Search clinical trials for: Botulinum neurotoxin type A, free of complexing proteins

Total 815 results

Merz Pharmaceuticals GmbH

Completed

Evaluate the Migration Potential of Xeomin® Compared to Two Other Botulinum Toxin Type A Products

Healthy

Germany
Evolus, Inc.

Completed

Safety Study of DWP-450 (Botulinum Purified Neurotoxin, Type A) Injection to Treat Glabellar Lines (EV-004)

Glabellar Frown Lines

United States
Merz Pharmaceuticals GmbH

Withdrawn

Effect of NT 201 (Botulinum Neurotoxin Type A Free of Complexing Proteins) on Sleep-related Breathing Disorders (Snoring)

Sleep-Disordered Breathing
Merz Pharmaceuticals GmbH

Completed

Finding of Optimal Dose for NT 201 in the Treatment of Glabellar Frown Lines

Glabellar Frown Lines

Germany
Merz Pharmaceuticals GmbH

Completed

IncobotulinumtoxinA (Xeomin) for Upper Limb Spasticity (NT-Spin)

Upper Limb Spasticity

France, Spain, Switzerland, United Kingdom, Italy, Austria, Germany, Portugal
Seton Healthcare Family

Completed

The Treatment of Depression With Botulinum Type A Toxin

Depression

United States
Hospital Vall d'Hebron
Allergan

Unknown

Application of Botulinum Toxin Type A in Salivary Glands in the Treatment of Drooling in Patients With Cerebral Palsy

Cerebral Palsy | Sialorrhea

Spain
Merz Therapeutics GmbH

Recruiting

A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury (PaiNT)

Moderate to Severe Chronic Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) or Peripheral Nerve Injury

Bulgaria, Germany, Poland, France, Hungary, Spain
Merz Pharmaceuticals GmbH

Completed

Botulinum Toxin A to Treat Arm Tremor

Essential Tremor of the Upper Limbs

United States, Canada
Merz Pharmaceuticals GmbH

Completed

A Study to Evaluate the Distribution of Botulinum Neurotoxin Type A Administered as Intradermal Injections, Comparing Different Doses, Concentrations, and Delivery Methods

N/A, as no Specific Medical Condition Will be Treated

Germany
Merz Pharmaceuticals GmbH

Completed

A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm

Essential Tremor of the Upper Limb

United States, Canada, Poland
Merz Aesthetics GmbH
Merz Pharmaceuticals GmbH

Completed

Study to Investigate the Safety and Duration of Effect of Different Botulinum Toxin A (NT 201) Dose Groups Following the Treatment of Glabellar Frown Lines

Moderate to Severe Glabellar Frown Lines

United States, Germany
Merz Pharmaceuticals GmbH

Terminated

Blepharospasm Short Interval

Blepharospasm

Germany
Merz Pharmaceuticals GmbH

Recruiting

Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury (PATTERN)

Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury

United States, Belgium, Czechia, France, Germany, Italy, Poland, Spain, Switzerland, United Kingdom, Australia, Hungary, Norway, Slovakia, Ukraine, Russian Federation
Merz Pharmaceuticals GmbH

Completed

NT 201 (Xeomin®/Bocouture®) in Comparison With Clostridium Botulinum Toxin Type A in the Treatment of Glabellar Frown Lines (Head2Head)

Glabellar Frown Lines

United Kingdom, Germany, Austria
Merz Pharmaceuticals GmbH
LLC Merz Pharma, Russia

Completed

Treatment With Xeomin Versus Botox in Children With Spastic Equine and Equinovarus Foot Deformation in Pediatric Cerebral Palsy (XEBEC)

Cerebral Palsy | Spastic Paraplegia and Hemiparesis | Equine and Equinovarus Foot Deformation

Russian Federation
Merz North America, Inc.

Completed

The Treatment of Glabellar Frown Lines

Glabellar Frown Lines

United States
Merz Pharmaceuticals GmbH

Completed

Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability (SIPEXI)

Stroke | Cerebral Palsy | Intellectual Disability | Traumatic Brain Injury | Chronic Troublesome Sialorrhea

Georgia, Hungary, Poland, Russian Federation, Serbia, Ukraine
Merz Pharmaceuticals GmbH

Completed

Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Lateral Canthal Lines) in Subjects With Moderate to Severe Upper Facial Lines (ULTRA I)

Moderate to Severe Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines, and Lateral Canthal Lines)

United States
Merz Pharmaceuticals GmbH

Completed

Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Crows Feet) in Subjects With Moderate to Severe Upper Facial Lines. (ULTRA II)

Moderate to Severe Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines, and Lateral Canthal Lines)

Germany
Allergan

Completed

BOTOX® for the Treatment of Platysma Prominence

Platysma Prominence

United States, Canada
Merz Therapeutics GmbH
Heinrich-Heine University, Duesseldorf

Recruiting

Assessment of Long-term Clinical Response to BoNT in Cervical Dystonia (RELY-CD)

Cervical Dystonia

Germany
Merz Pharmaceuticals GmbH

Completed

Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological Conditions (SIAXI)

Parkinson's Disease | Traumatic Brain Injury | Chronic Troublesome Sialorrhea | Post-stroke

Germany, Poland
Merz Pharmaceuticals GmbH

Completed

Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy

Lower Limb and Combined Lower Limb and Upper Limb Spasticity Due to Cerebral Palsy

Poland, Austria, Czechia, Estonia, Germany, Israel, Korea, Republic of, Romania, Russian Federation, Slovakia, Turkey, Ukraine
OHSU Knight Cancer Institute
Oregon Health and Science University

Recruiting

Endoscopic Botulinum Toxin Injection in the Prevention of Postoperative Pancreatic Fistula Following Distal Pancreatectomy

Pancreatic Carcinoma

United States
Abdel-Maguid Ramzy

Completed

Injection of Botox in the Perineal Muscles in Resistant Cases of Vaginal Spasm (VginsmsBOTOX)

Vaginismus

Egypt
Evolus, Inc.
PPD

Completed

A Phase III Study to Demonstrate the Safety and Efficacy of DWP-450 to Treat Glabellar Lines - EV-002 (EV-002)

Glabellar Frown Lines

United States
Evolus, Inc.
PPD

Completed

A Phase III Study to Demonstrate the Safety and Efficacy of DWP-450 to Treat Glabellar Lines - EV001

Glabellar Frown Lines

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Tetracycline in Preventing Skin Rash in Patients Who Are Receiving Drugs Such as Gefitinib and Cetuximab for Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
Merz Pharmaceuticals GmbH

Completed

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Abnormal Contraction or Twitch of the Eyelid

Bilateral Blepharospasm (BEB)

Greece, Malaysia, Sri Lanka
Merz Pharmaceuticals GmbH

Completed

IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Glabellar Frown Lines

Moderate to Severe Glabellar Frown Lines

United States
Merz Pharmaceuticals GmbH

Completed

IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Glabellar Frown Lines No. 2

Moderate to Severe Glabellar Frown Lines

United States, Canada
Mohamed Hayder Oleish Salih

Completed

Split-face Study: Cosmetic Botulinum Toxin Type A Injection Under Electromyography-guidance Versus Conventional Palpation Technique

Glabellar Frown Lines | Wrinkle | Facial Expression | Rhytides

Egypt
Merz Pharmaceuticals GmbH

Completed

Safety and Efficacy of NT 201 (IncobotulinumtoxinA [Xeomin]) in the Treatment of Glabellar Frown Lines

Glabellar Lines

United States, Germany, Canada
Roswell Park Cancer Institute

Completed

Botulinum Toxin Type A in Preventing Complications After Surgery in Patients With Esophageal Cancer

Esophageal Carcinoma

United States
Western University, Canada

Unknown

Kinematic-guided BoNT-A Treatment for ET and PD Tremor

Tremor
Presidio Ospedaliero Garibaldi-Centro
University of Padova; University of Catania; Carlo Besta Neurological Institute

Completed

Botulinum Toxin in Burning Mouth Syndrome

Burning Mouth Syndrome
DeNova Research

Terminated

Safety and Efficacy of the Use of Botox on Acne

Acne Vulgaris

United States
Allergan

Terminated

Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Neurogenic Overactive Bladder

Overactive Bladder

Serbia, Turkey, Greece, Egypt, Lebanon, India
Merz Pharmaceuticals GmbH

Completed

Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy (XARA)

Cerebral Palsy | Spasticity

Poland, Russian Federation, Ukraine, United States, Argentina, Mexico
Mentor Worldwide, LLC
Synteract, Inc.

Completed

Safety and Efficacy Study of Repeat Treatment With PurTox® Botulinum Toxin Type A for Frown Lines Between the Eyebrows (PT-03b)

Glabellar Rhytides | Frown Lines Between the Eyebrows

United States
Merz Pharmaceuticals GmbH

Completed

Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Leg(s) in Cerebral Palsy

Lower Limb Spasticity Due to Cerebral Palsy

Poland, Austria, Czechia, Estonia, France, Germany, Israel, Korea, Republic of, Romania, Russian Federation, Slovakia, Spain, Turkey, Ukraine
Evolus, Inc.
PPD

Completed

Safety Study of DWP-450 (Botulinum Toxin, Type a) to Treat Glabellar Lines - EV-006 (EV-006)

Glabellar Frown Lines

United States
Cady, Roger, M.D.
Allergan

Completed

Calcitonin Gene-related Peptide Levels in Chronic Migraine

Chronic Migraine

United States
Daewoong Pharmaceutical Co. LTD.

Completed

A Randomized, Double Blind, Multi-center, Active Drug Controlled, Phase III Clinical Trial to Compare the Safety and Efficacy of DWP450 Versus Botox® in Treatment of Post Stroke Upper Limb Spasticity

Stroke | Spasticity

Korea, Republic of
Mentor Worldwide, LLC
Quintiles, Inc.

Completed

Safety and Efficacy Study of PurTox® Botulinum Toxin Type A to Treat Frown Lines Between the Eyebrows (PT-03a)

Glabellar Rhytides

United States
Allergan

Completed

Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Neurogenic Overactive Bladder

Overactive Bladder

Portugal, South Africa, Netherlands, Canada, Singapore, Brazil, United States, Taiwan, Italy, United Kingdom, France, Spain
Mentor Worldwide, LLC

Completed

PurTox (Botulinum Toxin Type A) for the Treatment of Adult Onset Spasmodic Torticollis/Cervical Dystonia

Spasmodic Torticollis

United States
Allergan

Completed

Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Neurogenic Overactive Bladder

Overactive Bladder

United Kingdom, Belgium, New Zealand, France, Russian Federation, Czech Republic, United States, Germany, Austria, Poland, Slovakia, Ukraine, Canada, Australia
Cady, Roger, M.D.
Allergan

Completed

A Study to Evaluate the Tolerability of Botox and Topiramate or Botox and Placebo and Effect on Cognitive Efficiency

Chronic Migraine

United States

Search clinical trials for: Botulinum neurotoxin type A, free of complexing proteins

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