Search clinical trials for: Busulphan

Total 556 results

Gruppo Italiano Trapianto di Midollo Osseo

Completed

Busulfan (BU) Plus Fludarabine Vs Intravenous BU Plus Cyclophosphamide as Conditioning Regimens Prior Allogeneic Hematopoetic Stem Cells Transplant (HSCT) in AML (GITMO-AMLR2)

Acute Myeloid Leukemia (AML)

Italy, Israel
Shanghai General Hospital, Shanghai Jiao Tong University...
Changhai Hospital; Xiangya Hospital of Central South University; Tongji Hospital and other collaborators

Recruiting

CBA Versus FBA Conditioning Followed by Allogeneic HSCT in Treatment of High Risk and Refractory AML

High Risk Acute Myeloid Leukemia | Allogeneic Hematopoeitic Stem Cell Transplantation

China
Shanghai General Hospital, Shanghai Jiao Tong University...
Changhai Hospital; Xiangya Hospital of Central South University; Tongji Hospital and other collaborators

Recruiting

CBA Versus FBA Conditioning Followed by Haploidentical Allogeneic HSCT in Treatment of High Risk and Refractory AML

High Risk Acute Myeloid Leukemia | Allogeneic Hematopoeitic Stem Cell Transplantation

China
King's College Hospital NHS Trust

Terminated

Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin (FB-ATG)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
Hospital Israelita Albert Einstein

Unknown

Evaluation of Plasmatic Levels of Busulfan in Patients Undergoing Hematopoietic Stem Cell Transplantation

Acute Leukemia | Immunodeficiency | Chronic Leukemia | Lymphoproliferative Disease | Myeloproliferative Disease

Brazil
University of Birmingham
Jazz Pharmaceuticals; Adienne SA; IMPACT (funded by NHS Blood & Transplant, Anthony...

Active, not recruiting

A Trial of Treatments to Assess the Effects on Outcome of Adults With AML and MDS Undergoing Allogeneic SCT (COSI)

Acute Myeloid Leukaemia | High-risk Myelodysplastic Syndrome

United Kingdom
Gruppo Italiano Trapianto di Midollo Osseo

Completed

Study to Compare Busulfan-fludarabine With Thiotepa-fludarabine Regimen in Allogeneic Transplantation for Myelofibrosis (GITMO-MF2010)

Myelofibrosis

Italy
Institut Paoli-Calmettes

Unknown

Evaluation of 3 Different Doses of IV Busulfan (AAA)

Acute Myeloid Leukemia | Myelodysplastic Syndrome

France
University of Arizona

Completed

Peripheral Blood Stem Cell Transplantation (PBSCT)From Haploidentical Related Donors

Hematologic Neoplasms | Multiple Myeloma | Anemia, Aplastic | Hemoglobinuria, Paroxysmal

United States
Shanghai Public Health Clinical Center
R&D Kanglin Biotech

Unknown

An Efficacy and Safety Study of shRNA-modified CD34+ Cells in HIV-infected Patients.

HIV Infections | AIDS

China
City of Hope Medical Center
Sangamo Therapeutics; California Institute for Regenerative Medicine (CIRM)

Active, not recruiting

Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients

HIV

United States
European Society for Blood and Marrow Transplantation
Pierre Fabre Medicament

Terminated

Dose-reduced Versus Standard Conditioning in MDS/sAML (RICMAC)

Myelodysplastic Syndromes | Secondary Acute Myeloid Leukemia

Germany, Italy, Netherlands, Russian Federation
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Sarcoma | Lymphoma | Leukemia | Brain and Central Nervous System Tumors | Metastatic Cancer | Retinoblastoma | Childhood Germ Cell Tumor

United States
Baylor Research Institute
Genzyme, a Sanofi Company

Completed

Study of Stem Cell Transplant for Leukemia and Myelodysplastic Syndromes Using Clofarabine and Busulfan Regimen

Leukemia | Myelodysplastic Syndrome

United States
Duke University
National Cancer Institute (NCI)

Completed

Intrathecal Busulfan in Treating Patients With Recurrent, Refractory, or Metastatic Leptomeningeal Tumors

Brain and Central Nervous System Tumors

United States
Alberta Health services

Unknown

Busulfan and Fludarabine as Conditioning for Allogeneic Stem Cell Transplantation: a Pharmacokinetic Study

Hematologic Malignancy

Canada
Institut Paoli-Calmettes

Not yet recruiting

Sequential and Personalized PK-guided Busulfan Administration in the Frame of the Conditiong Regimen for Allo-HSCT in Patients With Malignant Hemopathies Ineligible for the Standard Myeloablative Conditioning (BUSEQ)

Acute Leukemia | Myeloproliferative Neoplasm | Mielodysplasic Syndrome
University of Arizona

Completed

Reduced Intensity Allogeneic PBSCT to Treat Hematologic Malignancies and Hematopoietic Failure States (ALBUM)

Hematologic Neoplasms | Multiple Myeloma | Myelofibrosis | Anemia, Aplastic | Hemoglobinuria, Paroxysmal

United States
Shanghai Jiao Tong University School of Medicine

Recruiting

Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes

China
Vastra Gotaland Region

Recruiting

Studying Conditioning Regimen In Pediatric Transplantation - AML , SCRIPT-AML (SCRIPT-AML)

Stem Cell Transplantation | Acute Myeloid Leukemia (AML) in Remission

Belgium, Denmark, Finland, Hong Kong, Israel, Lithuania, Netherlands, Norway, Spain, Sweden
Memorial Sloan Kettering Cancer Center

Recruiting

Giving Chemotherapy for a Shortened Amount of Time Before a Stem Cell Transplantation

Hematologic Malignancies

United States
University Hospital, Basel, Switzerland
University Hospital, Geneva; University Hospital, Zürich

Completed

Cyclophosphamide and Busulfan as Conditioning Regimen Before Allogeneic HSCT

Myeloid Leukemia | Precursor Myeloid Neoplasms | Lymphoid Neoplasms

Switzerland
University Hospital, Clermont-Ferrand

Unknown

Haplo-identical Hematopoietic Stem Cell Transplantation Following Reduced-intensity Conditioning in Children With Neuroblastoma (Rice NK)

Neuroblastoma

France
Emory University

Completed

IMM 0212: Busulfan With Fludarabine and Antithymocyte Globulin as Preparative Therapy for Hematopoietic Stem Cell Transplant for the Treatment of Severe Congenital T-Cell Immunodeficiency

Severe Combined Immunodeficiency | T-Cell Immune Deficiency Diseases

United States
Fundacion Para La Investigacion Hospital La Fe

Unknown

Autologous Stem Cell Transplant (ASCT) With Intravenous Busulfan and Melphalan as Conditioning Regimen

Multiple Myeloma

Spain
University Hospital, Clermont-Ferrand

Unknown

Allogeneic Hematopoietic Stem Cell Transplantation (RICE)

Hematologic Neoplasms | Solid Tumors

France
The Korean Society of Pediatric Hematology Oncology

Unknown

Study of Reduced Toxicity Myeloablative Conditioning Regimen for Cord Blood Transplantation in Pediatric AML

Acute Myeloid Leukemia

Korea, Republic of
Memorial Sloan Kettering Cancer Center

Completed

Allogeneic Bone Marrow Transplantation for the Treatment of Genetic Disorders of Erythropoiesis

Sickle Cell Anemia | Genetic Disorders

United States
Swiss Pediatric Oncology Group
ALL SCTped Forum

Recruiting

ALL SCTped FORUM - Pharmacogenomic Study (add-on Study)

Acute Lymphoblastic Leukemia

Switzerland
Saladax Biomedical, Inc.

Not yet recruiting

Busulfan Sample Collection Study

Subjects Treated With Busulfan
Nantes University Hospital

Completed

Study of a Reduced-toxicity "Submyeloablative" Conditioning Regimen Prior to Allogeneic Stem Cell Transplantation in Patients With Hematological Malignancies (ITT 08-01)

Hematological Malignancies

France
Ruijin Hospital

Recruiting

Evaluate the Efficacy and Safety of Allogeneic Haematopoietic Stem Cell Transplantation With FBM Conditioning for MDS

Myelodysplastic Syndromes | Myelodysplastic Syndrome With Excess Blasts-2 | Myelodysplastic Syndrome With Excess Blasts-1

China
The Korean Society of Pediatric Hematology Oncology

Completed

Study of Reduced Toxicity Myeloablative Conditioning Regimen for Wiskott-Aldrich Syndrome (WAS)

Wiskott-Aldrich Syndrome

Korea, Republic of
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Terminated

Reduced Intensity Regimen vs Myeloablative Regimen for Myeloid Leukemia or Myelodysplastic Syndrome (BMT CTN 0901)

Leukemia, Myelocytic, Acute

United States
Janssen Research & Development, LLC

Completed

A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide

Major Depressive Disorder

United States
Tel-Aviv Sourasky Medical Center

Unknown

Busulfan and Cyclophosphamide Instead of Total Boby Irradiation (TBI) and Cyclophosphamide for Hematological Malignancies Hematocrit (HCT)

Juvenile Myelomonocytic Leukemia | Myelodysplastic Syndrome | Acute Leukemias | Chronic Leukemias
Columbia University

Terminated

Reduced Intensity AlloSCT in(CML) With Persistent Disease (CML)

Chronic Myeloid Leukemia

United States
Sichuan University

Recruiting

Fractionated Busulfan Conditioning Regimen for Allo-HSCT in Non-remission Myeloid Malignancies

Myeloid Malignancies

China
Hackensack Meridian Health

Terminated

PRO#1278: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation (FLUBUTBI)

Myeloproliferative Disorders | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Myeloid Malignancies

United States
University of Illinois at Chicago

Completed

Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies

Acute Myeloid Leukemia | Polycythemia Vera | Multiple Myeloma | Myelofibrosis | Acute Leukemia | Chronic Myelogenous Leukemia | Aplastic Anemia | Myeloproliferative Disorder | Hodgkin's Disease | Malignant Lymphoma | Lymphocytic Leukemia

United States
Institut Paoli-Calmettes

Unknown

Cladribine Dose Escalation in Conditioning Regimen Prior to Allo-HSCT for Refractory Acute Leukemia and Myelodysplastic Syndromes (CEREAL)

Leukemia, Myeloid, Acute | Leukemia, Lymphoblastic, Acute

France
Emory University

Completed

Allogeneic Bone Marrow Transplantation With Matched Unrelated Donors for Patients With Hematologic Malignancies

Hematologic Malignancies

United States
University of Michigan Rogel Cancer Center
Otsuka Pharmaceutical Development & Commercialization, Inc.

Terminated

Stem Cell Transplantation To Treat High Risk Multiple Myeloma With Reduced Toxicity Myeloablative Conditioning Regimen

Multiple Myeloma | Plasma Cell Leukemia

United States
Zou Dehui
Juventas Cell Therapy Ltd.

Active, not recruiting

CNCT19 Following ASCT in Patients With Relapsed or Refractory B-cell Lymphoma

Large B-cell Lymphoma

China
Northwestern University
National Cancer Institute (NCI)

Completed

Peripheral Stem Cell Transplantation Following Radiation Therapy in Treating Patients With Hodgkin's Disease or Non-Hodgkin's Lymphoma

Lymphoma

United States
Northwestern University
National Cancer Institute (NCI)

Completed

Bone Marrow Transplantation in Treating Patients With Multiple Myeloma, Chronic Phase Chronic Myelogenous Leukemia, or Agnogenic Myeloid Metaplasia

Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm

United States
Memorial Sloan Kettering Cancer Center
Massachusetts General Hospital; Northwestern University; University of Calgary; Schering-Ploug... and other collaborators

Completed

Intensive Chemotherapy and Autotransplantation for Patients With Newly Diagnosed Anaplastic Oligodendroglioma

CNS Cancer | CNS BRAIN

United States
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Immunoablative Mini Transplant (Hematopoietic Peripheral Blood Stem Cell Transplant [HPBSC])

Hematological Malignancies | Malignant Melanoma | Tumors | Leukemia, Lymphoblastic, Acute | Myelogenous Leukemia, Chronic

United States
Institut Paoli-Calmettes
Agence de La Biomédecine

Completed

Study Evaluating the Efficacy of Allogeneic Transplant Conditioning With Adaptive Dose Busulfan Intravenous (Busilvex®) in Patients at High Risk of Carrying Blood Diseases (BX-PK)

Hematological Diseases

France
Ruijin Hospital

Not yet recruiting

Compare the Efficacy and Safety of Dec-FB4 and FB4 as Conditioning Regimen for AML-MR

AML, Adult

China

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