Search clinical trials for: CDX 6114

Total 2526 results

Codexis Inc.

Completed

Safety and Tolerability of CDX-6114 in Healthy Volunteers

Healthy

Australia
Codexis Inc.

Completed

A Study of the Safety and Tolerability of CDX-6114 in Healthy Volunteers

Healthy

Australia
Nestlé

Completed

Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of CDX-6114 in Patients With Phenylketonuria (PKU)

Phenylketonuria

Australia, Germany
Assiut University

Not yet recruiting

Immune Markers in Pediatric ITP on Second Line Therapy

ITP - Immune Thrombocytopenia
Guy's and St Thomas' NHS Foundation Trust

Completed

Bond Failure of Two Types of Molar Buccal Tubes

Orthodontic Appliance Complication

United Kingdom
NHS Greater Glasgow and Clyde
University of Glasgow; Lamellar Biomedical Ltd

Completed

A Study of Patients With Dry Mouth and Sticky Saliva During Radiotherapy

Xerostomia

United Kingdom
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of MK-6194 (PT101) in Participants With Active Ulcerative Colitis (UC) (MK-6194-002)

Ulcerative Colitis

United States, Georgia, Germany, Hungary, Moldova, Republic of, Poland, Ukraine, United Kingdom
TargetCancer Foundation
Foundation Medicine

Recruiting

TCF-001 TRACK (Target Rare Cancer Knowledge) Study (TRACK)

Cholangiocarcinoma | Cancer of Unknown Primary Site | Rare Cancers

United States
Halia Therapeutics, Inc.

Recruiting

Evaluating Ability of HT-6184 to Reduce Inflammation and Pain After Third Molar Extraction

Pain

United States
Halia Therapeutics, Inc.
TKL Research, Inc.

Completed

Study to Evaluate HT-6184 in Healthy Subjects

Normal Healthy Subjects

United States
Assistance Publique - Hôpitaux de Paris

Completed

Injection of CD4 and CD8 + T Cells Anti-Cytomegalovirus (CMV) or Anti-adenovirus (CTLantiCMV)

Cytomegalovirus Infections | Adenovirus Infections

France
GlaxoSmithKline

Completed

A Study to Assess the Relative Bioavailability of Different Formulations of GSK2018682, a Sphingosine-1-phosphate Receptor Subtype 1 Agonist, in Healthy Volunteers. (P1A114919)

Multiple Sclerosis, Relapsing-Remitting

Australia
Washington University School of Medicine
National Cancer Institute (NCI); The Foundation for Barnes-Jewish Hospital; Celldex...

Terminated

Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
Merck Sharp & Dohme LLC

Recruiting

A Clinical Study of MK-6194 for the Treatment of Vitiligo (MK-6194-007)

Non-segmental Vitiligo

United States, Canada, Australia, Korea, Republic of, Switzerland, Germany, Spain, Chile, France, Israel, Netherlands, Japan, Belgium
FORUM Pharmaceuticals Inc
PRA Health Sciences

Completed

EVP-6124 Hepatic Impairment Study

Hepatic Impairment

Czech Republic, Poland, Slovakia
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of Two Lots of V114 in Healthy Infants (V114-008)

Pneumococcal Infections

United States, Canada, Denmark, Finland, Israel, Spain
Kazakhstan's Medical University "KSPH"
Vyacheslav Notanovich Lokshin; Nurgalieva Zhanar Zhenisovna; Manzhuova Lyazzat... and other collaborators

Completed

Health Status of Children Born After Assisted Reproductive Technologies

Child Development | Health Status | Children Born After Assisted Reproductive Technologies

Kazakhstan
Merck Sharp & Dohme LLC

Active, not recruiting

Multiple Rising Dose Study of MK-6194 in Participants With Atopic Dermatitis (MK-6194-008)

Dermatitis, Atopic

United States, Belgium, Bulgaria, Canada, Romania, Spain
Seoul National University Hospital

Unknown

Molecular Profiling in Young (<50 Years of Age) Patients With Metastatic Breast Cancer

Breast Cancer

Korea, Republic of
Celldex Therapeutics

Completed

A Study to Evaluate CDX-301 (rhuFlt3L) in Healthy Volunteers

Healthy

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability and Immunogenicity of V114 in Healthy Adults and Infants (V114-005)

Pneumococcal Infections
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability and Immunogenicity of V114 in Healthy Adults and Infants (V114-004)

Pneumococcal Infections | Streptococcus Pneumoniae Infection
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

Plasmablastic Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell... and other conditions

United States
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

Evaluation of 611 in Chinese Adults With Moderate to Severe Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

China
Merck Sharp & Dohme LLC

Recruiting

Efficacy And Safety Of MK-6194 In Adult Participants With Systemic Lupus Erythematosus (MK-6194-006)

Systemic Lupus Erythematosus

United States, Canada, Japan, Chile, France, Poland, Spain
FORUM Pharmaceuticals Inc
PRA Health Sciences

Completed

EVP-6124 Renal Impairment Study

Renal Impairment

Czech Republic, Hungary
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Active, not recruiting

A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps

Sinusitis | Nasal Polyps | Polyps

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Juno Therapeutics, Inc.

Completed

Immunotherapy With BCMA CAR-T Cells in Treating Patients With BCMA Positive Relapsed or Refractory Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma

United States
Centre Hospitalier Universitaire de Nice

Recruiting

Comparison of Inflammatory Markers and Incidence of Comorbidities in Patients on Antiretroviral Therapy With Second-generation Anti-integrase Drugs on Triple Versus Dual Therapy (COLLATERAL 2)

Hiv

France
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Completed

Evaluation of 611 in Chinese Adults With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

China
Nantes University Hospital

Completed

Study of the Frequency and of the Regulatory Function of Positive T Lymphocytes Dual CD4CD8aa (DP8a) Specific to a Bacteria of the Intestinal Microbiota (Faecalibacterium Prausnitzii) in Atopic Dermatitis, Asthma and Allergic Rhinitis (Prévall-DP)

Allergic Rhinitis | Atopic Dermatitis | Allergic Asthma

France
Addario Lung Cancer Medical Institute

Recruiting

Studying Pathways of Resistance in KRAS-driven Cancers (SPARK)

KRAS P.G12C

United States
Celldex Therapeutics

Completed

A Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria

United States, Germany
Celldex Therapeutics

Completed

A Phase 1 Study of CDX-0159

Healthy Subjects

United States
Celldex Therapeutics

Terminated

Clinical Trial of CDX-1135 in Pediatric and Adult Patients With Dense Deposit Disease

C3 Glomerulonephritis | Dense Deposit Disease | Membranoproliferative Glomerulonephritis Type II

United States
Celldex Therapeutics

Completed

A Phase 1 Study of Subcutaneous CDX-0159 in Healthy Subjects

Healthy Subjects

United States
CDx Diagnostics
Rambam Health Care Campus

Withdrawn

CDx Biopsies for Detection of Laryngopharyngeal Reflux and Laryngeal Lesions

Laryngopharyngeal Reflux | Laryngeal Disease | Laryngeal Tumor
Takeda

Completed

TAK-114 Single- and Multiple-Dose Phase 1 Study

Clinical Pharmacology

Japan
Medical University of Graz

Recruiting

Evaluation of Efficacy of Comprehensive Genomic Tumour Profiling (CGP) From Liquid and/or Tissue Biopsy in Patients With Locally Advanced and/or Metastatic Carcinoma (SOUND)

Metastatic Cancer | Locally Advanced Carcinoma

Austria
ORIC Pharmaceuticals

Completed

Effect of Food on the Pharmacokinetics of ORIC-114

Food Effect in Healthy Participants

Australia
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Completed

Study of the Safety, Tolerability and Pharmacokinetics of 611 in Adult Healthy Volunteers

Healthy

United States
Fusion Pharma LLC
Data Matrix Solutions; OCT Rus, LLC; Skolkovo Innovation Center

Unknown

Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene

Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Chronic Myeloid Leukemia

Russian Federation
Abbott

Completed

Exploratory Positron Emission Tomography (PET) Study to Evaluate the Effects of ABT-614 on [11C]-(+)-PHNO Binding Potential to D3 Receptors in the Brain

Healthy Volunteers

Canada
Abbott

Completed

A Study to Investigate the Process by Which ABT-614 is Absorbed, Distributed, Metabolized and Eliminated in Humans

Healthy

United States
Amgen

Terminated

A Study of AMG 114 Administered by Subcutaneous Injection for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies Receiving Multicycle Chemotherapy

Cancer | Anemia
FORUM Pharmaceuticals Inc

Terminated

Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease

Dementia | Alzheimer's Disease

United States, France, United Kingdom, Spain, Argentina, Canada, Netherlands, Korea, Republic of, Australia, Czech Republic, Germany, Italy, Mexico, South Africa
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Completed

Evaluation of 611 in Chinese Adult Patients With Moderate-to-Severe Atopic Dermatitis

Dermatitis, Atopic

China
Dana-Farber Cancer Institute
Harvard University; Conquer Cancer Foundation; Alex's Lemonade Stand Foundation; Sam Day Foundation

Recruiting

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD

Ewing Sarcoma of Bone | Ewing Sarcoma | Peripheral Primitive Neuroectodermal Tumor | Peripheral Primitive Neuroectodermal Tumor of Bone | High-grade Osteosarcoma | Ewing Sarcoma of Soft Tissue | Peripheral Primitive Neuroectodermal Tumor of Soft Tissue

United States
Celldex Therapeutics

Completed

A Study of CDX-0159 in Patients With Prurigo Nodularis

Prurigo Nodularis

United States, Germany, Poland
Avobis Bio, LLC
Alimentiv Inc.

Recruiting

Seeded Cells on Matrix Plug Treating Crohn's Perianal Fistulas (STOMP-II)

Crohn's Disease | Perianal Fistula

United States

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