Search clinical trials for: Beta-Lactams

Total 6380 results

Chris Goss
Medical University of South Carolina; University of Washington; Cystic Fibrosis...

Recruiting

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study (STOP360AG)

Cystic Fibrosis | Cystic Fibrosis Pulmonary Exacerbation

United States, Canada
Hoffmann-La Roche

Completed

A Study of Beta-Lactam in Hospitalized Patients With Skin and Skin Structure Infections

Soft Tissue Infections

United States, Estonia, Peru, Germany, Bulgaria, South Africa, Latvia, Lithuania, Argentina, Hungary, Romania
Hoffmann-La Roche

Completed

A Study to Assess Beta-Lactam in the Treatment of Hospitalized Patients With Bacterial Pneumonia

Pneumonia, Bacterial

United States, Romania, Chile, Slovakia, Hungary, Bulgaria, Latvia, Croatia, Peru, Lithuania, Argentina
Meir Medical Center

Completed

Extended Open Challenge in Patients With a History of Drug Eruption Following Beta-lactam Treatment

Beta-lactam Allergy

Israel
Qianfoshan Hospital

Completed

Risk Factors and Machine Learning Model for Beta-Lactam Drugs Related Acute Kidney Injury

Acute Kidney Injury | Beta-Lactam Antibiotic Toxicity (Diagnosis)

China
University Hospital, Grenoble

Not yet recruiting

Pharmacokinetics and Modelling of Beta-Lactam in ECMO-VA Patients (KAMELOT)

Infections | Cardiac Arrest | Cardiogenic Shock | Extracorporeal Membrane Oxygenation Complication | Post-cardiac Surgery

France
Singapore General Hospital

Recruiting

Beta-lactam Therapeutic Drug Monitoring in Singapore (BLAST-2)

Infection, Bacterial

Singapore
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Vancomycin-Resistant Enterococci in a Hematology Unit

Gram-Positive Bacterial Infections

Korea, Republic of
Imperial College London

Completed

Beta-lactam Pharmacokinetics in Secondary Care

Pharmacokinetics | Penicillin Allergy | Beta Lactam Adverse Reaction

United Kingdom
Centre Hospitalier Universitaire de Besancon

Unknown

Impact of Number of Rank of B-lactam Antibiotics on Emergence on Multidrug Resistant Bacteria (INOR Blact)

Antibiotic Resistant Infection | Resistant Infection | Beta Lactam Resistant Bacterial Infection | Bacterial Resistance
Fundación Pública Andaluza para la gestión de la...

Unknown

Efficacy of Intravenous Fosfomycin in the Treatment of Complicated Urinary in Real-life Conditions.

Complicated Urinary Tract Infection

Spain
CPL Associates
Sanofi

Completed

Outcomes of Patients Not Responding to Antibiotics in the Community

Sinusitis | Pneumonia, Bacterial | Bronchitis, Chronic

United States
Allecra

Completed

Investigation of AAI101 Safety, Tolerability & PK in Healthy Volunteers

Healthy
Sara Thønnings

Withdrawn

Therapeutic Drug Monitoring and Continuous Infusion of Beta-lactam Antibiotics in Patients With Bacteraemia

Bacteremia
Swiss National Fund for Scientific Research
University Hospital, Geneva

Completed

Monotherapy Versus Bitherapy in Non-severe Hospitalized Community-acquired Pneumonia (BICAP)

Community-acquired Pneumonia

Switzerland
Menzies School of Health Research
The University of Queensland; Australasian Society for Infectious Diseases; Singapore... and other collaborators

Terminated

Combination Antibiotic Therapy for Methicillin Resistant Staphylococcus Aureus Infection (CAMERA2)

Methicillin-Resistant Staphylococcus Aureus

Australia, New Zealand, Israel, Singapore
National Taiwan University Hospital

Unknown

Evaluation of Extended Intravenous of Beta-lactams in the Treatment of Serious Gram-negative Infections in Critically Ill Patients

Gram-Negative Bacterial Infections

Taiwan
Mayo Clinic

Completed

Negative Predictive Value and NIC of Beta-Lactam Antibiotics.

Allergy

United States
Versailles Hospital

Unknown

Short Duration Treatment of Non-severe Community Acquired Pneumonia (PTC)

Community Acquired Pneumonia

France
Hellenic Institute for the Study of Sepsis

Recruiting

Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT) (REACT)

Community-acquired Pneumonia

Greece
First Affiliated Hospital Xi'an Jiaotong University
Second Affiliated Hospital of Xi'an Jiaotong University

Completed

Safety and Efficacy of Vancomycin Plus Beta-lactams (SEVPB)

Critical Illness

China
Assistance Publique - Hôpitaux de Paris

Terminated

Deescalating Carbapenems in Hospital Setting (CARBEPARGNE)

Urinary Infection | Digestive Infection | Biliary Infection | Expanded-spectrum Beta-lactamase Producing ESBL
Universidad Complutense de Madrid

Completed

Use of Probiotic Lactobacilli for the Treatment of Lactational Mastitis

Mastitis

Spain
Groupe Hospitalier Paris Saint Joseph

Recruiting

Evaluation of Pharmacokinetic / Pharmacodynamic and Tolerance Assessment of Dermal Administration of Beta-lactams in the Elderly (BETALACUTANE)

Beta-Lactams | Aged Subject

France
Suzhou Erye Pharmaceutical Co., Ltd.

Recruiting

Study of the Safety, Tolerability, and PK of SZEY-2108 Administered Intravenously to HVs in SAD and MAD Cohorts

Infections

China
Qilu Hospital of Shandong University

Not yet recruiting

Prolonged Intravenous Infusion of β-lactam Antibiotics in Early Septic Patients (PROBES)

Sepsis
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR)

Recruiting

BALANCE+ Vanguard Phase (BALANCE+)

Gram-negative Bacteremia

Canada
Johns Hopkins University
Cairo University; United States Agency for International Development (USAID); World Health Organization and other collaborators

Completed

Treatment of Group A Beta Hemolytic Streptococcal Pharyngitis in Children in Low Resource Settings (TOPS)

Streptococcal Infections | Pharyngitis

Egypt, Croatia, Brazil
Tri-Service General Hospital

Completed

A Single-Dose Pharmacokinetics Study of Tapimycin Injection

Healthy
Central Hospital, Nancy, France

Unknown

Serum and Peritoneal Concentration in Antibiotics During the Surgical Management of Peritonitis (SPAC)

Critical Illness | Peritonitis

France
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

Safety, Tolerability, Pharmacokinetics of Intravenous RPX7009 in Healthy Adult Subjects

Bacterial Infections | Healthy Volunteers

Australia
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

Safety Study of Intravenous Biapenem (RPX2003) and RPX7009 Given Alone and in Combination

Bacterial Infections | Healthy Volunteers

Australia
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

Safety, Tolerability, Pharmacokinetics of Intravenous RPX2014 and RPX7009 in Healthy Adult Subjects

Bacterial Infections | Healthy Volunteers

Australia
University Hospital, Montpellier

Terminated

Negative Predictive Value of Drug Provocation Tests to Beta-lactams (NPVDPT)

Drug Hypersensitivity

France
Haiphong University of Medicine and Pharmacy

Completed

Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD (COPD)

COPD Exacerbation Acute

Vietnam
Pfizer
Allergan

Terminated

Evaluation of Pharmacokinetics, Safety, and Tolerability of Ceftazidime-avibactam in Neonates and Infants. (NOOR)

Gram-negative Bacterial Infection

United States, Hungary, Slovakia, Taiwan, India, Estonia, Greece, Italy
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Department of Health and Human Services

Recruiting

Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infections (TANGOKIDS)

Bacterial Infections

United States
Pfizer

Completed

A Study Of Intravenous Sulopenem And Oral PF-03709270 In Community Acquired Pneumonia That Requires Hospitalization

Pneumonia, Bacterial

United States, Australia, Canada, Korea, Republic of, Poland
Hellenic Institute for the Study of Sepsis

Completed

Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumonia (ACCESS)

Sepsis | Mortality | Inflammatory Response | Biomarkers | SIRS | Community-acquired Pneumonia

Greece
Fundación Pública Andaluza para la gestión de la...
Spanish Network for Research in Infectious Diseases

Completed

Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae (SIMPLIFY)

Enterobacteriaceae Infections

Spain
Rexahn Pharmaceuticals, Inc.

Completed

Efficacy Study of RX-10100 to Treat Erectile Dysfunction (ED)

Erectile Dysfunction (ED)

United States
Iterum Therapeutics, International Limited

Active, not recruiting

Oral Sulopenem Versus Amoxicillin/Clavulanate for Uncomplicated Urinary Tract Infection in Adult Women (REASSURE)

Cystitis | Urinary Tract Infections

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

A Phase II Study of Faropenem in the Treatment of Adult Community-acquired Bacterial Pneumonia

Community Acquired Pneumonia

China
Pfizer

Completed

Retrospective Chart Review Study to Assess Characteristics, Treatment Outcomes and Resource Use of Adults Hospitalized for CAP and CSSTi Treated With Zinforo in Multiple Countries

Community Acquired Pneumonia | Complicated Skin and Soft Tissue Infection

Spain, Brazil, Colombia, France, Greece, Italy, Russian Federation
University of Athens
KAT Hospital of Athens

Completed

Teicoplanin Prophylaxis for Total Hip or Knee Arthroplasty

Total Hip and Knee Arthroplasties

Greece
Central Hospital, Nancy, France
PAPE Elise

Not yet recruiting

Peritoneal Diffusion and Efficacy of Antibiotic Therapy in Pediatric Peritonitis (DIFFUPERPED)

Appendicitis | Peritonitis | Children, Only | Antibiotic Toxicity
Fundación Pública Andaluza para la gestión de la...

Completed

Evaluation of an Antibiotic Regimen Pharmacokinetic Applicable to Enterococcus Faecalis Infective Endocarditis

Infectious Endocarditis

Spain
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Department of Health and Human Services

Completed

Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults

Bacteremia | Acute Pyelonephritis | Ventilator-associated Bacterial Pneumonia | Urinary Tract Infection Complicated | Hospital Acquired Bacterial Pneumonia | Abdominal Infection

Italy, United States, Colombia, Greece, Israel, Brazil, Argentina, United Kingdom
First Affiliated Hospital of Zhejiang University

Recruiting

Clinical Study on Monitoring the Plasma Concentration of Ceftazidime-Avibactam in Critically Ill Patients

Severe Sepsis

China
Johns Hopkins All Children's Hospital

Completed

Antibiotic Instillation in Appendicitis

Complicated Appendicitis | Acute Appendicitis

United States

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