Search clinical trials for: BQ-123 and BQ-788

Total 2170 results

University of Edinburgh
Umeå University

Completed

The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin

Coronary Disease

Sweden
Medical University of Vienna

Completed

Endothelin-Receptor Blockade in Coronary Heart Disease

Vascular Resistance | Coronary Vessels | Endothelins

Austria
University Hospital, Rouen

Completed

Role of Endothelin-1 in Flow-mediated Dilatation (Endothelin)

Healthy Conditions

France
University of Colorado, Boulder
Forest Laboratories

Completed

Nebivolol and the Endothelin (ET)-1 System (NETS)

Hypertension | Prehypertension

United States
BrainQ Technologies Ltd.

Completed

The Efficacy of a Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Subacute Ischemic Stroke Patients - a Pivotal Study (THE "EMAGINE" STUDY) (BQ5)

Ischemic Stroke

United States
The University of Texas at Arlington

Recruiting

The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction

Cardiovascular Diseases | Cardiovascular Risk Factor | Vasoconstriction

United States
BrainQ Technologies Ltd.
Sheba Medical Center; The Miami Project to Cure Paralysis; Kessler Institute...

Recruiting

The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients

Incomplete Spinal Cord Injury

Israel, United States
BrainQ Technologies Ltd.

Terminated

Efficacy of EMF BCI Based Device on Acute Stroke

Acute Stroke

India
Brigham and Women's Hospital

Completed

The Role of Endothelin in Pulmonary Hypertension

Pulmonary Hypertension

United States
Mayo Clinic

Completed

Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI (BQ-123)

Myocardial Reperfusion Injury

United States
MelCure SA
Universitaire Ziekenhuizen KU Leuven; University of Bern; California Institute...

Terminated

Proof of Concept Study With an Endothelin Receptor B Inhibitor (BQ-788) for Human Melanoma

Melanoma
VA Office of Research and Development
University of Utah

Completed

Contribution of Endothelin-1 to Exercise Intolerance in Heart Failure

Heart Failure

United States
Brigham and Women's Hospital

Completed

The Contribution of Endothelin to Vasomotor Function in Diseased Coronary Arteries

Atherosclerosis, Coronary

United States
National Taiwan University Hospital

Recruiting

Comparison of Vonoprazan-based Versus Lansoprazole-based Triple Therapy, High Dose Dual Therapy, Bismuth and Non-bismuth Quadruple Therapy in the First-line Treatment of Helicobacter Pylori Infection

H. Pylori Infection

Taiwan
Bioquark Inc.
Revita Life Sciences; Anupam Hospital

Completed

Non-randomized, Open-labeled, Interventional, Single Group, Proof of Concept Study With Multi-modality Approach in Cases of Brain Death Due to Traumatic Brain Injury Having Diffuse Axonal Injury

Brain Death

India
Vanderbilt University

Withdrawn

The Role of Endothelin in the Supine Hypertension of Autonomic Failure

Hypertension | Multiple System Atrophy | Pure Autonomic Failure

United States
Dow University of Health Sciences

Completed

Behavior Changing Intervention for Smokeless Tobacco and Betel Quid Use in Adolescents

Oral Cavity Carcinoma

Pakistan
University of Southern Denmark
The University of Texas at Arlington

Active, not recruiting

Insulin Stimulated Vasodilation in Patients With Type 2 Diabetes

Type2 Diabetes

Denmark
Medical University of Vienna

Completed

Role of Endothelin-1 in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy Humans

Healthy

Austria
Medical University of Vienna

Recruiting

Landiolol for Prevention of Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery (LANDI-POAF)

Postoperative Complications | Atrial Fibrillation

Austria
Medical University of Vienna

Unknown

Short-term Endothelin A Receptor Blockade in Patients With On-pump CABG

Coronary Artery Disease | Aorto-coronary Bypass Grafting

Austria
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline

Completed

Evaluating the Effect of Standard-of-care Erythropoiesis-stimulating Agents on Forearm Blood Flow in Nondialysis-dependent Subjects With Anaemia Associated With Chronic Kidney Disease. (OPERA-CKD)

Cardiovascular Diseases | Chronic Kidney Disease

United Kingdom
Assistance Publique - Hôpitaux de Paris
Association Française contre les Myopathies (AFM), Paris; ARS (Association... and other collaborators

Completed

Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls (DOSERAL)

Amyotrophic Lateral Sclerosis

France
Medical University of Vienna

Completed

Endothelin Receptor Blockade in Acute ST-elevation Myocardial Infarction

ST-Elevation Myocardial Infarction

Austria
University of Edinburgh
British Heart Foundation

Completed

Endothelin Receptor Antagonism in Proteinuric Nephropathy

Proteinuria | Chronic Kidney Disease

United Kingdom
Ake Norberg

Completed

A Prospective Validation Study of Albumin Kinetics With Tracer 123 I-HSA

Healthy | SIRS

Sweden
GTx

Completed

Study of the Effect of GTx-758 on Serum PSA and Testosterone in Men With Prostate Cancer

Prostate Cancer

United States
Institute for Neurodegenerative Disorders
United States Department of Defense; University of Oklahoma

Completed

Development of Cognitive Assessment Tools in Parkinson Disease (ANAM)

Parkinson Disease

United States
Biodel

Completed

Pharmacokinetic and Pharmacodynamic Properties of BIOD-123 and BIOD-125 Compared to Humalog® in Subjects With Type 1 Diabetes Including Assessments of Injection Site Toleration

Diabetes Mellitus
ModernaTX, Inc.

Completed

A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of mRNA-1283 and mRNA-1273 Vaccines in Healthy Adults Between 18 Years and 55 Years of Age to Prevent COVID-19

SARS-CoV-2

United States
Amsterdam UMC, location VUmc

Active, not recruiting

Rhenium-188-HEDP vs. Radium-223-chloride in Patients With Advanced Prostate Cancer Refractory to Hormonal Therapy (RaRe)

Prostate Cancer Metastatic to Bone

Netherlands
ModernaTX, Inc.

Completed

A Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Vaccine Boosters

SARS-CoV-2

United States
Bausch Health Americas, Inc.

Completed

A Phase 3, Vehicle-controlled Efficacy and Safety Study of IDP-123 Lotion in the Treatment of Acne Vulgaris (301)

Acne Vulgaris

United States, Canada
Bausch Health Americas, Inc.

Completed

A Phase 3, Vehicle-controlled Efficacy and Safety Study of IDP-123 Lotion in the Treatment of Acne Vulgaris (302)

Acne Vulgaris

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Ultrasound-Guided Implant Radiation Therapy in Treating Patients With Locally Recurrent Prostate Cancer Previously Treated With External-Beam Radiation Therapy

Prostate Cancer

United States, Canada
Bayer

Active, not recruiting

Drug Use Investigation of Xofigo, Castration Resistant Prostate Cancer With Bone Metastases

Prostatic Neoplasms, Castration-Resistant

Japan
National Taiwan University Hospital

Completed

Comparison of the Levofloxacin Sequential Therapy and Quadruple Therapy in Second Line Treatment for HP

Helicobacter

Taiwan
Russell Richardson

Recruiting

: Vascular Function in Health and Disease

Heart Failure | Hypertension | Chronic Obstructive Pulmonary Disease | Pulmonary Artery Hypertension

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Assess Absolute Bioavailability (ABA) of Mobocertinib (TAK-788) and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of Carbon-14 ([14C])-Mobocertinib in Male Healthy Participants

Healthy Volunteers

United States
Takeda

Active, not recruiting

A Study of TAK-788 in Adults With Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Spain, Korea, Republic of, Taiwan, Japan, China, Italy, Germany, United Kingdom, Puerto Rico
Asahi Kasei Pharma Corporation

Completed

Exploratory Study of ART-123 for the Prevention of Cancer Treatment Related Symptoms in Patients With Postoperative Stage II / III Colon Cancer

Postoperative Stage II/III Colon Cancer

Japan
Ottawa Heart Institute Research Corporation

Completed

Autonomic Innervation and MIBG Imaging (MIBG-AF)

Atrial Fibrillation

Canada
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic, Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer | Prostate Carcinoma Metastatic in the Bone

United States
Bausch Health Americas, Inc.

Completed

Absorption and Systematic Pharmacokinetics of IDP-123 Lotion in Comparison With Tazorac Cream

Acne

United States
Bayer
Merck Sharp & Dohme LLC

Terminated

Study to Test the Safety and How Radium-223 Dichloride an Alpha Particle-emitting Radioactive Agent Works in Combination With Pembrolizumab an Immune Checkpoint Inhibitor in Patients With Stage IV Non-small Cell Lung Cancer With Bone Metastases

Carcinoma, Non-Small-Cell Lung

Spain, Belgium, Netherlands, United States
University of Washington
Bayer

Recruiting

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8

United States
Molecular NeuroImaging
Institute for Neurodegenerative Disorders

Completed

Evaluation of [123I] AV83 and SPECT in Patients With Alzheimer Disease in Comparison to Healthy Controls

Alzheimers Disease

United States
Chang Gung Memorial Hospital

Completed

Serotonin Transporter Density in Late-life Depression With and Without Dementia

Melancholia
Institute for Neurodegenerative Disorders
Molecular NeuroImaging

Completed

Biodistribution and Safety of a Radiopharmaceutical in Healthy Subjects

Neurodegenerative Diseases

United States
Avanir Pharmaceuticals

Completed

A Phase-1 Study to Assess the Pharmacokinetics, Safety and Tolerability of AVP-786 in Healthy Volunteers

Healthy

Australia

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