, Italy, United States, Spain, Portugal, Germany, Austria, Canada, Czechia, Estonia, Latvia, Poland, Slovakia, Australia, Hungary, Croatia, Argentina, Finland, Brazil, Colombia, Norway
Providence Health & Services
Bristol-Myers Squibb; Genentech, Inc.

Terminated

Trial of Bevacizumab and Ixabepilone for Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

Non-squamous Non-small Cell Lung Cancer

United States
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Compare IBI305 and Bevacizumab on Pharmacokinetics/Safety/Immunogenicity on Healthy Male

Healthy

China
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Satraplatin and Bevacizumab in Treating Patients With Metastatic Prostate Cancer Previously Treated With Docetaxel

Prostate Cancer

United States
Northwell Health
Feinstein Institute for Medical Research; Hofstra North Shore

Suspended

Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Vestibular Schwannoma

Vestibular Schwannoma

United States
Ronald Hoffman
National Cancer Institute (NCI); Myeloproliferative Disorders-Research Consortium

Terminated

Phase II Study of Bevacizumab (Avastin®) in Myelofibrosis

Myelofibrosis

United States
Children's Hospital Los Angeles

Temporarily not available

Use of Pan-Vascular Endothelial Growth Factor Receptor (Pan-VEGF) Blockade for the Treatment of Retinopathy of Prematurity (ROP) (Compassionate Use BLOCK-ROP)

Retinopathy of Prematurity

United States
mAbxience Research S.L.

Unknown

A Study Comparing the Pharmacokinetic Similarity of MB02-SP, MB02-DM and USlicensed Avastin®.

Healthy Volunteers

New Zealand
Grupo Espanol Multidisciplinario del Cancer Digestivo

Unknown

Efficacy/Safety Study of Bevacizumab,Capecitabine,Oxaliplatin to Metastatic Colorectal Adenocarcinoma Elderly Patients. (BECOX)

Metastatic Colorectal Cancer

Spain
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); Sanofi; Genentech, Inc.

Completed

Avastin in Combination With Docetaxel in Ovarian/Fallopian Tube/Peritoneum Carcinoma

Ovarian Cancer | Fallopian Tube Cancer | Malignant Tumor of Peritoneum

United States
Hanny Al-Samkari, MD

Recruiting

Bevacizumab In Hereditary Hemorrhagic Telangiectasia

Hereditary Hemorrhagic Telangiectasia

United States
Swiss Group for Clinical Cancer Research

Terminated

Bevacizumab in Treating Patients Who Have Undergone First-Line Therapy for Metastatic Colorectal Cancer

Colorectal Cancer

Switzerland
University of Sao Paulo

Completed

Bevacizumabe or Triamcinolone for Persistent Diabetic Macular Edema (BEVATAAC)

Diabetic Macular Edema
University of Southern California

Completed

Avastin for PDR (Proliferative Diabetic Retinopathy) (PDR)

Diabetic Retinopathy | Retinal Detachment

United States
University of Utah
Genentech, Inc.

Completed

Bevacizumab (Avastin®) + Erlotinib as First-line Therapy for Stage IIIB/IV or Recurrent, Non-squamous Cell Lung Cancer

Cancer

United States
Universidad Autonoma de San Luis Potosí

Unknown

Bevacizumab 0.500MG Intravitreal There Isn't Lower Than 0.625MG in the Treatment of ROP Type 1 (Bevacizumab)

Retinopathy of Prematurity

Mexico
mAbxience Research S.L.

Completed

A Pharmacokinetic Study Comparing MB02 And EU Avastin® In Healthy Male Volunteers

Healthy Volunteers | Male | Japanese

Japan
Hoffmann-La Roche

Completed

A Study Examining Maintenance Bevacizumab (Avastin®) Monotherapy in Participants With Advanced Lung Adenocarcinoma

Lung Adenocarcinoma

Hungary
Instituto Universitario de Oftalmobiología Aplicada...

Completed

Initial Treatment With Bevacizumab in Choroidal Neovascularization Associated to High Myopia (BENEMCOR)

Choroidal Subfoveal/Juxtafoveal Neovascularization in High Myopia

Spain
Celltrion

Completed

To Demonstrate Similarity of Pharmacokinetics and Evaluate Safety of CT-P16, EU-Approved Avastin and US-licensed Avastin

Healthy

Korea, Republic of
Lynn E. Spitler, MD
Genentech, Inc.; Celgene Corporation

Completed

Abraxane and Avastin as Therapy for Patients With Malignant Melanoma, a Phase II Study (AbraxAvast)

Metastatic Malignant Melanoma

United States
Novartis Pharmaceuticals

Completed

Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Agerelated Macular Degeneration (AMD) Who Received Anti-VEGF Agents (IRIS Registry)

Age-related Macular Degeneration (AMD)

United States
Hoffmann-La Roche

Completed

Study to Evaluate Safety, Pharmacokinetics and Therapeutic Activity of RO6874281 as a Combination Therapy in Participants With Unresectable Advanced and/or Metastatic Renal Cell Carcinoma (RCC)

Renal Cell Carcinoma

Korea, Republic of, United Kingdom, Denmark, France, Spain, Canada, United States, Germany, Italy
Sanofi

Completed

TEACO: Taxotere, Eloxatin, Avastin in Cancer of the Ovary (TEACO)

Ovarian Cancer

United States
Novartis Pharmaceuticals

Completed

Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Age-related Macular Degeneration (AMD) Who Received Anti-vascular Endothelial Growth Factor (VEGF) Agents (Komodo Health)

Age-related Macular Degeneration (AMD)

United States
Retinal Consultants of Arizona
Ophthotech Corporation

Completed

An Open-Label Investigator Sponsored Trial to Investigate the Safety, Tolerability and Development of Subfoveal Fibrosis By Intravitreal Administration of Altering Regimens of Fovista and Anti-VEGF Therapy in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Qilu Pharmaceutical Co., Ltd.

Not yet recruiting

A Study to Compare the Pharmacokinetics and Safety of QL1101 and EU-Avastin® in Healthy Volunteers

Tumor

China
Lawson Health Research Institute
QLT Inc.; Canadian Retinal Trials Group

Completed

Combination Therapy for Age-Related Macular Degeneration.

Age Related Macular Degeneration

Canada
PD Dr. med. Wolfgang Schuette
Eli Lilly and Company; Roche Pharma AG

Completed

Efficacy Study of Avastin® With Pemetrexed +/- Carboplatin to Treat Elderly Patients With Non-small Cell Lung Cancer (65plus)

Non-squamous Non-small Cell Lung Cancer

Germany
Mayo Clinic

Withdrawn

Reduction of Plasma Free VEGF-A Using Low-dose Bevacizumab in Hemodialysis Patients

End Stage Renal Disease | Hemodialysis Vascular Access Failure
TRPHARM

Withdrawn

Bioequivalence and Safety Study of Bevacizumab-biosimilar (RPH-001) Compared to Bevacizumab-innovator

Healthy
Amgen

Completed

PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study

Cancer | Metastatic Colorectal Cancer | Colorectal Cancer | Neutropenia | Fever | Rectal Cancer | Colon Cancer | Locally Advanced

United States, Belgium, Czechia, Canada, Hungary, Poland, Russian Federation, Ukraine, Bulgaria, Romania, Australia, Ireland, France, Slovakia, Latvia, Italy, Mexico
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

A Phase I Clinical Trial of Bevacizumab Injection

Cervical Cancer | Glioblastoma | Ovarian Cancer | Lung Cancer | Rectal Cancer

China
iOMEDICO AG
Roche Pharma AG; Arbeitsgemeinschaft fur Internistische Onkologie; Arbeitskreis...

Completed

Capecitabine and Bevacizumab ± Vinorelbine in Metastatic Breast Cancer (CARIN)

Metastatic Breast Cancer

Germany
Mylan Pharmaceuticals Inc

Completed

MYL-1402O Compared With Avastin®, in Patients With Stage IV nsNSCLC

NSCLC Stage IV

Turkey, Taiwan, Vietnam, Croatia, India, Russian Federation, Spain, Hungary, Bosnia and Herzegovina, Ukraine, Poland, Romania, Belarus, Bulgaria, Georgia, Italy, Philippines
Eli Lilly and Company

Terminated

Cetuximab and Bevacizumab With or Without Gemcitabine to Treat Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer

United States
GlaxoSmithKline

Completed

Incidence, Prevalence, and Symptom Burden Associated With Advanced Renal Cell Carcinoma in Commercially Insured Population (Pharmetrics)

Carcinoma, Renal Cell
Swiss Group for Clinical Cancer Research

Completed

Bevacizumab, Pemetrexed Disodium, and Cisplatin or Erlotinib Hydrochloride and Bevacizumab in Treating Patients With Stage IV Non-Small Cell Lung Cancer. A Multicenter Phase II Trial Including Biopsy at Progression (BIO-PRO Trial).

Lung Cancer

Switzerland

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