Search clinical trials for: baclofen, intrathecal

Total 462 results

Assiut University

Not yet recruiting

Role of Functional Neurosurgery in Management of Spasticity

Functional Neurological Disorder
Amsterdam UMC, location VUmc
Medtronic

Not yet recruiting

Predictive Factors for Succes of ITB in CP

Cerebral Palsy | Intrathecal Baclofen
Maastricht University
Medtronic

Completed

Dutch National ITB Study in Children With Cerebral Palsy

Cerebral Palsy | Spasticity

Netherlands
Tanta University

Unknown

Baclofen in the Treatment of Muscle Cramps in Patients With Cirrhosis

Liver Cirrhosis | Muscle Cramps

Egypt
University of Missouri-Columbia

Withdrawn

Open Label Treatment of Severe Tactile Defensiveness With Intrathecal Baclofen

Autism Spectrum Disorder

United States
Seaside Therapeutics, Inc.

Terminated

An Open Label Extension Study of STX209 in Subjects With Autism Spectrum Disorders

Autism Spectrum Disorders

United States
MedtronicNeuro

Completed

SISTERS: Spasticity In Stroke Study - Randomized Study (SISTERS)

Severe Spasticity

Belgium, Spain, United States, Austria, Germany, Italy, Netherlands, Slovenia, United Kingdom
University Hospital, Ghent

Completed

Intrathecal Administration of Baclofen (ITB) to Cerebral Palsy Patients With Therapy-Resistant Spasticity

Cerebral Palsy

Belgium
Institut Guttmann
Medtronic

Completed

Intrathecal Baclofen (ITB) Bolus on Neuropathic Pain (NP). Preliminary Study. (ITB)

Neuropathic Pain

Spain
Celso Arango, MD, PhD
UMC Utrecht

Completed

Arbaclofen in Children and Adolescents With ASD (AIMS2-CT1)

Autism Spectrum Disorder

Spain, United Kingdom, France
Gonzalez-Heydrich, Joseph, M.D.
Boston Children's Hospital; Seaside Therapeutics, Inc.

Terminated

TMS Measures of Plasticity and Excitatory/Inhibitory Ratio as Biomarkers: R-baclofen Effects in Normal Volunteers

Autism

United States
Indivior Inc.

Completed

A Phase 1 Bioavailability Study of Arbaclofen Placarbil Modified Release Formulations in Healthy Volunteers

Healthy Volunteers

United Kingdom
Piramal Critical Care, Ltd.

Completed

Safety Study of 3 mg/mL Baclofen Injection (Intrathecal) Using A Programmable Pump

Severe Spasticity

United States
RVL Pharmaceuticals, Inc.
Osmotica Pharmaceutical US LLC

Completed

Efficacy Study of Arbaclofen to Treat Spasticity in Multiple Sclerosis

Multiple Sclerosis | Spasticity

United States, Russian Federation, Ukraine
Seaside Therapeutics, Inc.

Completed

Efficacy and Safety Study of STX209 (Arbaclofen) for the Treatment of Social Withdrawal in Children With Fragile X Syndrome (Harbor-C)

Fragile X Syndrome

United States
Seaside Therapeutics, Inc.

Completed

Study of Arbaclofen for the Treatment of Social Withdrawal in Subjects With Autism Spectrum Disorders

Autism Spectrum Disorders

United States
Seaside Therapeutics, Inc.

Terminated

An Open Label Extension Study of STX209 in Subjects With Fragile X Syndrome

Fragile X Syndrome

United States
XenoPort, Inc.

Completed

A Study to Evaluate the Safety and Tolerability of Arbaclofen Placarbil (XP19986) in Subjects With Acute Back Spasms

Back Pain

United States
Clinical Research Associates, LLC

Recruiting

Safety, Tolerability, and Efficacy of Arbaclofen in 16p11.2 Deletion

16P11.2 Deletion Syndrome

United States
XenoPort, Inc.

Completed

Efficacy and Safety of Arbaclofen Placarbil in Subjects With Spasticity Due to Multiple Sclerosis

Multiple Sclerosis

United States
XenoPort, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Canada
Tisch Multiple Sclerosis Research Center of New...

Completed

Intrathecal Administration of Autologous Mesenchymal Stem Cell-derived Neural Progenitors (MSC-NP) in Progressive Multiple Sclerosis

Multiple Sclerosis

United States
Moens Maarten

Completed

Virtual Reality During Intrathecal Pump Refills in Children (VAMPIRE)

Cerebral Palsy

Belgium
Impax Laboratories, LLC

Completed

IPX056 in Subjects With Established Spasticity Resulting From Multiple Sclerosis

Multiple Sclerosis

United States, Canada, Estonia, Latvia, Ukraine
Royan Institute

Completed

Intrathecal Transplantation of Mesenchymal Stem Cell in Patients With ALS

Amyotrophic Lateral Sclerosis

Iran, Islamic Republic of
International Stemcell Services Limited

Completed

Safety and Efficacy of Autologous Bone Marrow Stem Cells in Treating Spinal Cord Injury (ABMST-SCI)

Spinal Cord Injuries

India
Centre Hospitalier Universitaire de Nice

Active, not recruiting

Monitoring to the Evolution of Motor Function in SMA Type II Adults Patients Treated With SPINRAZA® (SMAII)

Spinal Muscular Atrophy

France
Dr med. Paolo Maino Viceprimario Anestesiologia
VU University of Amsterdam

Completed

Intrathecal Pump Refill Undergoing Regular Intrathecal Pump Refill

Chronic Pain

Switzerland
Vanderbilt University
Allergan; Medtronic

Completed

Vanderbilt University Spasticity Management Program Evaluation Plan

Spasticity

United States
University of Minnesota
Paralyzed Veterans of America Research Foundation

Completed

Oral and IV Baclofen in Adult Volunteers

Baclofen Withdrawal Syndrome

United States
Tisch Multiple Sclerosis Research Center of New...

No longer available

Expanded Access to Intrathecal Administration of Autologous Mesenchymal Stem Cell-derived Neural Progenitors (MSC-NP) in Progressive Multiple Sclerosis

Multiple Sclerosis

United States
Hospital Universitario Dr. Jose E. Gonzalez

Completed

Effect of Intrathecal Administration of Hematopoietic Stem Cells in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Mexico
Allaysis, LLC
University of Minnesota

Unknown

Repeated Dose IV Baclofen Safety/Bioequivalence Study

Intravenous Baclofen
University of Sao Paulo General Hospital
Pontifícia Universidade Católica do Paraná

Unknown

Study of Two Intrathecal Doses of Autologous Mesenchymal Stem Cells for Amyotrophic Lateral Sclerosis

AMYOTROPHIC LATERAL SCLEROSIS

Brazil
Hospices Civils de Lyon

Not yet recruiting

Baclofen for Improving Benzodiazepine Titration in Benzodiazepine Dependence (BABET)

Benzodiazepine Dependence

France
Tri Phuoc Biotechnology., JSC

Unknown

Transplantation of Autologous Adipose Derived Stem Cells (ADSCs) in Spinal Cord Injury Treatment

Acute Spinal Cord Injury

Vietnam
Cairo University

Unknown

Comparison of Different Doses of Dexmedetomidine Effect in the Duration of Spinal Anesthesia

Spinal Anesthesia Duration

Egypt
Saint Petersburg State University, Russia
Ural State Medical University

Recruiting

BTA vs Baclofen for Pelvic Myofascial Pain Syndrome (BvsB)

Chronic Pain | Pelvic Floor Disorders | Myofascial Pain Syndrome | Myofascial Trigger Point Pain | Chronic Pelvic Pain Syndrome

Russian Federation
Beijing Tiantan Hospital

Not yet recruiting

Safety and Preliminary Efficacy of Aleeto in Amyotrophic Lateral Sclerosis (SPECIALS)

Amyotrophic Lateral Sclerosis

China
Tanta University

Recruiting

Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric Surgery

Morbid Obesity | Postoperative Nausea and Vomiting | Laparoscopic Sleeve Gastrectomy

Egypt
Vanderbilt University
Medtronic

Completed

Intrathecal (IT) Baclofen Drug Distribution (ITB)

Muscle Spasticity

United States
Shaare Zedek Medical Center

Terminated

Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes?

Cerebral Palsy

Israel
Imperial College London
Medical Research Council

Completed

GABA-B Receptor Function in Healthy Volunteers

No Condition | Brain GABA-B Function

United Kingdom
University of Pennsylvania
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Baclofen Effects in Cigarette Smokers (BAC)

Nicotine Dependence

United States
Alkermes, Inc.

Completed

ALK29-002: A Study of Baclofen Formulations in Healthy Adults

Alcohol Dependence

United States
Tisch Multiple Sclerosis Research Center of New...

Completed

Intrathecal Administration of Autologous Mesenchymal Stem Cell-derived Neural Progenitors (MSC-NP) in Patients With Multiple Sclerosis

Multiple Sclerosis

United States
Centre for Addiction and Mental Health
Canadian Tobacco Control Research Initiative

Terminated

Baclofen for Smoking Cessation in a Non-Psychiatric Population (Baclofen)

Nicotine Dependence

Canada
XenoPort, Inc.

Completed

An Efficacy and Safety Study of XP19986 in Subjects With Symptomatic GERD

Gastroesophageal Reflux

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Intrathecal Catheter Placement Versus Resiting Epidural Catheter After Dural Puncture in Obstetric Patients (ItaREVI)

Post-Dural Puncture Headache | Analgesia, Obstetrical
agnes chen
University of California, Los Angeles; National Institute of Neurological Disorders... and other collaborators

Terminated

Extension Study of Intrathecal Enzyme Replacement for Cognitive Decline in MPS I

Mucopolysaccharidosis I | Cognitive Decline

United States

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